HK1055424A1 - Carbamate and thiocarbamate podophyllotoxin derivatives, preparation method and pharmaceutical compositions containing them. - Google Patents

Carbamate and thiocarbamate podophyllotoxin derivatives, preparation method and pharmaceutical compositions containing them.

Info

Publication number
HK1055424A1
HK1055424A1 HK03107630A HK03107630A HK1055424A1 HK 1055424 A1 HK1055424 A1 HK 1055424A1 HK 03107630 A HK03107630 A HK 03107630A HK 03107630 A HK03107630 A HK 03107630A HK 1055424 A1 HK1055424 A1 HK 1055424A1
Authority
HK
Hong Kong
Prior art keywords
description
thiocarbamate
carbamate
preparation
pharmaceutical compositions
Prior art date
Application number
HK03107630A
Other languages
English (en)
Inventor
Claude Monneret
Emmanuel Bertounesque
Philippe Meresse
Ghanem Atassi
Alain Pierre
John Hickman
Bruno Pfeiffer
Pierre Renard
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of HK1055424A1 publication Critical patent/HK1055424A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HK03107630A 2000-06-20 2003-10-22 Carbamate and thiocarbamate podophyllotoxin derivatives, preparation method and pharmaceutical compositions containing them. HK1055424A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0007823A FR2810321B1 (fr) 2000-06-20 2000-06-20 Nouveaux derives de podophyllotoxine carbamate et thiocarbamate, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2001/001908 WO2001098307A1 (fr) 2000-06-20 2001-06-19 Derives de podophyllotoxine carbamate et thiocarbamate, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
HK1055424A1 true HK1055424A1 (en) 2004-01-09

Family

ID=8851423

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03107630A HK1055424A1 (en) 2000-06-20 2003-10-22 Carbamate and thiocarbamate podophyllotoxin derivatives, preparation method and pharmaceutical compositions containing them.

Country Status (26)

Country Link
US (1) US6878746B2 (da)
EP (1) EP1292597B1 (da)
JP (1) JP3909017B2 (da)
KR (1) KR100513575B1 (da)
CN (1) CN1191257C (da)
AR (1) AR028961A1 (da)
AT (1) ATE261975T1 (da)
AU (2) AU6919001A (da)
BR (1) BR0111854A (da)
CA (1) CA2413515C (da)
CZ (1) CZ2003172A3 (da)
DE (1) DE60102378T2 (da)
DK (1) DK1292597T3 (da)
EA (1) EA005200B1 (da)
ES (1) ES2217159T3 (da)
FR (1) FR2810321B1 (da)
HK (1) HK1055424A1 (da)
HU (1) HUP0301612A3 (da)
MX (1) MXPA02012570A (da)
NO (1) NO20026004D0 (da)
PL (1) PL359460A1 (da)
PT (1) PT1292597E (da)
SK (1) SK682003A3 (da)
TR (1) TR200400592T4 (da)
WO (1) WO2001098307A1 (da)
ZA (1) ZA200209639B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003082876A1 (en) * 2002-03-28 2003-10-09 Council Of Scientific And Industrial Research 4-beta-1''-`(2''-(substituted benzoyl)anilino! podophyllotoxin analogues useful as anticancer agents
FR2869035B1 (fr) 2004-04-16 2006-07-14 Pierre Fabre Medicament Sa Derives (poly)aminoalkylaminoacetamide d'epipodophyllotoxine leur procede de preparation et leurs applications en therapeutique comme agent anticancereux
KR101659457B1 (ko) * 2008-05-23 2016-09-23 더 유니버시티 오브 브리티쉬 콜롬비아 리포좀 나노입자에 사용하기 위한 변형된 약물
FR2935143B1 (fr) 2008-08-19 2010-12-03 Pf Medicament Nouveaus derives (poly)aminoalkylaminoalkylamides, alkyl-urees, ou alkyl-sulfonamides d'epipodophyllotoxine, leur procede de preparation et leur application en therapeuthique comme agent cancereux
CA2803646A1 (en) 2010-07-02 2012-01-05 Angiochem Inc. Short and d-amino acid-containing polypeptides for therapeutic conjugates and uses thereof
CN107964014A (zh) * 2017-10-28 2018-04-27 兰州大学 一种邻硝基芳酰化衍生物类化合物、制备方法及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES319647A1 (es) * 1964-11-18 1966-08-01 Sandoz Ag Procedimiento para la preparaciën de derivados de la podofilotoxina
JPH01117885A (ja) * 1987-10-30 1989-05-10 Dai Ichi Seiyaku Co Ltd 新規ボドフィロトキシン誘導体及びその製造法
US6566393B1 (en) * 2002-06-21 2003-05-20 The University Of North Carolina At Chapel Hill Etoposide analogs and methods of use thereof

Also Published As

Publication number Publication date
AU2001269190B2 (en) 2005-03-17
PT1292597E (pt) 2004-06-30
FR2810321A1 (fr) 2001-12-21
HUP0301612A2 (hu) 2003-09-29
FR2810321B1 (fr) 2002-07-26
ZA200209639B (en) 2003-11-27
WO2001098307A1 (fr) 2001-12-27
ATE261975T1 (de) 2004-04-15
US6878746B2 (en) 2005-04-12
DE60102378T2 (de) 2005-02-24
EP1292597A1 (fr) 2003-03-19
MXPA02012570A (es) 2003-04-10
HUP0301612A3 (en) 2005-08-29
CA2413515A1 (fr) 2001-12-27
DE60102378D1 (de) 2004-04-22
CN1191257C (zh) 2005-03-02
CZ2003172A3 (cs) 2003-05-14
PL359460A1 (en) 2004-08-23
EA200300029A1 (ru) 2003-06-26
SK682003A3 (en) 2003-05-02
US20040101574A1 (en) 2004-05-27
BR0111854A (pt) 2003-05-13
EA005200B1 (ru) 2004-12-30
AU6919001A (en) 2002-01-02
CN1437604A (zh) 2003-08-20
AR028961A1 (es) 2003-05-28
CA2413515C (fr) 2008-02-05
NO20026004L (no) 2002-12-13
DK1292597T3 (da) 2004-07-12
ES2217159T3 (es) 2004-11-01
TR200400592T4 (tr) 2004-04-21
KR100513575B1 (ko) 2005-09-09
JP3909017B2 (ja) 2007-04-25
KR20030025246A (ko) 2003-03-28
JP2004501158A (ja) 2004-01-15
NO20026004D0 (no) 2002-12-13
EP1292597B1 (fr) 2004-03-17

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090619