HK1079988A1 - 感官可接受的口腔内崩解组合物 - Google Patents

感官可接受的口腔内崩解组合物 Download PDF

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Publication number
HK1079988A1
HK1079988A1 HK06100055.6A HK06100055A HK1079988A1 HK 1079988 A1 HK1079988 A1 HK 1079988A1 HK 06100055 A HK06100055 A HK 06100055A HK 1079988 A1 HK1079988 A1 HK 1079988A1
Authority
HK
Hong Kong
Prior art keywords
composition
drug
dissolution
fast
pharmaceutically acceptable
Prior art date
Application number
HK06100055.6A
Other languages
English (en)
Chinese (zh)
Inventor
T.T.勒
B.C.路德维格
J.P.里奥
B.C.路德維格
U.J.沙
K.山本
J.P.裡奧
Original Assignee
法玛西雅公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 法玛西雅公司 filed Critical 法玛西雅公司
Publication of HK1079988A1 publication Critical patent/HK1079988A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK06100055.6A 2001-09-26 2002-09-23 感官可接受的口腔内崩解组合物 HK1079988A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32535601P 2001-09-26 2001-09-26
US60/325,356 2001-09-26
PCT/US2002/030048 WO2003026697A2 (en) 2001-09-26 2002-09-23 Organoleptically acceptable intraorally disintegrating compositions

Publications (1)

Publication Number Publication Date
HK1079988A1 true HK1079988A1 (zh) 2006-04-21

Family

ID=23267542

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06100055.6A HK1079988A1 (zh) 2001-09-26 2002-09-23 感官可接受的口腔内崩解组合物

Country Status (25)

Country Link
US (1) US20030181501A1 (https=)
EP (2) EP1429736A2 (https=)
JP (2) JP2005512964A (https=)
KR (2) KR20040058189A (https=)
CN (2) CN1633281A (https=)
AP (2) AP2004002999A0 (https=)
AR (1) AR037239A1 (https=)
BR (2) BR0212778A (https=)
CA (2) CA2461630A1 (https=)
CO (2) CO5570684A2 (https=)
EA (2) EA200400352A1 (https=)
EC (1) ECSP045029A (https=)
GE (1) GEP20063856B (https=)
HK (1) HK1079988A1 (https=)
IL (2) IL160855A0 (https=)
IS (2) IS7177A (https=)
MA (2) MA27682A1 (https=)
MX (2) MXPA04002798A (https=)
NO (2) NO20041258L (https=)
OA (2) OA12707A (https=)
PL (2) PL369298A1 (https=)
TN (2) TNSN04045A1 (https=)
WO (2) WO2003026697A2 (https=)
YU (1) YU34804A (https=)
ZA (2) ZA200401953B (https=)

Families Citing this family (25)

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WO2005002557A1 (en) * 2003-07-03 2005-01-13 Warner-Lambert Company Llc Pharmaceutical compositions including an ether and selective cox-2 inhibitor and uses thereof
US20050186271A1 (en) * 2004-02-24 2005-08-25 Sheskey Paul J. Process for dispersing a fluid in a mass of solid particles
JP5551852B2 (ja) * 2004-08-10 2014-07-16 味の素株式会社 苦味の低減したナテグリニド含有製剤
WO2006070845A1 (ja) * 2004-12-28 2006-07-06 Eisai R & D Management Co., Ltd. 速崩壊性錠剤及びその製造方法
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
EP1964549A1 (en) * 2005-12-20 2008-09-03 Eisai R&D Management Co., Ltd. Orally disintegrating tablet comprising fat-soluble substance
US8865743B2 (en) 2006-01-06 2014-10-21 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8535714B2 (en) 2006-01-06 2013-09-17 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8202535B2 (en) 2006-01-06 2012-06-19 Acelrx Pharmaceuticals, Inc. Small-volume oral transmucosal dosage forms
US8252329B2 (en) 2007-01-05 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
WO2007087188A2 (en) * 2006-01-20 2007-08-02 Merck & Co., Inc. Taste-masked tablets and granules
US20070196494A1 (en) * 2006-02-17 2007-08-23 Arnaud Grenier Low-friability, patient-friendly orally disintegrating formulations
CA2687124A1 (en) * 2006-05-19 2007-12-13 Somaxon Pharmaceuticals, Inc. Low dose doxepin formulations, including buccal, sublingual and fastmelt formulations, and uses of the same to treat insomnia
EP2164460B1 (de) * 2007-06-06 2017-08-09 Basf Se Pharmazeutische formulierung für die herstellung von schnell zerfallenden tabletten
CN102046147B (zh) * 2007-06-06 2013-03-20 巴斯夫欧洲公司 用于制备快速崩解的片剂的药物配制剂
MX2009013063A (es) * 2007-06-06 2010-01-15 Basf Se Formulacion farmaceutica para la produccion de tabletas de desintegracion rapida.
JP2010529073A (ja) * 2007-06-06 2010-08-26 ビーエーエスエフ ソシエタス・ヨーロピア チュアブル錠及びトローチ剤製造のための医薬製剤
EP2604257B1 (en) * 2007-08-07 2017-06-28 Acelrx Pharmaceuticals, Inc. Oral transmucosal dosage forms comprising sufentanil and triazolam
WO2009118589A2 (en) 2008-03-24 2009-10-01 Wockhardt Research Centre Orally disintegrating compositions of rhein or diacerein
US8945592B2 (en) * 2008-11-21 2015-02-03 Acelrx Pharmaceuticals, Inc. Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same
CN102988318A (zh) * 2008-11-25 2013-03-27 田边三菱制药株式会社 口腔速崩片及其制备方法
WO2010144865A2 (en) 2009-06-12 2010-12-16 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
US20110091544A1 (en) * 2009-10-16 2011-04-21 Acelrx Pharmaceuticals, Inc. Compositions and Methods for Mild Sedation, Anxiolysis and Analgesia in the Procedural Setting
FR2968995B1 (fr) * 2010-12-16 2013-03-22 Sanofi Aventis Composition pharmaceutioue pour une administration par voie orale destinee a eviter le mesusage
CN106822007B (zh) 2015-09-11 2021-12-31 西姆莱斯股份公司 口服制剂

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474995A (en) * 1993-06-24 1995-12-12 Merck Frosst Canada, Inc. Phenyl heterocycles as cox-2 inhibitors
US5576014A (en) * 1994-01-31 1996-11-19 Yamanouchi Pharmaceutical Co., Ltd Intrabuccally dissolving compressed moldings and production process thereof
US5633272A (en) * 1995-02-13 1997-05-27 Talley; John J. Substituted isoxazoles for the treatment of inflammation
CA2178686A1 (en) * 1995-06-13 1996-12-14 Leslie G. Humber Oral formulations of s(+)-etodolac
JPH11513641A (ja) * 1995-10-20 1999-11-24 ファルマシア・アンド・アップジョン・カンパニー ブリスターパッケージ
BR9709097A (pt) * 1996-05-17 1999-08-03 Merck & Co Inc Composição farmacêutica para o tratamento de doenças mediadas por ciclooxigenase processo para tratar uma doença inflamatória suscetível de tratamento com um agente antinflamatório n o esteróide uso e forma oral de dose unitária
EP0863134A1 (en) * 1997-03-07 1998-09-09 Merck Frosst Canada Inc. 2-(3,5-difluorophenyl)-3-(4-(methyl-sulfonyl)phenyl)-2-cyclopenten-1-one useful as an inhibitor of cyclooxygenase-2
US6465009B1 (en) * 1998-03-18 2002-10-15 Yamanouchi Pharmaceutical Co., Ltd. Water soluble polymer-based rapidly dissolving tablets and production processes thereof
PL351069A1 (en) * 1999-12-08 2003-03-10 Pharmacia Corp Valdecoxib compositions
US6316029B1 (en) * 2000-05-18 2001-11-13 Flak Pharma International, Ltd. Rapidly disintegrating solid oral dosage form
US6800297B2 (en) * 2000-06-15 2004-10-05 Acusphere, Inc. Porous COX-2 inhibitor matrices and methods of manufacture thereof
CN1638739A (zh) * 2000-08-18 2005-07-13 法玛西雅厄普约翰美国公司 治疗成瘾性障碍的化合物
DK1309315T3 (da) * 2000-08-18 2006-10-09 Pharmacia Corp Hurtigt disintegrerende oral valdecoxib-formulering

Also Published As

Publication number Publication date
AR037239A1 (es) 2004-11-03
OA12707A (en) 2006-06-26
BR0212861A (pt) 2004-10-05
KR20040044990A (ko) 2004-05-31
MXPA04002798A (es) 2004-07-05
CA2461630A1 (en) 2003-04-03
EP1429736A2 (en) 2004-06-23
EA200400352A1 (ru) 2004-12-30
EA200400357A1 (ru) 2004-08-26
US20030181501A1 (en) 2003-09-25
CO5570684A2 (es) 2005-10-31
EP1490035A1 (en) 2004-12-29
WO2003026623A1 (en) 2003-04-03
AP2004002999A0 (en) 2004-03-31
NO20041532L (no) 2004-04-15
MXPA04002652A (es) 2004-06-07
JP2005506987A (ja) 2005-03-10
OA13060A (en) 2006-11-10
WO2003026697A2 (en) 2003-04-03
CN1703203A (zh) 2005-11-30
IS7177A (is) 2004-03-11
PL369298A1 (en) 2005-04-18
NO20041258L (no) 2003-03-27
GEP20063856B (en) 2006-06-26
JP2005512964A (ja) 2005-05-12
IL160848A0 (en) 2004-08-31
CA2461044A1 (en) 2003-04-03
AP2004002998A0 (en) 2004-03-31
ECSP045029A (es) 2004-04-28
WO2003026623A8 (en) 2004-09-30
IL160855A0 (en) 2004-08-31
TNSN04047A1 (fr) 2006-06-01
KR20040058189A (ko) 2004-07-03
BR0212778A (pt) 2004-12-07
PL369297A1 (en) 2005-04-18
TNSN04045A1 (fr) 2006-06-01
WO2003026697A3 (en) 2003-07-03
CO5570659A2 (es) 2005-10-31
ZA200401953B (en) 2005-05-09
MA27682A1 (fr) 2006-01-02
MA27542A1 (fr) 2005-10-03
ZA200402364B (en) 2005-01-13
YU34804A (sh) 2006-08-17
IS7178A (is) 2004-03-11
CN1633281A (zh) 2005-06-29

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