HK1047769B - 病毒基因表達的調節 - Google Patents
病毒基因表達的調節Info
- Publication number
- HK1047769B HK1047769B HK02109393.2A HK02109393A HK1047769B HK 1047769 B HK1047769 B HK 1047769B HK 02109393 A HK02109393 A HK 02109393A HK 1047769 B HK1047769 B HK 1047769B
- Authority
- HK
- Hong Kong
- Prior art keywords
- regulation
- gene expression
- viral gene
- viral
- expression
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8283—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for virus resistance
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/309,038 US7019195B1 (en) | 1998-05-26 | 1999-05-10 | Method for conferring resistance or tolerance aganist furovirus, potyvirus, tospovirus, and cucomovirus to plant cells |
PCT/EP2000/004117 WO2000068374A1 (en) | 1999-05-10 | 2000-05-08 | Regulation of viral gene expression |
Publications (2)
Publication Number | Publication Date |
---|---|
HK1047769A1 HK1047769A1 (en) | 2003-03-07 |
HK1047769B true HK1047769B (zh) | 2009-08-14 |
Family
ID=23196412
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK02105312.8A HK1045325A1 (zh) | 1999-05-10 | 2002-07-17 | 病毒基因表達的調節方法 |
HK02109393.2A HK1047769B (zh) | 1999-05-10 | 2002-12-30 | 病毒基因表達的調節 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK02105312.8A HK1045325A1 (zh) | 1999-05-10 | 2002-07-17 | 病毒基因表達的調節方法 |
Country Status (18)
Country | Link |
---|---|
EP (2) | EP1801215B1 (zh) |
JP (3) | JP2002543783A (zh) |
KR (1) | KR20010112952A (zh) |
CN (2) | CN101348785A (zh) |
AR (1) | AR023885A1 (zh) |
AU (1) | AU4563300A (zh) |
BR (1) | BR0010496A (zh) |
CA (1) | CA2369422A1 (zh) |
CZ (1) | CZ20014028A3 (zh) |
EA (1) | EA200101186A1 (zh) |
HK (2) | HK1045325A1 (zh) |
HU (1) | HUP0201235A3 (zh) |
IL (2) | IL145538A0 (zh) |
PL (1) | PL351385A1 (zh) |
SK (1) | SK16222001A3 (zh) |
TR (1) | TR200103088T2 (zh) |
WO (1) | WO2000068374A1 (zh) |
ZA (1) | ZA200109152B (zh) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19956568A1 (de) | 1999-01-30 | 2000-08-17 | Roland Kreutzer | Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens |
EP1206558B1 (en) | 1999-08-26 | 2008-01-09 | Calgene LLC | Plants with modified polyunsaturated fatty acids |
US7067722B2 (en) | 1999-08-26 | 2006-06-27 | Monsanto Technology Llc | Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids |
US7531718B2 (en) | 1999-08-26 | 2009-05-12 | Monsanto Technology, L.L.C. | Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids |
DE10100586C1 (de) | 2001-01-09 | 2002-04-11 | Ribopharma Ag | Verfahren zur Hemmung der Expression eines Ziegens |
CH695778A5 (de) * | 2000-11-29 | 2006-08-31 | Hoffmann La Roche | Hemmung der Transkription eines Zielgens in einer Zelle oder in Geweben. |
US8546143B2 (en) | 2001-01-09 | 2013-10-01 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of a target gene |
US7423142B2 (en) | 2001-01-09 | 2008-09-09 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of anti-apoptotic genes |
US7767802B2 (en) | 2001-01-09 | 2010-08-03 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of anti-apoptotic genes |
US8022272B2 (en) | 2001-07-13 | 2011-09-20 | Sungene Gmbh & Co. Kgaa | Expression cassettes for transgenic expression of nucleic acids |
US7456335B2 (en) | 2001-09-03 | 2008-11-25 | Basf Plant Science Gmbh | Nucleic acid sequences and their use in methods for achieving pathogen resistance in plants |
DE10163098B4 (de) | 2001-10-12 | 2005-06-02 | Alnylam Europe Ag | Verfahren zur Hemmung der Replikation von Viren |
US7745418B2 (en) | 2001-10-12 | 2010-06-29 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting viral replication |
DE10202419A1 (de) | 2002-01-22 | 2003-08-07 | Ribopharma Ag | Verfahren zur Hemmung der Expression eines durch eine Chromosomen-Aberration entstandenen Zielgens |
US7166771B2 (en) | 2002-06-21 | 2007-01-23 | Monsanto Technology Llc | Coordinated decrease and increase of gene expression of more than one gene using transgenic constructs |
US7566813B2 (en) | 2002-03-21 | 2009-07-28 | Monsanto Technology, L.L.C. | Nucleic acid constructs and methods for producing altered seed oil compositions |
EP2294915A3 (en) | 2002-03-21 | 2011-04-13 | Monsanto Technology LLC | Nucleic acid constructs and methods for producing altered seed oil compositions |
ATE405658T1 (de) | 2002-07-26 | 2008-09-15 | Basf Plant Science Gmbh | Neue selektionsverfahren |
CA2494626A1 (en) | 2002-08-07 | 2004-03-04 | Basf Plant Science Gmbh | Nucleic acid sequences encoding proteins associated with abiotic stress response |
WO2006032707A2 (en) | 2004-09-24 | 2006-03-30 | Basf Plant Science Gmbh | Plant cells and plants with increased tolerance to environmental stress |
WO2005014828A2 (en) | 2003-08-01 | 2005-02-17 | Basf Plant Science Gmbh | Process for the production of fine chemicals in plants |
EP2080769A3 (en) | 2004-07-02 | 2010-12-01 | Metanomics GmbH | Process for the production of fine chemicals |
EP2166103B1 (en) | 2004-08-02 | 2013-05-22 | BASF Plant Science GmbH | Method for isolation of transcription termination sequences |
EP2163632A1 (en) | 2004-10-05 | 2010-03-17 | SunGene GmbH | Constitutive expression cassettes for regulation of plant expression |
ES2444001T3 (es) * | 2004-10-21 | 2014-02-21 | Venganza Inc. | Procedimientos y materiales para conferir resistencia a plagas y patógenos de plantas |
EP1655364A3 (en) | 2004-11-05 | 2006-08-02 | BASF Plant Science GmbH | Expression cassettes for seed-preferential expression in plants |
EP2163631B1 (en) | 2004-11-25 | 2013-05-22 | SunGene GmbH | Expression cassettes for guard cell-preferential expression in plants |
EP1666599A3 (en) | 2004-12-04 | 2006-07-12 | SunGene GmbH | Expression cassettes for mesophyll- and/or epidermis-preferential expression in plants |
EP2072620B1 (en) | 2004-12-08 | 2013-05-08 | SunGene GmbH | Expression casstettes for vascular tissue-preferential expression in plants |
EP1669456A3 (en) | 2004-12-11 | 2006-07-12 | SunGene GmbH | Expression cassettes for meristem-preferential expression in plants |
EP2199304A1 (en) | 2004-12-17 | 2010-06-23 | Metanomics GmbH | Process for the control of production of fine chemicals |
CA2596600A1 (en) | 2005-02-09 | 2006-08-17 | Basf Plant Science Gmbh | Expression cassettes for regulation of expression in monocotyledonous plants |
WO2006089950A2 (en) | 2005-02-26 | 2006-08-31 | Basf Plant Science Gmbh | Expression cassettes for seed-preferential expression in plants |
EP1859037A2 (en) | 2005-03-08 | 2007-11-28 | BASF Plant Science GmbH | Expression enhancing intron sequences |
AU2006245701B2 (en) | 2005-05-10 | 2011-04-28 | Basf Plant Science Gmbh | Expression cassettes for seed-preferential expression in plants |
WO2006128572A1 (en) * | 2005-06-02 | 2006-12-07 | Syngenta Participations Ag | Ce46-02a insecticidal cotton |
US7994399B2 (en) | 2005-06-23 | 2011-08-09 | Basf Plant Science Gmbh | Methods for the production of stably transformed, fertile Zea mays plants |
EP2980220A1 (en) | 2005-09-20 | 2016-02-03 | BASF Plant Science GmbH | Improved methods controlling gene expression |
EP1948806A2 (de) | 2005-11-08 | 2008-07-30 | BASF Plant Science GmbH | Verwendung von armadillo-repeat (arm1)-polynukleotiden zum erreichen einer pathogenresistenz in pflanzen |
US8178751B2 (en) | 2006-01-12 | 2012-05-15 | Basf Plant Science Gmbh | Use of stomatin (STM1) polynucleotides for achieving a pathogen resistance in plants |
CN101421406B (zh) | 2006-02-13 | 2016-08-31 | 孟山都技术有限公司 | 用于产生改变的种子油组成的核酸构建体和方法 |
AU2007299219A1 (en) | 2006-04-05 | 2008-03-27 | Metanomics Gmbh | Process for the production of a fine chemical |
KR100809736B1 (ko) | 2006-05-15 | 2008-03-05 | 대한민국 | 안토시아닌 생합성 억제 활성을 가진 myb60 유전자와상기 유전자가 도입된 형질전환 상추 및 그 제조방법 |
EP2121921A4 (en) * | 2006-12-13 | 2010-08-04 | Idiverse Inc | NEW, STRESSTOLERANZ TRANSMITTING GENES AND RNA MOLECULES |
US8592652B2 (en) | 2007-01-15 | 2013-11-26 | Basf Plant Science Gmbh | Use of subtilisin-like RNR9 polynucleotide for achieving pathogen resistance in plants |
AU2008214568B2 (en) | 2007-02-16 | 2013-04-18 | Basf Plant Science Gmbh | Nucleic acid sequences for regulation of embryo-specific expression in monocotyledonous plants |
AU2008252998A1 (en) | 2007-05-22 | 2008-11-27 | Basf Plant Science Gmbh | Plant cells and plants with increased tolerance and/or resistance to environmental stress and increased biomass production-KO |
EP2240587A2 (en) | 2007-12-21 | 2010-10-20 | BASF Plant Science GmbH | Plants with increased yield (ko nue) |
AR075549A1 (es) | 2008-09-29 | 2011-04-20 | Monsanto Technology Llc | Evento transgenico de soja mon87705 y metodos para detectar el mismo |
EP2208785A1 (en) * | 2009-01-15 | 2010-07-21 | Newbiotechnic, S.A. | Methods and kits to generate miRNA- and smallRNA-expressing vectors, and its application to develop lentiviral expression libraries |
CA2756146C (en) | 2009-04-22 | 2018-12-04 | Basf Plant Science Company Gmbh | Whole seed specific promoter |
AU2010270309A1 (en) | 2009-07-10 | 2012-02-02 | Basf Plant Science Company Gmbh | Expression cassettes for endosperm-specific expression in plants |
DE112010005958T5 (de) | 2009-12-03 | 2013-08-14 | Basf Plant Science Company Gmbh | Expressionskassetten für die Embryo-spezifische Expression in Pflanzen |
WO2012008768A2 (ko) * | 2010-07-14 | 2012-01-19 | 대한민국(농촌진흥청장) | 다종 바이러스 저항성을 갖는 형질전환 감자 식물체의 제조방법 및 이를 이용하여 제조된 감자 식물체 |
CN103667322B (zh) * | 2013-11-21 | 2015-11-11 | 上海市农业科学院 | 一种抗番茄黄化曲叶病毒的多基因嵌合体avctc及其制备方法和应用 |
AP2016009478A0 (en) * | 2014-03-12 | 2016-09-30 | Univ Sydney | Rna production in higher plants |
CA3067988A1 (en) * | 2017-05-22 | 2018-11-29 | Pebble Labs Usa Inc. | Transbiotic regulation of bacterial gene expression |
CN116004714B (zh) * | 2022-07-27 | 2024-09-10 | 武汉大学 | 基于Spacer基因定向插入TC-Tag标签的细胞系、重组病毒及其制备方法与应用 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04507083A (ja) * | 1989-05-19 | 1992-12-10 | ヘム・リサーチ・インコーポレーテッド | 規定された構造の短い治療用dsRNA |
ES2079647T5 (es) * | 1990-03-02 | 2009-01-16 | Bayer Bioscience N.V. | Transformacion genetica y regeneracion de la remolacha azucarera. |
GB9320548D0 (en) * | 1993-10-06 | 1993-11-24 | Sandoz Ltd | Improvements in or relating to organic compounds |
GB9703146D0 (en) * | 1997-02-14 | 1997-04-02 | Innes John Centre Innov Ltd | Methods and means for gene silencing in transgenic plants |
CN1252102A (zh) * | 1997-02-19 | 2000-05-03 | 康乃尔研究基金会有限公司 | 能赋予植物多种性状的dna构建体 |
GB9710475D0 (en) * | 1997-05-21 | 1997-07-16 | Zeneca Ltd | Gene silencing |
GB9720148D0 (en) * | 1997-09-22 | 1997-11-26 | Innes John Centre Innov Ltd | Gene silencing materials and methods |
US6506559B1 (en) * | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
JP4187413B2 (ja) * | 1998-03-20 | 2008-11-26 | コモンウェルス サイエンティフィック アンドインダストリアル リサーチ オーガナイゼーション | 遺伝子発現の制御 |
PT1068311E (pt) * | 1998-04-08 | 2011-07-20 | Commw Scient Ind Res Org | Processos e meios de obter fenótipos modificados |
AR020078A1 (es) * | 1998-05-26 | 2002-04-10 | Syngenta Participations Ag | Metodo para alterar la expresion de un gen objetivo en una celula de planta |
WO2000044914A1 (en) * | 1999-01-28 | 2000-08-03 | Medical College Of Georgia Research Institute, Inc. | Composition and method for in vivo and in vitro attenuation of gene expression using double stranded rna |
-
2000
- 2000-05-08 CA CA002369422A patent/CA2369422A1/en not_active Abandoned
- 2000-05-08 CN CNA2008102106166A patent/CN101348785A/zh active Pending
- 2000-05-08 CN CNB008073597A patent/CN100420748C/zh not_active Expired - Fee Related
- 2000-05-08 EA EA200101186A patent/EA200101186A1/ru unknown
- 2000-05-08 IL IL14553800A patent/IL145538A0/xx unknown
- 2000-05-08 AR ARP000102213A patent/AR023885A1/es not_active Application Discontinuation
- 2000-05-08 AU AU45633/00A patent/AU4563300A/en not_active Abandoned
- 2000-05-08 JP JP2000616341A patent/JP2002543783A/ja not_active Withdrawn
- 2000-05-08 HU HU0201235A patent/HUP0201235A3/hu unknown
- 2000-05-08 PL PL00351385A patent/PL351385A1/xx not_active IP Right Cessation
- 2000-05-08 EP EP06026160A patent/EP1801215B1/en not_active Expired - Lifetime
- 2000-05-08 WO PCT/EP2000/004117 patent/WO2000068374A1/en not_active Application Discontinuation
- 2000-05-08 EP EP00927165A patent/EP1177283A1/en not_active Withdrawn
- 2000-05-08 BR BR0010496-5A patent/BR0010496A/pt not_active Application Discontinuation
- 2000-05-08 KR KR1020017014335A patent/KR20010112952A/ko not_active Application Discontinuation
- 2000-05-08 TR TR2001/03088T patent/TR200103088T2/xx unknown
- 2000-05-08 CZ CZ20014028A patent/CZ20014028A3/cs unknown
- 2000-05-08 SK SK1622-2001A patent/SK16222001A3/sk unknown
-
2001
- 2001-09-21 IL IL145538A patent/IL145538A/en not_active IP Right Cessation
- 2001-11-06 ZA ZA200109152A patent/ZA200109152B/en unknown
-
2002
- 2002-07-17 HK HK02105312.8A patent/HK1045325A1/zh unknown
- 2002-12-30 HK HK02109393.2A patent/HK1047769B/zh not_active IP Right Cessation
-
2008
- 2008-09-02 JP JP2008224753A patent/JP2009022291A/ja not_active Withdrawn
-
2009
- 2009-11-06 JP JP2009255087A patent/JP2010088435A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
BR0010496A (pt) | 2002-04-02 |
IL145538A (en) | 2010-11-30 |
CN101348785A (zh) | 2009-01-21 |
EP1801215A2 (en) | 2007-06-27 |
CN1357040A (zh) | 2002-07-03 |
JP2002543783A (ja) | 2002-12-24 |
HUP0201235A2 (en) | 2002-08-28 |
IL145538A0 (en) | 2002-06-30 |
HK1045325A1 (zh) | 2002-11-22 |
AR023885A1 (es) | 2002-09-04 |
CN100420748C (zh) | 2008-09-24 |
TR200103088T2 (tr) | 2002-05-21 |
KR20010112952A (ko) | 2001-12-22 |
HK1047769A1 (en) | 2003-03-07 |
AU4563300A (en) | 2000-11-21 |
CZ20014028A3 (cs) | 2002-02-13 |
JP2010088435A (ja) | 2010-04-22 |
JP2009022291A (ja) | 2009-02-05 |
HUP0201235A3 (en) | 2004-10-28 |
EP1177283A1 (en) | 2002-02-06 |
EA200101186A1 (ru) | 2002-04-25 |
CA2369422A1 (en) | 2000-11-16 |
ZA200109152B (en) | 2002-09-06 |
PL351385A1 (en) | 2003-04-07 |
WO2000068374A1 (en) | 2000-11-16 |
EP1801215B1 (en) | 2013-02-27 |
SK16222001A3 (sk) | 2002-04-04 |
EP1801215A3 (en) | 2008-12-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20140508 |