HK1073112A1 - 3-(Cyclopenten-1-yl)-benzyl- or 3-(cyclopenten-1-yl)-heteroarylmethyl-amine derivatives and use thereof as medicines for treating schizophrenia - Google Patents

3-(Cyclopenten-1-yl)-benzyl- or 3-(cyclopenten-1-yl)-heteroarylmethyl-amine derivatives and use thereof as medicines for treating schizophrenia

Info

Publication number
HK1073112A1
HK1073112A1 HK05106801A HK05106801A HK1073112A1 HK 1073112 A1 HK1073112 A1 HK 1073112A1 HK 05106801 A HK05106801 A HK 05106801A HK 05106801 A HK05106801 A HK 05106801A HK 1073112 A1 HK1073112 A1 HK 1073112A1
Authority
HK
Hong Kong
Prior art keywords
cyclopenten
benzyl
heteroarylmethyl
medicines
amine derivatives
Prior art date
Application number
HK05106801A
Other languages
English (en)
Inventor
Bernard Vacher
Stephane Cuisiat
Wouter Koek
Francis Colpaert
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Publication of HK1073112A1 publication Critical patent/HK1073112A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/298Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with manganese derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/52Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/548Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings having unsaturation outside the six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/52Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/55Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/48Aldehydo radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/94Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HK05106801A 2002-10-16 2005-08-08 3-(Cyclopenten-1-yl)-benzyl- or 3-(cyclopenten-1-yl)-heteroarylmethyl-amine derivatives and use thereof as medicines for treating schizophrenia HK1073112A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0212854A FR2845992B1 (fr) 2002-10-16 2002-10-16 Derives de 3-(cyclopenten-1yl)-benzyl-ou3-(cyclopenten-1yl)- heteroarylmethyl-amines et leur utilisation a titre de medicaments pour le traitement de la schizophrenie
PCT/FR2003/003053 WO2004035561A1 (fr) 2002-10-16 2003-10-16 Derives de 3-(cyclopenten-1-yl)-benzyl- ou 3-(cyclopenten-1-yl)-heteroarylmethyl-amines et leur utilisation a titre de medicaments pour le traitement de la schizophrenie

Publications (1)

Publication Number Publication Date
HK1073112A1 true HK1073112A1 (en) 2005-09-23

Family

ID=32050432

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05106801A HK1073112A1 (en) 2002-10-16 2005-08-08 3-(Cyclopenten-1-yl)-benzyl- or 3-(cyclopenten-1-yl)-heteroarylmethyl-amine derivatives and use thereof as medicines for treating schizophrenia

Country Status (16)

Country Link
US (2) US7163957B2 (xx)
EP (1) EP1551821B1 (xx)
JP (1) JP4566749B2 (xx)
CN (1) CN1319962C (xx)
AT (1) ATE326456T1 (xx)
AU (1) AU2003301277B2 (xx)
BR (1) BR0315365A (xx)
CA (1) CA2502528C (xx)
DE (1) DE60305339T2 (xx)
ES (1) ES2264780T3 (xx)
FR (1) FR2845992B1 (xx)
HK (1) HK1073112A1 (xx)
MX (1) MXPA05004114A (xx)
PT (1) PT1551821E (xx)
WO (1) WO2004035561A1 (xx)
ZA (1) ZA200503822B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2898601A1 (fr) * 2006-03-14 2007-09-21 Pierre Fabre Medicament Sa Procede de preparation de derives (2-(2,3-dihydro-benzofuran ou benzofuran-7-yloxy)-ethyl)-(3-cyclopenten-1-yl-benzyl) amines et intermediaire de synthese
US20090288701A1 (en) * 2008-05-23 2009-11-26 E.I.Du Pont De Nemours And Company Solar cell laminates having colored multi-layer encapsulant sheets

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05125024A (ja) * 1991-11-05 1993-05-21 Yamanouchi Pharmaceut Co Ltd 新規なアリールオキシアルキルアミン誘導体又はその塩
JPH05255302A (ja) * 1992-03-09 1993-10-05 Yamanouchi Pharmaceut Co Ltd 新規なクロマニルオキシアルキルアミン誘導体
US5955495A (en) * 1996-05-03 1999-09-21 Hoffmann-La Roche Inc. Method of treating diseases of the CNS
EP0923551B1 (en) * 1996-08-27 2002-06-05 American Home Products Corporation 4-aminoethoxy indolone derivatives
AU3386199A (en) * 1998-04-08 1999-10-25 American Home Products Corporation N-aryloxyethyl-indoly-alkylamines for the treatment of depression (5-ht1a receptor active agents)
EP1077973A2 (en) * 1998-05-14 2001-02-28 Egis Gyogyszergyar Rt. Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
FR2791676B1 (fr) 1999-03-29 2001-06-22 Pf Medicament Nouveaux derives de [(2-substitue-5-[thienyl])-benzyl]- [2-([isopropoxy-5-fluoro]-phenoxy) ethyl]-amine, leur procede de preparation et leur utilisation a titre de medicaments

Also Published As

Publication number Publication date
US7235568B2 (en) 2007-06-26
ZA200503822B (en) 2006-03-29
WO2004035561A1 (fr) 2004-04-29
CN1705653A (zh) 2005-12-07
FR2845992A1 (fr) 2004-04-23
PT1551821E (pt) 2006-09-29
JP2006508080A (ja) 2006-03-09
EP1551821B1 (fr) 2006-05-17
CN1319962C (zh) 2007-06-06
MXPA05004114A (es) 2005-06-22
CA2502528A1 (fr) 2004-04-29
US20060014827A1 (en) 2006-01-19
DE60305339D1 (de) 2006-06-22
US7163957B2 (en) 2007-01-16
JP4566749B2 (ja) 2010-10-20
FR2845992B1 (fr) 2005-02-04
ES2264780T3 (es) 2007-01-16
ATE326456T1 (de) 2006-06-15
CA2502528C (fr) 2011-12-13
US20060264471A1 (en) 2006-11-23
AU2003301277B2 (en) 2009-06-18
AU2003301277A1 (en) 2004-05-04
EP1551821A1 (fr) 2005-07-13
BR0315365A (pt) 2005-08-23
DE60305339T2 (de) 2007-02-01

Similar Documents

Publication Publication Date Title
HUP0103988A2 (en) New d3-dopamine receptor selective piperazine and piperidine compounds, process for their preparation, their and pharmaceutical compositions containing them
MX9504349A (es) Derivados de aroilpiperidina.
DE60130771D1 (de) Substituierte heterocyclische amide
EA200600925A1 (ru) Производные триазола в качестве антагонистов вазопрессина
CY1108228T1 (el) Διαρυλ-αιθερες, ως ανταγωνιστης οπιοειδους υποδοχεως
ATE272633T1 (de) Aromatische amiden
DK1277736T3 (da) Hidtil ukendte bicykliske forbindelser
DE69931393D1 (de) Antithrombotische amide
EA200600348A1 (ru) Новые соединения
ME00443B (me) Kristalni oblik tercijalne butilaminske soli perindoprila
ES2196917T3 (es) Amidas heteroaromaticas como inhibidores del factor xa`.
HUP0401649A2 (hu) Benzoxazin-, benzotiazinszármazékok és gyógyszerkészítményeik
MXPA01007940A (es) Derivados de azabicicloalcano y usos terapeuticos de los mismos.
ATE399164T1 (de) Antagonisten des opioidrezeptors
HK1073112A1 (en) 3-(Cyclopenten-1-yl)-benzyl- or 3-(cyclopenten-1-yl)-heteroarylmethyl-amine derivatives and use thereof as medicines for treating schizophrenia
MXPA05008186A (es) Derivados de quinoxalina saturados y su uso como ligandos receptores de glutamato metabotropico.
EA200600898A1 (ru) Новый способ синтеза периндоприла и его фармацевтически приемлемых солей
TW200510361A (en) Process of preparating 3-acylaminobenzofuran-2-carboxylic acid derivatives
EA200501900A1 (ru) Новый способ синтеза периндоприла и его фармацевтически приемлемых солей
EA200501925A1 (ru) Новый способ синтеза периндоприла и его фармацевтически приемлемых солей
EA200600455A1 (ru) Новый способ синтеза периндоприла и его фармацевтически приемлемых солей
EA200600456A1 (ru) Новый способ синтеза периндоприла и его фармацевтически приемлемых солей
MY135359A (en) New process for the synthesis of perindopril and pharmaceutically acceptable salts thereof
EA200401099A1 (ru) Производные гетероциклического амида
EA200601086A1 (ru) Новый способ синтеза периндоприла и его фармацевтически приемлемых солей

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20161016