HK1019704A1 - Process for manufacturing ophthalmic suspensions containing brinzolamide - Google Patents
Process for manufacturing ophthalmic suspensions containing brinzolamideInfo
- Publication number
- HK1019704A1 HK1019704A1 HK99104734A HK99104734A HK1019704A1 HK 1019704 A1 HK1019704 A1 HK 1019704A1 HK 99104734 A HK99104734 A HK 99104734A HK 99104734 A HK99104734 A HK 99104734A HK 1019704 A1 HK1019704 A1 HK 1019704A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- suspensions containing
- ophthalmic suspensions
- brinzolamide
- manufacturing ophthalmic
- containing brinzolamide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/77—Polymers containing oxygen of oxiranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3282096P | 1996-12-11 | 1996-12-11 | |
US08/886,933 US6071904A (en) | 1996-12-11 | 1997-07-02 | Process for manufacturing ophthalmic suspensions |
PCT/US1997/015727 WO1998025620A1 (fr) | 1996-12-11 | 1997-09-05 | Procede de fabrication de suspensions ophtalmiques |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1019704A1 true HK1019704A1 (en) | 2000-02-25 |
Family
ID=26708929
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK99104734A HK1019704A1 (en) | 1996-12-11 | 1999-10-23 | Process for manufacturing ophthalmic suspensions containing brinzolamide |
Country Status (14)
Country | Link |
---|---|
US (1) | US6071904A (fr) |
EP (1) | EP0941094B1 (fr) |
JP (1) | JP3611863B2 (fr) |
AT (1) | ATE209917T1 (fr) |
CA (1) | CA2274680C (fr) |
DE (2) | DE69708912T2 (fr) |
DK (1) | DK0941094T3 (fr) |
ES (1) | ES2169416T3 (fr) |
FR (1) | FR09C0022I2 (fr) |
HK (1) | HK1019704A1 (fr) |
LU (1) | LU91554I2 (fr) |
NL (1) | NL300388I2 (fr) |
PT (1) | PT941094E (fr) |
WO (1) | WO1998025620A1 (fr) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000001365A1 (fr) * | 1998-06-30 | 2000-01-13 | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) | Compositions ophtalmiques a liberation prolongee contenant une fluoroquinolone |
US7112588B2 (en) * | 2001-05-21 | 2006-09-26 | Alcon, Inc. | Use of proteasome inhibitors to treat dry eye disorders |
ES2278049T3 (es) | 2001-05-21 | 2007-08-01 | Alcon, Inc. | Uso de inhibidores de proteasoma para tratar trastornos de ojo seco. |
CN1239161C (zh) * | 2001-05-21 | 2006-02-01 | 爱尔康公司 | 可用于治疗干眼疾病的类固醇 |
US6872382B1 (en) | 2001-05-21 | 2005-03-29 | Alcon, Inc. | Use of selective PDE IV inhibitors to treat dry eye disorders |
AU2002309963B2 (en) | 2001-05-21 | 2007-03-01 | Alcon, Inc. | Use of NF-KAPPA-B inhibitors to treat dry eye disorders |
TWI298257B (en) | 2001-05-31 | 2008-07-01 | Allergan Inc | Hypotensive lipid and timolol compositions and methods of using same |
US6645994B1 (en) | 2001-06-01 | 2003-11-11 | Alcon, Inc. | Method of treating dry eye disorders |
ES2283756T3 (es) * | 2002-03-01 | 2007-11-01 | Novagali Pharma Sa | Sistemas autoemulsionantes de administracion de farmaco para taxoides. |
WO2004064828A1 (fr) | 2003-01-21 | 2004-08-05 | Senju Pharmaceutical Co., Ltd. | Preparation liquide aqueuse contenant de l'acide 2-amino-3-(4-bromobenzoyle) phenylacetique |
ATE497787T1 (de) * | 2004-03-12 | 2011-02-15 | Cipla Ltd | Sterilisationsprozess für steroide |
WO2008035246A2 (fr) * | 2006-07-28 | 2008-03-27 | Novagali Pharma Sa | Compositions contenant des composés ammonium quaternaire |
PT1891939E (pt) * | 2006-07-28 | 2013-10-07 | Novagali Pharma Sa | Composições contendo compostos de amónio quaternário |
TWI544927B (zh) | 2008-03-17 | 2016-08-11 | 愛爾康研究有限公司 | 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物 |
TWI489997B (zh) * | 2009-06-19 | 2015-07-01 | Alcon Res Ltd | 含有硼酸-多元醇錯合物之水性藥學組成物 |
WO2011067791A2 (fr) | 2009-12-03 | 2011-06-09 | Lupin Limited | Procédé d'élaboration de compositions ophtalmiques pharmaceutiques |
EP2394637A1 (fr) * | 2010-05-21 | 2011-12-14 | Zaklady Farmaceutyczne Polpharma SA | Procédé pour l'obtention de suspensions stériles de brinzolamide |
US9061034B2 (en) | 2010-07-29 | 2015-06-23 | Allergan, Inc. | Preservative free bimatoprost and timolol solutions |
ES2708451T3 (es) | 2010-07-29 | 2019-04-09 | Allergan Inc | Soluciones de bimatoprost y timolol sin conservantes |
WO2012053011A2 (fr) | 2010-10-18 | 2012-04-26 | Usv Limited | Compositions ophthalmiques comprenant de la brinzolamide |
WO2013025696A1 (fr) | 2011-08-15 | 2013-02-21 | Teva Pharmaceutical Industries Ltd. | Formulations ophtalmiques et leurs procédés de préparation |
EP2638909A1 (fr) | 2012-03-15 | 2013-09-18 | Azad Pharmaceutical Ingredients AG | Procédé de préparation stérile brinzolamide |
GR1007906B (el) | 2012-03-22 | 2013-05-30 | Φαρματεν Αβεε, | Οφθαλμικο φαρμακευτικο σκευασμα περιεχον ενα αναστολεα καρβονικης ανυδρασης και μεθοδος για την παρασκευη αυτου |
KR101966830B1 (ko) * | 2012-05-09 | 2019-04-08 | 아이크롬 에스피에이 | 무균 활성 약제 성분의 제조 방법 |
US20150119386A1 (en) * | 2012-05-21 | 2015-04-30 | Aurobindo Pharma Limited | Process for preparing opthalmic suspension of brinzolamide |
EP2906198B1 (fr) | 2012-10-11 | 2019-04-03 | Indoco Remedies Limited | Procédé de production d'une suspension ophtalmique stérile à base de la brinzolamide |
CN104721136A (zh) * | 2013-02-21 | 2015-06-24 | 四川大学 | 一种布佐林胺眼用纳米混悬剂及其制备方法 |
UA116273C2 (uk) * | 2013-10-17 | 2018-02-26 | Сентісс Фарма Прайвет Лімітед | Офтальмологічний фармацевтичний склад, що не містить консерванта |
US9820991B2 (en) * | 2013-11-08 | 2017-11-21 | Sentiss Pharma Private Limited | Pharmaceutical composition comprising brinzolamide |
US10463674B2 (en) | 2013-11-08 | 2019-11-05 | Sentiss Pharma Private Limited | Process for manufacturing sterile ophthalmic pharmaceutical suspensions |
ES2838756T3 (es) * | 2014-01-24 | 2021-07-02 | Sentiss Pharma Private Ltd | Composición farmacéutica que comprende brinzolamida |
PL407710A1 (pl) | 2014-03-28 | 2015-10-12 | Instytut Farmaceutyczny | Sposób wytwarzania preparatu kropli do oczu w postaci zawiesiny zawierającej brynzolamid i preparat wytworzony tym sposobem |
JP6279395B2 (ja) * | 2014-05-01 | 2018-02-14 | 東亜薬品株式会社 | ブリンゾラミド懸濁性点眼液組成物の製造方法 |
WO2016063184A1 (fr) | 2014-10-20 | 2016-04-28 | Sentiss Pharma Private Limited | Solution ophtalmique |
TWI664965B (zh) | 2015-06-22 | 2019-07-11 | 新源生物科技股份有限公司 | 酪胺酸激酶抑制劑之眼用調配物、其使用方法、及其製備方法 |
CN107582519A (zh) * | 2017-06-01 | 2018-01-16 | 合肥远志医药科技开发有限公司 | 一种布林佐胺滴眼液制剂及其制备方法 |
GR1009419B (el) | 2017-11-07 | 2018-12-14 | Φαρματεν Αβεε | Οφθαλμικο φαρμακευτικο σκευασμα που περιεχει εναν συνδυασμο βρινζολαμιδης και βριμονιδινης και μεθοδος για την παρασκευη αυτου |
JP2021521240A (ja) | 2018-04-25 | 2021-08-26 | シルパ メディケア リミテッドShilpa Medicare Limited | ブリンゾラミドの眼科用組成物 |
GR1009616B (el) * | 2018-07-20 | 2019-10-11 | Φαρματεν Α.Β.Ε.Ε. | Οφθαλμικο φαρμακευτικο σκευασμα που περιεχει βρινζολαμιδη και τιμολολη και μεθοδος παρασκευης αυτου |
WO2020240451A1 (fr) | 2019-05-29 | 2020-12-03 | Lupin Limited | Nanoémulsion gélifiante in situ de brinzolamide |
US11850249B2 (en) | 2020-10-05 | 2023-12-26 | Somerset Therapeutics, Llc | Methods of efficiently reducing intraocular pressure |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5378703A (en) * | 1990-04-09 | 1995-01-03 | Alcon Laboratories, Inc. | Sulfonamides useful as carbonic anhydrase inhibitors |
WO1992018124A1 (fr) * | 1991-04-17 | 1992-10-29 | Merck & Co., Inc. | COMPOSITIONS OPHTALMIQUES RENFERMANT DES COMBINAISONS D'UN INHIBITEUR D'ANHYDRASE CARBONIQUE ET D'UN ANTAGONISTE β-ADRENERGIQUE |
ATE169499T1 (de) * | 1992-02-21 | 1998-08-15 | Alcon Lab Inc | Topische antiglaukoma zusammensetzungen, enthaltend karbonhydrasehemmer und beta-blocker |
US5362758A (en) * | 1992-09-18 | 1994-11-08 | Pfizer Inc. | Ophthalmic piroxicam solution |
US5346702A (en) * | 1992-12-04 | 1994-09-13 | Sterling Winthrop Inc. | Use of non-ionic cloud point modifiers to minimize nanoparticle aggregation during sterilization |
US5429824A (en) * | 1992-12-15 | 1995-07-04 | Eastman Kodak Company | Use of tyloxapole as a nanoparticle stabilizer and dispersant |
US5576016A (en) * | 1993-05-18 | 1996-11-19 | Pharmos Corporation | Solid fat nanoemulsions as drug delivery vehicles |
US5422116A (en) * | 1994-02-18 | 1995-06-06 | Ciba-Geigy Corporation | Liquid ophthalmic sustained release delivery system |
-
1997
- 1997-07-02 US US08/886,933 patent/US6071904A/en not_active Expired - Lifetime
- 1997-09-05 DE DE69708912T patent/DE69708912T2/de not_active Expired - Lifetime
- 1997-09-05 ES ES97939835T patent/ES2169416T3/es not_active Expired - Lifetime
- 1997-09-05 CA CA002274680A patent/CA2274680C/fr not_active Expired - Lifetime
- 1997-09-05 DK DK97939835T patent/DK0941094T3/da active
- 1997-09-05 PT PT97939835T patent/PT941094E/pt unknown
- 1997-09-05 JP JP52598698A patent/JP3611863B2/ja not_active Expired - Lifetime
- 1997-09-05 EP EP97939835A patent/EP0941094B1/fr not_active Expired - Lifetime
- 1997-09-05 WO PCT/US1997/015727 patent/WO1998025620A1/fr active IP Right Grant
- 1997-09-05 DE DE122009000016C patent/DE122009000016I1/de active Pending
- 1997-09-05 AT AT97939835T patent/ATE209917T1/de active
-
1999
- 1999-10-23 HK HK99104734A patent/HK1019704A1/xx not_active IP Right Cessation
-
2009
- 2009-04-22 LU LU91554C patent/LU91554I2/fr unknown
- 2009-05-11 NL NL300388C patent/NL300388I2/nl unknown
- 2009-05-25 FR FR09C0022C patent/FR09C0022I2/fr active Active
Also Published As
Publication number | Publication date |
---|---|
PT941094E (pt) | 2002-05-31 |
DE122009000016I1 (de) | 2009-06-25 |
ATE209917T1 (de) | 2001-12-15 |
US6071904A (en) | 2000-06-06 |
CA2274680A1 (fr) | 1998-06-18 |
ES2169416T3 (es) | 2002-07-01 |
JP2000501749A (ja) | 2000-02-15 |
FR09C0022I2 (fr) | 2010-06-11 |
NL300388I1 (nl) | 2009-07-01 |
NL300388I2 (nl) | 2010-02-01 |
AU718079B2 (en) | 2000-04-06 |
AU4183897A (en) | 1998-07-03 |
EP0941094B1 (fr) | 2001-12-05 |
DK0941094T3 (da) | 2002-01-07 |
JP3611863B2 (ja) | 2005-01-19 |
EP0941094A1 (fr) | 1999-09-15 |
DE69708912T2 (de) | 2002-04-11 |
FR09C0022I1 (fr) | 2009-09-25 |
LU91554I2 (fr) | 2009-06-22 |
CA2274680C (fr) | 2003-11-18 |
DE69708912D1 (de) | 2002-01-17 |
WO1998025620A1 (fr) | 1998-06-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PE | Patent expired |
Effective date: 20170904 |