PL356966A1 - Selective n-acylation of a82846 glycopeptide analogs - Google Patents

Selective n-acylation of a82846 glycopeptide analogs

Info

Publication number
PL356966A1
PL356966A1 PL01356966A PL35696601A PL356966A1 PL 356966 A1 PL356966 A1 PL 356966A1 PL 01356966 A PL01356966 A PL 01356966A PL 35696601 A PL35696601 A PL 35696601A PL 356966 A1 PL356966 A1 PL 356966A1
Authority
PL
Poland
Prior art keywords
acylation
selective
glycopeptide
glycopeptide analogs
analogs
Prior art date
Application number
PL01356966A
Other languages
Polish (pl)
Inventor
Richard Craig Thompson
Stephen Charles Wilkie
Mark James Zweifel
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of PL356966A1 publication Critical patent/PL356966A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The present invention provides a process for selectively acylating an A82846A, A82846B, A82846C or PA-42867-A glycopeptide at the N1, N2 or N3 positions and the monoacylated compounds prepared therefrom.
PL01356966A 2000-02-11 2001-02-12 Selective n-acylation of a82846 glycopeptide analogs PL356966A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18168300P 2000-02-11 2000-02-11
PCT/US2001/004540 WO2001058933A2 (en) 2000-02-11 2001-02-12 Selective n-acylation of a82846 glycopeptide analogs

Publications (1)

Publication Number Publication Date
PL356966A1 true PL356966A1 (en) 2004-07-12

Family

ID=22665319

Family Applications (1)

Application Number Title Priority Date Filing Date
PL01356966A PL356966A1 (en) 2000-02-11 2001-02-12 Selective n-acylation of a82846 glycopeptide analogs

Country Status (18)

Country Link
US (1) US7365053B2 (en)
EP (1) EP1254164B1 (en)
JP (1) JP2003522197A (en)
KR (1) KR100796079B1 (en)
CN (1) CN1422279A (en)
AT (1) ATE308560T1 (en)
AU (2) AU2001238180B8 (en)
BR (1) BR0108268A (en)
CA (1) CA2399640A1 (en)
CZ (1) CZ20022722A3 (en)
DE (1) DE60114567T2 (en)
HK (1) HK1049171A1 (en)
MX (1) MXPA02007739A (en)
NO (1) NO20023761L (en)
NZ (1) NZ520482A (en)
PL (1) PL356966A1 (en)
WO (1) WO2001058933A2 (en)
ZA (1) ZA200206360B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003260198A1 (en) * 2002-08-30 2004-03-19 Chiron Corporation Glycopeptide antibiotic and semisynthetic derivatives thereof and their use as antiviral agents
US8088387B2 (en) * 2003-10-10 2012-01-03 Immunogen Inc. Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
CN1557479A (en) * 2004-01-16 2004-12-29 深圳市海王英特龙生物技术股份有限公 Interferon liposome emulsifiable paste
US7632918B2 (en) 2005-02-28 2009-12-15 Novartis Vaccines And Diagnostics, Inc. Semi-synthetic glycopeptides with antibiotic activity
GB2577419B (en) 2017-05-22 2022-08-17 Insmed Inc Lipo-glycopeptide cleavable derivatives and uses thereof
CN108484719A (en) * 2018-01-19 2018-09-04 四川大学 Sulfation duodenum glycopeptide preparation method

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4698327A (en) * 1985-04-25 1987-10-06 Eli Lilly And Company Novel glycopeptide derivatives
US4643987A (en) * 1985-08-14 1987-02-17 Eli Lilly And Company Modified glycopeptides
US4639433A (en) * 1985-08-14 1987-01-27 Eli Lilly And Company Glycopeptide derivatives
CA2031803C (en) * 1989-12-13 2001-05-29 Ramakrishnan Nagarajan Improvements in or relating to glycopeptide deriveratives
US5840684A (en) * 1994-01-28 1998-11-24 Eli Lilly And Company Glycopeptide antibiotic derivatives
ES2283107T3 (en) * 1998-05-01 2007-10-16 Eli Lilly And Company MODIFIED GLICOPEPTIDES IN N1.

Also Published As

Publication number Publication date
US20070219123A1 (en) 2007-09-20
WO2001058933A3 (en) 2002-02-14
NO20023761L (en) 2002-08-26
EP1254164B1 (en) 2005-11-02
DE60114567T2 (en) 2006-07-27
AU3818001A (en) 2001-08-20
NO20023761D0 (en) 2002-08-08
US7365053B2 (en) 2008-04-29
CZ20022722A3 (en) 2003-01-15
CA2399640A1 (en) 2001-08-16
JP2003522197A (en) 2003-07-22
KR20020073546A (en) 2002-09-26
MXPA02007739A (en) 2002-10-11
BR0108268A (en) 2003-03-05
DE60114567D1 (en) 2005-12-08
WO2001058933A2 (en) 2001-08-16
NZ520482A (en) 2004-12-24
ZA200206360B (en) 2003-11-10
AU2001238180B2 (en) 2005-12-15
CN1422279A (en) 2003-06-04
EP1254164A2 (en) 2002-11-06
ATE308560T1 (en) 2005-11-15
AU2001238180B8 (en) 2006-07-27
HK1049171A1 (en) 2003-05-02
KR100796079B1 (en) 2008-01-21

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Legal Events

Date Code Title Description
REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)