HK1049171A1 - Selective n-acylation of a82846 glycopeptide analogs - Google Patents

Selective n-acylation of a82846 glycopeptide analogs

Info

Publication number
HK1049171A1
HK1049171A1 HK03100030A HK03100030A HK1049171A1 HK 1049171 A1 HK1049171 A1 HK 1049171A1 HK 03100030 A HK03100030 A HK 03100030A HK 03100030 A HK03100030 A HK 03100030A HK 1049171 A1 HK1049171 A1 HK 1049171A1
Authority
HK
Hong Kong
Prior art keywords
acylation
selective
glycopeptide
glycopeptide analogs
analogs
Prior art date
Application number
HK03100030A
Other languages
English (en)
Inventor
Richard Craig Thompson
Stephen Charles Wilkie
Mark James Zweifel
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HK1049171A1 publication Critical patent/HK1049171A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
HK03100030A 2000-02-11 2003-01-02 Selective n-acylation of a82846 glycopeptide analogs HK1049171A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18168300P 2000-02-11 2000-02-11
PCT/US2001/004540 WO2001058933A2 (en) 2000-02-11 2001-02-12 Selective n-acylation of a82846 glycopeptide analogs

Publications (1)

Publication Number Publication Date
HK1049171A1 true HK1049171A1 (en) 2003-05-02

Family

ID=22665319

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03100030A HK1049171A1 (en) 2000-02-11 2003-01-02 Selective n-acylation of a82846 glycopeptide analogs

Country Status (18)

Country Link
US (1) US7365053B2 (ko)
EP (1) EP1254164B1 (ko)
JP (1) JP2003522197A (ko)
KR (1) KR100796079B1 (ko)
CN (1) CN1422279A (ko)
AT (1) ATE308560T1 (ko)
AU (2) AU3818001A (ko)
BR (1) BR0108268A (ko)
CA (1) CA2399640A1 (ko)
CZ (1) CZ20022722A3 (ko)
DE (1) DE60114567T2 (ko)
HK (1) HK1049171A1 (ko)
MX (1) MXPA02007739A (ko)
NO (1) NO20023761L (ko)
NZ (1) NZ520482A (ko)
PL (1) PL356966A1 (ko)
WO (1) WO2001058933A2 (ko)
ZA (1) ZA200206360B (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060091049A (ko) * 2002-08-30 2006-08-17 케이.유.루벤 리서치 앤드 디벨럽먼트 글리코펩티드 항생제 및 그것의 반합성 유도체 및 항바이러스제로서의 그것의 사용
US8088387B2 (en) * 2003-10-10 2012-01-03 Immunogen Inc. Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
CN1557479A (zh) * 2004-01-16 2004-12-29 深圳市海王英特龙生物技术股份有限公 干扰素脂质体乳膏
US7632918B2 (en) 2005-02-28 2009-12-15 Novartis Vaccines And Diagnostics, Inc. Semi-synthetic glycopeptides with antibiotic activity
US20200368312A1 (en) 2017-05-22 2020-11-26 Insmed Incorporated Glycopeptide derivative compounds and uses thereof
CN108484719A (zh) * 2018-01-19 2018-09-04 四川大学 硫酸酯化十二指肠糖肽制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4698327A (en) * 1985-04-25 1987-10-06 Eli Lilly And Company Novel glycopeptide derivatives
US4643987A (en) * 1985-08-14 1987-02-17 Eli Lilly And Company Modified glycopeptides
US4639433A (en) * 1985-08-14 1987-01-27 Eli Lilly And Company Glycopeptide derivatives
ZA909847B (en) * 1989-12-13 1992-08-26 Lilly Co Eli Glycopeptide derivatives
US5840684A (en) * 1994-01-28 1998-11-24 Eli Lilly And Company Glycopeptide antibiotic derivatives
DK1073447T3 (da) 1998-05-01 2007-09-03 Lilly Co Eli N1-modificerede glycopeptider

Also Published As

Publication number Publication date
NO20023761D0 (no) 2002-08-08
AU3818001A (en) 2001-08-20
JP2003522197A (ja) 2003-07-22
DE60114567T2 (de) 2006-07-27
WO2001058933A2 (en) 2001-08-16
US20070219123A1 (en) 2007-09-20
KR100796079B1 (ko) 2008-01-21
AU2001238180B2 (en) 2005-12-15
CN1422279A (zh) 2003-06-04
ATE308560T1 (de) 2005-11-15
CA2399640A1 (en) 2001-08-16
EP1254164A2 (en) 2002-11-06
BR0108268A (pt) 2003-03-05
DE60114567D1 (de) 2005-12-08
EP1254164B1 (en) 2005-11-02
CZ20022722A3 (cs) 2003-01-15
ZA200206360B (en) 2003-11-10
AU2001238180B8 (en) 2006-07-27
PL356966A1 (en) 2004-07-12
WO2001058933A3 (en) 2002-02-14
NO20023761L (no) 2002-08-26
KR20020073546A (ko) 2002-09-26
US7365053B2 (en) 2008-04-29
NZ520482A (en) 2004-12-24
MXPA02007739A (es) 2002-10-11

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20110212