TR200103177T2 - Diaserein saflaştırılması için işlem. - Google Patents

Diaserein saflaştırılması için işlem.

Info

Publication number
TR200103177T2
TR200103177T2 TR2001/03177T TR200103177T TR200103177T2 TR 200103177 T2 TR200103177 T2 TR 200103177T2 TR 2001/03177 T TR2001/03177 T TR 2001/03177T TR 200103177 T TR200103177 T TR 200103177T TR 200103177 T2 TR200103177 T2 TR 200103177T2
Authority
TR
Turkey
Prior art keywords
diacerein
purification
acetic anhydride
acid
acetic
Prior art date
Application number
TR2001/03177T
Other languages
English (en)
Inventor
Sinistri Monica
Sinistri Roberto
Original Assignee
Synteco S.Pa.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synteco S.Pa. filed Critical Synteco S.Pa.
Publication of TR200103177T2 publication Critical patent/TR200103177T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/95—Esters of quinone carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/48—Separation; Purification; Stabilisation; Use of additives
    • C07C67/52—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/24—Anthracenes; Hydrogenated anthracenes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Diasereinin hazirlanmasi için bir islem olup, burada diaserein ham ürünün asetik asit ve asetik anhidrür çözeltilerinin bir karisimi veya sadece asetik anhidrür ile kristallestirilmesi, ardindan çözeltinin etilendiaminotetraasetik asit ile herhangi bir eser kromu uzaklastirmak için islenmesiyle saflastirilir.
TR2001/03177T 1999-05-07 2000-04-25 Diaserein saflaştırılması için işlem. TR200103177T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI000994A IT1312309B1 (it) 1999-05-07 1999-05-07 Procedimento per la purificazione di diacereina

Publications (1)

Publication Number Publication Date
TR200103177T2 true TR200103177T2 (tr) 2002-02-21

Family

ID=11382911

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/03177T TR200103177T2 (tr) 1999-05-07 2000-04-25 Diaserein saflaştırılması için işlem.

Country Status (20)

Country Link
EP (1) EP1177164B1 (tr)
JP (1) JP2002544183A (tr)
KR (1) KR100700687B1 (tr)
CN (1) CN1187311C (tr)
AR (1) AR023853A1 (tr)
AT (1) ATE277884T1 (tr)
AU (1) AU772845B2 (tr)
BR (1) BR0010697A (tr)
DE (2) DE60014356T2 (tr)
DK (1) DK1177164T3 (tr)
ES (1) ES2171364T3 (tr)
HK (1) HK1045498B (tr)
IL (1) IL146171A0 (tr)
IT (1) IT1312309B1 (tr)
MX (1) MXPA01011317A (tr)
PL (1) PL199648B1 (tr)
PT (1) PT1177164E (tr)
SI (1) SI1177164T1 (tr)
TR (1) TR200103177T2 (tr)
WO (1) WO2000068179A1 (tr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1318574B1 (it) * 2000-06-13 2003-08-27 Synteco Spa Procedimento per la purificazione di diacereina.
ITMI20022535A1 (it) * 2002-11-29 2004-05-30 Synteco Spa Procedimento per la purificazione della diacereina.
KR100885677B1 (ko) 2007-05-22 2009-02-25 주식회사 엔지켐 디아세레인의 정제 방법
BRPI0917627A2 (pt) * 2008-12-09 2015-11-17 Evultis Sa "processo para produzir diacereína não genotóxica, diacereína não genotíxica, cápsulas e formulações farmacêuticas"
WO2011030350A1 (en) 2009-09-08 2011-03-17 Lupin Limited Eco-friendly method for catalytic aerial oxidation of aloe-emodin to rheinal
ITTO20110120A1 (it) 2011-02-11 2012-08-12 Icrom Spa Un nuovo processo di purificazione per derivati antrachinonici

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1264545B1 (it) * 1993-07-30 1996-10-02 Medidom Lab Procedimento per la preparazione della diacereina
CH689279A5 (fr) * 1995-02-07 1999-01-29 Steba Beheer Bv Procédé de purification de la diacétylrhéine.
IT1292132B1 (it) * 1997-06-11 1999-01-25 Synteco S R L Procedimento per la preparazione di diacereina

Also Published As

Publication number Publication date
PL199648B1 (pl) 2008-10-31
ES2171364T3 (es) 2005-04-16
ATE277884T1 (de) 2004-10-15
DE60014356D1 (de) 2004-11-04
DE60014356T2 (de) 2005-02-17
IL146171A0 (en) 2002-07-25
EP1177164B1 (en) 2004-09-29
BR0010697A (pt) 2002-02-05
ES2171364T1 (es) 2002-09-16
MXPA01011317A (es) 2003-07-14
ITMI990994A1 (it) 2000-11-07
HK1045498A1 (en) 2002-11-29
IT1312309B1 (it) 2002-04-15
KR100700687B1 (ko) 2007-03-27
KR20010113905A (ko) 2001-12-28
DK1177164T3 (da) 2005-01-31
AU4913600A (en) 2000-11-21
EP1177164A1 (en) 2002-02-06
WO2000068179A1 (en) 2000-11-16
HK1045498B (zh) 2005-07-29
JP2002544183A (ja) 2002-12-24
CN1187311C (zh) 2005-02-02
AU772845B2 (en) 2004-05-06
PT1177164E (pt) 2004-12-31
CN1349495A (zh) 2002-05-15
DE1177164T1 (de) 2003-03-06
AR023853A1 (es) 2002-09-04
SI1177164T1 (en) 2005-02-28
PL351547A1 (en) 2003-05-05

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