HK1030145A1 - Powdery pernasal compositions - Google Patents
Powdery pernasal compositionsInfo
- Publication number
- HK1030145A1 HK1030145A1 HK01100899A HK01100899A HK1030145A1 HK 1030145 A1 HK1030145 A1 HK 1030145A1 HK 01100899 A HK01100899 A HK 01100899A HK 01100899 A HK01100899 A HK 01100899A HK 1030145 A1 HK1030145 A1 HK 1030145A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- powdery
- compositions
- pernasal
- pernasal compositions
- drug
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Nutrition Science (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP24024298 | 1998-08-26 | ||
PCT/JP1999/004560 WO2000012136A1 (fr) | 1998-08-26 | 1999-08-24 | Compositions en poudre s'administrant par voie nasale |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1030145A1 true HK1030145A1 (en) | 2001-04-27 |
Family
ID=17056580
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK01100899A HK1030145A1 (en) | 1998-08-26 | 2001-02-08 | Powdery pernasal compositions |
Country Status (15)
Country | Link |
---|---|
US (1) | US6428805B1 (de) |
EP (1) | EP1025859B1 (de) |
JP (1) | JP4338313B2 (de) |
KR (1) | KR100611025B1 (de) |
CN (1) | CN1160127C (de) |
AT (1) | ATE331532T1 (de) |
AU (1) | AU762145C (de) |
CA (1) | CA2307607C (de) |
DE (1) | DE69932144T8 (de) |
DK (1) | DK1025859T3 (de) |
ES (1) | ES2263282T3 (de) |
HK (1) | HK1030145A1 (de) |
PT (1) | PT1025859E (de) |
TW (1) | TW553746B (de) |
WO (1) | WO2000012136A1 (de) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2341732C (en) | 1998-08-26 | 2008-08-19 | Teijin Limited | Powder composition for nasal administration |
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
JP4721212B2 (ja) * | 2001-07-05 | 2011-07-13 | 株式会社新日本科学 | インスリンの経鼻投与用組成物 |
ES2300568T3 (es) | 2002-03-20 | 2008-06-16 | Mannkind Corporation | Aparato de inhalacion. |
US20080260838A1 (en) * | 2003-08-01 | 2008-10-23 | Mannkind Corporation | Glucagon-like peptide 1 (glp-1) pharmaceutical formulations |
WO2004073729A1 (ja) | 2003-02-21 | 2004-09-02 | Translational Research Ltd. | 薬物の経鼻投与用組成物 |
CA2519287A1 (en) | 2003-03-27 | 2004-10-14 | Bioactis Limited | Powder medicine applicator for nasal cavity |
US6986944B2 (en) * | 2003-05-20 | 2006-01-17 | Eastman Kodak Company | Core-shell nitro-resin particles and method of preparation |
US8673360B2 (en) | 2004-08-10 | 2014-03-18 | Shin Nippon Biomedical Laboratories, Ltd. | Compositions that enable rapid-acting and highly absorptive intranasal administration |
CA2575692C (en) | 2004-08-20 | 2014-10-14 | Mannkind Corporation | Catalysis of diketopiperazine synthesis |
BR122019022692B1 (pt) | 2004-08-23 | 2023-01-10 | Mannkind Corporation | Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo |
US7115561B2 (en) * | 2004-09-22 | 2006-10-03 | Patterson James A | Medicament composition and method of administration |
US20070111964A1 (en) * | 2005-08-17 | 2007-05-17 | Fleming And Company, Pharmaceuticals | Vitamin B12 nasal spray and method of use |
HUE028691T2 (en) | 2005-09-14 | 2016-12-28 | Mannkind Corp | A method for formulating a drug based on increasing the affinity of crystalline microparticle surfaces towards active ingredients |
EP1986679B1 (de) | 2006-02-22 | 2017-10-25 | MannKind Corporation | Verfahren zur verbesserung der pharmazeutischen eigenschaften von mikropartikeln mit diketopiperazin und einem wirkstoff |
CN101668544B (zh) | 2006-12-26 | 2013-04-24 | 株式会社新日本科学 | 经鼻投用制剂 |
US20100028447A1 (en) | 2007-01-22 | 2010-02-04 | Targacept, Inc. | Intranasal, Buccal, And Sublingual Administration Of Metanicotine Analogs |
JP2011500850A (ja) * | 2007-10-24 | 2011-01-06 | マンカインド コーポレイション | Glp−1による副作用を防止する方法 |
AU2009218060B2 (en) * | 2008-02-28 | 2014-08-28 | Toray Industries, Inc. | Pharmaceutical composition for transnasal administration |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
AR072114A1 (es) | 2008-06-13 | 2010-08-04 | Mannkind Corp | Un inhalador de polvo seco y sistema para suministro de farmacos |
BRPI0914308B8 (pt) | 2008-06-20 | 2021-06-22 | Mannkind Corp | sistema de inalação |
TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
CA2754595C (en) | 2009-03-11 | 2017-06-27 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
EP2429495A4 (de) | 2009-05-15 | 2014-01-22 | Shin Nippon Biomedical Lab Ltd | Intranasale pharmazeutische zusammensetzung mit verbesserter pharmakokinetik |
KR101875969B1 (ko) | 2009-06-12 | 2018-07-06 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
WO2011013003A2 (en) * | 2009-07-31 | 2011-02-03 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal granisetron and nasal applicator |
EP2496295A1 (de) | 2009-11-03 | 2012-09-12 | MannKind Corporation | Vorrichtung und verfahren zur simulation von einatmungsanstrengungen |
RU2571331C1 (ru) | 2010-06-21 | 2015-12-20 | Маннкайнд Корпорейшн | Системы и способы доставки сухих порошковых лекарств |
JP6133270B2 (ja) | 2011-04-01 | 2017-05-24 | マンカインド コーポレイション | 薬剤カートリッジのためのブリスター包装 |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
JP6018640B2 (ja) | 2011-10-24 | 2016-11-02 | マンカインド コーポレイション | 疼痛を緩和するのに有効な鎮痛組成物並びに当該組成物を含む乾燥粉末及び乾燥粉末薬剤輸送システム |
SG11201500218VA (en) | 2012-07-12 | 2015-03-30 | Mannkind Corp | Dry powder drug delivery systems and methods |
US10159644B2 (en) | 2012-10-26 | 2018-12-25 | Mannkind Corporation | Inhalable vaccine compositions and methods |
WO2014144895A1 (en) | 2013-03-15 | 2014-09-18 | Mannkind Corporation | Microcrystalline diketopiperazine compositions and methods |
AU2014290438B2 (en) | 2013-07-18 | 2019-11-07 | Mannkind Corporation | Heat-stable dry powder pharmaceutical compositions and methods |
WO2015021064A1 (en) | 2013-08-05 | 2015-02-12 | Mannkind Corporation | Insufflation apparatus and methods |
US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
US11744967B2 (en) | 2017-09-26 | 2023-09-05 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal delivery devices |
US11234928B2 (en) | 2017-11-27 | 2022-02-01 | Aska Pharmaceutical Co., Ltd. | Powder preparation for nasal administration |
WO2022132018A1 (en) * | 2020-12-16 | 2022-06-23 | Liw Innovation Ab | A new powder composition |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1577196A (en) * | 1977-06-03 | 1980-10-22 | Ile De France | Compositions containing erythromycin and metoclopramide |
JPS59163313A (ja) * | 1983-03-09 | 1984-09-14 | Teijin Ltd | 経鼻投与用ペプチドホルモン類組成物 |
GB2193891B (en) * | 1986-08-18 | 1990-07-25 | Sandoz Ltd | Nasal pharmaceutical composition containing a somatostatin anologue. |
GB9020544D0 (en) * | 1990-09-20 | 1990-10-31 | Sandoz Ltd | Improvements in or relating to organic compounds |
ATE215377T1 (de) * | 1993-07-30 | 2002-04-15 | Teijin Ltd | Pulver zur nasalen verabreichung peptidischer oder proteinischer arzneistoffe |
JPH07242550A (ja) * | 1994-03-02 | 1995-09-19 | Teijin Ltd | 二次性副甲状腺機能亢進症治療剤 |
WO1997031626A1 (fr) * | 1996-02-27 | 1997-09-04 | Teijin Limited | Composition pulverulente destinee a une adminstration nasale |
TW503113B (en) * | 1997-01-16 | 2002-09-21 | Senju Pharma Co | Aqueous suspension for nasal administration |
JP3386349B2 (ja) * | 1997-10-30 | 2003-03-17 | 帝人株式会社 | 水性懸濁医薬品組成物 |
-
1999
- 1999-08-24 ES ES99938613T patent/ES2263282T3/es not_active Expired - Lifetime
- 1999-08-24 DE DE69932144T patent/DE69932144T8/de active Active
- 1999-08-24 JP JP2000567246A patent/JP4338313B2/ja not_active Expired - Fee Related
- 1999-08-24 PT PT99938613T patent/PT1025859E/pt unknown
- 1999-08-24 AU AU53059/99A patent/AU762145C/en not_active Ceased
- 1999-08-24 DK DK99938613T patent/DK1025859T3/da active
- 1999-08-24 CA CA002307607A patent/CA2307607C/en not_active Expired - Fee Related
- 1999-08-24 WO PCT/JP1999/004560 patent/WO2000012136A1/ja active IP Right Grant
- 1999-08-24 EP EP99938613A patent/EP1025859B1/de not_active Expired - Lifetime
- 1999-08-24 US US09/530,203 patent/US6428805B1/en not_active Expired - Lifetime
- 1999-08-24 KR KR1020007004462A patent/KR100611025B1/ko not_active IP Right Cessation
- 1999-08-24 CN CNB998019119A patent/CN1160127C/zh not_active Expired - Fee Related
- 1999-08-24 AT AT99938613T patent/ATE331532T1/de active
- 1999-08-26 TW TW088114652A patent/TW553746B/zh not_active IP Right Cessation
-
2001
- 2001-02-08 HK HK01100899A patent/HK1030145A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69932144T2 (de) | 2007-06-06 |
ATE331532T1 (de) | 2006-07-15 |
CN1287495A (zh) | 2001-03-14 |
AU762145B2 (en) | 2003-06-19 |
CA2307607C (en) | 2008-02-05 |
CN1160127C (zh) | 2004-08-04 |
DK1025859T3 (da) | 2006-10-16 |
DE69932144D1 (de) | 2006-08-10 |
JP4338313B2 (ja) | 2009-10-07 |
EP1025859A1 (de) | 2000-08-09 |
DE69932144T8 (de) | 2007-10-04 |
CA2307607A1 (en) | 2000-03-09 |
AU762145C (en) | 2005-03-17 |
PT1025859E (pt) | 2006-10-31 |
TW553746B (en) | 2003-09-21 |
ES2263282T3 (es) | 2006-12-01 |
AU5305999A (en) | 2000-03-21 |
KR20010031431A (ko) | 2001-04-16 |
EP1025859A4 (de) | 2002-10-16 |
KR100611025B1 (ko) | 2006-08-10 |
EP1025859B1 (de) | 2006-06-28 |
WO2000012136A1 (fr) | 2000-03-09 |
US6428805B1 (en) | 2002-08-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1030145A1 (en) | Powdery pernasal compositions | |
IL139934A0 (en) | Pyrrole substituted 2-indolinone derivatives and pharmaceutical compositions containing the same | |
AU3648399A (en) | Terminally-branched polymeric linkers and polymeric conjugates containing the same | |
IL138899A0 (en) | Amidene derivatives and pharmaceutical compositions containing the same | |
IL140862A (en) | Thiobenzimidazole derivatives and pharmaceutical compositions containing the same | |
PL346530A1 (en) | Azetidine derivatives, preparation and medicines containing them | |
IL110482A0 (en) | 1-benzenesulfonyl-1,3-dihydroindol-2-one derivatives, their preparation and pharmaceutical compositions containing them | |
IL141769A0 (en) | Azetidine derivatives, preparation and medicines containing them | |
AU4314196A (en) | Solid composition with improved solubility and absorbability | |
IL143920A0 (en) | 3-heteroarylidenyl-2-indolinone derivatives and pharmaceutical compositions containing the same | |
HUP0001541A3 (en) | Phthalazinone derivatives and pharmaceutical compositions containing them | |
IL131319A0 (en) | 3-Piperidyl-4- oxoquinazoline derivatives and medicinal compositions containing the same | |
HK1044101A1 (en) | Fibre blend for enteral composition. | |
HK1027585A1 (en) | Improved antiog composition for polyolefin packaging films and use thereof. | |
HK1026197A1 (en) | Pharmaceutically-active dimethyl-(3-aryl-but-3-enyl)-amine compounds. | |
HUP0203505A3 (en) | 2'-substituted 1,1'-biphenyl-2-carbonamides, and pharmaceutical compositions containing said compounds | |
IL143802A0 (en) | Imidazole derivatives and pharmaceutical compositions containing the same | |
HUP0003425A3 (en) | 2-(4-aryl or heteroaryl-piperazin-1-ylmethyl)-1h-indole derivatives and pharmaceutical compositions containing the compounds | |
HUP0100680A3 (en) | Indole derivatives and medicinal compositions containing the same | |
HUP0105075A3 (en) | 3,3-biarylpiperidine and 2,2-biarylmorpholine derivatives, their use and pharmaceutical compositions containing them | |
IL152978A0 (en) | Macromolecular drug complexes and compositions containing the same | |
IL135723A (en) | 1'-Ä4-Ä1-4-Fluorophenyl)-1H-indole-3-ylÜ-1-butylÜ-spiroÄisobenzofuran-1-(3H),4'-piperidineÜhydrohal ogenides and pharmaceutical compositions containing them | |
AU3410099A (en) | Pharmaceutical compositions containing melatonin inclusion complexes | |
ZA991038B (en) | Pyrrolidine and piperidine derivatives. | |
IL136045A0 (en) | Pyridylpyrrole derivatives and pharmaceutical compositions containing the same |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20150824 |