DK1292597T3 - Carbamat- og thiocarbamat-derivater af podophyllotoxin, fremgangsmåde til fremstilling af disse samt farmaceutiske sammensætninger indeholdende dem - Google Patents

Carbamat- og thiocarbamat-derivater af podophyllotoxin, fremgangsmåde til fremstilling af disse samt farmaceutiske sammensætninger indeholdende dem

Info

Publication number
DK1292597T3
DK1292597T3 DK01947525T DK01947525T DK1292597T3 DK 1292597 T3 DK1292597 T3 DK 1292597T3 DK 01947525 T DK01947525 T DK 01947525T DK 01947525 T DK01947525 T DK 01947525T DK 1292597 T3 DK1292597 T3 DK 1292597T3
Authority
DK
Denmark
Prior art keywords
podophyllotoxin
carbamate
processes
preparation
pharmaceutical compositions
Prior art date
Application number
DK01947525T
Other languages
English (en)
Inventor
John Hickman
Emmanuel Bertounesque
Claude Monneret
Philippe Meresse
Ghanem Atassi
Alain Pierre
Bruno Pfeiffer
Pierre Renard
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Application granted granted Critical
Publication of DK1292597T3 publication Critical patent/DK1292597T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK01947525T 2000-06-20 2001-06-19 Carbamat- og thiocarbamat-derivater af podophyllotoxin, fremgangsmåde til fremstilling af disse samt farmaceutiske sammensætninger indeholdende dem DK1292597T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0007823A FR2810321B1 (fr) 2000-06-20 2000-06-20 Nouveaux derives de podophyllotoxine carbamate et thiocarbamate, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2001/001908 WO2001098307A1 (fr) 2000-06-20 2001-06-19 Derives de podophyllotoxine carbamate et thiocarbamate, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
DK1292597T3 true DK1292597T3 (da) 2004-07-12

Family

ID=8851423

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01947525T DK1292597T3 (da) 2000-06-20 2001-06-19 Carbamat- og thiocarbamat-derivater af podophyllotoxin, fremgangsmåde til fremstilling af disse samt farmaceutiske sammensætninger indeholdende dem

Country Status (26)

Country Link
US (1) US6878746B2 (da)
EP (1) EP1292597B1 (da)
JP (1) JP3909017B2 (da)
KR (1) KR100513575B1 (da)
CN (1) CN1191257C (da)
AR (1) AR028961A1 (da)
AT (1) ATE261975T1 (da)
AU (2) AU2001269190B2 (da)
BR (1) BR0111854A (da)
CA (1) CA2413515C (da)
CZ (1) CZ2003172A3 (da)
DE (1) DE60102378T2 (da)
DK (1) DK1292597T3 (da)
EA (1) EA005200B1 (da)
ES (1) ES2217159T3 (da)
FR (1) FR2810321B1 (da)
HK (1) HK1055424A1 (da)
HU (1) HUP0301612A3 (da)
MX (1) MXPA02012570A (da)
NO (1) NO20026004L (da)
PL (1) PL359460A1 (da)
PT (1) PT1292597E (da)
SK (1) SK682003A3 (da)
TR (1) TR200400592T4 (da)
WO (1) WO2001098307A1 (da)
ZA (1) ZA200209639B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003082876A1 (en) * 2002-03-28 2003-10-09 Council Of Scientific And Industrial Research 4-beta-1''-`(2''-(substituted benzoyl)anilino! podophyllotoxin analogues useful as anticancer agents
FR2869035B1 (fr) 2004-04-16 2006-07-14 Pierre Fabre Medicament Sa Derives (poly)aminoalkylaminoacetamide d'epipodophyllotoxine leur procede de preparation et leurs applications en therapeutique comme agent anticancereux
WO2009141738A2 (en) * 2008-05-23 2009-11-26 The University Of British Columbia Modified drugs for use in liposomal nanoparticles
FR2935143B1 (fr) 2008-08-19 2010-12-03 Pf Medicament Nouveaus derives (poly)aminoalkylaminoalkylamides, alkyl-urees, ou alkyl-sulfonamides d'epipodophyllotoxine, leur procede de preparation et leur application en therapeuthique comme agent cancereux
CN103080125A (zh) 2010-07-02 2013-05-01 安吉奥开米公司 用于治疗性结合物的短且含d氨基酸的多肽及其使用
CN107964014A (zh) * 2017-10-28 2018-04-27 兰州大学 一种邻硝基芳酰化衍生物类化合物、制备方法及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1455540A (fr) * 1964-11-18 1966-10-14 Sandoz Sa Nouveaux dérivés de la podophyllotoxine et leur préparation
JPH01117885A (ja) * 1987-10-30 1989-05-10 Dai Ichi Seiyaku Co Ltd 新規ボドフィロトキシン誘導体及びその製造法
US6566393B1 (en) * 2002-06-21 2003-05-20 The University Of North Carolina At Chapel Hill Etoposide analogs and methods of use thereof

Also Published As

Publication number Publication date
FR2810321B1 (fr) 2002-07-26
US6878746B2 (en) 2005-04-12
MXPA02012570A (es) 2003-04-10
ATE261975T1 (de) 2004-04-15
JP2004501158A (ja) 2004-01-15
HUP0301612A3 (en) 2005-08-29
NO20026004D0 (no) 2002-12-13
ES2217159T3 (es) 2004-11-01
HK1055424A1 (en) 2004-01-09
KR20030025246A (ko) 2003-03-28
CZ2003172A3 (cs) 2003-05-14
BR0111854A (pt) 2003-05-13
DE60102378T2 (de) 2005-02-24
CN1191257C (zh) 2005-03-02
AU2001269190B2 (en) 2005-03-17
JP3909017B2 (ja) 2007-04-25
NO20026004L (no) 2002-12-13
CA2413515A1 (fr) 2001-12-27
PL359460A1 (en) 2004-08-23
KR100513575B1 (ko) 2005-09-09
EP1292597B1 (fr) 2004-03-17
ZA200209639B (en) 2003-11-27
DE60102378D1 (de) 2004-04-22
EP1292597A1 (fr) 2003-03-19
CN1437604A (zh) 2003-08-20
AR028961A1 (es) 2003-05-28
AU6919001A (en) 2002-01-02
PT1292597E (pt) 2004-06-30
TR200400592T4 (tr) 2004-04-21
WO2001098307A1 (fr) 2001-12-27
SK682003A3 (en) 2003-05-02
US20040101574A1 (en) 2004-05-27
FR2810321A1 (fr) 2001-12-21
HUP0301612A2 (hu) 2003-09-29
CA2413515C (fr) 2008-02-05
EA200300029A1 (ru) 2003-06-26
EA005200B1 (ru) 2004-12-30

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