FR2898125B1 - Nouveaux derives heterocycliques cycloalkyles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent - Google Patents

Nouveaux derives heterocycliques cycloalkyles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Info

Publication number
FR2898125B1
FR2898125B1 FR0601954A FR0601954A FR2898125B1 FR 2898125 B1 FR2898125 B1 FR 2898125B1 FR 0601954 A FR0601954 A FR 0601954A FR 0601954 A FR0601954 A FR 0601954A FR 2898125 B1 FR2898125 B1 FR 2898125B1
Authority
FR
France
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
containing same
heterocyclic derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0601954A
Other languages
English (en)
Other versions
FR2898125A1 (fr
Inventor
Aurelie Hurtevent
Helgoual Ch Jean Martial L
Pascal Carato
Nicolas Lebegue
Veronique Leclerc
Naour Morgan Le
Pascal Berthelot
Catherine Dacquet
Alain Ktorza
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0601954A priority Critical patent/FR2898125B1/fr
Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS
Priority to AU2007222292A priority patent/AU2007222292A1/en
Priority to BRPI0708586-9A priority patent/BRPI0708586A2/pt
Priority to US12/224,861 priority patent/US20090239917A1/en
Priority to TW096107525A priority patent/TW200745068A/zh
Priority to MX2008011449A priority patent/MX2008011449A/es
Priority to KR1020087024383A priority patent/KR20080099871A/ko
Priority to EA200801910A priority patent/EA200801910A1/ru
Priority to CA002643694A priority patent/CA2643694A1/fr
Priority to EP07731083A priority patent/EP1991537A2/fr
Priority to JP2008557793A priority patent/JP2009529026A/ja
Priority to CNA200780007648XA priority patent/CN101395145A/zh
Priority to PCT/FR2007/000384 priority patent/WO2007101935A2/fr
Priority to ARP070100912A priority patent/AR059749A1/es
Publication of FR2898125A1 publication Critical patent/FR2898125A1/fr
Application granted granted Critical
Publication of FR2898125B1 publication Critical patent/FR2898125B1/fr
Priority to NO20083945A priority patent/NO20083945L/no
Priority to MA31264A priority patent/MA30295B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR0601954A 2006-03-06 2006-03-06 Nouveaux derives heterocycliques cycloalkyles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent Expired - Fee Related FR2898125B1 (fr)

Priority Applications (16)

Application Number Priority Date Filing Date Title
FR0601954A FR2898125B1 (fr) 2006-03-06 2006-03-06 Nouveaux derives heterocycliques cycloalkyles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP2008557793A JP2009529026A (ja) 2006-03-06 2007-03-05 新規な複素環シクロアルキル誘導体、その製造法およびそれを含有する薬学的組成物
US12/224,861 US20090239917A1 (en) 2006-03-06 2007-03-05 Heterocyclic Cycloalkyl Compounds, a Process for their Preparation and Pharmaceutical Compositions Containing Them
TW096107525A TW200745068A (en) 2006-03-06 2007-03-05 New heterocyclic cycloalkyl compounds, a process for their preparation and pharmaceutical compositions containing them
MX2008011449A MX2008011449A (es) 2006-03-06 2007-03-05 Derivados de cicloalquilo heterociclicos novedosos, metodo para la preparacion de los mismos, y composiciones farmaceuticas que contienen los mismos.
KR1020087024383A KR20080099871A (ko) 2006-03-06 2007-03-05 신규의 헤테로싸이클릭 싸이클로알킬 유도체, 이의 제조 방법 및 이를 포함하는 약제학적 조성물
EA200801910A EA200801910A1 (ru) 2006-03-06 2007-03-05 Новые гетероциклические циклоалкильные соединения, способ их получения и фармацевтические композиции, которые их содержат
CA002643694A CA2643694A1 (fr) 2006-03-06 2007-03-05 Nouveaux derives heterocycliques cycloalkyles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
AU2007222292A AU2007222292A1 (en) 2006-03-06 2007-03-05 Novel heterocyclic cycloalkyl derivatives, method for the preparation thereof, and pharmaceutical compositions containing the same
BRPI0708586-9A BRPI0708586A2 (pt) 2006-03-06 2007-03-05 derivados heterocìclicos cicloalquilas, respectivo processo de preparo e composições farmacêuticas que contêm
CNA200780007648XA CN101395145A (zh) 2006-03-06 2007-03-05 新的杂环的环烷基衍生物、制备其的方法和包含其的药物组合物
PCT/FR2007/000384 WO2007101935A2 (fr) 2006-03-06 2007-03-05 Nouveaux derives heterocycliques cycloalkyles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP07731083A EP1991537A2 (fr) 2006-03-06 2007-03-05 Nouveaux derives heterocycliques cycloalkyles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
ARP070100912A AR059749A1 (es) 2006-03-06 2007-03-06 Derivados de benzotiazoles, procedimiento de preparacion y composiciones farmaceuticas que los contienen
NO20083945A NO20083945L (no) 2006-03-06 2008-09-16 Nye heterosykliske sykloalkylforbindelser, en fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem
MA31264A MA30295B1 (fr) 2006-03-06 2008-09-29 Nouveaux derives heterocycliques cycloalkyles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0601954A FR2898125B1 (fr) 2006-03-06 2006-03-06 Nouveaux derives heterocycliques cycloalkyles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
FR2898125A1 FR2898125A1 (fr) 2007-09-07
FR2898125B1 true FR2898125B1 (fr) 2008-06-13

Family

ID=37387383

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0601954A Expired - Fee Related FR2898125B1 (fr) 2006-03-06 2006-03-06 Nouveaux derives heterocycliques cycloalkyles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Country Status (16)

Country Link
US (1) US20090239917A1 (fr)
EP (1) EP1991537A2 (fr)
JP (1) JP2009529026A (fr)
KR (1) KR20080099871A (fr)
CN (1) CN101395145A (fr)
AR (1) AR059749A1 (fr)
AU (1) AU2007222292A1 (fr)
BR (1) BRPI0708586A2 (fr)
CA (1) CA2643694A1 (fr)
EA (1) EA200801910A1 (fr)
FR (1) FR2898125B1 (fr)
MA (1) MA30295B1 (fr)
MX (1) MX2008011449A (fr)
NO (1) NO20083945L (fr)
TW (1) TW200745068A (fr)
WO (1) WO2007101935A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101216274B1 (ko) 2011-06-17 2012-12-28 이화여자대학교 산학협력단 골다공증 완화, 예방 또는 치료효과의 신규한 화합물, 이의 제조방법 및 이를 포함하는 약학조성물

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2804431A1 (fr) * 2000-02-02 2001-08-03 Adir Nouveaux derives heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2858321B1 (fr) * 2003-07-28 2006-01-20 Servier Lab Nouveaux derives d'oximes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2868313B1 (fr) * 2004-03-31 2008-08-15 Servier Lab Nouvelle association entre un compose heterocyclique et un agent antioxydant et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
US20090239917A1 (en) 2009-09-24
AU2007222292A1 (en) 2007-09-13
BRPI0708586A2 (pt) 2011-06-07
EP1991537A2 (fr) 2008-11-19
TW200745068A (en) 2007-12-16
EA200801910A1 (ru) 2009-02-27
FR2898125A1 (fr) 2007-09-07
AR059749A1 (es) 2008-04-23
KR20080099871A (ko) 2008-11-13
MA30295B1 (fr) 2009-03-02
JP2009529026A (ja) 2009-08-13
MX2008011449A (es) 2008-09-24
NO20083945L (no) 2008-09-16
CN101395145A (zh) 2009-03-25
WO2007101935A3 (fr) 2008-02-21
CA2643694A1 (fr) 2007-09-13
WO2007101935A2 (fr) 2007-09-13

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Effective date: 20101130