HK1049449B - 結合使用偶合雌激素及黃體酮(medroxyprogesterone)醋酸鹽的激素取代治療法 - Google Patents
結合使用偶合雌激素及黃體酮(medroxyprogesterone)醋酸鹽的激素取代治療法Info
- Publication number
- HK1049449B HK1049449B HK03101651.5A HK03101651A HK1049449B HK 1049449 B HK1049449 B HK 1049449B HK 03101651 A HK03101651 A HK 03101651A HK 1049449 B HK1049449 B HK 1049449B
- Authority
- HK
- Hong Kong
- Prior art keywords
- combination
- replacement therapy
- hormone replacement
- medroxyprogesterone acetate
- conjugated estrogens
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A—HUMAN NECESSITIES
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Virology (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Biotechnology (AREA)
- Hospice & Palliative Care (AREA)
- Gynecology & Obstetrics (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19063000P | 2000-03-20 | 2000-03-20 | |
US26860701P | 2001-02-14 | 2001-02-14 | |
PCT/US2001/040302 WO2001070208A2 (en) | 2000-03-20 | 2001-03-16 | Hormone replacement therapy using a combination of conjugated estrogens and medroxyprogesterone acetate |
Publications (2)
Publication Number | Publication Date |
---|---|
HK1049449A1 HK1049449A1 (en) | 2003-05-16 |
HK1049449B true HK1049449B (zh) | 2006-07-28 |
Family
ID=26886279
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK03101651.5A HK1049449B (zh) | 2000-03-20 | 2003-03-06 | 結合使用偶合雌激素及黃體酮(medroxyprogesterone)醋酸鹽的激素取代治療法 |
Country Status (30)
Country | Link |
---|---|
US (2) | US20010034340A1 (zh) |
EP (1) | EP1265616B1 (zh) |
JP (1) | JP2003527416A (zh) |
KR (1) | KR100805648B1 (zh) |
CN (1) | CN1239160C (zh) |
AR (1) | AR031563A1 (zh) |
AT (1) | ATE326227T1 (zh) |
AU (2) | AU5003401A (zh) |
BG (1) | BG66075B1 (zh) |
BR (1) | BR0109334A (zh) |
CA (1) | CA2402983A1 (zh) |
CY (1) | CY1105632T1 (zh) |
CZ (1) | CZ20023162A3 (zh) |
DE (1) | DE60119703T2 (zh) |
DK (1) | DK1265616T3 (zh) |
EA (1) | EA005592B1 (zh) |
EE (1) | EE05129B1 (zh) |
ES (1) | ES2261393T3 (zh) |
HK (1) | HK1049449B (zh) |
HR (1) | HRP20020837B1 (zh) |
HU (1) | HUP0302093A3 (zh) |
IL (1) | IL151512A0 (zh) |
MX (1) | MXPA02009116A (zh) |
NO (1) | NO326886B1 (zh) |
NZ (1) | NZ521171A (zh) |
PL (1) | PL201762B1 (zh) |
PT (1) | PT1265616E (zh) |
SK (1) | SK286169B6 (zh) |
TW (1) | TWI271194B (zh) |
WO (1) | WO2001070208A2 (zh) |
Families Citing this family (51)
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US20010044431A1 (en) * | 2000-03-21 | 2001-11-22 | Rodriguez Gustavo C. | Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium |
US6245819B1 (en) | 2000-07-21 | 2001-06-12 | Hormos Medical Oy, Ltd. | Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause |
NZ528373A (en) * | 2001-03-16 | 2005-07-29 | Wyeth Corp | Hormone replacement therapy |
EP1857110A3 (en) * | 2001-03-16 | 2008-08-06 | Wyeth | Hormone replacement therapy |
US20130203722A1 (en) | 2006-09-26 | 2013-08-08 | Rhonda R. Voskuhl | Estriol therapy for autoimmune and neurodegenerative disease and disorders |
WO2008150547A1 (en) | 2007-06-04 | 2008-12-11 | The Regents Of The University Of California | Pregnancy hormone combination for treatment of autoimmune diseases |
TWI252111B (en) * | 2001-12-14 | 2006-04-01 | Solvay Pharm Gmbh | Matrix film tablet with controlled release of a natural mixture of conjugated estrogens |
AU2003210759B2 (en) * | 2002-04-03 | 2007-01-25 | Barr Laboratories, Inc. | Step-down estrogen therapy |
TW200306196A (en) * | 2002-04-03 | 2003-11-16 | Wyeth Corp | Hormone replacement therapy |
TW200306846A (en) * | 2002-04-03 | 2003-12-01 | Wyeth Corp | Hormone replacement therapy |
TW200306851A (en) * | 2002-04-29 | 2003-12-01 | Wyeth Corp | Hormone replacement therapy |
TW200400040A (en) * | 2002-05-17 | 2004-01-01 | Wyeth Corp | Hormone replacement therapy |
PL214242B1 (pl) * | 2002-06-06 | 2013-07-31 | Hormos Medical Corp | Zastosowanie ospemifenu, jego soli lub metabolitu do wytwarzania kompozycji farmaceutycznej do leczenia lub zapobiegania objawom zwiazanym z atrofia narzadów moczowo-plciowych u kobiet podczas lub po menopauzie |
WO2004000225A2 (en) * | 2002-06-25 | 2003-12-31 | Wyeth | Use of thio-oxindole derivatives in treatment of hormone-related conditions |
CN1662241A (zh) * | 2002-06-25 | 2005-08-31 | 惠氏公司 | 环硫代氨基甲酸酯衍生物在治疗与激素有关的病症中的用途 |
US8349819B2 (en) | 2002-10-09 | 2013-01-08 | Dr. Reddy's Laboratories New York, Inc. | Steroid extraction process from urine sources |
US20040259851A1 (en) * | 2003-04-11 | 2004-12-23 | Leonard Thomas W. | Methods of administering estrogens and progestins |
US20060040904A1 (en) * | 2004-08-17 | 2006-02-23 | Ahmed Salah U | Vaginal cream compositions, kits thereof and methods of using thereof |
WO2007076144A2 (en) | 2005-12-27 | 2007-07-05 | Duramed Pharmaceuticals, Inc. | Conjugated estrogen compositions, applicators, kits, and methods of making and use thereof |
AU2007234841A1 (en) * | 2006-04-05 | 2007-10-18 | Wyeth | Methods for prevention and treatment of conditions arising from local estrogen deficiency |
TW200831139A (en) * | 2006-11-29 | 2008-08-01 | Wyeth Corp | Estrogen/SERM and estrogen/progestin bi-layer tablets |
US7504530B2 (en) * | 2007-02-14 | 2009-03-17 | Hormos Medical Ltd. | Methods for the preparation of fispemifene from ospemifene |
KR101510646B1 (ko) * | 2007-02-14 | 2015-04-10 | 호르모스 메디칼 리미티드 | 치료적으로 유용한 트리페닐부텐 유도체의 제조 방법 |
KR100989093B1 (ko) | 2008-01-18 | 2010-10-25 | 한화제약주식회사 | 생강나무 가지의 추출물을 포함하는 심혈관계 질환의 예방 및 치료용 조성물 |
US9734496B2 (en) | 2009-05-29 | 2017-08-15 | Paypal, Inc. | Trusted remote attestation agent (TRAA) |
US10231976B2 (en) * | 2010-02-08 | 2019-03-19 | Prairie Pharmaceuticals LLC | Methods for the use of progestogen as a glucocorticoid sensitizer |
JP6285866B2 (ja) | 2011-11-23 | 2018-02-28 | セラピューティックスエムディー インコーポレーテッドTherapeuticsmd, Inc. | 天然複合ホルモン補充製剤および療法 |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
US9321712B2 (en) | 2012-10-19 | 2016-04-26 | Fermion Oy | Process for the preparation of ospemifene |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
WO2015089489A1 (en) * | 2013-12-13 | 2015-06-18 | Requis Pharmaceuticals Inc. | Antihistamines in combination with a range of substance for improved health |
ES2959603T3 (es) | 2014-04-28 | 2024-02-27 | Univ California | Envase farmacéutico para terapia con estriol para el tratamiento de la esclerosis múltiple |
US10799512B2 (en) | 2014-04-28 | 2020-10-13 | The Regents Of The University Of California | Estrogen combination for treatment of multiple sclerosis |
AU2015264003A1 (en) | 2014-05-22 | 2016-11-17 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
WO2016036719A1 (en) | 2014-09-02 | 2016-03-10 | The Regents Of The University Of California | Estrogen therapy for brain gray matter atrophy and associated disability |
ES2957543T3 (es) | 2014-09-29 | 2024-01-22 | Univ California | Composiciones y métodos para mantener la función cognitiva |
WO2016160832A1 (en) | 2015-03-30 | 2016-10-06 | The Regents Of The University Of California | Methods of monitoring estriol therapy |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
EP3435977A4 (en) | 2016-04-01 | 2019-10-16 | Therapeuticsmd, Inc. | PHARMACEUTICAL COMPOSITION OF STEROID HORMONE |
US20210386757A1 (en) * | 2018-10-17 | 2021-12-16 | Sarah S. Stadler | Methods of Treating Menopausal Symptoms Using Low Dose Progesterone |
US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
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Publication number | Priority date | Publication date | Assignee | Title |
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US4826831A (en) * | 1983-08-05 | 1989-05-02 | Pre Jay Holdings Limited | Method of hormonal treatment for menopausal or post-menopausal disorders involving continuous administration of progestogens and estrogens |
AU582540B2 (en) * | 1983-08-05 | 1989-04-06 | Pre Jay Holdings Ltd. | A method of hormonal treatment of perimenopausal, menopausal and post-menopausal disorders and multi-preparation pack therefor |
ATE209919T1 (de) * | 1987-09-24 | 2001-12-15 | Jencap Res Ltd | Oestrogen und progestin enthaltende verhütungspackungen |
NL9301562A (nl) * | 1993-09-09 | 1995-04-03 | Saturnus Ag | Preparaat voor substitutietherapie. |
US5554601A (en) * | 1993-11-05 | 1996-09-10 | University Of Florida | Methods for neuroprotection |
US5547948A (en) * | 1995-01-17 | 1996-08-20 | American Home Products Corporation | Controlled release of steroids from sugar coatings |
US5759577A (en) * | 1995-01-17 | 1998-06-02 | American Home Products Corporation | Controlled release of steroids from sugar coatings |
-
2001
- 2001-03-15 US US09/808,878 patent/US20010034340A1/en not_active Abandoned
- 2001-03-16 CZ CZ20023162A patent/CZ20023162A3/cs unknown
- 2001-03-16 HU HU0302093A patent/HUP0302093A3/hu unknown
- 2001-03-16 PL PL363157A patent/PL201762B1/pl not_active IP Right Cessation
- 2001-03-16 AU AU5003401A patent/AU5003401A/xx active Pending
- 2001-03-16 AU AU2001250034A patent/AU2001250034B2/en not_active Ceased
- 2001-03-16 DK DK01923331T patent/DK1265616T3/da active
- 2001-03-16 WO PCT/US2001/040302 patent/WO2001070208A2/en active IP Right Grant
- 2001-03-16 SK SK1348-2002A patent/SK286169B6/sk not_active IP Right Cessation
- 2001-03-16 CN CNB018068235A patent/CN1239160C/zh not_active Expired - Fee Related
- 2001-03-16 CA CA002402983A patent/CA2402983A1/en not_active Abandoned
- 2001-03-16 AT AT01923331T patent/ATE326227T1/de active
- 2001-03-16 IL IL15151201A patent/IL151512A0/xx not_active IP Right Cessation
- 2001-03-16 MX MXPA02009116A patent/MXPA02009116A/es active IP Right Grant
- 2001-03-16 ES ES01923331T patent/ES2261393T3/es not_active Expired - Lifetime
- 2001-03-16 EP EP01923331A patent/EP1265616B1/en not_active Expired - Lifetime
- 2001-03-16 EE EEP200200535A patent/EE05129B1/xx not_active IP Right Cessation
- 2001-03-16 DE DE60119703T patent/DE60119703T2/de not_active Expired - Lifetime
- 2001-03-16 EA EA200201000A patent/EA005592B1/ru not_active IP Right Cessation
- 2001-03-16 PT PT01923331T patent/PT1265616E/pt unknown
- 2001-03-16 NZ NZ521171A patent/NZ521171A/en not_active IP Right Cessation
- 2001-03-16 JP JP2001568406A patent/JP2003527416A/ja active Pending
- 2001-03-16 BR BR0109334-7A patent/BR0109334A/pt not_active Application Discontinuation
- 2001-03-16 KR KR1020027012420A patent/KR100805648B1/ko not_active IP Right Cessation
- 2001-03-19 AR ARP010101273A patent/AR031563A1/es unknown
- 2001-03-19 TW TW090106349A patent/TWI271194B/zh not_active IP Right Cessation
-
2002
- 2002-09-12 BG BG107095A patent/BG66075B1/xx unknown
- 2002-09-19 NO NO20024478A patent/NO326886B1/no not_active IP Right Cessation
- 2002-10-18 HR HR20020837A patent/HRP20020837B1/xx not_active IP Right Cessation
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2003
- 2003-03-06 HK HK03101651.5A patent/HK1049449B/zh not_active IP Right Cessation
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2006
- 2006-07-03 CY CY20061100910T patent/CY1105632T1/el unknown
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2007
- 2007-11-06 US US11/979,633 patent/US20090005351A1/en not_active Abandoned
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PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20120316 |