HK1042338B - 信號細胞的多標記表征 - Google Patents
信號細胞的多標記表征Info
- Publication number
- HK1042338B HK1042338B HK02103067.0A HK02103067A HK1042338B HK 1042338 B HK1042338 B HK 1042338B HK 02103067 A HK02103067 A HK 02103067A HK 1042338 B HK1042338 B HK 1042338B
- Authority
- HK
- Hong Kong
- Prior art keywords
- single cells
- multiple marker
- marker characterization
- characterization
- cells
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Zoology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10611898P | 1998-10-29 | 1998-10-29 | |
PCT/US1999/025324 WO2000026666A2 (en) | 1998-10-29 | 1999-10-29 | Multiple marker characterization of single cells |
Publications (2)
Publication Number | Publication Date |
---|---|
HK1042338A1 HK1042338A1 (en) | 2002-08-09 |
HK1042338B true HK1042338B (zh) | 2005-03-04 |
Family
ID=22309588
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK02103067.0A HK1042338B (zh) | 1998-10-29 | 2002-04-24 | 信號細胞的多標記表征 |
Country Status (8)
Country | Link |
---|---|
US (1) | US20050250155A1 (zh) |
JP (1) | JP2002529704A (zh) |
AU (1) | AU772603B2 (zh) |
CA (1) | CA2350692A1 (zh) |
DE (1) | DE19983691T1 (zh) |
GB (1) | GB2361996B (zh) |
HK (1) | HK1042338B (zh) |
WO (1) | WO2000026666A2 (zh) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6362832B1 (en) * | 1999-09-01 | 2002-03-26 | Packard Bioscience Company | Method and system for overlaying at least three microarray images to obtain a multicolor composite image |
AU2002307054A1 (en) * | 2001-03-30 | 2002-10-15 | Didier Adehl | Detection of abnormal cells |
WO2004077021A2 (en) * | 2003-02-27 | 2004-09-10 | Lesko Stephen A | Standardized evaluation of therapeutic efficacy based on cellular biomarkers |
US7413868B2 (en) * | 2003-11-05 | 2008-08-19 | Trellis Bioscience, Inc. | Use of particulate labels in bioanalyte detection methods |
US20090075305A1 (en) * | 2005-05-02 | 2009-03-19 | The Brigham And Womern's Hospital, Inc. | Diagnostic serum antibody profiling |
US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
JP4986449B2 (ja) * | 2005-12-27 | 2012-07-25 | 株式会社エスアールエル | 浮遊細胞の検査方法 |
JP4943504B2 (ja) | 2006-06-02 | 2012-05-30 | ファイザー・プロダクツ・インク | 循環腫瘍細胞アッセイ |
US20080050739A1 (en) | 2006-06-14 | 2008-02-28 | Roland Stoughton | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
EP2589668A1 (en) | 2006-06-14 | 2013-05-08 | Verinata Health, Inc | Rare cell analysis using sample splitting and DNA tags |
EP2029779A4 (en) | 2006-06-14 | 2010-01-20 | Living Microsystems Inc | HIGHLY PARALLEL SNP GENOTYPING UTILIZATION FOR FETAL DIAGNOSIS |
US8137912B2 (en) | 2006-06-14 | 2012-03-20 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
DE102006040513A1 (de) * | 2006-08-30 | 2008-03-27 | Skinsystec Gmbh | Verfahren zur quantitativen Bestimmung der Kolokalisation von Molekülmarkern in Gewebeschnitten |
US8642347B2 (en) | 2008-01-31 | 2014-02-04 | The Brigham And Women's Hospital, Inc. | Urinary CA125 peptides as biomarkers of ovarian cancer |
WO2009145815A2 (en) | 2008-04-01 | 2009-12-03 | The Brigham And Women's Hospital, Inc. | Biomarkers of ovarian cancer |
CA3069081C (en) | 2008-09-20 | 2023-05-23 | The Board Of Trustees Of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuploidy by sequencing |
US20150004253A1 (en) * | 2012-01-20 | 2015-01-01 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Method for the prognosis of survival time of a patient suffering from a solid cancer |
JP5935207B2 (ja) * | 2012-01-31 | 2016-06-15 | 国立大学法人山口大学 | イメージサイトメーターを利用した染色体多倍性を示し、かつ、細胞増殖能を有する細胞の有無を判定する方法 |
JP5970223B2 (ja) | 2012-03-30 | 2016-08-17 | シスメックス株式会社 | 癌化情報提供方法および癌化情報提供装置 |
CN102749243B (zh) * | 2012-07-16 | 2014-05-14 | 浙江大学舟山海洋研究中心 | 一种虾类胚胎的细胞核染色方法 |
SE1351503A1 (sv) * | 2013-12-16 | 2015-01-07 | Per Fogelstrand | System och metod för fluorescensmikroskopi med detektering av ljusemission från multipla fluorokromer |
US10627389B2 (en) | 2015-05-26 | 2020-04-21 | Incelldx, Inc. | Methods of assessing cellular breast samples and compositions for use in practicing the same |
EP3304074B1 (en) | 2015-05-26 | 2019-10-16 | Creatv Microtech, Inc. | Use of circulating tumor cell mitotic index in cancer stratification and diagnostics |
WO2018030547A1 (ja) * | 2016-08-12 | 2018-02-15 | 日立化成株式会社 | 血中循環癌細胞の検出方法及び血中循環癌細胞を検出するための前処理方法 |
KR101926117B1 (ko) | 2017-08-18 | 2018-12-06 | 주식회사 싸이토젠 | 안드로겐 수용체의 변이체 기반 전립선암환자 스크리닝 방법 |
Family Cites Families (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7115709B1 (en) * | 1986-01-16 | 2006-10-03 | The Regents Of The University Of California | Methods of staining target chromosomal DNA employing high complexity nucleic acid probes |
WO1989003890A1 (en) * | 1987-10-08 | 1989-05-05 | Cancer Biologics, Incorporated | Chromosome banding by monoclonal antibodies to nuclear proteins |
US5817462A (en) * | 1995-02-21 | 1998-10-06 | Applied Spectral Imaging | Method for simultaneous detection of multiple fluorophores for in situ hybridization and multicolor chromosome painting and banding |
US5936731A (en) * | 1991-02-22 | 1999-08-10 | Applied Spectral Imaging Ltd. | Method for simultaneous detection of multiple fluorophores for in situ hybridization and chromosome painting |
US5646001A (en) * | 1991-03-25 | 1997-07-08 | Immunivest Corporation | Affinity-binding separation and release of one or more selected subset of biological entities from a mixed population thereof |
JPH06510672A (ja) * | 1991-11-05 | 1994-12-01 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | サプレッサーおよび前駆細胞 |
US5637469A (en) * | 1992-05-01 | 1997-06-10 | Trustees Of The University Of Pennsylvania | Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems |
BR9306867A (pt) * | 1992-07-17 | 1998-12-08 | Aprogenex Inc | Enriquecimento e identificação de células fetais do sangue materno para a hibridização in situ |
DE4228389C2 (de) * | 1992-08-26 | 1994-07-21 | Kuebler Gmbh Dr | Gewinnung und Kultivierung transformierter Zellen |
US5674694A (en) * | 1993-09-21 | 1997-10-07 | Biologic & Immunologic Science Laboratories, Inc. | Clonogenic assay for detecting micro levels of tumor cells in hematopoietic samples |
US6025128A (en) * | 1994-09-29 | 2000-02-15 | The University Of Tulsa | Prediction of prostate cancer progression by analysis of selected predictive parameters |
US5633945A (en) * | 1994-10-05 | 1997-05-27 | Compucyte Corporation | Accuracy in cell mitosis analysis |
US6117985A (en) * | 1995-06-16 | 2000-09-12 | Stemcell Technologies Inc. | Antibody compositions for preparing enriched cell preparations |
US6718053B1 (en) * | 1996-11-27 | 2004-04-06 | Chromavision Medical Systems, Inc. | Method and apparatus for automated image analysis of biological specimens |
US6344550B1 (en) * | 1996-01-11 | 2002-02-05 | Corixa Corporation | Compositions and methods for the treatment and diagnosis of breast cancer |
WO1997038313A1 (en) * | 1996-04-05 | 1997-10-16 | The Johns Hopkins University | A method of enriching rare cells |
JP2000512744A (ja) * | 1996-05-16 | 2000-09-26 | アフィメトリックス,インコーポレイテッド | 標識材料を検出するシステムおよび方法 |
US5989835A (en) * | 1997-02-27 | 1999-11-23 | Cellomics, Inc. | System for cell-based screening |
US6169816B1 (en) * | 1997-05-14 | 2001-01-02 | Applied Imaging, Inc. | Identification of objects of interest using multiple illumination schemes and finding overlap of features in corresponding multiple images |
US6197523B1 (en) * | 1997-11-24 | 2001-03-06 | Robert A. Levine | Method for the detection, identification, enumeration and confirmation of circulating cancer and/or hematologic progenitor cells in whole blood |
US20020172987A1 (en) * | 1998-02-12 | 2002-11-21 | Terstappen Leon W.M.M. | Methods and reagents for the rapid and efficient isolation of circulating cancer cells |
US20010018192A1 (en) * | 1998-02-12 | 2001-08-30 | Terstappen Leon W.M.M. | Labeled cells for use as an internal functional control in rare cell detection assays |
WO1999041613A1 (en) * | 1998-02-12 | 1999-08-19 | Immunivest | Methods and reagents for the rapid and efficient isolation of circulating cancer cells |
US6210910B1 (en) * | 1998-03-02 | 2001-04-03 | Trustees Of Tufts College | Optical fiber biosensor array comprising cell populations confined to microcavities |
US6606413B1 (en) * | 1998-06-01 | 2003-08-12 | Trestle Acquisition Corp. | Compression packaged image transmission for telemicroscopy |
AU2876900A (en) * | 1999-02-10 | 2000-08-29 | Cell Works Inc. | Class characterization of circulating cancer cells isolated from body fluids andmethods of use |
WO2000062247A1 (en) * | 1999-04-13 | 2000-10-19 | Chromavision Medical Systems, Inc. | Histological reconstruction and automated image analysis |
US20030199685A1 (en) * | 2001-03-12 | 2003-10-23 | Monogen, Inc. | Cell-based detection and differentiation of disease states |
US20030190602A1 (en) * | 2001-03-12 | 2003-10-09 | Monogen, Inc. | Cell-based detection and differentiation of disease states |
US7863012B2 (en) * | 2004-02-17 | 2011-01-04 | Veridex, Llc | Analysis of circulating tumor cells, fragments, and debris |
US7312085B2 (en) * | 2002-04-01 | 2007-12-25 | Fluidigm Corporation | Microfluidic particle-analysis systems |
US7272252B2 (en) * | 2002-06-12 | 2007-09-18 | Clarient, Inc. | Automated system for combining bright field and fluorescent microscopy |
CA2504481A1 (en) * | 2002-10-30 | 2004-05-21 | Pointilliste, Inc. | Systems for capture and analysis of biological particles and methods using the systems |
JPWO2004048976A1 (ja) * | 2002-11-22 | 2006-03-23 | 第一化学薬品株式会社 | 黄色ブドウ球菌の検査方法 |
WO2004077021A2 (en) * | 2003-02-27 | 2004-09-10 | Lesko Stephen A | Standardized evaluation of therapeutic efficacy based on cellular biomarkers |
US20040197832A1 (en) * | 2003-04-03 | 2004-10-07 | Mor Research Applications Ltd. | Non-invasive prenatal genetic diagnosis using transcervical cells |
US20040197839A1 (en) * | 2003-04-04 | 2004-10-07 | Bioview Ltd. | Methods of detecting cancer cells in biological samples |
US20060094109A1 (en) * | 2004-11-02 | 2006-05-04 | Immunivest Corporation | Device and method for analytical cell imaging |
US20070037173A1 (en) * | 2005-08-12 | 2007-02-15 | Allard Jeffrey W | Circulating tumor cells (CTC's): early assessment of time to progression, survival and response to therapy in metastatic cancer patients |
US20070059716A1 (en) * | 2005-09-15 | 2007-03-15 | Ulysses Balis | Methods for detecting fetal abnormality |
JP2009529887A (ja) * | 2006-03-13 | 2009-08-27 | イコニシス インコーポレーテッド | 胎児細胞およびガン細胞を診断する非侵襲的方法 |
-
1999
- 1999-10-29 GB GB0111742A patent/GB2361996B/en not_active Expired - Fee Related
- 1999-10-29 AU AU14552/00A patent/AU772603B2/en not_active Ceased
- 1999-10-29 CA CA002350692A patent/CA2350692A1/en not_active Abandoned
- 1999-10-29 JP JP2000579996A patent/JP2002529704A/ja not_active Withdrawn
- 1999-10-29 WO PCT/US1999/025324 patent/WO2000026666A2/en active IP Right Grant
- 1999-10-29 DE DE19983691T patent/DE19983691T1/de not_active Withdrawn
-
2002
- 2002-04-24 HK HK02103067.0A patent/HK1042338B/zh not_active IP Right Cessation
-
2005
- 2005-07-18 US US11/182,897 patent/US20050250155A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE19983691T1 (de) | 2001-11-29 |
WO2000026666A2 (en) | 2000-05-11 |
GB2361996B (en) | 2004-05-12 |
HK1042338A1 (en) | 2002-08-09 |
JP2002529704A (ja) | 2002-09-10 |
GB2361996A (en) | 2001-11-07 |
WO2000026666A3 (en) | 2000-10-26 |
US20050250155A1 (en) | 2005-11-10 |
GB0111742D0 (en) | 2001-07-04 |
AU1455200A (en) | 2000-05-22 |
WO2000026666A9 (en) | 2001-08-02 |
AU772603B2 (en) | 2004-05-06 |
CA2350692A1 (en) | 2000-05-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Change of ownership |
Owner name: CELL WORKS DIAGNOSTICS INC. Free format text: FORMER OWNER(S): CELL WORKS INC |
|
CHPA | Change of a particular in the register (except of change of ownership) | ||
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20081029 |