HK1015363A1 - Compounds analogous to thalidomide from the class comprising piperidine-2, 6-diones - Google Patents

Compounds analogous to thalidomide from the class comprising piperidine-2, 6-diones

Info

Publication number
HK1015363A1
HK1015363A1 HK99100272A HK99100272A HK1015363A1 HK 1015363 A1 HK1015363 A1 HK 1015363A1 HK 99100272 A HK99100272 A HK 99100272A HK 99100272 A HK99100272 A HK 99100272A HK 1015363 A1 HK1015363 A1 HK 1015363A1
Authority
HK
Hong Kong
Prior art keywords
diones
thalidomide
piperidine
class
compounds analogous
Prior art date
Application number
HK99100272A
Other languages
English (en)
Inventor
Oswald Zimmer
Werner Winter
Stephan Wnendt
Kai Zwingenberger
Kurt Eger
Uwe Teubert
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of HK1015363A1 publication Critical patent/HK1015363A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Indole Compounds (AREA)
HK99100272A 1997-02-01 1999-01-20 Compounds analogous to thalidomide from the class comprising piperidine-2, 6-diones HK1015363A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19703763A DE19703763C1 (de) 1997-02-01 1997-02-01 Thalidomidanaloge Verbindungen aus der Klasse der Piperidin-2,6-Dione

Publications (1)

Publication Number Publication Date
HK1015363A1 true HK1015363A1 (en) 1999-10-15

Family

ID=7819009

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99100272A HK1015363A1 (en) 1997-02-01 1999-01-20 Compounds analogous to thalidomide from the class comprising piperidine-2, 6-diones

Country Status (28)

Country Link
US (1) US6110941A (uk)
EP (1) EP0856513B1 (uk)
JP (1) JPH10316675A (uk)
KR (1) KR19980070959A (uk)
CN (1) CN1109032C (uk)
AR (1) AR010107A1 (uk)
AT (1) ATE311381T1 (uk)
AU (1) AU729733B2 (uk)
BR (1) BR9800253A (uk)
CA (1) CA2228385A1 (uk)
CO (1) CO4940441A1 (uk)
CZ (1) CZ27598A3 (uk)
DE (2) DE19703763C1 (uk)
DK (1) DK0856513T3 (uk)
ES (1) ES2253790T3 (uk)
HK (1) HK1015363A1 (uk)
HU (1) HUP9800146A3 (uk)
IL (1) IL122372A (uk)
NO (1) NO313007B1 (uk)
NZ (1) NZ329325A (uk)
PE (1) PE57499A1 (uk)
PL (1) PL188700B1 (uk)
RU (1) RU2184733C2 (uk)
SI (1) SI0856513T1 (uk)
SK (1) SK12498A3 (uk)
UA (1) UA45408C2 (uk)
UY (1) UY24870A1 (uk)
ZA (1) ZA98749B (uk)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10013499A1 (de) * 1998-09-24 2001-09-27 Gruenenthal Gmbh Substituierte Benzamide
DE10002509A1 (de) 2000-01-21 2001-07-26 Gruenenthal Gmbh Substituierte Glutarimide
US7320991B2 (en) 2001-02-27 2008-01-22 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, National Institutes Of Health Analogs of thalidomide as potential angiogenesis inhibitors
CN100398534C (zh) * 2003-09-15 2008-07-02 天津和美生物技术有限公司 合成酞胺哌啶酮及其衍生物的方法
CA2808646C (en) 2003-09-17 2016-08-23 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Thalidomide analogs as tnf-alpha modulators
US8952895B2 (en) 2011-06-03 2015-02-10 Apple Inc. Motion-based device operations
CA2648216C (en) * 2006-04-13 2016-06-07 Michael Gutschow Tetrahalogenated compounds useful as inhibitors of angiogenesis
WO2012031603A2 (en) 2010-09-09 2012-03-15 Danish Medical Consults Aps Airway administration of angiogenesis inhibitors
US8927725B2 (en) 2011-12-02 2015-01-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Thio compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5356906A (en) * 1989-10-27 1994-10-18 The Du Pont Merck Pharmaceutical Company (N-phthalimidoalkyl) piperidines useful as treatments for psychosis
WO1992014455A1 (en) * 1991-02-14 1992-09-03 The Rockefeller University METHOD FOR CONTROLLING ABNORMAL CONCENTRATION TNF α IN HUMAN TISSUES
EP0580641B1 (de) * 1991-04-17 1996-12-27 Grünenthal GmbH Neue thalidomidderivate, ein verfahren zu deren herstellung sowie die verwendung derselben in arzneimitteln
US5356406A (en) * 1993-01-08 1994-10-18 Steven Schraga Adaptor to facilitate interconnection of medicine bottle and syringe
US5463063A (en) * 1993-07-02 1995-10-31 Celgene Corporation Ring closure of N-phthaloylglutamines
US5698579A (en) * 1993-07-02 1997-12-16 Celgene Corporation Cyclic amides
EP0925294B3 (en) * 1996-07-24 2018-07-04 Celgene Corporation Substituted 2(2,6-dioxopiperidin-3-yl)phthalimides and -1-oxoisoindolines and method of reducing tnf-alpha levels

Also Published As

Publication number Publication date
AU729733B2 (en) 2001-02-08
AR010107A1 (es) 2000-05-17
ZA98749B (en) 1998-08-03
SK12498A3 (en) 1998-08-05
UY24870A1 (es) 2001-05-31
ES2253790T3 (es) 2006-06-01
CZ27598A3 (cs) 1998-08-12
US6110941A (en) 2000-08-29
HU9800146D0 (en) 1998-03-30
AU5284098A (en) 1998-08-06
NZ329325A (en) 1998-07-28
UA45408C2 (uk) 2002-04-15
JPH10316675A (ja) 1998-12-02
SI0856513T1 (sl) 2006-02-28
CN1109032C (zh) 2003-05-21
CA2228385A1 (en) 1998-08-01
HUP9800146A2 (hu) 1998-12-28
CN1190096A (zh) 1998-08-12
EP0856513A2 (de) 1998-08-05
HUP9800146A3 (en) 2000-06-28
NO980416D0 (no) 1998-01-30
IL122372A (en) 2002-12-01
RU2184733C2 (ru) 2002-07-10
PE57499A1 (es) 1999-07-10
NO313007B1 (no) 2002-07-29
DE19703763C1 (de) 1998-10-01
NO980416L (no) 1998-08-03
PL324588A1 (en) 1998-08-03
CO4940441A1 (es) 2000-07-24
DE59813233D1 (de) 2006-01-05
BR9800253A (pt) 1999-08-24
PL188700B1 (pl) 2005-03-31
KR19980070959A (ko) 1998-10-26
IL122372A0 (en) 1998-06-15
DK0856513T3 (da) 2005-12-27
EP0856513B1 (de) 2005-11-30
ATE311381T1 (de) 2005-12-15
EP0856513A3 (de) 1998-09-23

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20080204