HK1021186A1 - Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment - Google Patents

Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment

Info

Publication number
HK1021186A1
HK1021186A1 HK00100158A HK00100158A HK1021186A1 HK 1021186 A1 HK1021186 A1 HK 1021186A1 HK 00100158 A HK00100158 A HK 00100158A HK 00100158 A HK00100158 A HK 00100158A HK 1021186 A1 HK1021186 A1 HK 1021186A1
Authority
HK
Hong Kong
Prior art keywords
compounds
treatment
methods
compositions containing
carbapenem antibacterial
Prior art date
Application number
HK00100158A
Other languages
English (en)
Inventor
Robert R Wilkening
Ronald W Ratcliffe
Timothy A Blizzard
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9609741.5A external-priority patent/GB9609741D0/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of HK1021186A1 publication Critical patent/HK1021186A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/14—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK00100158A 1996-04-24 2000-01-10 Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment HK1021186A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1618496P 1996-04-24 1996-04-24
GBGB9609741.5A GB9609741D0 (en) 1996-05-10 1996-05-10 Carbapenem antibacterial compounds compositions containing such componds and methods of treatment
PCT/US1997/006626 WO1997040048A1 (en) 1996-04-24 1997-04-21 Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment

Publications (1)

Publication Number Publication Date
HK1021186A1 true HK1021186A1 (en) 2000-06-02

Family

ID=26309297

Family Applications (1)

Application Number Title Priority Date Filing Date
HK00100158A HK1021186A1 (en) 1996-04-24 2000-01-10 Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment

Country Status (31)

Country Link
EP (1) EP0906313B1 (zh)
JP (1) JP3176068B2 (zh)
KR (1) KR20000010599A (zh)
CN (1) CN1074767C (zh)
AR (1) AR006810A1 (zh)
AT (1) ATE260915T1 (zh)
AU (1) AU707459B2 (zh)
BG (1) BG102949A (zh)
BR (1) BR9708864A (zh)
CA (1) CA2252402C (zh)
CO (1) CO4990968A1 (zh)
CZ (1) CZ340798A3 (zh)
DE (1) DE69727931T2 (zh)
EA (1) EA001296B1 (zh)
EE (1) EE03689B1 (zh)
ES (1) ES2216142T3 (zh)
HK (1) HK1021186A1 (zh)
HR (1) HRP970213A2 (zh)
HU (1) HUP9901778A3 (zh)
ID (1) ID16662A (zh)
IL (1) IL126480A0 (zh)
IS (1) IS4861A (zh)
NO (1) NO984949L (zh)
NZ (1) NZ332183A (zh)
PE (1) PE64298A1 (zh)
PL (1) PL186881B1 (zh)
SK (1) SK283550B6 (zh)
TR (1) TR199802140T2 (zh)
TW (1) TW539677B (zh)
WO (1) WO1997040048A1 (zh)
YU (1) YU46298A (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7163522B1 (en) 1994-03-02 2007-01-16 Scimed Life Systems, Inc. Block copolymer elastomer catheter balloons
US6406457B1 (en) 1994-03-02 2002-06-18 Scimed Life Systems, Inc. Block copolymer elastomer catheter balloons
US5908936A (en) * 1997-05-13 1999-06-01 Merck & Co., Inc. Process for synthesizing carbapenem intermediates
CA2287931A1 (en) * 1997-05-13 1998-11-19 Merck & Co., Inc. Process for synthesizing carbapenem intermediates
DE69813870T2 (de) * 1997-10-23 2004-02-05 Merck & Co., Inc. Antibakterielle carbapenem-verbindungen, zusammensetzungen, die diese verbindungen enthalten und behandlungsmethoden
JP2002509856A (ja) * 1997-10-23 2002-04-02 メルク エンド カムパニー インコーポレーテッド カルバペネム系抗菌化合物、組成物および治療方法
US6140318A (en) 1997-10-23 2000-10-31 Merck & Co., Inc. Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
US6271222B1 (en) * 1998-05-28 2001-08-07 Merck & Co., Inc. Penem antibacterial compounds, compositions and methods of treatment
EP1104424B1 (en) * 1998-06-17 2004-04-07 Merck & Co., Inc. Process for the synthesis of carbapenem intermediates
US6265395B1 (en) * 1998-06-25 2001-07-24 Merck & Co., Inc. Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
CA2335571A1 (en) * 1998-06-25 1999-12-29 Merck & Co. Inc. (heterocyclic) methyl substituted carbapenem antibacterials
US7672747B2 (en) 2000-03-30 2010-03-02 Lam Research Corporation Recipe-and-component control module and methods thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0429341A3 (en) * 1989-11-20 1991-11-13 Rhone-Poulenc Sante Heterocyclic derivatives, their preparation and pharmaceuticals containing them
FR2661177A1 (fr) * 1990-04-23 1991-10-25 Rhone Poulenc Sante Derives du naphtosultame antagonistes de la serotonine, leur preparation et les medicaments les contenant.
US5451579A (en) * 1994-02-15 1995-09-19 Merck & Co., Inc. 1-β-methyl-carbapenem, compositions containing same and methods of use

Also Published As

Publication number Publication date
HRP970213A2 (en) 1998-06-30
SK145498A3 (en) 1999-10-08
EA199800949A1 (ru) 1999-04-29
DE69727931T2 (de) 2005-04-14
PE64298A1 (es) 1998-10-30
EP0906313B1 (en) 2004-03-03
BG102949A (bg) 1999-10-29
SK283550B6 (sk) 2003-09-11
AU707459B2 (en) 1999-07-08
NO984949L (no) 1998-12-21
EP0906313A1 (en) 1999-04-07
IS4861A (is) 1998-10-06
JP3176068B2 (ja) 2001-06-11
AR006810A1 (es) 1999-09-29
ID16662A (id) 1997-10-30
PL186881B1 (pl) 2004-03-31
ES2216142T3 (es) 2004-10-16
ATE260915T1 (de) 2004-03-15
TW539677B (en) 2003-07-01
HUP9901778A3 (en) 2000-06-28
CA2252402A1 (en) 1997-10-30
NZ332183A (en) 2000-05-26
EA001296B1 (ru) 2000-12-25
WO1997040048A1 (en) 1997-10-30
PL329376A1 (en) 1999-03-29
JPH11508279A (ja) 1999-07-21
CN1074767C (zh) 2001-11-14
CN1222912A (zh) 1999-07-14
CA2252402C (en) 2002-12-24
EE9800355A (et) 1999-04-15
EE03689B1 (et) 2002-04-15
AU2462997A (en) 1997-11-12
CO4990968A1 (es) 2000-12-26
HUP9901778A2 (hu) 1999-09-28
DE69727931D1 (de) 2004-04-08
IL126480A0 (en) 1999-08-17
YU46298A (sh) 2000-03-21
KR20000010599A (ko) 2000-02-15
NO984949D0 (no) 1998-10-23
TR199802140T2 (xx) 1999-01-18
BR9708864A (pt) 1999-08-03
CZ340798A3 (cs) 1999-03-17

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20060421