HK1066211A1 - Benzo (g) quinoline derivatives for treating glaucoma and myopia - Google Patents

Benzo (g) quinoline derivatives for treating glaucoma and myopia

Info

Publication number
HK1066211A1
HK1066211A1 HK04109018.5A HK04109018A HK1066211A1 HK 1066211 A1 HK1066211 A1 HK 1066211A1 HK 04109018 A HK04109018 A HK 04109018A HK 1066211 A1 HK1066211 A1 HK 1066211A1
Authority
HK
Hong Kong
Prior art keywords
myopia
benzo
quinoline derivatives
treating glaucoma
glaucoma
Prior art date
Application number
HK04109018.5A
Other languages
English (en)
Inventor
Rudolf Markstein
Peter Gull
Villar Esteban Pombo
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of HK1066211A1 publication Critical patent/HK1066211A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK04109018.5A 2001-07-09 2004-11-15 Benzo (g) quinoline derivatives for treating glaucoma and myopia HK1066211A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01116553 2001-07-09
PCT/EP2002/007594 WO2003006458A1 (en) 2001-07-09 2002-07-08 Benzo [g] quinoline derivatives for treating glaucoma and myopia

Publications (1)

Publication Number Publication Date
HK1066211A1 true HK1066211A1 (en) 2005-03-18

Family

ID=8177978

Family Applications (1)

Application Number Title Priority Date Filing Date
HK04109018.5A HK1066211A1 (en) 2001-07-09 2004-11-15 Benzo (g) quinoline derivatives for treating glaucoma and myopia

Country Status (26)

Country Link
US (1) US7105528B2 (hu)
EP (1) EP1419149B1 (hu)
JP (2) JP5006505B2 (hu)
KR (2) KR20100007983A (hu)
CN (1) CN1293071C (hu)
AR (1) AR036131A1 (hu)
AT (1) ATE443060T1 (hu)
AU (1) AU2002328856B2 (hu)
BR (1) BR0210894A (hu)
CA (1) CA2452920C (hu)
DE (1) DE60233740D1 (hu)
EC (1) ECSP024377A (hu)
ES (1) ES2330732T3 (hu)
HK (1) HK1066211A1 (hu)
HU (1) HUP0400833A3 (hu)
IL (2) IL159255A0 (hu)
MX (1) MXPA03012039A (hu)
MY (1) MY130656A (hu)
NO (1) NO327549B1 (hu)
NZ (1) NZ530314A (hu)
PE (1) PE20030240A1 (hu)
PL (1) PL208284B1 (hu)
PT (1) PT1419149E (hu)
RU (1) RU2300532C2 (hu)
WO (1) WO2003006458A1 (hu)
ZA (1) ZA200309642B (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EG24415A (en) * 2002-03-07 2009-05-25 Novartis Ag Quinoline derivatives
US20070093507A1 (en) * 2003-09-05 2007-04-26 Lambrou George N Compositions comprising benzo (g) quinoline derivatives and prostaglandin derivatives
SG11202004461YA (en) 2017-11-24 2020-06-29 H Lundbeck As New catecholamine prodrugs for use in the treatment of parkinson's disease
US11168056B2 (en) 2019-05-20 2021-11-09 H. Lundbeck A/S Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol
US11111263B2 (en) 2019-05-20 2021-09-07 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11104697B2 (en) 2019-05-20 2021-08-31 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11130775B2 (en) 2019-05-20 2021-09-28 H. Lundbeck A/S Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4114325A1 (de) * 1991-05-02 1992-11-05 Sandoz Ag Octahydrobenzo(g)chinolin, seine herstellung und verwendung
US5262422A (en) * 1991-05-02 1993-11-16 Sandoz Ltd. Octahydrobenzo[g]quinoline
GB9326010D0 (en) * 1993-12-21 1994-02-23 Sandoz Ltd Improvements in or relating to organic compounds
TW357143B (en) 1995-07-07 1999-05-01 Novartis Ag Benzo[g]quinoline derivatives
TW378209B (en) * 1996-07-08 2000-01-01 Novartis Ag Benzo[g]quinoline derivatives, their preparation and the pharmaceutical composition containing them

Also Published As

Publication number Publication date
PL365254A1 (en) 2004-12-27
RU2300532C2 (ru) 2007-06-10
PL208284B1 (pl) 2011-04-29
IL159255A (en) 2010-05-17
EP1419149A1 (en) 2004-05-19
JP2010024243A (ja) 2010-02-04
NZ530314A (en) 2005-08-26
NO327549B1 (no) 2009-08-10
HUP0400833A3 (en) 2010-03-29
AR036131A1 (es) 2004-08-11
MXPA03012039A (es) 2004-03-26
BR0210894A (pt) 2004-06-22
JP5006505B2 (ja) 2012-08-22
DE60233740D1 (de) 2009-10-29
US7105528B2 (en) 2006-09-12
ECSP024377A (es) 2004-08-27
AU2002328856B2 (en) 2005-08-04
RU2004102398A (ru) 2005-07-10
ZA200309642B (en) 2004-10-04
CN1293071C (zh) 2007-01-03
JP2004538278A (ja) 2004-12-24
ATE443060T1 (de) 2009-10-15
PT1419149E (pt) 2009-11-25
WO2003006458A1 (en) 2003-01-23
KR20100007983A (ko) 2010-01-22
US20040171628A1 (en) 2004-09-02
IL159255A0 (en) 2004-06-01
NO20040059L (no) 2004-01-07
EP1419149B1 (en) 2009-09-16
CA2452920C (en) 2010-03-30
ES2330732T3 (es) 2009-12-15
CN1525969A (zh) 2004-09-01
PE20030240A1 (es) 2003-04-16
CA2452920A1 (en) 2003-01-23
KR101069948B1 (ko) 2011-10-04
HUP0400833A2 (hu) 2004-07-28
KR20040013126A (ko) 2004-02-11
MY130656A (en) 2007-07-31

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20140708