GT201200267A - Forma farmacéutica parenteral que libera inhibidores de aromatasa y gestágenos para el tratamiento de endometriosis - Google Patents
Forma farmacéutica parenteral que libera inhibidores de aromatasa y gestágenos para el tratamiento de endometriosisInfo
- Publication number
- GT201200267A GT201200267A GT201200267A GT201200267A GT201200267A GT 201200267 A GT201200267 A GT 201200267A GT 201200267 A GT201200267 A GT 201200267A GT 201200267 A GT201200267 A GT 201200267A GT 201200267 A GT201200267 A GT 201200267A
- Authority
- GT
- Guatemala
- Prior art keywords
- endometriosis
- treatment
- gestagen
- pharmaceutical form
- parenteral pharmaceutical
- Prior art date
Links
- 239000003886 aromatase inhibitor Substances 0.000 title abstract 3
- 201000009273 Endometriosis Diseases 0.000 title abstract 2
- 102000014654 Aromatase Human genes 0.000 title 1
- 108010078554 Aromatase Proteins 0.000 title 1
- 239000003418 antiprogestin Substances 0.000 title 1
- 230000000694 effects Effects 0.000 abstract 3
- 229940122815 Aromatase inhibitor Drugs 0.000 abstract 2
- 230000015556 catabolic process Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003433 contraceptive agent Substances 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 230000004899 motility Effects 0.000 abstract 1
- 230000002611 ovarian Effects 0.000 abstract 1
- 239000000583 progesterone congener Substances 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
EL OBJETO DE LA PRESENTE INVENCIÓN PARA EL TRATAMIENTO DE LA ENDOMETRIOSIS ES LA PROVISIÓN DE UNA FORMA FARMACÉUTICA PARENTERAL (SISTEMA DE LIBERACIÓN) PARA LA LIBERACIÓN CONTROLADA DE UN INHIBIDOR DE AROMATASA (AI) CON UNA VELOCIDAD DE LIBERACIÓN DIARIA QUE NO INDUCE NINGUNA ESTIMULACIÓN DE LOS OVARIOS POR NEGATIVA RETROALIMENTACIÓN DEL EJE HIPOFISARIO-OVÁRICO (QUE PODRÍA INDUCIR LA SECRECIÓN DE GONADOTROPINAS Y LA ESTIMULACIÓN DE CRECIMIENTO FOLICULAR OVÁRICO), Y DE UN AGENTE GESTÁGENO CON UNA VELOCIDAD DE LIBERACIÓN DIARIA DE DEBAJO DE LA DOSIS INHIBIDORA DE LA OVULACIÓN-, QUE PROPORCIONA UN EFECTO ANTICONCEPTIVO BASADO EN LOCALES EFECTOS (POR EJEMPLO, LA REDUCCIÓN Y EL ENGROSAMIENTO DEL MOCO CERVICAL PARA EVITAR EL ASCENSO DE LOS ESPERMATOZOIDES, EFECTOS SOBRE EL ENDOMETRIO Y EN LA MOTILIDAD TUBÁRICA CON EL FIN DE OBSTACULIZAR LA IMPLANTACIÓN Y EL TRANSPORTE DE ÓVULOS).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102010003494A DE102010003494A1 (de) | 2010-03-31 | 2010-03-31 | Parenterales Abgabesystem, das Aromatasehemmer und Gestagene freisetzt, für die Behandlung von Endometriose |
Publications (1)
Publication Number | Publication Date |
---|---|
GT201200267A true GT201200267A (es) | 2014-06-04 |
Family
ID=44021822
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GT201200267A GT201200267A (es) | 2010-03-31 | 2012-09-28 | Forma farmacéutica parenteral que libera inhibidores de aromatasa y gestágenos para el tratamiento de endometriosis |
Country Status (41)
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
PT2782584T (pt) | 2011-11-23 | 2021-09-02 | Therapeuticsmd Inc | Preparações e terapias de substituição para hormonoterapias naturais combinadas |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
CA2987323A1 (en) * | 2015-05-27 | 2016-12-01 | Quest Diagnostics Investments Llc | Methods for mass spectrometric quantitation of analytes extracted from a microsampling device |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
JP6936801B2 (ja) * | 2015-12-21 | 2021-09-22 | バイエル・オーイュー | 薬剤送達装置の製造方法およびその方法に従って製造された薬剤送達装置 |
CA3020153A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
GB201614179D0 (en) * | 2016-08-19 | 2016-10-05 | Mereo Biopharma 2 Ltd | Dosage regimen for the treatment of endometriosis |
CN109248166A (zh) * | 2017-07-13 | 2019-01-22 | 国家卫生计生委科学技术研究所 | 阿那曲唑储库型阴道环的制备及应用 |
US10918649B2 (en) | 2019-06-21 | 2021-02-16 | The Population Council, Inc. | System for providing birth control |
US20240122885A1 (en) * | 2021-02-12 | 2024-04-18 | The Regents Of The University Of California | Endometriosis-Related Methods and Compositions |
CN115804762B (zh) * | 2022-12-20 | 2024-05-31 | 浙江大学 | 一种巨噬细胞膜包覆的异位子宫内膜靶向纳米粒、制备方法及应用 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8517360D0 (en) * | 1985-07-09 | 1985-08-14 | Erba Farmitalia | Substituted androsta-1,4-diene-3,17-diones |
JP2602456B2 (ja) * | 1990-04-12 | 1997-04-23 | 雪印乳業株式会社 | 子宮内膜症治療剤 |
FI95768C (fi) * | 1993-06-17 | 1996-03-25 | Leiras Oy | Emättimensisäinen antosysteemi |
US7744916B2 (en) * | 1997-06-11 | 2010-06-29 | Umd, Inc. | Coated vaginal device for delivery of anti-migraine and anti-nausea drugs |
FI20000572A (fi) * | 2000-03-13 | 2001-09-14 | Leiras Oy | Implantaattien asettamiseen tarkoitettu laite |
PT1377298E (pt) * | 2001-01-26 | 2006-12-29 | Pharmacia & Upjohn Co Llc | Exemestano para o tratamento de perturbações hormono-dependentes. |
GB0120147D0 (en) * | 2001-08-17 | 2001-10-10 | Metris Therapeutics Ltd | Treatment method |
WO2003017973A1 (en) | 2001-08-31 | 2003-03-06 | Pantarhei Bioscience B.V. | A method of treating benign gynaecological disorders and a drug delivery vehicle for use in such a method |
GB0302572D0 (en) * | 2003-02-05 | 2003-03-12 | Astrazeneca Ab | Method of treatment |
GB0320238D0 (en) * | 2003-08-29 | 2003-10-01 | Medical Res Council | Treatment of disease |
US20050101579A1 (en) * | 2003-11-06 | 2005-05-12 | Shippen Eugene R. | Endometriosis treatment protocol |
TW200930343A (en) * | 2007-09-21 | 2009-07-16 | Organon Nv | Drug delivery system |
TW200927141A (en) * | 2007-11-22 | 2009-07-01 | Bayer Schering Pharma Oy | Vaginal delivery system |
US20110033519A1 (en) * | 2009-08-07 | 2011-02-10 | Leong Madeline | Device with Aromatase Inhibitor for the Treatment and Prevention of Uterine Fibroids and Method of Use |
-
2010
- 2010-03-31 DE DE102010003494A patent/DE102010003494A1/de not_active Withdrawn
-
2011
- 2011-03-28 PE PE2012001815A patent/PE20130524A1/es not_active Application Discontinuation
- 2011-03-28 UA UAA201212231A patent/UA109655C2/uk unknown
- 2011-03-28 MA MA35266A patent/MA34099B1/fr unknown
- 2011-03-28 WO PCT/EP2011/054737 patent/WO2011120925A1/de active Application Filing
- 2011-03-28 CA CA2794790A patent/CA2794790A1/en not_active Abandoned
- 2011-03-28 MX MX2012011329A patent/MX2012011329A/es active IP Right Grant
- 2011-03-28 PL PL11714245T patent/PL2552404T3/pl unknown
- 2011-03-28 EP EP11714245.5A patent/EP2552404B1/de active Active
- 2011-03-28 CN CN201180017806.6A patent/CN103002873B/zh not_active Expired - Fee Related
- 2011-03-28 RS RS20150188A patent/RS53876B1/en unknown
- 2011-03-28 NZ NZ602698A patent/NZ602698A/en not_active IP Right Cessation
- 2011-03-28 US US13/638,243 patent/US20130131027A1/en not_active Abandoned
- 2011-03-28 JP JP2013501792A patent/JP6012048B2/ja not_active Expired - Fee Related
- 2011-03-28 KR KR1020127025671A patent/KR20130010047A/ko not_active Application Discontinuation
- 2011-03-28 ES ES11714245.5T patent/ES2533101T3/es active Active
- 2011-03-28 DK DK11714245.5T patent/DK2552404T3/en active
- 2011-03-28 PT PT11714245T patent/PT2552404E/pt unknown
- 2011-03-28 ME MEP-2015-39A patent/ME02159B/me unknown
- 2011-03-28 BR BR112012024739A patent/BR112012024739A2/pt not_active IP Right Cessation
- 2011-03-28 MY MYPI2012004360A patent/MY160353A/en unknown
- 2011-03-28 SI SI201130435T patent/SI2552404T1/sl unknown
- 2011-03-28 EA EA201201358A patent/EA025582B1/ru not_active IP Right Cessation
- 2011-03-28 AU AU2011234587A patent/AU2011234587B2/en not_active Ceased
- 2011-03-28 SG SG2012068847A patent/SG184111A1/en unknown
- 2011-03-30 TW TW105118443A patent/TW201632184A/zh unknown
- 2011-03-30 TW TW100111100A patent/TWI576107B/zh not_active IP Right Cessation
- 2011-03-30 AR ARP110101037A patent/AR080861A1/es unknown
- 2011-03-30 UY UY0001033303A patent/UY33303A/es not_active Application Discontinuation
-
2012
- 2012-09-13 ZA ZA2012/06869A patent/ZA201206869B/en unknown
- 2012-09-23 IL IL222056A patent/IL222056A/en not_active IP Right Cessation
- 2012-09-24 EC ECSP12012176 patent/ECSP12012176A/es unknown
- 2012-09-27 CR CR20120493A patent/CR20120493A/es unknown
- 2012-09-27 TN TNP2012000468A patent/TN2012000468A1/en unknown
- 2012-09-28 CU CU2012000145A patent/CU20120145A7/es unknown
- 2012-09-28 DO DO2012000255A patent/DOP2012000255A/es unknown
- 2012-09-28 GT GT201200267A patent/GT201200267A/es unknown
- 2012-09-28 CL CL2012002722A patent/CL2012002722A1/es unknown
- 2012-09-28 CO CO12170798A patent/CO6630125A2/es unknown
-
2013
- 2013-06-13 HK HK13106968.0A patent/HK1179531A1/xx not_active IP Right Cessation
-
2015
- 2015-03-16 HR HRP20150294TT patent/HRP20150294T1/hr unknown
- 2015-03-17 CY CY20151100269T patent/CY1116187T1/el unknown
- 2015-06-18 US US14/743,935 patent/US20150359802A1/en not_active Abandoned
-
2016
- 2016-06-09 JP JP2016115248A patent/JP2016164200A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GT201200267A (es) | Forma farmacéutica parenteral que libera inhibidores de aromatasa y gestágenos para el tratamiento de endometriosis | |
IL267681A (en) | Selective grp94 inhibitors and their uses | |
HK1214873A1 (zh) | 對品牌名稱和域名進行保護的設備、系統以及方法 | |
DOP2015000227A (es) | Virus de la enfermedad de newcastle y usos de los mismos | |
EP2943198A4 (en) | INHIBITORS OF 3- (BENZOIMIDAZOL-2-YL) -INDAZOLE OF THE WNT SIGNALING PATHWAY AND THERAPEUTIC USES THEREOF | |
CR20160308A (es) | Combinaciones de inhibidores de histona deacetilasa y farmacos inmunomoduladores | |
PE20142239A1 (es) | Sistemas intrauterinos, dispositivos de insercion diu, y metodos relacionados y kits de los mismos | |
BR112016002674A2 (pt) | dispositivo eletrônico e método para proporcionar conteúdo de acordo com campo de atributo | |
BR112015019099A2 (pt) | Método implementado por computador para gerar uma pilha de chamadas assíncronas e sistema de computador | |
CL2015002733A1 (es) | Composición farmacéutica de clorhidrato de s-cetamina. | |
ECSP13012844A (es) | Composición efervescente en forma sólida para uso en aplicaciones vaginales para el tratamiento de infecciones vaginales | |
BR112015003094A8 (pt) | dispositivo contraceptivo intrauterino | |
CL2016003295A1 (es) | Dosificación intermitente de un inhibidor de mdm2. | |
PH12016500895B1 (en) | Substituted piperidyl-ethyl-pyrimidine as ghrelin o-acyl transferase inhibitor | |
AR098129A1 (es) | Preparación y administración de soluciones de liberación sostenida de óxido nítrico | |
BR112016011638A2 (pt) | composição dispersável em água, artigo moldado, e, método para formar uma peça moldada por injeção | |
CL2015001448A1 (es) | Método para sincronización del tiempo de inseminación en cerdas jovenes | |
CU20160051A7 (es) | Sistema de administración intrauterina | |
CL2015002181A1 (es) | Tratamiento de formas progresivas de esclerosis múltiple con laquinimod. | |
BR112015022513A2 (pt) | produto e método para tratamento de diarreia | |
CL2015003433A1 (es) | Derivados de tilosina y método para su preparación | |
CO2018005184A2 (es) | Aditivo para tratamiento posterior interno de composiciones aglutinantes minerales | |
CL2016000951A1 (es) | Forma cristalina anhidra h de cabazitaxel; proceso de preparación; composición farmacéutica que la comprende; útil para tratar cáncer. | |
CL2015001920A1 (es) | Formulaciones de lorazepam de liberación sostenida | |
TN2015000511A1 (en) | Pharmaceutical composition and the use thereof, and application regime of said pharmaceutical composition for on-demand contraception |