HK1070921A1 - Method for determining the expression level of glutathione-s-transferase pi - Google Patents

Method for determining the expression level of glutathione-s-transferase pi

Info

Publication number
HK1070921A1
HK1070921A1 HK05103515.5A HK05103515A HK1070921A1 HK 1070921 A1 HK1070921 A1 HK 1070921A1 HK 05103515 A HK05103515 A HK 05103515A HK 1070921 A1 HK1070921 A1 HK 1070921A1
Authority
HK
Hong Kong
Prior art keywords
gst
expression level
mrna
patient
glutathione
Prior art date
Application number
HK05103515.5A
Other languages
English (en)
Inventor
Kathleen D Danenberg
Original Assignee
Response Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Response Genetics Inc filed Critical Response Genetics Inc
Publication of HK1070921A1 publication Critical patent/HK1070921A1/xx

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1085Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C12N9/1088Glutathione transferase (2.5.1.18)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y205/00Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
    • C12Y205/01Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/01018Glutathione transferase (2.5.1.18)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK05103515.5A 2001-06-14 2005-04-25 Method for determining the expression level of glutathione-s-transferase pi HK1070921A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/879,986 US6686155B2 (en) 2001-06-14 2001-06-14 Method of determining a chemotherapeutic regimen based on glutathione-S-transferase pi expression
PCT/US2002/015203 WO2002103055A1 (en) 2001-06-14 2002-05-15 METHOD OF DETERMINING A CHEMOTHERAPEUTIC REGIMEN BASED ON GLUTATHIONE-S-TRANSFERASE Pi EXPRESSION

Publications (1)

Publication Number Publication Date
HK1070921A1 true HK1070921A1 (en) 2005-06-30

Family

ID=25375288

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05103515.5A HK1070921A1 (en) 2001-06-14 2005-04-25 Method for determining the expression level of glutathione-s-transferase pi

Country Status (15)

Country Link
US (4) US6686155B2 (zh)
EP (1) EP1407047B1 (zh)
JP (2) JP4303104B2 (zh)
KR (2) KR20090060380A (zh)
CN (2) CN100494398C (zh)
AR (1) AR034342A1 (zh)
AU (1) AU2002305573B2 (zh)
CA (1) CA2450257C (zh)
ES (1) ES2457077T3 (zh)
HK (1) HK1070921A1 (zh)
IL (2) IL159301A0 (zh)
MX (1) MXPA03011632A (zh)
NZ (1) NZ530520A (zh)
TW (1) TWI338049B (zh)
WO (1) WO2002103055A1 (zh)

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US20040204435A1 (en) * 2003-04-09 2004-10-14 Joachim Liehr Alternating treatment with topoisomerase I and topoisomerase II inhibitors
US7871769B2 (en) * 2004-04-09 2011-01-18 Genomic Health, Inc. Gene expression markers for predicting response to chemotherapy
US20060115827A1 (en) * 2004-07-01 2006-06-01 University Of Southern California Genetic markers for predicting disease and treatment outcome
EP2204454A1 (en) * 2005-05-04 2010-07-07 University of South Florida Predicting treatment response in cancer subjects
US20070059753A1 (en) * 2005-09-15 2007-03-15 Tatiana Vener Detecting gene methylation
AU2008266048A1 (en) * 2007-06-15 2008-12-24 University Of South Florida Methods of diagnosing and treating cancer
AU2009339802B2 (en) * 2009-02-16 2014-07-24 Atlas Antibodies Ab RBM3 as a marker for malignant melanoma prognosis
JP5361488B2 (ja) 2009-03-24 2013-12-04 オリンパス株式会社 蛍光観察装置
JP5680442B2 (ja) * 2011-02-24 2015-03-04 シスメックス株式会社 癌細胞のタキサン系抗癌剤感受性判定方法、それを実現するためのコンピュータプログラム及び装置
GB201316027D0 (en) * 2013-09-09 2013-10-23 Almac Diagnostics Ltd Molecular diagnostic test for oesophageal cancer
WO2016104588A1 (ja) * 2014-12-26 2016-06-30 日東電工株式会社 細胞死誘導剤、細胞増殖抑制剤及び細胞の増殖異常に起因する疾患の治療用医薬組成物
CN112321489B (zh) * 2020-10-15 2022-04-19 中山大学 一种基于活性巯基和报告离子的亲电分子探针及其制备方法和应用

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US5942389A (en) * 1990-10-19 1999-08-24 Board Of Trustees Of The University Of Illinois Genes and genetic elements associated with sensitivity to cisplatin
US5204241A (en) * 1990-10-22 1993-04-20 Oxi-Gene Inc. Glutathione-S-transferase mu as a measure of drug resistance
US5654179A (en) * 1990-11-14 1997-08-05 Hri Research, Inc. Nucleic acid preparation methods
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US5346994A (en) 1992-01-28 1994-09-13 Piotr Chomczynski Shelf-stable product and process for isolating RNA, DNA and proteins
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AU6230594A (en) * 1993-02-01 1994-08-29 University Of Iowa Research Foundation, The Quartenary amine surfactants and methods of using same in isolation of rna
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CA2153215A1 (en) * 1994-07-06 1996-01-07 Lu Wang Treatment of paraffin embedded tissue for gene analysis
US6136605A (en) * 1994-08-26 2000-10-24 Wisconsin Alumni Research Foundation Glutathione S-transferase isoforms
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DE29601618U1 (de) * 1996-01-31 1996-07-04 Invitek Gmbh Vorrichtung zur gleichzeitigen multiplen Isolierung
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Also Published As

Publication number Publication date
JP4308309B2 (ja) 2009-08-05
JP2004530434A (ja) 2004-10-07
US20050019783A1 (en) 2005-01-27
EP1407047A4 (en) 2005-03-30
US20020197609A1 (en) 2002-12-26
KR20090060380A (ko) 2009-06-11
IL159301A0 (en) 2004-06-01
EP1407047A1 (en) 2004-04-14
US6686155B2 (en) 2004-02-03
MXPA03011632A (es) 2005-04-19
NZ530520A (en) 2006-10-27
TWI338049B (en) 2011-03-01
IL159301A (en) 2010-06-16
CA2450257A1 (en) 2002-12-27
ES2457077T3 (es) 2014-04-24
KR20040018269A (ko) 2004-03-02
CN100494398C (zh) 2009-06-03
CN100355770C (zh) 2007-12-19
CA2450257C (en) 2012-11-06
CN1763064A (zh) 2006-04-26
WO2002103055A1 (en) 2002-12-27
AR034342A1 (es) 2004-02-18
US7138507B2 (en) 2006-11-21
US20040241705A1 (en) 2004-12-02
JP4303104B2 (ja) 2009-07-29
AU2002305573B2 (en) 2009-01-08
US20050074775A1 (en) 2005-04-07
EP1407047B1 (en) 2014-01-22
JP2009000118A (ja) 2009-01-08
CN1541277A (zh) 2004-10-27
KR100918927B1 (ko) 2009-09-28

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20190515