HK1053303A1 - Calcium receptor active molecules - Google Patents
Calcium receptor active moleculesInfo
- Publication number
- HK1053303A1 HK1053303A1 HK03105590A HK03105590A HK1053303A1 HK 1053303 A1 HK1053303 A1 HK 1053303A1 HK 03105590 A HK03105590 A HK 03105590A HK 03105590 A HK03105590 A HK 03105590A HK 1053303 A1 HK1053303 A1 HK 1053303A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- sup
- cells
- antagonist
- receptors
- patient
- Prior art date
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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- A61K31/275—Nitriles; Isonitriles
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
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- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
- G01N33/567—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds utilising isolate of tissue or organ as binding agent
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07C2602/00—Systems containing two condensed rings
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- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US74945191A | 1991-08-23 | 1991-08-23 | |
US83404492A | 1992-02-11 | 1992-02-11 | |
US93416192A | 1992-08-21 | 1992-08-21 |
Publications (1)
Publication Number | Publication Date |
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HK1053303A1 true HK1053303A1 (en) | 2003-10-17 |
Family
ID=27419383
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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HK03105590A HK1053303A1 (en) | 1991-08-23 | 2003-08-04 | Calcium receptor active molecules |
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Country | Link |
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EP (4) | EP1632470A3 (he) |
JP (5) | JP2728564B2 (he) |
KR (1) | KR100251995B1 (he) |
CN (1) | CN1067550C (he) |
AT (2) | ATE313321T1 (he) |
AU (1) | AU711247B2 (he) |
CA (1) | CA2115828C (he) |
DE (2) | DE69233586T2 (he) |
DK (1) | DK1281702T3 (he) |
ES (1) | ES2256370T3 (he) |
HK (1) | HK1053303A1 (he) |
IL (3) | IL122958A (he) |
MX (1) | MX9204881A (he) |
NO (1) | NO940581L (he) |
RU (1) | RU2147574C1 (he) |
WO (1) | WO1993004373A1 (he) |
ZA (1) | ZA926360B (he) |
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EP1366764B1 (en) * | 1993-02-23 | 2006-06-28 | The Brigham & Women's Hospital, Inc. | Method of screening for calcium receptor-active molecules |
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AU710575B2 (en) | 1994-02-08 | 1999-09-23 | Nps Pharmaceuticals, Inc. | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
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KR100771092B1 (ko) | 1996-07-08 | 2007-10-30 | 기린 파마 가부시끼가이샤 | 칼슘 수용체 활성 화합물 |
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ES2449340T3 (es) | 2007-03-30 | 2014-03-19 | Amgen Inc. | Compuestos calcimiméticos para su uso en el tratamiento de trastornos intestinales |
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WO2010136035A2 (en) | 2009-05-27 | 2010-12-02 | Leo Pharma A/S | Novel calcium sensing receptor modulating compounds and pharmaceutical use thereof |
US8765676B2 (en) | 2009-05-27 | 2014-07-01 | Leo Pharma A/S | Calcium sensing receptor modulating compounds and pharmaceutical use thereof |
US8946474B2 (en) | 2010-06-30 | 2015-02-03 | Leo Pharma A/S | Polymorphic form of a calcimimetic compound |
CN102958907A (zh) | 2010-06-30 | 2013-03-06 | 利奥制药有限公司 | 钙敏感受体激动化合物的新多晶型 |
JP2014508104A (ja) | 2010-11-26 | 2014-04-03 | レオ ファーマ アクティーゼルスカブ | カルシウム感知受容体活性化合物 |
EP2643290A1 (en) | 2010-11-26 | 2013-10-02 | Leo Pharma A/S | Calcium-sensing receptor-active compounds |
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WO2012069402A1 (en) | 2010-11-26 | 2012-05-31 | Leo Pharma A/S | Substituted cyclopentyl - azines as casr- active compounds |
US9895325B2 (en) * | 2012-12-21 | 2018-02-20 | Synthon B.V. | Tablet composition comprising cinacalcet hydrochloride |
RU2532355C1 (ru) * | 2013-07-10 | 2014-11-10 | Общество с ограниченной ответственностью "Пробиотик Центр" | Способ лечения с.-х. птиц с помощью поликатионного соединения "тривирон" (triviron) |
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CN112250598B (zh) * | 2020-11-06 | 2023-07-25 | 河南科技大学 | 一种丹皮酚腙类衍生物及其制备方法和应用、杀虫剂 |
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FI791727A (fi) * | 1978-06-05 | 1979-12-06 | Ciba Geigy Ag | Foerfarande foer framstaellning av n-alkylerade aminoalkoholer |
CA1142954A (en) * | 1978-07-03 | 1983-03-15 | Jack Mills | Phenethanolamines, compositions containing the same, and method for effecting weight control |
ZA794872B (en) * | 1978-09-20 | 1980-11-26 | Schering Corp | A phenylalkylaminoethylsalicylamide,its preparation and pharmaceutical compositions containing it |
DD150456A5 (de) * | 1979-03-01 | 1981-09-02 | Ciba Geigy Ag | Verfahren zur herstellung von derivaten des 3-amino-1,2-propandiols |
HU183430B (en) * | 1981-05-12 | 1984-05-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing cyclodextrine inclusion complexes of n-bracket-1-phenylethyl-bracket closed-3,3-diphenylpropylamine or n-bracket-1-phenylethyl-bracket closed-3,3-diphenylpropylamine-hydrochloride |
CA1258454A (en) * | 1982-08-10 | 1989-08-15 | Leo Alig | Phenethanolamines |
US4728660A (en) * | 1984-06-11 | 1988-03-01 | University Of Miami | Method of treating diseases arising from platelet hyperactivation |
HU200591B (en) * | 1986-07-11 | 1990-07-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing new diphenyl propylamine derivatives and pharmaceutical compositions comprising such compounds |
US5386025A (en) * | 1990-02-20 | 1995-01-31 | The Salk Institute Biotechnology/Industrial Associates | Calcium channel compositions and methods |
EP0424397B1 (en) * | 1988-04-04 | 1996-06-19 | The Salk Institute Biotechnology Industrial Associates, Inc. | Calcium channel compositions and methods |
US4987084A (en) * | 1989-02-21 | 1991-01-22 | Dana Farber Cancer Institute | Method of testing the effect of a molecule on B lymphocyte function |
DD298412A5 (de) * | 1989-04-28 | 1992-02-20 | ������@���Kk�� | Verfahren zur herstellung von polypeptiden, die geeignet sind als antagonisten exzitatorischer aminosaeure-neurotransmitter und/oder blocker der calciumkanaele |
AU5957390A (en) * | 1989-07-03 | 1991-02-06 | New York University | Use of polyamines as ionic-channel regulating agents |
JP2728564B2 (ja) * | 1991-08-23 | 1998-03-18 | エヌピーエス・ファーマシウティカルズ・インコーポレイテッド | カルシウム受容体活性化分子 |
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1992
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- 1992-08-21 AT AT02016612T patent/ATE313321T1/de active
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- 1992-08-21 EP EP05077693A patent/EP1632470A3/en not_active Withdrawn
- 1992-08-21 DK DK02016612T patent/DK1281702T3/da active
- 1992-08-21 EP EP92919933A patent/EP0657029A4/en not_active Ceased
- 1992-08-21 CA CA2115828A patent/CA2115828C/en not_active Expired - Lifetime
- 1992-08-21 KR KR1019940700536A patent/KR100251995B1/ko active Protection Beyond IP Right Term
- 1992-08-21 DE DE69233572T patent/DE69233572T2/de not_active Expired - Lifetime
- 1992-08-21 RU RU94020394A patent/RU2147574C1/ru active Protection Beyond IP Right Term
- 1992-08-21 AT AT02027563T patent/ATE312347T1/de not_active IP Right Cessation
- 1992-08-21 ES ES02016612T patent/ES2256370T3/es not_active Expired - Lifetime
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- 1992-08-21 MX MX9204881A patent/MX9204881A/es unknown
- 1992-08-21 WO PCT/US1992/007175 patent/WO1993004373A1/en not_active Application Discontinuation
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- 1992-08-23 IL IL12295892A patent/IL122958A/he not_active IP Right Cessation
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- 1992-08-24 ZA ZA926360A patent/ZA926360B/xx unknown
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1994
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1996
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1998
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2000
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2003
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