HK1045498B - 純化雙醋瑞因的方法 - Google Patents

純化雙醋瑞因的方法

Info

Publication number
HK1045498B
HK1045498B HK02107045.8A HK02107045A HK1045498B HK 1045498 B HK1045498 B HK 1045498B HK 02107045 A HK02107045 A HK 02107045A HK 1045498 B HK1045498 B HK 1045498B
Authority
HK
Hong Kong
Prior art keywords
diacerein
purification
Prior art date
Application number
HK02107045.8A
Other languages
English (en)
Other versions
HK1045498A1 (en
Inventor
M‧希尼斯特裡
R‧希尼斯特裡
Original Assignee
辛特克股份公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 辛特克股份公司 filed Critical 辛特克股份公司
Publication of HK1045498A1 publication Critical patent/HK1045498A1/xx
Publication of HK1045498B publication Critical patent/HK1045498B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/48—Separation; Purification; Stabilisation; Use of additives
    • C07C67/52—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/95—Esters of quinone carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/24—Anthracenes; Hydrogenated anthracenes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK02107045.8A 1999-05-07 2002-09-26 純化雙醋瑞因的方法 HK1045498B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI000994A IT1312309B1 (it) 1999-05-07 1999-05-07 Procedimento per la purificazione di diacereina
PCT/EP2000/003691 WO2000068179A1 (en) 1999-05-07 2000-04-25 A process for the purification of diacerein

Publications (2)

Publication Number Publication Date
HK1045498A1 HK1045498A1 (en) 2002-11-29
HK1045498B true HK1045498B (zh) 2005-07-29

Family

ID=11382911

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02107045.8A HK1045498B (zh) 1999-05-07 2002-09-26 純化雙醋瑞因的方法

Country Status (20)

Country Link
EP (1) EP1177164B1 (zh)
JP (1) JP2002544183A (zh)
KR (1) KR100700687B1 (zh)
CN (1) CN1187311C (zh)
AR (1) AR023853A1 (zh)
AT (1) ATE277884T1 (zh)
AU (1) AU772845B2 (zh)
BR (1) BR0010697A (zh)
DE (2) DE1177164T1 (zh)
DK (1) DK1177164T3 (zh)
ES (1) ES2171364T3 (zh)
HK (1) HK1045498B (zh)
IL (1) IL146171A0 (zh)
IT (1) IT1312309B1 (zh)
MX (1) MXPA01011317A (zh)
PL (1) PL199648B1 (zh)
PT (1) PT1177164E (zh)
SI (1) SI1177164T1 (zh)
TR (1) TR200103177T2 (zh)
WO (1) WO2000068179A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1318574B1 (it) * 2000-06-13 2003-08-27 Synteco Spa Procedimento per la purificazione di diacereina.
ITMI20022535A1 (it) * 2002-11-29 2004-05-30 Synteco Spa Procedimento per la purificazione della diacereina.
KR100885677B1 (ko) 2007-05-22 2009-02-25 주식회사 엔지켐 디아세레인의 정제 방법
CN102264683B (zh) * 2008-12-09 2014-07-09 Evultis公司 制备非基因毒性二乙酰大黄酸(双醋瑞因)的方法以及包含非基因毒性二乙酰大黄酸的制剂
WO2011030350A1 (en) 2009-09-08 2011-03-17 Lupin Limited Eco-friendly method for catalytic aerial oxidation of aloe-emodin to rheinal
ITTO20110120A1 (it) 2011-02-11 2012-08-12 Icrom Spa Un nuovo processo di purificazione per derivati antrachinonici

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1264545B1 (it) * 1993-07-30 1996-10-02 Medidom Lab Procedimento per la preparazione della diacereina
CH689279A5 (fr) * 1995-02-07 1999-01-29 Steba Beheer Bv Procédé de purification de la diacétylrhéine.
IT1292132B1 (it) * 1997-06-11 1999-01-25 Synteco S R L Procedimento per la preparazione di diacereina

Also Published As

Publication number Publication date
AU772845B2 (en) 2004-05-06
KR20010113905A (ko) 2001-12-28
AU4913600A (en) 2000-11-21
ES2171364T3 (es) 2005-04-16
HK1045498A1 (en) 2002-11-29
BR0010697A (pt) 2002-02-05
DE1177164T1 (de) 2003-03-06
SI1177164T1 (en) 2005-02-28
EP1177164B1 (en) 2004-09-29
KR100700687B1 (ko) 2007-03-27
AR023853A1 (es) 2002-09-04
ES2171364T1 (es) 2002-09-16
JP2002544183A (ja) 2002-12-24
ITMI990994A1 (it) 2000-11-07
IL146171A0 (en) 2002-07-25
WO2000068179A1 (en) 2000-11-16
DK1177164T3 (da) 2005-01-31
PL351547A1 (en) 2003-05-05
EP1177164A1 (en) 2002-02-06
PL199648B1 (pl) 2008-10-31
TR200103177T2 (tr) 2002-02-21
CN1187311C (zh) 2005-02-02
ATE277884T1 (de) 2004-10-15
DE60014356D1 (de) 2004-11-04
DE60014356T2 (de) 2005-02-17
PT1177164E (pt) 2004-12-31
CN1349495A (zh) 2002-05-15
MXPA01011317A (es) 2003-07-14
IT1312309B1 (it) 2002-04-15

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20140425