PL341712A1 - Tramadole purification process - Google Patents

Tramadole purification process

Info

Publication number
PL341712A1
PL341712A1 PL99341712A PL34171299A PL341712A1 PL 341712 A1 PL341712 A1 PL 341712A1 PL 99341712 A PL99341712 A PL 99341712A PL 34171299 A PL34171299 A PL 34171299A PL 341712 A1 PL341712 A1 PL 341712A1
Authority
PL
Poland
Prior art keywords
tramadole
purification process
purification
tramadole purification
Prior art date
Application number
PL99341712A
Inventor
Nicholas Archer
Stewart Cairns
Melville Mitchell
Helen Ogden
Original Assignee
Macfarlan Smith Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Macfarlan Smith Ltd filed Critical Macfarlan Smith Ltd
Publication of PL341712A1 publication Critical patent/PL341712A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL99341712A 1998-01-14 1999-01-14 Tramadole purification process PL341712A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9800656.2A GB9800656D0 (en) 1998-01-14 1998-01-14 Improved purification process
PCT/GB1999/000013 WO1999036390A1 (en) 1998-01-14 1999-01-14 Purification of tramadol

Publications (1)

Publication Number Publication Date
PL341712A1 true PL341712A1 (en) 2001-04-23

Family

ID=10825209

Family Applications (1)

Application Number Title Priority Date Filing Date
PL99341712A PL341712A1 (en) 1998-01-14 1999-01-14 Tramadole purification process

Country Status (12)

Country Link
EP (1) EP1047662A1 (en)
KR (1) KR20010034010A (en)
AU (1) AU744938B2 (en)
CA (1) CA2316991A1 (en)
GB (1) GB9800656D0 (en)
HU (1) HUP0100356A3 (en)
IL (1) IL136957A0 (en)
NZ (1) NZ505129A (en)
PL (1) PL341712A1 (en)
SK (1) SK10352000A3 (en)
TR (1) TR200002022T2 (en)
WO (1) WO1999036390A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100342919B1 (en) * 1999-10-21 2002-07-04 박노중 A preparation and purification for trans isomer of tramadol hydrochloride
US6649783B2 (en) 2001-10-03 2003-11-18 Euro-Celtique, S.A. Synthesis of (+/-)-2-((dimethylamino)methyl)-1-(aryl)cyclohexanols
EP1346978A1 (en) * 2002-03-21 2003-09-24 Jubilant Organosys Limited Process for preparing tramadol hydrochloride and/or tramadol monohydrate
DE10236510A1 (en) * 2002-08-09 2004-02-19 Grünenthal GmbH 2-((Dimethylamino)-methyl)-1-(3-methoxyphenyl)-cyclohexanol preparation, by Grignard reaction in presence of lithium salt and dialkoxyalkane to give high yield of the analgesic trans-isomer tramadol
EP1785412A1 (en) 2005-11-14 2007-05-16 IPCA Laboratories Limited Tramadol recovery process
WO2010032254A1 (en) * 2008-09-22 2010-03-25 Kamud Drugs Pvt . Ltd . Industrial process for cis(+m-2-r(dimethylamino)-methyl-1-(3- methoxyphenyl) cyclohexanol hydrochloride
EP2978739A1 (en) 2013-03-26 2016-02-03 Institut National de la Santé et de la Recherche Médicale (INSERM) Extraction of tramadol from nauclea latifolia smith
USD828429S1 (en) 2015-02-23 2018-09-11 Samsung Electronics Co., Ltd. Digital camera
US20210317086A1 (en) * 2018-08-20 2021-10-14 Mylan Laboratories Limited Tramadol HBR-Celecoxib Co-Crystal

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3652589A (en) * 1967-07-27 1972-03-28 Gruenenthal Chemie 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols
IL103096A (en) * 1992-09-08 1996-12-05 Chemagis Ltd Process for the purification of 2-[(dimethyllamino)methyl]-1-(3-methoxyphenyl) cyclohexanol and its salts
US5877351A (en) * 1997-12-24 1999-03-02 Wyckoff Chemical Company, Inc. Preparation and purification process for 2- (dimethylamino) methyl!-1-(3-methoxphenyl)-cyclohexanol and its salts

Also Published As

Publication number Publication date
HUP0100356A2 (en) 2002-05-29
NZ505129A (en) 2001-11-30
AU2063799A (en) 1999-08-02
IL136957A0 (en) 2001-06-14
CA2316991A1 (en) 1999-07-22
GB9800656D0 (en) 1998-03-11
TR200002022T2 (en) 2000-11-21
AU744938B2 (en) 2002-03-07
EP1047662A1 (en) 2000-11-02
KR20010034010A (en) 2001-04-25
SK10352000A3 (en) 2001-02-12
WO1999036390A1 (en) 1999-07-22
HUP0100356A3 (en) 2002-08-28

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