HK1001861A1 - Process for the crystallization from water of (s)-n,n'-bis(2-hydroxy-1-(hydroxymethyl)ethyl)-5-((2-hydroxy-1-oxopropyl)amino)-2,4,6-triiodo-1,3-benzendicarboxamide - Google Patents

Process for the crystallization from water of (s)-n,n'-bis(2-hydroxy-1-(hydroxymethyl)ethyl)-5-((2-hydroxy-1-oxopropyl)amino)-2,4,6-triiodo-1,3-benzendicarboxamide

Info

Publication number
HK1001861A1
HK1001861A1 HK98100990A HK98100990A HK1001861A1 HK 1001861 A1 HK1001861 A1 HK 1001861A1 HK 98100990 A HK98100990 A HK 98100990A HK 98100990 A HK98100990 A HK 98100990A HK 1001861 A1 HK1001861 A1 HK 1001861A1
Authority
HK
Hong Kong
Prior art keywords
hydroxy
benzendicarboxamide
triiodo
oxopropyl
hydroxymethyl
Prior art date
Application number
HK98100990A
Other languages
English (en)
Inventor
Marina Mauro
Original Assignee
Bracco Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT95RM000599 external-priority patent/IT1277934B1/it
Priority claimed from IT95RM000831 external-priority patent/IT1277950B1/it
Application filed by Bracco Int Bv filed Critical Bracco Int Bv
Publication of HK1001861A1 publication Critical patent/HK1001861A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK98100990A 1995-09-08 1998-02-10 Process for the crystallization from water of (s)-n,n'-bis(2-hydroxy-1-(hydroxymethyl)ethyl)-5-((2-hydroxy-1-oxopropyl)amino)-2,4,6-triiodo-1,3-benzendicarboxamide HK1001861A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT95RM000599 IT1277934B1 (it) 1995-09-08 1995-09-08 Processo per la cristallizzazione da acqua della s-n,n' -bis- ( 2-idrossi -1 -(idrossimetil) etil) -5- ((2 -idrossi -1- ossopropil)
IT95RM000831 IT1277950B1 (it) 1995-12-19 1995-12-19 Processo per la cristallizzazione da acqua della s-n,n'-bis (2-idrossi -1-(idrossimetil)etil)-5-((2-idrossi-1-ossopropil)ammino).2,4,6-
PCT/EP1996/003399 WO1997009300A1 (en) 1995-09-08 1996-08-02 Process for the crystallization from water of (s)-n,n'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-1,3-benzendicarboxamide

Publications (1)

Publication Number Publication Date
HK1001861A1 true HK1001861A1 (en) 1998-07-17

Family

ID=26332086

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98100990A HK1001861A1 (en) 1995-09-08 1998-02-10 Process for the crystallization from water of (s)-n,n'-bis(2-hydroxy-1-(hydroxymethyl)ethyl)-5-((2-hydroxy-1-oxopropyl)amino)-2,4,6-triiodo-1,3-benzendicarboxamide

Country Status (17)

Country Link
US (1) US5689002A (cs)
EP (1) EP0790979B1 (cs)
JP (1) JP4070235B2 (cs)
KR (1) KR100270411B1 (cs)
CN (1) CN1070843C (cs)
AT (1) ATE187437T1 (cs)
AU (1) AU708195B2 (cs)
BR (1) BR9606624A (cs)
CA (1) CA2204734C (cs)
CZ (1) CZ288645B6 (cs)
DE (1) DE69605528T2 (cs)
ES (1) ES2140887T3 (cs)
HK (1) HK1001861A1 (cs)
HU (1) HU220965B1 (cs)
NO (1) NO308841B1 (cs)
PL (1) PL184937B1 (cs)
WO (1) WO1997009300A1 (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT101720A (pt) * 1995-06-08 1997-01-31 Hovione Sociedade Quimica S A Processo para a purificacao e cristalizacao de iopamidol
KR20000031642A (ko) * 1998-11-09 2000-06-05 강재헌 이오파미돌의 결정화 방법
KR20050044506A (ko) * 2001-11-16 2005-05-12 랜박시 래보러터리스 리미티드 결정질 이미페넴의 제조 방법
CN100418945C (zh) * 2006-01-13 2008-09-17 江苏省原子医学研究所 一种碘昔兰的纯化方法
US20110021834A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As Continuous process of preparing intermediate for non-ionic x-ray contrast agents
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
EP3548461B1 (en) 2016-12-05 2021-02-03 Bracco Imaging SpA Mechanochemical synthesis of radiographic agents intermediates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH608189A5 (cs) * 1974-12-13 1978-12-29 Savac Ag
IL110391A (en) * 1993-07-30 1998-12-06 Zambon Spa Process for the formation of infamidol

Also Published As

Publication number Publication date
MX9703341A (es) 1997-07-31
EP0790979B1 (en) 1999-12-08
HUP9801837A3 (en) 2001-06-28
CN1070843C (zh) 2001-09-12
PL320027A1 (en) 1997-09-01
DE69605528T2 (de) 2000-05-04
NO971863D0 (no) 1997-04-23
DE69605528D1 (de) 2000-01-13
EP0790979A1 (en) 1997-08-27
KR970707073A (ko) 1997-12-01
WO1997009300A1 (en) 1997-03-13
US5689002A (en) 1997-11-18
ES2140887T3 (es) 2000-03-01
BR9606624A (pt) 1997-11-11
NO308841B1 (no) 2000-11-06
AU708195B2 (en) 1999-07-29
CA2204734C (en) 2009-12-29
PL184937B1 (pl) 2003-01-31
NO971863L (no) 1997-04-23
CZ288645B6 (cs) 2001-08-15
JPH10508878A (ja) 1998-09-02
AU6788896A (en) 1997-03-27
ATE187437T1 (de) 1999-12-15
CA2204734A1 (en) 1997-03-13
CN1164853A (zh) 1997-11-12
JP4070235B2 (ja) 2008-04-02
HUP9801837A2 (hu) 1998-12-28
KR100270411B1 (ko) 2000-11-01
HU220965B1 (hu) 2002-07-29
CZ138597A3 (cs) 1998-02-18

Similar Documents

Publication Publication Date Title
HK1001861A1 (en) Process for the crystallization from water of (s)-n,n'-bis(2-hydroxy-1-(hydroxymethyl)ethyl)-5-((2-hydroxy-1-oxopropyl)amino)-2,4,6-triiodo-1,3-benzendicarboxamide
EP0839056A4 (en) METHOD FOR PRODUCING IOVERSOL
EP0886634A4 (en) METHOD FOR PRODUCING IOVERSOL
IL123259A (en) Process for the purification of an intermediate in the preparation of iopamidol
PL352551A1 (en) C16 unsaturated analoques of prostaglandines selective in respect to fp
IT1303797B1 (it) Processo per la preparazione di n,n'-bis(2,3-diidrossipropil)-5-((idrossiacetil)metilammino)-2,4,6-triiodo-1,3-benzendicarbossammide.
ZA981070B (en) Process for the crystallization from a linear or branched (c5-c6) alcohol or their mixtures of (S)-N,N'-bis[2-hydroxy-1-(hydroxymethyl) ethyl]-5-[(2-hydroxy-1-oxopropyl)aminto]-2,4,6-triiodo-1,3-benzendicarboxamide
ITMI981996A0 (it) Processo per la preparazione della s-n,n'-bis[2-idrossi-1- (idrossimetil)etil]-5-[(2-idrossi-1-ossopropil)ammino]-2,4,6-triiodo-
ZA967504B (en) Process for the crystallization fromwater of (s)-n,n'-bis[2-hydroxy-1-(hydroxymethyl]-5-[(2-hydroxy-1-oxo-propyl)amino]-2,4,6-triiodo-1,3-benzendicarboxymide
IT1301667B (it) Procedimento per la purificazione del trimetilolpropano, particolarmente idoneo per produrre trimetilolpropano inodore
ITPD910207A1 (it) Processo per la sintesi e la purificazione di forme troncate del fattore neuronotrofico ciliare umano

Legal Events

Date Code Title Description
PF Patent in force
PE Patent expired

Effective date: 20160801