HK1005033A1 - Stable solutions of rebeccamycin analog and preparation thereof - Google Patents

Stable solutions of rebeccamycin analog and preparation thereof Download PDF

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Publication number
HK1005033A1
HK1005033A1 HK98104205A HK98104205A HK1005033A1 HK 1005033 A1 HK1005033 A1 HK 1005033A1 HK 98104205 A HK98104205 A HK 98104205A HK 98104205 A HK98104205 A HK 98104205A HK 1005033 A1 HK1005033 A1 HK 1005033A1
Authority
HK
Hong Kong
Prior art keywords
acid
rebeccamycin
diethylaminoethyl
water
recited
Prior art date
Application number
HK98104205A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1005033B (en
Inventor
V. Venkataram Ubrani
K. Franchini Miriam
B. Bogardus Joseph
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of HK1005033B publication Critical patent/HK1005033B/en
Publication of HK1005033A1 publication Critical patent/HK1005033A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
HK98104205A 1989-05-10 1998-05-15 Stable solutions of rebeccamycin analog and preparation thereof HK1005033A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/349,608 US5496809A (en) 1989-05-10 1989-05-10 Stable solutions of rebeccamycin analog
US349608 1989-05-10

Publications (2)

Publication Number Publication Date
HK1005033B HK1005033B (en) 1998-12-18
HK1005033A1 true HK1005033A1 (en) 1998-12-18

Family

ID=23373191

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98104205A HK1005033A1 (en) 1989-05-10 1998-05-15 Stable solutions of rebeccamycin analog and preparation thereof

Country Status (25)

Country Link
US (1) US5496809A (cs)
EP (1) EP0397147B1 (cs)
JP (1) JPH0643437B2 (cs)
KR (1) KR920004098B1 (cs)
CN (1) CN1054510C (cs)
AT (1) ATE117313T1 (cs)
AU (1) AU618896B2 (cs)
CA (1) CA2015632C (cs)
CZ (1) CZ283416B6 (cs)
DE (1) DE69016087T2 (cs)
DK (1) DK0397147T3 (cs)
EG (1) EG19218A (cs)
ES (1) ES2066902T3 (cs)
FI (1) FI95777C (cs)
GR (1) GR3015714T3 (cs)
HK (1) HK1005033A1 (cs)
HU (1) HU206627B (cs)
IE (1) IE66515B1 (cs)
IL (1) IL94312A (cs)
NO (1) NO176390C (cs)
PT (1) PT93991B (cs)
RU (1) RU2053766C1 (cs)
TW (1) TW202390B (cs)
YU (1) YU90490A (cs)
ZA (1) ZA903535B (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993018766A1 (en) * 1992-03-20 1993-09-30 The Wellcome Foundation Limited Further indole derivatives with antiviral activity
US5968961A (en) * 1997-05-07 1999-10-19 Romark Laboratories, L.C. Pharmaceutical compositions of tizoxanide and nitazoxanide
WO1998019707A1 (en) * 1996-11-05 1998-05-14 Alcon Laboratories, Inc. Polyhydroxy monocarboxylic and dicarboxylic acids and their lactones in ophthalmic compositions
US20040048012A1 (en) * 1996-11-18 2004-03-11 Weder Donald E. Polymeric materials having a matte finish on a surface thereof
CA2241609C (en) * 1997-06-26 2009-08-25 Southpac Trust International, Inc. Polymeric material having a cloth-like appearance
RU2185819C1 (ru) * 2001-10-18 2002-07-27 Дорофеенко Алла Ивановна Средство, обладающее противоопухолевым действием
RU2203056C1 (ru) * 2002-06-18 2003-04-27 Нестерук Владимир Викторович Способ получения твердой лекарственной формы препарата на основе дибазола
CN100344285C (zh) * 2005-02-03 2007-10-24 宋艳 多潘立酮水溶性制剂及其制备方法
JP4822151B2 (ja) * 2005-02-14 2011-11-24 山本光学株式会社 眼鏡保持バンドおよびその保持バンド付き眼鏡

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4808613A (en) * 1986-11-21 1989-02-28 Bristol-Myers Company Rebeccamycin derivative containing pharmaceutical composition
US4785085A (en) * 1986-11-21 1988-11-15 Bristol-Myers Company Rebeccamycin analogs

Also Published As

Publication number Publication date
PT93991A (pt) 1991-02-08
EP0397147A2 (en) 1990-11-14
HUT54053A (en) 1991-01-28
HU206627B (en) 1992-12-28
CZ225590A3 (en) 1997-12-17
ES2066902T3 (es) 1995-03-16
IE66515B1 (en) 1996-01-10
EP0397147B1 (en) 1995-01-18
PT93991B (pt) 1996-11-29
IL94312A0 (en) 1991-03-10
NO902048D0 (no) 1990-05-09
RU2053766C1 (ru) 1996-02-10
JPH0643437B2 (ja) 1994-06-08
AU618896B2 (en) 1992-01-09
HU902989D0 (en) 1990-09-28
FI902276A0 (fi) 1990-05-07
CA2015632C (en) 1998-01-27
NO176390B (no) 1994-12-19
CN1047204A (zh) 1990-11-28
US5496809A (en) 1996-03-05
IL94312A (en) 1994-02-27
EP0397147A3 (en) 1991-06-12
IE901687L (en) 1990-11-10
ATE117313T1 (de) 1995-02-15
DK0397147T3 (da) 1995-03-20
JPH0317094A (ja) 1991-01-25
YU90490A (en) 1991-10-31
CN1054510C (zh) 2000-07-19
KR900017596A (ko) 1990-12-19
CZ283416B6 (cs) 1998-04-15
DE69016087D1 (de) 1995-03-02
GR3015714T3 (en) 1995-07-31
AU5482390A (en) 1990-11-15
FI95777B (fi) 1995-12-15
NO902048L (no) 1990-11-12
NO176390C (no) 1995-03-29
EG19218A (en) 1994-10-30
FI95777C (fi) 1996-03-25
ZA903535B (en) 1991-01-30
CA2015632A1 (en) 1990-11-10
DE69016087T2 (de) 1995-05-24
KR920004098B1 (ko) 1992-05-25
TW202390B (cs) 1993-03-21

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20070509