HK1024508A1 - Polypeptides binding to mort-1 and mach, its sequence, preparation, composition and use. - Google Patents

Polypeptides binding to mort-1 and mach, its sequence, preparation, composition and use.

Info

Publication number
HK1024508A1
HK1024508A1 HK00103826A HK00103826A HK1024508A1 HK 1024508 A1 HK1024508 A1 HK 1024508A1 HK 00103826 A HK00103826 A HK 00103826A HK 00103826 A HK00103826 A HK 00103826A HK 1024508 A1 HK1024508 A1 HK 1024508A1
Authority
HK
Hong Kong
Prior art keywords
mort
mach
sequence
preparation
composition
Prior art date
Application number
HK00103826A
Other languages
English (en)
Inventor
David Wallach
Yura Goltsev
Andrei Kovalenko
Eugene Varfolomeev
Vadim Brodianski
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL12036797A external-priority patent/IL120367A0/xx
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Publication of HK1024508A1 publication Critical patent/HK1024508A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472Cysteine endopeptidases (3.4.22)
    • C12N9/6475Interleukin 1-beta convertase-like enzymes (3.4.22.10; 3.4.22.36; 3.4.22.63)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HK00103826A 1997-03-03 2000-06-23 Polypeptides binding to mort-1 and mach, its sequence, preparation, composition and use. HK1024508A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL12036797A IL120367A0 (en) 1997-03-03 1997-03-03 Modulators of the function of FAS receptors and other proteins
IL12075997A IL120759A0 (en) 1997-03-03 1997-05-01 Modulators of the function of fas receptors and other proteins
PCT/IL1998/000098 WO1998039435A1 (en) 1997-03-03 1998-02-26 Cash (caspase homologue) with death effector domain, modulators of the function of fas receptors

Publications (1)

Publication Number Publication Date
HK1024508A1 true HK1024508A1 (en) 2000-10-13

Family

ID=26323378

Family Applications (1)

Application Number Title Priority Date Filing Date
HK00103826A HK1024508A1 (en) 1997-03-03 2000-06-23 Polypeptides binding to mort-1 and mach, its sequence, preparation, composition and use.

Country Status (19)

Country Link
US (1) US7419804B2 (no)
EP (1) EP0977842A1 (no)
JP (1) JP2002500508A (no)
KR (1) KR100544776B1 (no)
CN (1) CN1148446C (no)
AU (1) AU740223B2 (no)
BG (1) BG64799B1 (no)
BR (1) BR9808173A (no)
CA (1) CA2281484A1 (no)
EA (1) EA003269B1 (no)
EE (1) EE9900384A (no)
HK (1) HK1024508A1 (no)
HU (1) HUP0000913A3 (no)
IL (3) IL120759A0 (no)
NO (1) NO994250L (no)
NZ (1) NZ337143A (no)
PL (1) PL193394B1 (no)
SK (1) SK117599A3 (no)
WO (1) WO1998039435A1 (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19713393C2 (de) * 1997-04-01 2002-12-05 Apotech Res & Dev Ltd Flip-Gen und Flip-Protein
DE19713434C1 (de) * 1997-04-01 1998-09-24 Deutsches Krebsforsch Protein zur Inhibierung von Apoptose
JP2002520025A (ja) * 1998-07-08 2002-07-09 メルク フロスト カナダ アンド カンパニー 哺乳動物ded−カスパーゼ相同体ユサルピン
US7052834B1 (en) 1998-12-31 2006-05-30 St. Jude Children's Research Hospital Tumor suppressor protein involved in death signaling, and diagnostics, therapeutics, and screening based on this protein
WO2000039347A1 (en) * 1998-12-31 2000-07-06 St. Jude Children's Research Hospital A tumor suppressor protein involved in death signaling, and diagnostics, therapeutics, and screening based on this protein
US20020174450A1 (en) * 2000-12-11 2002-11-21 Allen Keith D. Transgenic mice containing cash gene disruptions
CN110988354A (zh) * 2019-11-15 2020-04-10 同济大学 一种分泌蛋白Caspase1在早期心梗诊断试剂中的应用
CN116426678B (zh) * 2023-03-27 2024-03-22 中国热带农业科学院三亚研究院 与番木瓜果肉果糖含量相关的snp分子标记及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL114615A0 (en) 1995-07-16 1995-11-27 Yeda Res & Dev Modulators of the function of fas receptors and other proteins
EP0841399A3 (en) * 1996-11-12 1998-07-08 Smithkline Beecham Corporation Mammalian fin-1 nucleic acid (a caspase) and protein sequences and uses therefor
JP2001511011A (ja) 1997-01-21 2001-08-07 ヒューマン ジノーム サイエンシーズ,インコーポレイテッド 腫瘍壊死因子レセプター−1誘導性アポトーシスおよびcd−95誘導性アポトーシスの新規なインヒビターである、i−flice
US6242569B1 (en) 1997-02-05 2001-06-05 Tularik, Inc. Regulators of apoptosis
DE19713393C2 (de) * 1997-04-01 2002-12-05 Apotech Res & Dev Ltd Flip-Gen und Flip-Protein
US6207458B1 (en) * 1998-05-07 2001-03-27 University Of Washigton/Stowers Insitute For Medical Research Proteins capable of regulating NF-κB JNK and apoptosis pathways and methods of using the same

Also Published As

Publication number Publication date
EA199900794A1 (ru) 2000-04-24
CA2281484A1 (en) 1998-09-11
BG64799B1 (bg) 2006-04-28
NO994250D0 (no) 1999-09-02
US20060216788A1 (en) 2006-09-28
IL120759A0 (en) 1997-09-30
NZ337143A (en) 2001-12-21
HUP0000913A3 (en) 2001-11-28
EP0977842A1 (en) 2000-02-09
WO1998039435A1 (en) 1998-09-11
AU740223B2 (en) 2001-11-01
NO994250L (no) 1999-11-02
HUP0000913A2 (hu) 2000-06-28
EE9900384A (et) 2000-04-17
SK117599A3 (en) 2000-05-16
CN1148446C (zh) 2004-05-05
US7419804B2 (en) 2008-09-02
BR9808173A (pt) 2000-05-16
CN1249780A (zh) 2000-04-05
JP2002500508A (ja) 2002-01-08
IL131247A0 (en) 2001-01-28
EA003269B1 (ru) 2003-02-27
PL193394B1 (pl) 2007-02-28
KR20000075721A (ko) 2000-12-26
BG103693A (en) 2000-05-31
KR100544776B1 (ko) 2006-01-23
IL131247A (en) 2007-08-19
AU6112698A (en) 1998-09-22
PL335448A1 (en) 2000-04-25

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090226