HK1068622A1 - Novel heteroaryl derivatives, their preparation and use - Google Patents

Novel heteroaryl derivatives, their preparation and use

Info

Publication number
HK1068622A1
HK1068622A1 HK05100986A HK05100986A HK1068622A1 HK 1068622 A1 HK1068622 A1 HK 1068622A1 HK 05100986 A HK05100986 A HK 05100986A HK 05100986 A HK05100986 A HK 05100986A HK 1068622 A1 HK1068622 A1 HK 1068622A1
Authority
HK
Hong Kong
Prior art keywords
preparation
heteroaryl derivatives
novel heteroaryl
disorders
disorder
Prior art date
Application number
HK05100986A
Other languages
English (en)
Inventor
Mario Rottlaender
Ejner Knud Moltzen
Ivan Mikkelsen
Thomas Ruhland
Kim Andersen
Christian Krog-Jensen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of HK1068622A1 publication Critical patent/HK1068622A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK05100986A 2001-06-29 2005-02-04 Novel heteroaryl derivatives, their preparation and use HK1068622A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200101036 2001-06-29
PCT/DK2002/000435 WO2003002556A1 (en) 2001-06-29 2002-06-27 Novel heteroaryl derivatives, their preparation and use

Publications (1)

Publication Number Publication Date
HK1068622A1 true HK1068622A1 (en) 2005-04-29

Family

ID=8160598

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05100986A HK1068622A1 (en) 2001-06-29 2005-02-04 Novel heteroaryl derivatives, their preparation and use

Country Status (27)

Country Link
US (2) US20040248883A1 (xx)
EP (1) EP1399438B1 (xx)
JP (1) JP2004535449A (xx)
KR (1) KR20040019026A (xx)
CN (1) CN1310909C (xx)
AT (1) ATE312094T1 (xx)
AU (1) AU2002344949B2 (xx)
BG (1) BG108531A (xx)
BR (1) BR0210401A (xx)
CA (1) CA2451228A1 (xx)
CZ (1) CZ2004156A3 (xx)
DE (1) DE60207857T2 (xx)
DK (1) DK1399438T3 (xx)
EA (1) EA006203B1 (xx)
ES (1) ES2252471T3 (xx)
HK (1) HK1068622A1 (xx)
HU (1) HUP0400344A2 (xx)
IL (1) IL158828A0 (xx)
IS (1) IS2425B (xx)
MX (1) MXPA03011769A (xx)
NO (1) NO326514B1 (xx)
NZ (1) NZ529460A (xx)
PL (1) PL365249A1 (xx)
SI (1) SI1399438T1 (xx)
SK (1) SK652004A3 (xx)
UA (1) UA75407C2 (xx)
WO (1) WO2003002556A1 (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL366520A1 (en) * 2001-06-29 2005-02-07 H.Lundbeck A/S Novel indole derivatives
ATE424825T1 (de) 2001-07-20 2009-03-15 Psychogenics Inc Behandlung von hyperaktivitätsstörungen und aufmerksamkeitsdefiziten
CA2733145C (en) * 2003-07-02 2012-06-19 Corus Pharma, Inc. Aztreonam l-lysine and method of determining impurities therein
US7160888B2 (en) 2003-08-22 2007-01-09 Warner Lambert Company Llc [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia
DE602005016836D1 (de) 2004-11-26 2009-11-05 Janssen Pharmaceutica Nv Chotischer und anxiolytischer aktivität
EP2521723A1 (en) 2010-01-04 2012-11-14 Enantia, S.L. Process for the preparation of rivaroxaban and intermediates thereof
CN102892797A (zh) 2010-04-12 2013-01-23 湖南石油化学株式会社 使用包含噻吩稠合的环戊二烯基配体的过渡金属化合物制备烯烃-二烯共聚物的方法
WO2011129593A2 (ko) 2010-04-12 2011-10-20 호남석유화학 주식회사 티오펜-축합고리 사이클로펜타디에닐 리간드를 포함하는 전이금속 화합물을 사용한 폴리프로필렌의 제조방법
CN102858808B (zh) 2010-04-12 2015-04-01 乐天化学株式会社 用于烯烃聚合的负载型催化剂以及利用该催化剂的聚烯烃的制备方法
US8889581B2 (en) 2010-04-12 2014-11-18 Lotte Chemical Corporation Catalyst composition for olefin polymerization and preparation method for polyolefin using the same
KR100986301B1 (ko) 2010-04-12 2010-10-07 아주대학교산학협력단 테트라하이드로퀴놀린 유도체로부터 유래한 티오펜-축합고리 싸이클로펜타디에닐 4족 금속 화합물 및 이를 이용한 올레핀 중합

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2667068B1 (fr) * 1990-09-26 1994-09-09 Adir Nouvelles amines alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
PL366520A1 (en) 2001-06-29 2005-02-07 H.Lundbeck A/S Novel indole derivatives

Also Published As

Publication number Publication date
US20040248883A1 (en) 2004-12-09
CN1520410A (zh) 2004-08-11
EA200400102A1 (ru) 2004-04-29
MXPA03011769A (es) 2004-04-02
SK652004A3 (en) 2004-09-08
IL158828A0 (en) 2004-05-12
IS7021A (is) 2003-11-10
ES2252471T3 (es) 2006-05-16
KR20040019026A (ko) 2004-03-04
BR0210401A (pt) 2004-08-17
SI1399438T1 (sl) 2006-04-30
WO2003002556A1 (en) 2003-01-09
BG108531A (bg) 2004-08-31
CN1310909C (zh) 2007-04-18
UA75407C2 (en) 2006-04-17
CA2451228A1 (en) 2003-01-09
US20080027071A1 (en) 2008-01-31
IS2425B (is) 2008-10-15
NO326514B1 (no) 2008-12-22
NO20035673D0 (no) 2003-12-18
AU2002344949B2 (en) 2007-05-24
ATE312094T1 (de) 2005-12-15
EP1399438B1 (en) 2005-12-07
HUP0400344A2 (hu) 2004-09-28
CZ2004156A3 (cs) 2004-05-12
DE60207857D1 (de) 2006-01-12
NO20035673L (no) 2003-12-18
DK1399438T3 (da) 2006-04-18
PL365249A1 (en) 2004-12-27
EA006203B1 (ru) 2005-10-27
US7393845B2 (en) 2008-07-01
DE60207857T2 (de) 2006-07-20
JP2004535449A (ja) 2004-11-25
NZ529460A (en) 2005-09-30
EP1399438A1 (en) 2004-03-24

Similar Documents

Publication Publication Date Title
HK1068622A1 (en) Novel heteroaryl derivatives, their preparation and use
HUS2100028I1 (hu) ERBB I. típusú receptor tirozinkináz-gátló N4-fenil-kinazolin-4-amin származékok és rokon vegyületeik a hiperproliferatív betegségek kezelésére
RS20120158A3 (xx) Fenil-piperazin derivati kao inhibitori resorbcije serotonina
WO2002064594A3 (en) 6-substituted pyrido-pyrimidines
YU63202A (sh) Derivati 2-okso-1-pirolidina, postupci za njihovo dobijanje i njihove upotrebe
MXPA04005456A (es) Derivados de acetileno que tienen actividad antagonistica de mglur5.
MXPA03010232A (es) Compuestos de arilsulfonamida, para el tratamiento de la obesidad, de la diabetes tipo ii y de trastornos del sistema nervioso central.
PL371127A1 (en) 6-aminomorphinane derivatives, method for the production and use thereof
DE60213576D1 (de) ANTIDEPRESSIVE AZAHETEROCYCLYLMETHYL-DERIVATE VON 2,3-DIHYDRO-1,4-DIOXINOi2,3-föCHINOXALIN
MXPA03011766A (es) Novedosos derivados de indol.
MXPA05010678A (es) Derivados de 4-(2-fenilsulfanil-fenil)-1,2,3,6-tetrahidropiridina como inhibidores de recaptacion de serotonina.
MXPA04005151A (es) Compuestos terapeuticos.
ATE298742T1 (de) Zykloalkenylsulfonamidderivate
MXPA04001855A (es) Derivados de sistemas de indan-1-ol c2-sustituidos, metodos para la produccion de los mismos y su uso como medicamentos.
CO5150221A1 (es) Nuevas 3-fenoxi- y 3-fenilalquiloxi-2-fenil-propilaminas sustituidas
WO2003005969A3 (en) Tetrahydropurinones as corticotropin releasing factor
UA85198C2 (ru) Производные морфолина как ингибиторы повторного поглощения норэпинефрина
RS88803A (xx) Nova jedinjenja arilsulfonamida za lečenje gojaznosti, dijabetesa tipa ii i poremećaja cns

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20110627