HK1030776A1 - Substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia - Google Patents
Substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasiaInfo
- Publication number
- HK1030776A1 HK1030776A1 HK01101679A HK01101679A HK1030776A1 HK 1030776 A1 HK1030776 A1 HK 1030776A1 HK 01101679 A HK01101679 A HK 01101679A HK 01101679 A HK01101679 A HK 01101679A HK 1030776 A1 HK1030776 A1 HK 1030776A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- treatment
- benign prostatic
- prostatic hyperplasia
- substituted pyridino
- arylpiperazines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7532198P | 1998-02-20 | 1998-02-20 | |
| PCT/US1999/003608 WO1999042448A1 (en) | 1998-02-20 | 1999-02-19 | Novel substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1030776A1 true HK1030776A1 (en) | 2001-05-18 |
Family
ID=22124955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK01101679A HK1030776A1 (en) | 1998-02-20 | 2001-03-08 | Substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6218396B1 (cs) |
| EP (1) | EP1054868B1 (cs) |
| JP (1) | JP2002503724A (cs) |
| KR (1) | KR100591028B1 (cs) |
| CN (1) | CN1121390C (cs) |
| AR (1) | AR014626A1 (cs) |
| AT (1) | ATE250580T1 (cs) |
| AU (1) | AU766398B2 (cs) |
| BR (1) | BR9909647A (cs) |
| CZ (1) | CZ294136B6 (cs) |
| DE (1) | DE69911582T2 (cs) |
| DK (1) | DK1054868T3 (cs) |
| ES (1) | ES2209468T3 (cs) |
| HK (1) | HK1030776A1 (cs) |
| HU (1) | HUP0100781A3 (cs) |
| IL (2) | IL137954A0 (cs) |
| NO (1) | NO317103B1 (cs) |
| NZ (1) | NZ506462A (cs) |
| PL (1) | PL342339A1 (cs) |
| PT (1) | PT1054868E (cs) |
| TR (1) | TR200003220T2 (cs) |
| TW (1) | TW565555B (cs) |
| WO (1) | WO1999042448A1 (cs) |
| ZA (1) | ZA991315B (cs) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AP1349A (en) * | 1997-05-12 | 2004-12-17 | Ortho Mcneil Pharm Inc | Arylsubstituted piperazines useful in the treatment of benign prostatic hyperplasia. |
| JP2004511438A (ja) | 2000-08-08 | 2004-04-15 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | イミダゾールを含有しないアリールオキシピペリジン |
| BR0215389A (pt) | 2001-12-28 | 2004-10-26 | Takeda Chemical Industries Ltd | Agente preventivo ou terapêutico para distúrbio urinário, método para prevenir ou tratar distúrbio urinário, uso de um composto, composto, pró-droga, processo para preparar o composto, medicamento, e, método para triar um composto |
| US8470859B2 (en) | 2006-10-23 | 2013-06-25 | Takeda Pharmaceutical Company Limited | Iminopyridine derivative and use thereof |
| MX2010011652A (es) * | 2008-04-23 | 2010-12-06 | Takeda Pharmaceutical | Derivados de iminopiridina y uso de los mismos. |
| US20110039892A1 (en) * | 2008-04-23 | 2011-02-17 | Takeda Pharmaceutical Company Limited | Iminopyridine derivative and use thereof |
| US8481569B2 (en) | 2008-04-23 | 2013-07-09 | Takeda Pharmaceutical Company Limited | Iminopyridine derivatives and use thereof |
| CN103980195A (zh) * | 2014-04-28 | 2014-08-13 | 广州医科大学 | 酰胺类苯基哌嗪衍生物及其盐与在制备治疗良性前列腺增生症药物中的应用 |
| CN108530391B (zh) * | 2018-05-17 | 2022-05-17 | 袁牧 | 一种酰胺类芳基哌嗪衍生物及其制备方法与应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2027898A6 (es) * | 1991-01-24 | 1992-06-16 | Espanola Prod Quimicos | Procedimiento de preparacion de nuevos derivados de la 2-metoxifenilpiperacina. |
| US5403847A (en) | 1992-11-13 | 1995-04-04 | Synaptic Pharmaceutical Corporation | Use of α1C specific compounds to treat benign prostatic hyperlasia |
| IT1266582B1 (it) * | 1993-07-30 | 1997-01-09 | Recordati Chem Pharm | Derivati (di)azacicloesanici e diazacicloeptanici |
| DE4425146A1 (de) * | 1994-07-15 | 1996-01-18 | Basf Ag | Verwendung heterocyclischer Verbindungen |
| US5688795A (en) | 1994-11-08 | 1997-11-18 | Syntex (U.S.A.) Inc. | 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy!-pyridine, pyrimidine and benzene derivatives as α1 -adrenoceptor antagonists |
| AU8130298A (en) * | 1997-07-15 | 1999-02-10 | Sankyo Company Limited | Piperazine derivatives |
-
1999
- 1999-02-18 ZA ZA9901315A patent/ZA991315B/xx unknown
- 1999-02-18 US US09/252,313 patent/US6218396B1/en not_active Expired - Lifetime
- 1999-02-19 BR BR9909647-1A patent/BR9909647A/pt not_active Application Discontinuation
- 1999-02-19 PT PT99934281T patent/PT1054868E/pt unknown
- 1999-02-19 DK DK99934281T patent/DK1054868T3/da active
- 1999-02-19 CZ CZ20003044A patent/CZ294136B6/cs not_active IP Right Cessation
- 1999-02-19 AT AT99934281T patent/ATE250580T1/de not_active IP Right Cessation
- 1999-02-19 IL IL13795499A patent/IL137954A0/xx active IP Right Grant
- 1999-02-19 TR TR2000/03220T patent/TR200003220T2/xx unknown
- 1999-02-19 HU HU0100781A patent/HUP0100781A3/hu unknown
- 1999-02-19 DE DE69911582T patent/DE69911582T2/de not_active Expired - Fee Related
- 1999-02-19 WO PCT/US1999/003608 patent/WO1999042448A1/en active IP Right Grant
- 1999-02-19 CN CN99803027A patent/CN1121390C/zh not_active Expired - Fee Related
- 1999-02-19 EP EP99934281A patent/EP1054868B1/en not_active Expired - Lifetime
- 1999-02-19 ES ES99934281T patent/ES2209468T3/es not_active Expired - Lifetime
- 1999-02-19 KR KR1020007009156A patent/KR100591028B1/ko not_active IP Right Cessation
- 1999-02-19 PL PL99342339A patent/PL342339A1/xx unknown
- 1999-02-19 NZ NZ506462A patent/NZ506462A/en unknown
- 1999-02-19 JP JP2000532400A patent/JP2002503724A/ja active Pending
- 1999-02-19 AU AU33025/99A patent/AU766398B2/en not_active Ceased
- 1999-02-23 AR ARP990100675A patent/AR014626A1/es active IP Right Grant
- 1999-04-02 TW TW088102511A patent/TW565555B/zh not_active IP Right Cessation
-
2000
- 2000-08-18 IL IL137954A patent/IL137954A/en not_active IP Right Cessation
- 2000-08-18 NO NO20004141A patent/NO317103B1/no not_active IP Right Cessation
-
2001
- 2001-03-08 HK HK01101679A patent/HK1030776A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0100781A3 (en) | 2002-12-28 |
| CZ294136B6 (cs) | 2004-10-13 |
| CZ20003044A3 (cs) | 2001-04-11 |
| HUP0100781A2 (hu) | 2001-08-28 |
| EP1054868B1 (en) | 2003-09-24 |
| CN1291188A (zh) | 2001-04-11 |
| US6218396B1 (en) | 2001-04-17 |
| KR100591028B1 (ko) | 2006-06-22 |
| PT1054868E (pt) | 2004-01-30 |
| BR9909647A (pt) | 2000-11-21 |
| IL137954A0 (en) | 2001-10-31 |
| NO20004141D0 (no) | 2000-08-18 |
| WO1999042448A1 (en) | 1999-08-26 |
| ATE250580T1 (de) | 2003-10-15 |
| EP1054868A1 (en) | 2000-11-29 |
| JP2002503724A (ja) | 2002-02-05 |
| KR20010041115A (ko) | 2001-05-15 |
| ZA991315B (en) | 2000-11-20 |
| NO317103B1 (no) | 2004-08-09 |
| AU3302599A (en) | 1999-09-06 |
| TR200003220T2 (tr) | 2001-04-20 |
| DE69911582D1 (de) | 2003-10-30 |
| DE69911582T2 (de) | 2005-09-15 |
| PL342339A1 (en) | 2001-06-04 |
| IL137954A (en) | 2007-06-03 |
| ES2209468T3 (es) | 2004-06-16 |
| TW565555B (en) | 2003-12-11 |
| AR014626A1 (es) | 2001-03-28 |
| NO20004141L (no) | 2000-10-19 |
| NZ506462A (en) | 2003-07-25 |
| CN1121390C (zh) | 2003-09-17 |
| DK1054868T3 (da) | 2003-12-22 |
| AU766398B2 (en) | 2003-10-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PF | Patent in force | ||
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20100219 |