HK1038017A1 - Novel 2,3,3a,4,9,9a hexahydro-8-hydroxy-1h-benzÄfÜindoles, a method for the production thereof, and their use as medicaments. - Google Patents

Novel 2,3,3a,4,9,9a hexahydro-8-hydroxy-1h-benzÄfÜindoles, a method for the production thereof, and their use as medicaments.

Info

Publication number
HK1038017A1
HK1038017A1 HK01108875A HK01108875A HK1038017A1 HK 1038017 A1 HK1038017 A1 HK 1038017A1 HK 01108875 A HK01108875 A HK 01108875A HK 01108875 A HK01108875 A HK 01108875A HK 1038017 A1 HK1038017 A1 HK 1038017A1
Authority
HK
Hong Kong
Prior art keywords
hexahydro
hydroxy
benzäfüindoles
medicaments
novel
Prior art date
Application number
HK01108875A
Other languages
English (en)
Inventor
Matthias Grauert
Christoph Hoenke
Adrian Carter
Wolf-Dietrich Bechtel
Thomas Weiser
Rainer Palluk
Uwe Pschorn
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of HK1038017A1 publication Critical patent/HK1038017A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK01108875A 1998-07-31 2001-12-19 Novel 2,3,3a,4,9,9a hexahydro-8-hydroxy-1h-benzÄfÜindoles, a method for the production thereof, and their use as medicaments. HK1038017A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19834714A DE19834714A1 (de) 1998-07-31 1998-07-31 Neue 2,3,3a,4,9,9a-Hexahydro-8-hydroxy-1H-ben[f]indole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
PCT/EP1999/005222 WO2000007986A1 (de) 1998-07-31 1999-07-22 Neue 2,3,3a,4,9,9a-hexahydro-8-hydroxy-1h-benz[f]indole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
HK1038017A1 true HK1038017A1 (en) 2002-03-01

Family

ID=7876092

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01108875A HK1038017A1 (en) 1998-07-31 2001-12-19 Novel 2,3,3a,4,9,9a hexahydro-8-hydroxy-1h-benzÄfÜindoles, a method for the production thereof, and their use as medicaments.

Country Status (30)

Country Link
US (1) US6051583A (xx)
EP (1) EP1100780B1 (xx)
JP (1) JP2002522418A (xx)
KR (1) KR20010072142A (xx)
CN (1) CN1147470C (xx)
AT (1) ATE360611T1 (xx)
AU (1) AU763834B2 (xx)
BG (1) BG105178A (xx)
BR (1) BR9912605A (xx)
CA (1) CA2336783C (xx)
CO (1) CO5080748A1 (xx)
DE (2) DE19834714A1 (xx)
EA (1) EA003370B1 (xx)
EE (1) EE200100062A (xx)
ES (1) ES2285851T3 (xx)
HK (1) HK1038017A1 (xx)
HU (1) HUP0103518A3 (xx)
ID (1) ID28292A (xx)
IL (1) IL140863A0 (xx)
MY (1) MY133085A (xx)
NO (1) NO20010513D0 (xx)
NZ (1) NZ510246A (xx)
PL (1) PL345808A1 (xx)
SK (1) SK1502001A3 (xx)
TR (1) TR200100316T2 (xx)
TW (1) TW464643B (xx)
UA (1) UA68388C2 (xx)
WO (1) WO2000007986A1 (xx)
YU (1) YU5501A (xx)
ZA (1) ZA200007770B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0002666D0 (en) 2000-02-04 2000-03-29 Univ London Blockade of voltage dependent sodium channels
DK1458386T3 (da) * 2001-12-27 2007-08-13 Ortho Mcneil Pharm Inc Aroylpyrrolheteroaryl- og methanolforbindelser til behandling af en lidelse i centralnervesystemet

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2057912C (en) * 1989-07-13 1996-10-29 Chiu-Hong Lin (1,2n) and (3,2n)-carbocyclic-2-amino tetralin derivatives
EP0586553A1 (en) * 1991-05-20 1994-03-16 The Upjohn Company Carboxamido-(3,2n)-carbocyclic-2-aminotetralin derivatives
GB9612153D0 (en) * 1996-06-11 1996-08-14 Smithkline Beecham Plc Compounds

Also Published As

Publication number Publication date
HUP0103518A3 (en) 2002-12-28
ES2285851T3 (es) 2007-11-16
US6051583A (en) 2000-04-18
CN1310707A (zh) 2001-08-29
BR9912605A (pt) 2001-05-02
YU5501A (sh) 2003-04-30
SK1502001A3 (en) 2001-09-11
ZA200007770B (en) 2002-01-17
ID28292A (id) 2001-05-10
EA003370B1 (ru) 2003-04-24
TW464643B (en) 2001-11-21
ATE360611T1 (de) 2007-05-15
CA2336783A1 (en) 2000-02-17
NO20010513L (no) 2001-01-30
BG105178A (en) 2001-12-29
UA68388C2 (en) 2004-08-16
NO20010513D0 (no) 2001-01-30
EE200100062A (et) 2002-06-17
MY133085A (en) 2007-10-31
CO5080748A1 (es) 2001-09-25
IL140863A0 (en) 2002-02-10
AU763834B2 (en) 2003-07-31
DE19834714A1 (de) 2000-02-03
EP1100780A1 (de) 2001-05-23
CA2336783C (en) 2009-04-28
EP1100780B1 (de) 2007-04-25
AU5162699A (en) 2000-02-28
HUP0103518A2 (hu) 2002-01-28
KR20010072142A (ko) 2001-07-31
NZ510246A (en) 2003-08-29
JP2002522418A (ja) 2002-07-23
CN1147470C (zh) 2004-04-28
PL345808A1 (en) 2002-01-02
WO2000007986A1 (de) 2000-02-17
EA200100107A1 (ru) 2001-08-27
TR200100316T2 (tr) 2001-07-23
DE59914314D1 (de) 2007-06-06

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20080722