HK1057700A1 - Use of imidazoquinolinamines as adjuvants in dna vaccination - Google Patents
Use of imidazoquinolinamines as adjuvants in dna vaccinationInfo
- Publication number
- HK1057700A1 HK1057700A1 HK03108643.1A HK03108643A HK1057700A1 HK 1057700 A1 HK1057700 A1 HK 1057700A1 HK 03108643 A HK03108643 A HK 03108643A HK 1057700 A1 HK1057700 A1 HK 1057700A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- imidazoquinolinamines
- adjuvants
- dna vaccination
- vaccination
- dna
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0023008.6A GB0023008D0 (en) | 2000-09-20 | 2000-09-20 | Improvements in vaccination |
PCT/GB2001/004207 WO2002024225A1 (fr) | 2000-09-20 | 2001-09-20 | Utilisation d'imidazoquinolinamines comme adjuvants dans une vaccination par l'adn |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1057700A1 true HK1057700A1 (en) | 2004-04-16 |
Family
ID=9899764
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK03108643.1A HK1057700A1 (en) | 2000-09-20 | 2003-11-26 | Use of imidazoquinolinamines as adjuvants in dna vaccination |
Country Status (25)
Country | Link |
---|---|
US (3) | US20040076633A1 (fr) |
EP (1) | EP1318835B1 (fr) |
JP (1) | JP2004509150A (fr) |
KR (1) | KR100876263B1 (fr) |
CN (1) | CN1197620C (fr) |
AR (1) | AR035586A1 (fr) |
AT (1) | ATE401097T1 (fr) |
AU (2) | AU2001287908B2 (fr) |
BR (1) | BR0113982A (fr) |
CA (1) | CA2422863A1 (fr) |
CZ (1) | CZ2003792A3 (fr) |
DE (1) | DE60134866D1 (fr) |
ES (1) | ES2309086T3 (fr) |
GB (1) | GB0023008D0 (fr) |
HK (1) | HK1057700A1 (fr) |
HU (1) | HUP0301180A3 (fr) |
IL (1) | IL154947A0 (fr) |
MX (1) | MXPA03002453A (fr) |
MY (1) | MY138978A (fr) |
NO (1) | NO20031274L (fr) |
NZ (1) | NZ524792A (fr) |
PL (1) | PL360895A1 (fr) |
TW (1) | TWI287453B (fr) |
WO (1) | WO2002024225A1 (fr) |
ZA (1) | ZA200302231B (fr) |
Families Citing this family (75)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
IL139813A0 (en) | 1998-05-22 | 2002-02-10 | Loeb Health Res Inst At The Ot | Methods and products for inducing mucosal immunity |
US6677347B2 (en) * | 2000-12-08 | 2004-01-13 | 3M Innovative Properties Company | Sulfonamido ether substituted imidazoquinolines |
AU2003216852B2 (en) * | 2002-03-19 | 2008-09-11 | Glaxo Group Limited | Imidazoquinolineamines as adjuvants in HIV DNA vaccination |
DK1487485T3 (da) * | 2002-03-19 | 2011-03-14 | Powderject Res Ltd | Imidazoquinolinadjuvanser til DNA-vacciner |
GB0206461D0 (en) * | 2002-03-19 | 2002-05-01 | Glaxo Group Ltd | Improvements in vaccination |
WO2004032829A2 (fr) * | 2002-08-15 | 2004-04-22 | 3M Innovative Properties Company | Compositions immunostimulantes et procedes de stimulation d'une reponse immune |
EP1590348A1 (fr) | 2002-12-20 | 2005-11-02 | 3M Innovative Properties Company | Imidazoquinoleines a substitution aryle/heteroaryle |
US7731967B2 (en) | 2003-04-30 | 2010-06-08 | Novartis Vaccines And Diagnostics, Inc. | Compositions for inducing immune responses |
WO2005018556A2 (fr) * | 2003-08-12 | 2005-03-03 | 3M Innovative Properties Company | Composes contenant une structure imidazo a substitution hydroxylamine |
JP2007503268A (ja) * | 2003-08-25 | 2007-02-22 | スリーエム イノベイティブ プロパティズ カンパニー | 免疫応答修飾化合物の送達 |
CA2551075A1 (fr) * | 2003-08-25 | 2005-03-03 | 3M Innovative Properties Company | Combinaisons et traitements immunostimulatoires |
ES2406730T3 (es) | 2003-08-27 | 2013-06-07 | 3M Innovative Properties Company | Imidazoquinolinas sustituidas con ariloxi y arilalquilenoxi |
AU2004270201A1 (en) * | 2003-09-05 | 2005-03-17 | 3M Innovative Properties Company | Treatment for CD5+ B cell lymphoma |
US20090075980A1 (en) * | 2003-10-03 | 2009-03-19 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridines and Analogs Thereof |
CA2540541C (fr) | 2003-10-03 | 2012-03-27 | 3M Innovative Properties Company | Imidazoquinolines a substitution alcoxy |
US7544697B2 (en) | 2003-10-03 | 2009-06-09 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridines and analogs thereof |
WO2005048945A2 (fr) * | 2003-11-14 | 2005-06-02 | 3M Innovative Properties Company | Composes d'un anneau d'imidazo substitue par hydroxylamine |
EP1685129A4 (fr) | 2003-11-14 | 2008-10-22 | 3M Innovative Properties Co | Composes d'un anneau d'imidazo substitues par oxime |
JP4891088B2 (ja) | 2003-11-25 | 2012-03-07 | スリーエム イノベイティブ プロパティズ カンパニー | 置換されたイミダゾ環系および方法 |
JP2007517035A (ja) * | 2003-12-29 | 2007-06-28 | スリーエム イノベイティブ プロパティズ カンパニー | アリールアルケニルおよびアリールアルキニル置換されたイミダゾキノリン |
CA2551399A1 (fr) * | 2003-12-30 | 2005-07-21 | 3M Innovative Properties Company | Sulfonamides d'imidazoquinolinyle, d'imidazopyridinyle et d'imidazonaphtyridinyle |
CA2559863A1 (fr) * | 2004-03-24 | 2005-10-13 | 3M Innovative Properties Company | Imidazopyridines, imidazoquinolines, et imidazonaphthyridines a substitution amide |
US8017779B2 (en) * | 2004-06-15 | 2011-09-13 | 3M Innovative Properties Company | Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines |
WO2006038923A2 (fr) * | 2004-06-18 | 2006-04-13 | 3M Innovative Properties Company | Imidazonaphthyridines substituees par aryle |
US8026366B2 (en) * | 2004-06-18 | 2011-09-27 | 3M Innovative Properties Company | Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines |
US7915281B2 (en) * | 2004-06-18 | 2011-03-29 | 3M Innovative Properties Company | Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method |
WO2006009832A1 (fr) * | 2004-06-18 | 2006-01-26 | 3M Innovative Properties Company | Systemes cycliques imidazo substitues, et procedes correspondants |
WO2006026760A2 (fr) * | 2004-09-02 | 2006-03-09 | 3M Innovative Properties Company | Composes renfermant un 1-amino imidazo et procedes |
DE102004049223A1 (de) * | 2004-10-08 | 2006-04-20 | Johannes-Gutenberg-Universität Mainz | Zubereitung zum Impfen, Impfverfahren und Verwendung einer Impf-Zubereitung |
US20070243215A1 (en) * | 2004-10-08 | 2007-10-18 | Miller Richard L | Adjuvant for Dna Vaccines |
WO2006063072A2 (fr) * | 2004-12-08 | 2006-06-15 | 3M Innovative Properties Company | Compositions, combinaisons immunomodulatrices et procedes associes |
AU2005322898B2 (en) * | 2004-12-30 | 2011-11-24 | 3M Innovative Properties Company | Chiral fused (1,2)imidazo(4,5-c) ring compounds |
AU2005326708C1 (en) | 2004-12-30 | 2012-08-30 | 3M Innovative Properties Company | Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds |
AU2005321912B2 (en) * | 2004-12-30 | 2012-04-05 | 3M Innovative Properties Company | Treatment for cutaneous metastases |
CA2597092A1 (fr) | 2005-02-04 | 2006-08-10 | Coley Pharmaceutical Group, Inc. | Formulations des gel aqueux contenant des modificateurs de reponse immunitaire |
WO2006086634A2 (fr) | 2005-02-11 | 2006-08-17 | Coley Pharmaceutical Group, Inc. | Composes cycliques imidazo[4,5-c] substitues par oxime et hydroxylamine et procedes associes |
CA2602590A1 (fr) | 2005-04-01 | 2006-10-12 | Coley Pharmaceutical Group, Inc. | Composes cycliques 1-pyrazolo[3,4-c] substitues comme modulateurs de la biosynthese de cytokine destines au traitement d'infections virales et de maladies neoplastiques |
EP1869043A2 (fr) | 2005-04-01 | 2007-12-26 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridine-1,4-diamines et analogues associes |
JP2009504803A (ja) | 2005-08-22 | 2009-02-05 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | Tlrアゴニスト |
JP2009507856A (ja) * | 2005-09-09 | 2009-02-26 | コーリー ファーマシューティカル グループ,インコーポレイテッド | N−{2−[4−アミノ−2−(エトキシメチル)−1H−イミダゾ[4,5−c]キノリン−1−イル]−1,1−ジメチルエチル}メタンスルホンアミドのアミドおよびカルバマート誘導体ならびに方法 |
ZA200803029B (en) * | 2005-09-09 | 2009-02-25 | Coley Pharm Group Inc | Amide and carbamate derivatives of alkyl substituted /V-[4-(4-amino-1H-imidazo[4,5-c] quinolin-1-yl)butyl] methane-sulfonamides and methods |
JP5247458B2 (ja) * | 2005-11-04 | 2013-07-24 | スリーエム・イノベイティブ・プロパティーズ・カンパニー | ヒドロキシ及びアルコキシ置換1h−イミダゾキノリン及び方法 |
US8951528B2 (en) | 2006-02-22 | 2015-02-10 | 3M Innovative Properties Company | Immune response modifier conjugates |
WO2007106854A2 (fr) * | 2006-03-15 | 2007-09-20 | Coley Pharmaceutical Group, Inc. | 1h-imidazonaphthyridines hydroxy et alcoxy substituées, et procédés associés |
US8088788B2 (en) | 2006-03-15 | 2012-01-03 | 3M Innovative Properties Company | Substituted fused[1,2] imidazo[4,5-c] ring compounds and methods |
AU2006342608A1 (en) * | 2006-04-25 | 2007-11-01 | Intercell Ag | HCV vaccinations |
US20090060928A1 (en) * | 2006-05-26 | 2009-03-05 | Jean-Claude Bystryn | Topical Toll Like Receptor Ligands as Vaccine Adjuvants |
US8846697B2 (en) | 2006-05-31 | 2014-09-30 | The Regents Of The University Of California | Purine analogs |
AU2007263281B2 (en) * | 2006-06-20 | 2012-12-06 | Transgene S.A. | Recombinant viral vaccine |
EP3231442B1 (fr) | 2006-06-23 | 2019-12-25 | ADC Therapeutics SA | Séquences de polynucléotides et de polypeptides impliquées dans le cancer |
WO2008008432A2 (fr) * | 2006-07-12 | 2008-01-17 | Coley Pharmaceutical Group, Inc. | Composés à cycle [1,2] imidazo [4,5-c] fusionné chiral substitué et procédés correspondants |
CN100450484C (zh) * | 2006-10-11 | 2009-01-14 | 北京科信必成医药科技发展有限公司 | 一种咪喹莫特混悬溶液及其凝胶剂 |
EA019151B1 (ru) | 2007-02-07 | 2014-01-30 | Дзе Регентс Оф Дзе Юниверсити Оф Калифорния | Конъюгаты синтетических агонистов tlr и их применение |
EP2481418A1 (fr) * | 2007-02-15 | 2012-08-01 | MannKind Corporation | Procédé d'amélioration de la réponse des cellules T |
WO2009018465A1 (fr) | 2007-07-31 | 2009-02-05 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Vaccination avec des protozoaires tués mais métaboliquement actifs (kbma) avec des agonistes de récepteur de type toll |
US8815253B2 (en) | 2007-12-07 | 2014-08-26 | Novartis Ag | Compositions for inducing immune responses |
CN102245773B (zh) | 2008-11-03 | 2014-08-27 | 阿莱斯亚生物疗法股份有限公司 | 特异性地阻滞肿瘤抗原的生物活性的抗体 |
WO2010088924A1 (fr) | 2009-02-06 | 2010-08-12 | Telormedix Sa | Compositions pharmaceutiques comprenant des imidazoquinolines (amines) et des dérivés de celles-ci appropriés pour une administration locale |
US8802433B2 (en) * | 2009-12-03 | 2014-08-12 | Aureo Co., Ltd. | Macrophage phagocytosis-activating composition and/or composition promoting cytokine production in macrophages |
CN101850117B (zh) * | 2010-06-03 | 2012-05-30 | 国家兽用生物制品工程技术研究中心 | 一种复方免疫佐剂及疫苗 |
HUE033901T2 (en) | 2010-08-17 | 2018-01-29 | 3M Innovative Properties Co | Formulations and formulations for lipidized immune response modifying compounds and related processes |
BR112013025198A2 (pt) | 2011-03-31 | 2018-12-04 | Alethia Biotherapeutics Inc. | anticorpos contra antígeno 1 associado a rim e fragmentos de ligação a antígeno do mesmo |
CA2838158C (fr) | 2011-06-03 | 2019-07-16 | 3M Innovative Properties Company | Lieurs heterobifonctionnels comportant de segments de polyethylene glycol et conjugues modificateurs de reponse immunitaire obtenus a partir de ceux-ci |
JP6415979B2 (ja) | 2011-06-03 | 2018-10-31 | スリーエム イノベイティブ プロパティズ カンパニー | ヒドラジノ1h−イミダゾキノリン−4−アミン及びこれから調製された複合体 |
KR102102239B1 (ko) | 2012-01-09 | 2020-04-21 | 에이디씨 테라퓨틱스 에스에이 | 유방암을 치료하기 위한 방법 |
GB201310578D0 (en) | 2013-06-13 | 2013-07-31 | Univ Nottingham Trent | Electroactive actuators |
CN105491982B (zh) | 2013-08-12 | 2019-09-10 | 3M创新有限公司 | 用于增强透皮递送的肽 |
CA3001249C (fr) | 2015-10-12 | 2023-10-17 | Reflow Medical, Inc. | Stents pourvus d'elements saillants d'administration de medicament et systemes et procedes associes |
MX2018012249A (es) | 2016-04-19 | 2019-02-07 | Innate Tumor Immunity Inc | Moduladores de nlpr3. |
US10533007B2 (en) | 2016-04-19 | 2020-01-14 | Innate Tumor Immunity, Inc. | NLRP3 modulators |
US11697851B2 (en) | 2016-05-24 | 2023-07-11 | The Regents Of The University Of California | Early ovarian cancer detection diagnostic test based on mRNA isoforms |
TWI674261B (zh) | 2017-02-17 | 2019-10-11 | 美商英能腫瘤免疫股份有限公司 | Nlrp3 調節劑 |
WO2018217897A1 (fr) * | 2017-05-23 | 2018-11-29 | David Weiner | Méthodes et compositions pour induire une réponse immunitaire |
WO2019052975A1 (fr) | 2017-09-13 | 2019-03-21 | Sanofi Pasteur | Composition immunogène contre le cytomégalovirus humain |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL73534A (en) * | 1983-11-18 | 1990-12-23 | Riker Laboratories Inc | 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds |
IL105325A (en) * | 1992-04-16 | 1996-11-14 | Minnesota Mining & Mfg | Immunogen/vaccine adjuvant composition |
EP0958373A4 (fr) * | 1996-10-23 | 2001-11-28 | American Home Prod | Vaccins |
GB9818627D0 (en) * | 1998-08-26 | 1998-10-21 | Glaxo Group Ltd | Improvements in dva vaccination |
-
2000
- 2000-09-20 GB GBGB0023008.6A patent/GB0023008D0/en not_active Ceased
-
2001
- 2001-09-20 NZ NZ524792A patent/NZ524792A/en not_active IP Right Cessation
- 2001-09-20 HU HU0301180A patent/HUP0301180A3/hu unknown
- 2001-09-20 US US10/380,981 patent/US20040076633A1/en not_active Abandoned
- 2001-09-20 WO PCT/GB2001/004207 patent/WO2002024225A1/fr active IP Right Grant
- 2001-09-20 AU AU2001287908A patent/AU2001287908B2/en not_active Ceased
- 2001-09-20 MX MXPA03002453A patent/MXPA03002453A/es active IP Right Grant
- 2001-09-20 PL PL01360895A patent/PL360895A1/xx not_active Application Discontinuation
- 2001-09-20 DE DE60134866T patent/DE60134866D1/de not_active Expired - Lifetime
- 2001-09-20 ES ES01967535T patent/ES2309086T3/es not_active Expired - Lifetime
- 2001-09-20 BR BR0113982-7A patent/BR0113982A/pt not_active Application Discontinuation
- 2001-09-20 CA CA002422863A patent/CA2422863A1/fr not_active Abandoned
- 2001-09-20 JP JP2002528295A patent/JP2004509150A/ja active Pending
- 2001-09-20 AT AT01967535T patent/ATE401097T1/de not_active IP Right Cessation
- 2001-09-20 IL IL15494701A patent/IL154947A0/xx unknown
- 2001-09-20 EP EP01967535A patent/EP1318835B1/fr not_active Revoked
- 2001-09-20 CN CNB018186173A patent/CN1197620C/zh not_active Expired - Fee Related
- 2001-09-20 AU AU8790801A patent/AU8790801A/xx active Pending
- 2001-09-20 KR KR1020037004041A patent/KR100876263B1/ko not_active IP Right Cessation
- 2001-09-20 MY MYPI20014415A patent/MY138978A/en unknown
- 2001-09-20 AR ARP010104453A patent/AR035586A1/es unknown
- 2001-09-20 TW TW090123505A patent/TWI287453B/zh not_active IP Right Cessation
- 2001-09-20 CZ CZ2003792A patent/CZ2003792A3/cs unknown
-
2003
- 2003-03-19 NO NO20031274A patent/NO20031274L/no unknown
- 2003-03-20 ZA ZA200302231A patent/ZA200302231B/en unknown
- 2003-11-26 HK HK03108643.1A patent/HK1057700A1/xx not_active IP Right Cessation
-
2007
- 2007-06-19 US US11/764,814 patent/US20070248614A1/en not_active Abandoned
-
2010
- 2010-09-15 US US12/882,470 patent/US20110002953A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ES2309086T3 (es) | 2008-12-16 |
AR035586A1 (es) | 2004-06-16 |
NO20031274L (no) | 2003-05-19 |
NZ524792A (en) | 2004-09-24 |
CN1473051A (zh) | 2004-02-04 |
MXPA03002453A (es) | 2003-06-19 |
CZ2003792A3 (cs) | 2004-12-15 |
HUP0301180A2 (hu) | 2004-03-01 |
WO2002024225A1 (fr) | 2002-03-28 |
AU8790801A (en) | 2002-04-02 |
BR0113982A (pt) | 2003-08-19 |
HUP0301180A3 (en) | 2005-11-28 |
KR100876263B1 (ko) | 2008-12-26 |
NO20031274D0 (no) | 2003-03-19 |
US20070248614A1 (en) | 2007-10-25 |
EP1318835B1 (fr) | 2008-07-16 |
EP1318835A1 (fr) | 2003-06-18 |
US20040076633A1 (en) | 2004-04-22 |
CA2422863A1 (fr) | 2002-03-28 |
KR20040023566A (ko) | 2004-03-18 |
US20110002953A1 (en) | 2011-01-06 |
ZA200302231B (en) | 2004-05-05 |
DE60134866D1 (de) | 2008-08-28 |
IL154947A0 (en) | 2003-10-31 |
ATE401097T1 (de) | 2008-08-15 |
TWI287453B (en) | 2007-10-01 |
CN1197620C (zh) | 2005-04-20 |
PL360895A1 (en) | 2004-09-20 |
MY138978A (en) | 2009-08-28 |
GB0023008D0 (en) | 2000-11-01 |
AU2001287908B2 (en) | 2005-06-30 |
JP2004509150A (ja) | 2004-03-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1057700A1 (en) | Use of imidazoquinolinamines as adjuvants in dna vaccination | |
HUP0204250A3 (en) | Use of hiv-protein or -polynucleotide for vaccine produce | |
GB0020953D0 (en) | Vaccine | |
HUP0301092A3 (en) | Vaccine | |
IL155072A0 (en) | Vaccine | |
AU1591402A (en) | Vaccine | |
AU8207301A (en) | Purification of hbv antigens for use in vaccines | |
GB0014288D0 (en) | Vaccine | |
EP1667523A4 (fr) | Compositions issues d'un vaccin adn et leurs procedes d'utilisation | |
EP1335953A4 (fr) | Adjuvants de vaccins polynucleotidiques et formulations contenant des tensioactifs cationiques, procedes d'utilisation associes | |
GB0026334D0 (en) | Vaccine | |
GB0105606D0 (en) | Immunogens and vaccines and their preparation and use | |
GB0025694D0 (en) | Vaccine | |
GB0003082D0 (en) | Vaccine | |
GB0015722D0 (en) | Vaccine | |
GB0006693D0 (en) | Vaccine | |
GB0015935D0 (en) | Vaccine | |
GB0027644D0 (en) | Fish vaccine | |
GB0031218D0 (en) | Metgod of vaccine preparation | |
AUPR042100A0 (en) | Vaccines and methods of vaccination | |
GB0008029D0 (en) | New vaccine formulations | |
GB0016686D0 (en) | Novel vaccine | |
GB0022991D0 (en) | Vaccine | |
GB0018602D0 (en) | Vaccine | |
GB0015747D0 (en) | Vaccine |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20130920 |