DK1104762T3 - Substituerede imidazo[1,2a]aziner som selektive COX-2-inhibitorer - Google Patents

Substituerede imidazo[1,2a]aziner som selektive COX-2-inhibitorer

Info

Publication number
DK1104762T3
DK1104762T3 DK99931266T DK99931266T DK1104762T3 DK 1104762 T3 DK1104762 T3 DK 1104762T3 DK 99931266 T DK99931266 T DK 99931266T DK 99931266 T DK99931266 T DK 99931266T DK 1104762 T3 DK1104762 T3 DK 1104762T3
Authority
DK
Denmark
Prior art keywords
azines
inhibitors
selective cox
substituted imidazo
imidazo
Prior art date
Application number
DK99931266T
Other languages
English (en)
Inventor
Gallemi Carles Farrerons
Bono Ignacio-Jose Miquel
Serrat Ana Maria Fernandez
Vidal Carlos Monserrat
Arnal Carmen Lagunas
Guasch Ferran Gimenez
Garcia Andres Fernandez
Original Assignee
S A L V A T Lab Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by S A L V A T Lab Sa filed Critical S A L V A T Lab Sa
Application granted granted Critical
Publication of DK1104762T3 publication Critical patent/DK1104762T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DK99931266T 1998-08-03 1999-07-23 Substituerede imidazo[1,2a]aziner som selektive COX-2-inhibitorer DK1104762T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009801652A ES2140354B1 (es) 1998-08-03 1998-08-03 Imidazo (1,2a) azinas sustituidas como inhibidores selectivos de la cox-2.
PCT/ES1999/000235 WO2000008024A1 (es) 1998-08-03 1999-07-23 IMIDAZO[1,2a]AZINAS SUSTITUIDAS COMO INHIBIDORES SELECTIVOS DE LA COX-2

Publications (1)

Publication Number Publication Date
DK1104762T3 true DK1104762T3 (da) 2002-10-21

Family

ID=8304755

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99931266T DK1104762T3 (da) 1998-08-03 1999-07-23 Substituerede imidazo[1,2a]aziner som selektive COX-2-inhibitorer

Country Status (31)

Country Link
US (1) US6670365B1 (da)
EP (1) EP1104762B1 (da)
JP (1) JP2002522438A (da)
KR (1) KR20010079602A (da)
CN (1) CN1131865C (da)
AP (1) AP2001002082A0 (da)
AT (1) ATE224391T1 (da)
AU (1) AU749770B2 (da)
BG (1) BG105299A (da)
BR (1) BR9912968A (da)
CA (1) CA2339187A1 (da)
CZ (1) CZ291783B6 (da)
DE (1) DE69903046T2 (da)
DK (1) DK1104762T3 (da)
EA (1) EA003399B1 (da)
ES (2) ES2140354B1 (da)
HK (1) HK1037629A1 (da)
HU (1) HUP0103004A3 (da)
ID (1) ID28539A (da)
IL (1) IL141242A0 (da)
MX (1) MXPA01001332A (da)
NO (1) NO20010568L (da)
NZ (1) NZ510196A (da)
OA (1) OA11592A (da)
PL (1) PL345804A1 (da)
PT (1) PT1104762E (da)
SK (1) SK1662001A3 (da)
TR (1) TR200100359T2 (da)
WO (1) WO2000008024A1 (da)
YU (1) YU7401A (da)
ZA (1) ZA200101632B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8241622B2 (en) * 2001-07-13 2012-08-14 University Of Iowa Research Foundation Adeno-associated virus vectors with intravector heterologous terminal palindromic sequences
US20030100594A1 (en) * 2001-08-10 2003-05-29 Pharmacia Corporation Carbonic anhydrase inhibitor
DE10247271A1 (de) * 2002-10-10 2004-08-26 Grünenthal GmbH Substituierte C-Imidazo[1,2-a]pyridin-3-yle
DE10256881A1 (de) * 2002-12-05 2004-06-24 Beiersdorf Ag Neue topische Verwendung von Bis-Arylimidazo[1,2-a]thiolanderivaten
PT1534305E (pt) 2003-05-07 2007-02-28 Osteologix As Tratamento de afecções cartilagineas / osseas com sais de estroncio hidrosoluveis
ATE380816T1 (de) * 2003-07-30 2007-12-15 S A L V A T Lab Sa Substituierte imidazopyrimidine zur prävention und behandlung von krebs
WO2007034278A2 (en) * 2005-09-19 2007-03-29 Pfizer Products Inc. Fused imidazole derivatives as c3a receptor antagonists
WO2007079141A2 (en) * 2005-12-30 2007-07-12 University Of Iowa Research Foundation Method of identifying compounds useful to treat neuronal degenerative diseases
WO2007096764A2 (en) * 2006-02-27 2007-08-30 Glenmark Pharmaceuticals S.A. Bicyclic heteroaryl derivatives as cannabinoid receptor modulators
EP2220083B1 (en) * 2007-11-14 2017-07-19 Janssen Pharmaceuticals, Inc. Imidazo[1,2-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
US20100130522A1 (en) * 2008-10-01 2010-05-27 Synta Pharmaceuticals Corp. Compounds for inflammation and immune-related uses
GB201321732D0 (en) 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic agents
WO2017139381A1 (en) 2016-02-08 2017-08-17 University Of Iowa Research Foundation Methods to produce chimeric adeno-associated virus/bocavirus parvovirus
CA3198936A1 (en) 2016-03-07 2017-09-14 University Of Iowa Research Foundation Aav-mediated expression using a synthetic promoter and enhancer
IL305573A (en) 2021-03-15 2023-10-01 Saul Yedgar Hyaluronic acid conjugated with dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment or suppression of inflammatory diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2785133A (en) * 1954-03-26 1957-03-12 Gen Aniline & Film Corp Compositions for a method of whitening fine fabrics
US3455924A (en) * 1967-02-08 1969-07-15 Upjohn Co Dianisylimidazoles
CA2098177A1 (en) * 1990-12-13 1992-06-13 Jerry L. Adams Csaids
MX9301458A (es) * 1992-03-17 1994-01-31 Nippon Shinyaku Co Ltd Derivados de imidazopiridina y composicion farmaceutica que los comprende.
US5620999A (en) * 1994-07-28 1997-04-15 Weier; Richard M. Benzenesulfonamide subtituted imidazolyl compounds for the treatment of inflammation
HUP9801602A3 (en) * 1995-04-04 1999-01-28 Glaxo Group Ltd Imidazo[1,2-a]pyridine derivatives, process for their production, pharmaceutical compositions and use thereof
UA57002C2 (uk) * 1995-10-13 2003-06-16 Мерк Фросст Кенада Енд Ко./Мерк Фросст Кенада Енд Сі. Похідне (метилсульфоніл)феніл-2-(5н)-фуранону, фармацевтична композиція та спосіб лікування

Also Published As

Publication number Publication date
ID28539A (id) 2001-05-31
MXPA01001332A (es) 2002-11-29
HK1037629A1 (en) 2002-02-15
AU4782499A (en) 2000-02-28
CN1131865C (zh) 2003-12-24
CA2339187A1 (en) 2000-02-17
AP2001002082A0 (en) 2001-03-31
ES2140354B1 (es) 2000-11-01
EP1104762A1 (en) 2001-06-06
SK1662001A3 (en) 2001-08-06
DE69903046T2 (de) 2003-05-22
YU7401A (sh) 2003-10-31
ATE224391T1 (de) 2002-10-15
KR20010079602A (ko) 2001-08-22
ES2182546T3 (es) 2003-03-01
CZ2001433A3 (cs) 2001-08-15
JP2002522438A (ja) 2002-07-23
NO20010568D0 (no) 2001-02-02
NZ510196A (en) 2002-09-27
HUP0103004A3 (en) 2003-03-28
OA11592A (en) 2004-07-30
HUP0103004A2 (hu) 2002-01-28
EA003399B1 (ru) 2003-04-24
CN1321157A (zh) 2001-11-07
AU749770B2 (en) 2002-07-04
ES2140354A1 (es) 2000-02-16
EP1104762B1 (en) 2002-09-18
PT1104762E (pt) 2002-11-29
DE69903046D1 (de) 2002-10-24
CZ291783B6 (cs) 2003-05-14
ZA200101632B (en) 2001-08-30
WO2000008024A1 (es) 2000-02-17
TR200100359T2 (tr) 2001-06-21
EA200100212A1 (ru) 2001-08-27
PL345804A1 (en) 2002-01-02
BR9912968A (pt) 2001-05-08
NO20010568L (no) 2001-04-02
IL141242A0 (en) 2002-03-10
US6670365B1 (en) 2003-12-30
BG105299A (en) 2001-11-30

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