HK1031723A1 - Cycloalkene derivatives, process for producing thesame, and use. - Google Patents

Cycloalkene derivatives, process for producing thesame, and use.

Info

Publication number
HK1031723A1
HK1031723A1 HK01102186A HK01102186A HK1031723A1 HK 1031723 A1 HK1031723 A1 HK 1031723A1 HK 01102186 A HK01102186 A HK 01102186A HK 01102186 A HK01102186 A HK 01102186A HK 1031723 A1 HK1031723 A1 HK 1031723A1
Authority
HK
Hong Kong
Prior art keywords
substituents
hydrocarbon group
group optionally
aliphatic hydrocarbon
hydrogen atom
Prior art date
Application number
HK01102186A
Other languages
English (en)
Inventor
Yuzo Ichimori
Ii Masayuki
Katsumi Itoh
Tomoyuki Kitazaki
Junji Yamada
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of HK1031723A1 publication Critical patent/HK1031723A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/14—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Silicon Compounds (AREA)
HK01102186A 1998-03-09 2001-03-26 Cycloalkene derivatives, process for producing thesame, and use. HK1031723A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP5649298 1998-03-09
JP28436298 1998-10-06
PCT/JP1999/001103 WO1999046242A1 (fr) 1998-03-09 1999-03-08 Derives de cycloalcene, leur procede de fabrication et d'utilisation

Publications (1)

Publication Number Publication Date
HK1031723A1 true HK1031723A1 (en) 2001-06-22

Family

ID=26397446

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01102186A HK1031723A1 (en) 1998-03-09 2001-03-26 Cycloalkene derivatives, process for producing thesame, and use.

Country Status (20)

Country Link
US (1) US6495604B1 (xx)
EP (2) EP1524263A1 (xx)
JP (2) JP3665712B2 (xx)
KR (4) KR100779889B1 (xx)
CN (1) CN100432049C (xx)
AT (1) ATE287393T1 (xx)
AU (1) AU747521B2 (xx)
BR (1) BR9908610A (xx)
CA (1) CA2320467C (xx)
DE (1) DE69923300T2 (xx)
DK (1) DK1063228T5 (xx)
ES (1) ES2232114T3 (xx)
HK (1) HK1031723A1 (xx)
HU (1) HU230061B1 (xx)
ID (1) ID25649A (xx)
NO (1) NO326426B1 (xx)
NZ (1) NZ505874A (xx)
PT (1) PT1063228E (xx)
RU (1) RU2214398C2 (xx)
WO (1) WO1999046242A1 (xx)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1524263A1 (en) 1998-03-09 2005-04-20 Takeda Pharmaceutical Company Limited prodrugs containing cycloalkene derivatives
US20040220103A1 (en) * 1999-04-19 2004-11-04 Immunex Corporation Soluble tumor necrosis factor receptor treatment of medical disorders
WO2001010826A1 (fr) 1999-08-06 2001-02-15 Takeda Chemical Industries, Ltd. Composes a cycle aromatique substitues, procede de production, et utilisation
WO2001040498A1 (fr) * 1999-11-29 2001-06-07 Takeda Chemical Industries, Ltd. Procede de production de derives optiquement actifs du cyclohexene et de leurs intermediaires
KR100784752B1 (ko) * 2000-02-04 2007-12-13 다케다 야쿠힌 고교 가부시키가이샤 안정한 에멀젼 조성물
JP4863553B2 (ja) * 2000-02-04 2012-01-25 武田薬品工業株式会社 安定な乳化組成物
EP1310248A4 (en) 2000-08-10 2008-05-21 Takeda Pharmaceutical PHARMACEUTICAL COMPOSITION
JP4922507B2 (ja) * 2000-08-10 2012-04-25 武田薬品工業株式会社 医薬組成物
ATE508109T1 (de) 2000-10-18 2011-05-15 Takeda Pharmaceutical Verfahren zur herstellung von optisch aktiven sulfonamiden und zwischenprodukte zur deren synthese
EP1348443A4 (en) * 2000-12-08 2005-07-06 Takeda Pharmaceutical COMBINED MEDICINES
ATE442143T1 (de) 2001-03-21 2009-09-15 Eisai R&D Man Co Ltd Reduziertes vitamin b2 enthaltende arzneimittel
EP1420783A4 (en) * 2001-08-03 2009-09-30 Takeda Pharmaceutical STABLE EMULSION COMPOSITION
US20060058288A1 (en) * 2002-04-08 2006-03-16 Masayuki Ii Severe sepsis preventive therapeutic agent
CA2547410C (en) 2003-12-03 2013-07-30 Boehringer Ingelheim Pharmaceuticals, Inc. 1,2,3-triazole amide derivatives as inhibitors of cytokie production
MY147790A (en) * 2005-04-28 2013-01-31 Takeda Pharmaceutical Stable emulsion composition
RU2386613C2 (ru) * 2005-09-14 2010-04-20 Дайити Санкио Компани, Лимитед Замещенные циклоалкеновые производные
WO2007114296A1 (ja) 2006-03-30 2007-10-11 Hiroshima University スクリーニング方法
EP2018872A4 (en) * 2006-04-20 2010-06-09 Takeda Pharmaceutical PHARMACEUTICAL PRODUCT
WO2007132825A1 (ja) 2006-05-15 2007-11-22 Takeda Pharmaceutical Company Limited 医薬
EP2039681A4 (en) * 2006-07-07 2009-10-28 Takeda Pharmaceutical CYCLOALKENE DERIVATIVES, PROCESS FOR PRODUCTION OF DERIVATIVES, AND USE THEREOF
JP2008260760A (ja) * 2007-03-12 2008-10-30 Daiichi Sankyo Co Ltd 置換シクロアルケン誘導体を含有する医薬組成物
KR20120118044A (ko) 2010-01-27 2012-10-25 다케다 야쿠힌 고교 가부시키가이샤 항암제로 유도되는 말초 신경 장애를 억제하기 위한 화합물
EP2620434B1 (en) 2010-09-24 2017-01-04 Daiichi Sankyo Company, Limited A method of preparing crystals of a substituted cycloalkene derivative
JP6509112B2 (ja) * 2012-07-03 2019-05-08 プラブダ，ジェイ オキソ関連状態の治療、診断および／またはその進行のモニタリングのための方法
EP2902014B1 (en) 2012-09-26 2019-03-06 Takeda Pharmaceutical Company Limited Process for producing solid particles
EP3294706B1 (en) 2015-05-08 2019-12-04 Takeda Pharmaceutical Company Limited Cyclic compounds
EP3511320A4 (en) 2016-09-09 2020-04-15 Takeda Pharmaceutical Company Limited CYCLIC COMPOUND
EP3585768A4 (en) * 2017-02-24 2020-12-23 Taiwanj Pharmaceuticals Co., Ltd. SULFONAMIDE OR AMIDE COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE PROPHYLAXIS AND / OR TREATMENT OF AUTOIMMUNE, INFLAMMATORY, OR INFECTIOUS DISEASES

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5635491A (en) 1990-11-06 1997-06-03 Nippon Shinyaku Co., Ltd. Lyophilized fatty emulsions and a process for the production thereof
US5576016A (en) 1993-05-18 1996-11-19 Pharmos Corporation Solid fat nanoemulsions as drug delivery vehicles
EP0746318A1 (en) 1994-02-25 1996-12-11 Takeda Chemical Industries, Ltd. Injectable emulsions containing antifungal triazole derivatives
JPH08109165A (ja) * 1994-08-18 1996-04-30 Chugai Pharmaceut Co Ltd 一酸化窒素合成酵素阻害作用を有するアミノ酸誘導体
EP0776886A4 (en) * 1994-08-18 1999-05-12 Chugai Pharmaceutical Co Ltd AMINO ACID DERIVATIVE WITH NITROGEN MONOXIDE SYNTHETASE INHIBITING ACTIVITY
EP1524263A1 (en) 1998-03-09 2005-04-20 Takeda Pharmaceutical Company Limited prodrugs containing cycloalkene derivatives
KR100784752B1 (ko) 2000-02-04 2007-12-13 다케다 야쿠힌 고교 가부시키가이샤 안정한 에멀젼 조성물

Also Published As

Publication number Publication date
JP3665712B2 (ja) 2005-06-29
CA2320467C (en) 2010-05-04
NZ505874A (en) 2003-09-26
ATE287393T1 (de) 2005-02-15
DK1063228T5 (da) 2009-06-15
NO326426B1 (no) 2008-12-01
NO20004485D0 (no) 2000-09-08
US6495604B1 (en) 2002-12-17
HUP0101192A2 (hu) 2001-08-28
CA2320467A1 (en) 1999-09-16
ES2232114T3 (es) 2005-05-16
KR100779889B1 (ko) 2007-11-28
WO1999046242A1 (fr) 1999-09-16
JP2000178246A (ja) 2000-06-27
BR9908610A (pt) 2000-12-05
DK1063228T3 (da) 2005-04-25
KR100577044B1 (ko) 2006-05-08
KR100492098B1 (ko) 2005-06-01
NO20004485L (no) 2000-09-08
EP1063228B1 (en) 2005-01-19
KR20050026075A (ko) 2005-03-14
JP2005232168A (ja) 2005-09-02
KR20060017921A (ko) 2006-02-27
CN100432049C (zh) 2008-11-12
AU2746499A (en) 1999-09-27
PL342826A1 (en) 2001-07-02
HUP0101192A3 (en) 2003-09-29
EP1524263A1 (en) 2005-04-20
PT1063228E (pt) 2005-05-31
ID25649A (id) 2000-10-19
JP4342453B2 (ja) 2009-10-14
CN1291184A (zh) 2001-04-11
DE69923300D1 (de) 2005-02-24
EP1063228A1 (en) 2000-12-27
KR20010034555A (ko) 2001-04-25
AU747521C (en) 1999-09-27
DE69923300T2 (de) 2006-01-05
RU2214398C2 (ru) 2003-10-20
EP1063228A4 (en) 2001-08-08
AU747521B2 (en) 2002-05-16
KR20050071719A (ko) 2005-07-07
HU230061B1 (hu) 2015-06-29

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Legal Events

Date Code Title Description
CHPA Change of a particular in the register (except of change of ownership)
AM Amended specification (according sect 146 of patent law)

Free format text: EP 1063228; [73] TAKEDA PHARMACEUTICAL COMPANY LIMITED; [54] CYCLOALKENE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND USE

PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20160308