HK1036991A1 - New 12,13-(pyranosyl)-indolo(2,3-a)pyrrolo(3,4-c)carbazole and 12,13-(pyranosyl)-furo(3,4-c)indolo(2,3-a-)carbazole compounds, a process for their preparation and pharmaceutical compositions containing them. - Google Patents

New 12,13-(pyranosyl)-indolo(2,3-a)pyrrolo(3,4-c)carbazole and 12,13-(pyranosyl)-furo(3,4-c)indolo(2,3-a-)carbazole compounds, a process for their preparation and pharmaceutical compositions containing them.

Info

Publication number
HK1036991A1
HK1036991A1 HK01107825A HK01107825A HK1036991A1 HK 1036991 A1 HK1036991 A1 HK 1036991A1 HK 01107825 A HK01107825 A HK 01107825A HK 01107825 A HK01107825 A HK 01107825A HK 1036991 A1 HK1036991 A1 HK 1036991A1
Authority
HK
Hong Kong
Prior art keywords
indolo
carbazole
alkyl
nrarb
aryl
Prior art date
Application number
HK01107825A
Other languages
English (en)
Inventor
Michelle Prudhomme
Pascale Moreau
Fabrice Anizon
Christelle Marminon
Ghanem Atassi
Alain Pierre
Bruno Pfeiffer
Pierre Renard
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of HK1036991A1 publication Critical patent/HK1036991A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
HK01107825A 1999-11-17 2001-11-08 New 12,13-(pyranosyl)-indolo(2,3-a)pyrrolo(3,4-c)carbazole and 12,13-(pyranosyl)-furo(3,4-c)indolo(2,3-a-)carbazole compounds, a process for their preparation and pharmaceutical compositions containing them. HK1036991A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9914433A FR2801054B1 (fr) 1999-11-17 1999-11-17 Nouveaux derives de 12,13-(pyranosyl)-indolo[2,3-a]pyrrolo [3,4-c]carbazole et 12,13-(pyranosyl)-furo[3,4-c]indolo [2,3-a]carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
HK1036991A1 true HK1036991A1 (en) 2002-01-25

Family

ID=9552202

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01107825A HK1036991A1 (en) 1999-11-17 2001-11-08 New 12,13-(pyranosyl)-indolo(2,3-a)pyrrolo(3,4-c)carbazole and 12,13-(pyranosyl)-furo(3,4-c)indolo(2,3-a-)carbazole compounds, a process for their preparation and pharmaceutical compositions containing them.

Country Status (23)

Country Link
US (1) US6569858B2 (zh)
EP (1) EP1101770B1 (zh)
JP (1) JP3602050B2 (zh)
KR (1) KR100453980B1 (zh)
CN (1) CN1152040C (zh)
AT (1) ATE237625T1 (zh)
AU (1) AU771584B2 (zh)
BR (1) BR0005426A (zh)
CA (1) CA2325779C (zh)
DE (1) DE60002142T2 (zh)
DK (1) DK1101770T3 (zh)
EA (1) EA004737B1 (zh)
ES (1) ES2197061T3 (zh)
FR (1) FR2801054B1 (zh)
HK (1) HK1036991A1 (zh)
HU (1) HUP0004574A3 (zh)
MX (1) MXPA00010899A (zh)
NO (1) NO20005796L (zh)
NZ (1) NZ508231A (zh)
PL (1) PL343879A1 (zh)
PT (1) PT1101770E (zh)
SI (1) SI1101770T1 (zh)
ZA (1) ZA200006729B (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6653290B2 (en) 2000-10-06 2003-11-25 Bristol-Myers Squibb Company Tumor proliferation inhibitors
US6677450B2 (en) * 2000-10-06 2004-01-13 Bristol-Myers Squibb Company Topoisomerase inhibitors
US6610727B2 (en) 2000-10-06 2003-08-26 Bristol-Myers Squibb Company Anhydro sugar derivatives of indolocarbazoles
YU74103A (sh) 2001-03-22 2006-05-25 Bristol-Myers Squibb Company Topoizomeraza i selektivni citotoksični šećerni derivati indolopirolokarbazola
FR2826653B1 (fr) * 2001-06-29 2005-10-14 Servier Lab Nouveaux derives de pyrido-pyrido-pyrrolo[3,2-g]pyrrolo [3,4-e]-indole et pyrido-pyrrolo[2,3-a]pyrrolo[3,4-c] carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2831169B1 (fr) * 2001-10-22 2003-12-12 Servier Lab Nouveaux derives d'hydroxyalkyle indolocarbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
ES2326459B1 (es) 2008-04-08 2010-05-28 Universidad De Oviedo Indolocarbazoles glicosilados, su procedimiento de obtencion y sus usos.
CN104031052B (zh) * 2014-05-20 2016-06-08 中国科学院南海海洋研究所 抗生素Indimicins A–E及其制备方法和在制备抗肿瘤药物中的应用
US10513515B2 (en) 2017-08-25 2019-12-24 Biotheryx, Inc. Ether compounds and uses thereof
US11236103B2 (en) 2018-07-27 2022-02-01 Biotheryx, Inc. Bifunctional compounds
RU2726801C1 (ru) * 2019-10-16 2020-07-15 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ онкологии им. Н.Н. Блохина" Минздрава России) Средство для терапии опухолей
EP4143329A4 (en) 2020-04-28 2024-10-16 Anwita Biosciences Inc INTERLEUKIN-2 POLYPEPTIDES AND FUSION PROTEINS THEREOF, AS WELL AS THEIR PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC APPLICATIONS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015578A (en) * 1989-03-23 1991-05-14 Bristol-Myers Squibb Company BMY-41950 antitumor antibiotic
JPH05140168A (ja) * 1991-11-13 1993-06-08 Asahi Chem Ind Co Ltd インドロカルバゾール誘導体及び該化合物を有効成分とする抗腫瘍剤
NZ245203A (en) * 1991-11-29 1997-07-27 Banyu Pharma Co Ltd 5h-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6h)-dione derivatives substituted in position-13 by a pentose or hexose group; corresponding indolo-furano(anhydride)intermediates
JPH07112987A (ja) * 1993-10-14 1995-05-02 Asahi Chem Ind Co Ltd スタウロスポリン糖部分変換誘導体
CO4940430A1 (es) * 1997-07-07 2000-07-24 Novartis Ag Compuestos policiclicos que contienen estaurosporina hidrogenada con propiedades farmacologicas convenientes y un efecto inhibidor sobre el crecimiento de las celulas tumorales

Also Published As

Publication number Publication date
BR0005426A (pt) 2001-07-03
KR100453980B1 (ko) 2004-10-20
NO20005796L (no) 2001-05-18
HU0004574D0 (zh) 2001-02-28
ATE237625T1 (de) 2003-05-15
NO20005796D0 (no) 2000-11-16
JP2001139578A (ja) 2001-05-22
SI1101770T1 (en) 2003-08-31
HUP0004574A2 (hu) 2001-10-28
PT1101770E (pt) 2003-07-31
MXPA00010899A (es) 2002-05-23
KR20010051775A (ko) 2001-06-25
EP1101770A1 (fr) 2001-05-23
HUP0004574A3 (en) 2001-12-28
DK1101770T3 (da) 2003-08-04
CA2325779A1 (fr) 2001-05-17
PL343879A1 (en) 2001-05-21
AU771584B2 (en) 2004-03-25
DE60002142T2 (de) 2004-03-18
CA2325779C (fr) 2006-07-11
EP1101770B1 (fr) 2003-04-16
CN1152040C (zh) 2004-06-02
JP3602050B2 (ja) 2004-12-15
ZA200006729B (en) 2001-06-05
EA004737B1 (ru) 2004-08-26
ES2197061T3 (es) 2004-01-01
NZ508231A (en) 2001-09-28
DE60002142D1 (de) 2003-05-22
EA200001078A1 (ru) 2001-06-25
US6569858B2 (en) 2003-05-27
CN1303859A (zh) 2001-07-18
FR2801054B1 (fr) 2003-06-13
FR2801054A1 (fr) 2001-05-18
AU7168100A (en) 2002-01-03
US20020055510A1 (en) 2002-05-09

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20091117