HK1037629A1 - Substituted imidazo [1,2a]azines as selective inhibitors of cox-2 - Google Patents

Substituted imidazo [1,2a]azines as selective inhibitors of cox-2

Info

Publication number
HK1037629A1
HK1037629A1 HK01108500A HK01108500A HK1037629A1 HK 1037629 A1 HK1037629 A1 HK 1037629A1 HK 01108500 A HK01108500 A HK 01108500A HK 01108500 A HK01108500 A HK 01108500A HK 1037629 A1 HK1037629 A1 HK 1037629A1
Authority
HK
Hong Kong
Prior art keywords
azines
cox
selective inhibitors
substituted imidazo
imidazo
Prior art date
Application number
HK01108500A
Other languages
English (en)
Inventor
Gallemi Carles Farrerons
Bono Ignacio-Jose Miquel
Serrat Ana Maria Fernandez
Guasch Ferran Gimenez
Garcia Andres Fernandez
Vidal Carlos Monserrat
Arnal Carmen Lagunas
Original Assignee
S A L V A T Lab Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by S A L V A T Lab Sa filed Critical S A L V A T Lab Sa
Publication of HK1037629A1 publication Critical patent/HK1037629A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK01108500A 1998-08-03 2001-12-04 Substituted imidazo [1,2a]azines as selective inhibitors of cox-2 HK1037629A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009801652A ES2140354B1 (es) 1998-08-03 1998-08-03 Imidazo (1,2a) azinas sustituidas como inhibidores selectivos de la cox-2.
PCT/ES1999/000235 WO2000008024A1 (es) 1998-08-03 1999-07-23 IMIDAZO[1,2a]AZINAS SUSTITUIDAS COMO INHIBIDORES SELECTIVOS DE LA COX-2

Publications (1)

Publication Number Publication Date
HK1037629A1 true HK1037629A1 (en) 2002-02-15

Family

ID=8304755

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01108500A HK1037629A1 (en) 1998-08-03 2001-12-04 Substituted imidazo [1,2a]azines as selective inhibitors of cox-2

Country Status (31)

Country Link
US (1) US6670365B1 (xx)
EP (1) EP1104762B1 (xx)
JP (1) JP2002522438A (xx)
KR (1) KR20010079602A (xx)
CN (1) CN1131865C (xx)
AP (1) AP2001002082A0 (xx)
AT (1) ATE224391T1 (xx)
AU (1) AU749770B2 (xx)
BG (1) BG105299A (xx)
BR (1) BR9912968A (xx)
CA (1) CA2339187A1 (xx)
CZ (1) CZ291783B6 (xx)
DE (1) DE69903046T2 (xx)
DK (1) DK1104762T3 (xx)
EA (1) EA003399B1 (xx)
ES (2) ES2140354B1 (xx)
HK (1) HK1037629A1 (xx)
HU (1) HUP0103004A3 (xx)
ID (1) ID28539A (xx)
IL (1) IL141242A0 (xx)
MX (1) MXPA01001332A (xx)
NO (1) NO20010568L (xx)
NZ (1) NZ510196A (xx)
OA (1) OA11592A (xx)
PL (1) PL345804A1 (xx)
PT (1) PT1104762E (xx)
SK (1) SK1662001A3 (xx)
TR (1) TR200100359T2 (xx)
WO (1) WO2000008024A1 (xx)
YU (1) YU7401A (xx)
ZA (1) ZA200101632B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8241622B2 (en) * 2001-07-13 2012-08-14 University Of Iowa Research Foundation Adeno-associated virus vectors with intravector heterologous terminal palindromic sequences
US20030100594A1 (en) * 2001-08-10 2003-05-29 Pharmacia Corporation Carbonic anhydrase inhibitor
DE10247271A1 (de) * 2002-10-10 2004-08-26 Grünenthal GmbH Substituierte C-Imidazo[1,2-a]pyridin-3-yle
DE10256881A1 (de) * 2002-12-05 2004-06-24 Beiersdorf Ag Neue topische Verwendung von Bis-Arylimidazo[1,2-a]thiolanderivaten
AU2004237439B2 (en) 2003-05-07 2009-09-10 Osteologix A/S Treating cartilage/bone conditions with water-soluble strontium salts
EA009038B1 (ru) * 2003-07-30 2007-10-26 Лабораториос С.А.Л.В.А.Т., С.А. Замещенные имидазопиримидины для предупреждения и лечения рака
WO2007034278A2 (en) * 2005-09-19 2007-03-29 Pfizer Products Inc. Fused imidazole derivatives as c3a receptor antagonists
US20070265350A1 (en) * 2005-12-30 2007-11-15 University Of Iowa Research Foundation Method of identifying compounds useful to treat neuronal degenerative diseases
WO2007096764A2 (en) * 2006-02-27 2007-08-30 Glenmark Pharmaceuticals S.A. Bicyclic heteroaryl derivatives as cannabinoid receptor modulators
CN101861316B (zh) * 2007-11-14 2013-08-21 奥梅-杨森制药有限公司 咪唑并[1,2-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途
TW201018667A (en) * 2008-10-01 2010-05-16 Synta Pharmaceuticals Corp Compounds for inflammation and immune-related uses
GB201321732D0 (en) 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic agents
WO2017139381A1 (en) 2016-02-08 2017-08-17 University Of Iowa Research Foundation Methods to produce chimeric adeno-associated virus/bocavirus parvovirus
CA3016985C (en) 2016-03-07 2023-07-04 University Of Iowa Research Foundation Aav-mediated expression using a synthetic promoter and enhancer
US11142775B2 (en) 2017-01-13 2021-10-12 University Of Iowa Research Foundation Bocaparvovirus small noncoding RNA and uses thereof
WO2022195579A1 (en) 2021-03-15 2022-09-22 Saul Yedgar Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2785133A (en) * 1954-03-26 1957-03-12 Gen Aniline & Film Corp Compositions for a method of whitening fine fabrics
US3455924A (en) * 1967-02-08 1969-07-15 Upjohn Co Dianisylimidazoles
WO1992010190A1 (en) * 1990-12-13 1992-06-25 Smithkline Beecham Corporation Novel csaids
AU3648993A (en) * 1992-03-17 1993-10-21 Nippon Shinyaku Co. Ltd. Imidazopyridine derivative and medicine
US5620999A (en) 1994-07-28 1997-04-15 Weier; Richard M. Benzenesulfonamide subtituted imidazolyl compounds for the treatment of inflammation
JPH11501049A (ja) * 1995-04-04 1999-01-26 グラクソ、グループ、リミテッド イミダゾ〔１，２−ａ〕ピリジン誘導体
UA57002C2 (uk) * 1995-10-13 2003-06-16 Мерк Фросст Кенада Енд Ко./Мерк Фросст Кенада Енд Сі. Похідне (метилсульфоніл)феніл-2-(5н)-фуранону, фармацевтична композиція та спосіб лікування

Also Published As

Publication number Publication date
CA2339187A1 (en) 2000-02-17
ES2140354B1 (es) 2000-11-01
NZ510196A (en) 2002-09-27
PT1104762E (pt) 2002-11-29
HUP0103004A3 (en) 2003-03-28
ES2182546T3 (es) 2003-03-01
ZA200101632B (en) 2001-08-30
OA11592A (en) 2004-07-30
BR9912968A (pt) 2001-05-08
IL141242A0 (en) 2002-03-10
ATE224391T1 (de) 2002-10-15
DK1104762T3 (da) 2002-10-21
ID28539A (id) 2001-05-31
JP2002522438A (ja) 2002-07-23
US6670365B1 (en) 2003-12-30
CZ291783B6 (cs) 2003-05-14
DE69903046D1 (de) 2002-10-24
DE69903046T2 (de) 2003-05-22
SK1662001A3 (en) 2001-08-06
EP1104762A1 (en) 2001-06-06
CN1131865C (zh) 2003-12-24
YU7401A (sh) 2003-10-31
MXPA01001332A (es) 2002-11-29
CZ2001433A3 (cs) 2001-08-15
WO2000008024A1 (es) 2000-02-17
NO20010568D0 (no) 2001-02-02
AP2001002082A0 (en) 2001-03-31
ES2140354A1 (es) 2000-02-16
EA200100212A1 (ru) 2001-08-27
EA003399B1 (ru) 2003-04-24
AU749770B2 (en) 2002-07-04
HUP0103004A2 (hu) 2002-01-28
CN1321157A (zh) 2001-11-07
KR20010079602A (ko) 2001-08-22
AU4782499A (en) 2000-02-28
BG105299A (en) 2001-11-30
PL345804A1 (en) 2002-01-02
EP1104762B1 (en) 2002-09-18
TR200100359T2 (tr) 2001-06-21
NO20010568L (no) 2001-04-02

Similar Documents

Publication Publication Date Title
PL348208A1 (en) Pyrazolopyridine derivatives as selective cox-2 inhibitors
PL380733A1 (pl) Pochodne 3, 3-difenylopropyloamin, sposoby ich wytwarzania, ich zastosowanie medyczne oraz kompozycja farmaceutyczna
PL339059A1 (en) Derivatives of 2,3-diarylpyraxole [1,5-b] pyridazines, their production and application as inhibitors of cyclooxygenase 2(cox-2)
HK1064670A1 (en) Pyridine-3-carboxylic acid derivatives
IL141445A0 (en) Benzazine derivatives as phosphodiesterase 4 inhibitors
IL141242A0 (en) Substituted imidazo [1,2a] azines as selective inhibitors of cox-2
IL136885A0 (en) 2,3-substituted indole compounds as cox-2 inhibitors
HUP0101753A3 (en) Boring-tool
PL349364A1 (en) Use of pyridazino[4,5-b
MXPA00012647A (es) Derivados n-sustituidos de acido 5-oxiiminobarbiturico.
IL141446A0 (en) Benzazine derivatives as phosphodiesterase 4 inhibitors
DE69900220D1 (de) Diaza-spiro[3,5]nonan-Derivate
IL137518A0 (en) Derivatives of 1,2,4-oxadiazolone
AU1817700A (en) 1-carboxymethyl-2-oxo-azepan derivatives useful as selective inhibitors of mmp-12
PL338354A1 (en) Method of obtaining avermectin compounds
ZA991233B (en) Use of thiadiazolo pyridine derivatives.
SI1104762T1 (en) Substituted imidazo(1,2a)azines as selective inhibitors of cox-2
PL334144A1 (en) Novel derivatives of pyrolydine, composition containing and method of obtaining them
AU1719700A (en) Selective inhibitors of mmp-12
PL341713A1 (en) Derivatives of spiropiperidine
EP1017687A4 (en) METHOD FOR PRODUCING 3-ARYLOXY-4-ARYL-FURAN-2-ONE AS INHIBITORS OF COX-2
AU1874600A (en) Homopiperazine derivatives as selective emopamil inhibitors
PL330680A1 (en) Method of purifying 3-substituted derivatives of diketones
ZA9811564B (en) Derivatives of 1,3,4-oxadiazolone
PL329699A1 (en) N-aryloxyalkyl derivatives of d,l,l(-) and d(+)-trans-2-amino-1-cyclohexanol

Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20060723