HK1071748A1 - New heterocyclic oxime compounds, a process for their preparation and pharmaceutical compositions containing them - Google Patents
New heterocyclic oxime compounds, a process for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- HK1071748A1 HK1071748A1 HK05104493.9A HK05104493A HK1071748A1 HK 1071748 A1 HK1071748 A1 HK 1071748A1 HK 05104493 A HK05104493 A HK 05104493A HK 1071748 A1 HK1071748 A1 HK 1071748A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- oxime compounds
- new heterocyclic
- Prior art date
Links
- -1 heterocyclic oxime compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/04—Drugs for disorders of the urinary system for urolithiasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Ophthalmology & Optometry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0309214A FR2858321B1 (fr) | 2003-07-28 | 2003-07-28 | Nouveaux derives d'oximes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1071748A1 true HK1071748A1 (en) | 2005-07-29 |
Family
ID=33523001
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK05104493.9A HK1071748A1 (en) | 2003-07-28 | 2005-05-30 | New heterocyclic oxime compounds, a process for their preparation and pharmaceutical compositions containing them |
Country Status (31)
Country | Link |
---|---|
US (1) | US7071221B2 (de) |
EP (1) | EP1502590B1 (de) |
JP (1) | JP4406331B2 (de) |
KR (1) | KR100677013B1 (de) |
CN (1) | CN100497323C (de) |
AR (1) | AR045125A1 (de) |
AT (1) | ATE348612T1 (de) |
AU (1) | AU2004203454B2 (de) |
BR (1) | BRPI0403028A (de) |
CA (1) | CA2475137C (de) |
CY (1) | CY1106336T1 (de) |
DE (1) | DE602004003751T2 (de) |
DK (1) | DK1502590T3 (de) |
EA (1) | EA007718B1 (de) |
EG (1) | EG24967A (de) |
ES (1) | ES2279310T3 (de) |
FR (1) | FR2858321B1 (de) |
GE (1) | GEP20063896B (de) |
HK (1) | HK1071748A1 (de) |
HR (1) | HRP20070117T8 (de) |
MA (1) | MA27104A1 (de) |
MX (1) | MXPA04007257A (de) |
MY (1) | MY139278A (de) |
NO (1) | NO327257B1 (de) |
NZ (1) | NZ534334A (de) |
PL (1) | PL1502590T3 (de) |
PT (1) | PT1502590E (de) |
SG (1) | SG109010A1 (de) |
SI (1) | SI1502590T1 (de) |
UA (1) | UA80814C2 (de) |
ZA (1) | ZA200405893B (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009516730A (ja) * | 2005-11-23 | 2009-04-23 | アストラゼネカ アクチボラグ | L−アラニン誘導体 |
FR2894965B1 (fr) * | 2005-12-20 | 2008-01-25 | Servier Lab | Nouveaux derives d'oximes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2898125B1 (fr) * | 2006-03-06 | 2008-06-13 | Servier Lab | Nouveaux derives heterocycliques cycloalkyles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
JP2009539815A (ja) * | 2006-06-09 | 2009-11-19 | アストラゼネカ アクチボラグ | 固形腫瘍の治療用のa5b1アンタゴニストとしてのN−(ベンゾイル)−O−[2−(ピリジン−2−イルアミノ)エチル]−L−チロシン誘導体と関連化合物 |
FR2903404B1 (fr) * | 2006-07-10 | 2008-08-22 | Servier Lab | Nouveaux derives tetracycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
WO2008093065A1 (en) * | 2007-01-29 | 2008-08-07 | Astrazeneca Ab | L-ALANINE DERIVATIVES AS α5βL ANTAGONISTS |
WO2008125811A1 (en) * | 2007-04-11 | 2008-10-23 | Astrazeneca Ab | N-[HETEROARYLCARBONYL]-S-THIENYL-L-ALANINE DERIVATIVES AS α5β1 ANTAGONISTS |
US9193767B2 (en) | 2011-03-30 | 2015-11-24 | Brown University | Enopeptins, uses thereof, and methods of synthesis thereto |
WO2016037072A2 (en) * | 2014-09-04 | 2016-03-10 | Brown University | Enopeptin analogas and methods of use thereof |
CN104725367B (zh) * | 2015-03-13 | 2017-06-23 | 三峡大学 | 四氢苯并噻唑‑7‑酮肟药物,制备方法及其应用 |
CN104788436B (zh) * | 2015-03-13 | 2018-05-01 | 三峡大学 | 四氢苯并呋喃-4-酮肟基三唑药物,制备方法及其应用 |
WO2018049068A1 (en) | 2016-09-07 | 2018-03-15 | Pliant Therapeutics, Inc. | N-acyl amino acid compounds and methods of use |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US32769A (en) * | 1861-07-09 | Beehive | ||
US4228292A (en) * | 1978-07-20 | 1980-10-14 | Monsanto Company | N-Substituted benzothiazolines and benzoxazolines and their use as herbicides and plant growth regulants |
DE3064910D1 (en) * | 1979-06-12 | 1983-10-27 | Fujisawa Pharmaceutical Co | 2-oxo-benzothiazoline, benzoxazoline or indoline derivatives, their preparation, and pharmaceutical compositions comprising such derivatives |
EP0719140B1 (de) * | 1993-09-15 | 2007-10-31 | Daiichi Sankyo Company, Limited | Verwendung von thiazolidindionen zur vorbeugung oder verzögerung des auftretens des nichtinsulinabhängigen diabetes mellitus (niddm) |
SK111195A3 (en) * | 1994-09-13 | 1997-06-04 | Sandoz Technology Ltd | Bicyclic ethers substituted with oxazole and thiazole, process for producing thereof and pharmaceutical composition containing same |
FR2804431A1 (fr) * | 2000-02-02 | 2001-08-03 | Adir | Nouveaux derives heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
BR0110428A (pt) * | 2000-04-28 | 2003-06-17 | Sankyo Co | Composto ou um seu sal farmacologicamente aceitável, composição farmacêutica, usos de um composto ou um seu sal farmacologicamente aceitável, de um modulador de ppar gama e de um antagonista parcial, agentes que inibe a diferenciação de adipócitos, que acentua ou recupera a função osteogênica, para tratamento ou prevenção de osteoporose, que tem atividade moduladora de ppar gama, diminuidor do açúcar no sangue, para tratamento ou prevenção de diabetes melito, e, para tratamento ou prevenção |
FR2830012B1 (fr) * | 2001-09-21 | 2003-10-31 | Servier Lab | Nouveaux derives heterocycliques, leur procede de preparation et les compositions pharamaceutiques qui les contiennent |
-
2003
- 2003-07-28 FR FR0309214A patent/FR2858321B1/fr not_active Expired - Fee Related
-
2004
- 2004-07-20 CA CA2475137A patent/CA2475137C/fr not_active Expired - Fee Related
- 2004-07-21 SG SG200404504A patent/SG109010A1/en unknown
- 2004-07-23 ZA ZA200405893A patent/ZA200405893B/xx unknown
- 2004-07-26 MY MYPI20042999A patent/MY139278A/en unknown
- 2004-07-27 AT AT04291901T patent/ATE348612T1/de active
- 2004-07-27 PL PL04291901T patent/PL1502590T3/pl unknown
- 2004-07-27 EA EA200400867A patent/EA007718B1/ru not_active IP Right Cessation
- 2004-07-27 NZ NZ534334A patent/NZ534334A/en not_active IP Right Cessation
- 2004-07-27 ES ES04291901T patent/ES2279310T3/es not_active Expired - Lifetime
- 2004-07-27 GE GE5664A patent/GEP20063896B/en unknown
- 2004-07-27 AR ARP040102657A patent/AR045125A1/es unknown
- 2004-07-27 BR BR0403028-1A patent/BRPI0403028A/pt not_active IP Right Cessation
- 2004-07-27 NO NO20043188A patent/NO327257B1/no not_active IP Right Cessation
- 2004-07-27 EP EP04291901A patent/EP1502590B1/de not_active Expired - Lifetime
- 2004-07-27 DK DK04291901T patent/DK1502590T3/da active
- 2004-07-27 DE DE602004003751T patent/DE602004003751T2/de not_active Expired - Lifetime
- 2004-07-27 MA MA27805A patent/MA27104A1/fr unknown
- 2004-07-27 SI SI200430167T patent/SI1502590T1/sl unknown
- 2004-07-27 UA UA20040706233A patent/UA80814C2/xx unknown
- 2004-07-27 MX MXPA04007257A patent/MXPA04007257A/es active IP Right Grant
- 2004-07-27 PT PT04291901T patent/PT1502590E/pt unknown
- 2004-07-28 CN CNB2004100711283A patent/CN100497323C/zh not_active Expired - Fee Related
- 2004-07-28 KR KR1020040059237A patent/KR100677013B1/ko not_active IP Right Cessation
- 2004-07-28 AU AU2004203454A patent/AU2004203454B2/en not_active Ceased
- 2004-07-28 JP JP2004219545A patent/JP4406331B2/ja not_active Expired - Fee Related
- 2004-07-28 EG EG2004070320A patent/EG24967A/xx active
- 2004-07-29 US US10/902,345 patent/US7071221B2/en not_active Expired - Fee Related
-
2005
- 2005-05-30 HK HK05104493.9A patent/HK1071748A1/xx not_active IP Right Cessation
-
2007
- 2007-02-22 CY CY20071100250T patent/CY1106336T1/el unknown
- 2007-03-20 HR HR20070117T patent/HRP20070117T8/xx unknown
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Date | Code | Title | Description |
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PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20130728 |