GT200700053A - Compuestos terapeuticos - Google Patents
Compuestos terapeuticosInfo
- Publication number
- GT200700053A GT200700053A GT200700053A GT200700053A GT200700053A GT 200700053 A GT200700053 A GT 200700053A GT 200700053 A GT200700053 A GT 200700053A GT 200700053 A GT200700053 A GT 200700053A GT 200700053 A GT200700053 A GT 200700053A
- Authority
- GT
- Guatemala
- Prior art keywords
- compounds
- concentration
- therapeutic compounds
- plamatic
- pharmacratic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A COMPUESTOS DE LA FORMULA GENERAL I EN LA QUE R1,R2,R3,R4,R5,R6,R7,R8,R19,R20, SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. ESTOS COMPUESTOS VAN A MANTENER NIVELES DE CONCENTRACION PLAMATICOS ADECUADOS A DIFERENCIA DE OTROS QUE POR LA ACCION DEL SISTEMA ENZIMATICO DEL CITOCROMO P450 QUE ES RESPONSABLE POR LA BIOTRANSFORMACION DE MEDICAMENTOS DISMINUYE LAS CONCENTRACIONES PLASMATICAS DEL FARMACO PRODUCIENDO CONCENTRACIONES SUBTERAPEUTICAS DURANTE EL TIEMPO DE PERMANENCIA DEL FARMACO Y POR LO ANTERIOR SON DE UTILIDAD EN CUADROS DE INFECCIONES VIRALES TALES COMO LAS INFECCIONES DEL VIRUS DE INMUNODEFICIENCIA HUMANA (VIH). T2007
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80659606P | 2006-07-05 | 2006-07-05 | |
US91098807P | 2007-04-10 | 2007-04-10 | |
US94180807P | 2007-06-04 | 2007-06-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
GT200700053A true GT200700053A (es) | 2009-08-03 |
Family
ID=38515807
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GT200700053A GT200700053A (es) | 2006-07-05 | 2007-07-04 | Compuestos terapeuticos |
Country Status (24)
Country | Link |
---|---|
US (1) | US7919488B2 (es) |
EP (1) | EP2046774A1 (es) |
KR (1) | KR20090034958A (es) |
CN (1) | CN101511812A (es) |
AP (1) | AP2009004763A0 (es) |
AR (1) | AR062154A1 (es) |
AU (1) | AU2007270814B2 (es) |
CA (1) | CA2660031A1 (es) |
CO (1) | CO6150178A2 (es) |
CR (1) | CR10573A (es) |
EA (1) | EA200900135A1 (es) |
GT (1) | GT200700053A (es) |
IL (1) | IL196490A0 (es) |
MA (1) | MA30629B1 (es) |
MX (1) | MX2009000482A (es) |
NO (1) | NO20090346L (es) |
NZ (1) | NZ574207A (es) |
PE (1) | PE20080998A1 (es) |
RS (1) | RS20090036A (es) |
TN (1) | TN2009000033A1 (es) |
TW (1) | TWI334867B (es) |
UY (1) | UY30460A1 (es) |
WO (1) | WO2008004096A1 (es) |
ZA (1) | ZA200900478B (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101534824A (zh) * | 2006-11-17 | 2009-09-16 | 艾博特公司 | 作为化学活素受体拮抗剂的氨基吡咯烷 |
CA2680360A1 (en) * | 2007-03-13 | 2008-09-18 | Arete Therapeutics, Inc. | 4-piperidinylurea compounds as soluble epoxide hydrolase inhibitors |
JP2011512359A (ja) | 2008-02-14 | 2011-04-21 | アミラ ファーマシューティカルズ,インク. | プロスタグランジンd2受容体のアンタゴニストとしての環式ジアリールエーテル化合物 |
US8426449B2 (en) | 2008-04-02 | 2013-04-23 | Panmira Pharmaceuticals, Llc | Aminoalkylphenyl antagonists of prostaglandin D2 receptors |
DE102008057343A1 (de) | 2008-11-14 | 2010-05-20 | Bayer Schering Pharma Aktiengesellschaft | Heterocyclisch substituierte Aryl-Verbindungen und ihre Verwendung |
DE102009041242A1 (de) | 2009-09-11 | 2011-12-15 | Bayer Schering Pharma Aktiengesellschaft | Heterocyclisch substituierte Aryl-Verbindungen und ihre Verwendung |
DE102008057344A1 (de) | 2008-11-14 | 2010-05-20 | Bayer Schering Pharma Aktiengesellschaft | Aminoalkyl-substituierte Aryl-Verbindungen und ihre Verwendung |
DE102009041241A1 (de) | 2009-09-11 | 2011-08-04 | Bayer Schering Pharma Aktiengesellschaft, 13353 | Substituierte Aryl-Verbindungen und ihre Verwendung |
DE102008057364A1 (de) | 2008-11-14 | 2010-05-20 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Aryl-Verbindungen und ihre Verwendung |
WO2010057118A2 (en) | 2008-11-17 | 2010-05-20 | Amira Pharmaceuticals, Inc. | Heterocyclic antagonists of prostaglandin d2 receptors |
MX2012015252A (es) | 2010-06-30 | 2013-05-30 | Ironwood Pharmaceuticals Inc | Estimuladores de sgc. |
CN107266433A (zh) | 2010-11-09 | 2017-10-20 | 铁木医药有限公司 | sGC刺激剂 |
CN104066731B (zh) | 2011-12-27 | 2016-06-15 | 铁木医药有限公司 | 可用作sgc刺激剂的2-苄基、3-(嘧啶-2-基)取代的吡唑类 |
WO2014000178A1 (en) | 2012-06-27 | 2014-01-03 | Merck Sharp & Dohme Corp. | Sulfonamide derivatives and methods of use thereof for improving the pharmacokinetics of a drug |
CN104540813A (zh) * | 2012-06-27 | 2015-04-22 | 默沙东公司 | 磺酰胺衍生物以及使用它们用于改善药物的药物动力学的方法 |
WO2014194519A1 (en) * | 2013-06-07 | 2014-12-11 | Merck Sharp & Dohme Corp. | Imidazole derivatives and methods of use thereof for improving pharmacokinetics of drug |
WO2015070367A1 (en) | 2013-11-12 | 2015-05-21 | Merck Sharp & Dohme Corp. | Piperidine or piperazine linked imidazole and triazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug |
WO2015070366A1 (en) * | 2013-11-12 | 2015-05-21 | Merck Sharp & Dohme Corp. | Aryl linked imidazole and triazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug |
WO2020163689A1 (en) * | 2019-02-08 | 2020-08-13 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | 20-hete formation inhibitors |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0024795D0 (en) | 2000-10-10 | 2000-11-22 | Hoffmann La Roche | Pyrazole derivatives for the treatment of viral diseases |
DE60201740T2 (de) * | 2001-04-05 | 2005-11-03 | Torrent Pharmaceuticals Ltd., Ahmedabad | Heterocyclische verbindungen für alterungs und diabetes bedingte vasculare erkrankungen |
US7008953B2 (en) * | 2003-07-30 | 2006-03-07 | Agouron Pharmaceuticals, Inc. | 3, 5 Disubstituted indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation |
US7662844B2 (en) * | 2004-07-12 | 2010-02-16 | Osi Pharmaceuticals, Inc. | Naphthylene derivatives as cytochrome P450 inhibitors |
EA014329B1 (ru) | 2005-09-23 | 2010-10-29 | Пфайзер Продактс Инк. | Пиридинаминосульфонилзамещенные бензамиды в качестве ингибиторов цитохрома р450 3а4 (cyp3a4) |
-
2007
- 2007-06-25 MX MX2009000482A patent/MX2009000482A/es not_active Application Discontinuation
- 2007-06-25 CA CA002660031A patent/CA2660031A1/en not_active Abandoned
- 2007-06-25 CN CNA200780032889XA patent/CN101511812A/zh active Pending
- 2007-06-25 NZ NZ574207A patent/NZ574207A/en not_active IP Right Cessation
- 2007-06-25 KR KR1020097002315A patent/KR20090034958A/ko not_active Application Discontinuation
- 2007-06-25 WO PCT/IB2007/001878 patent/WO2008004096A1/en active Application Filing
- 2007-06-25 AP AP2009004763A patent/AP2009004763A0/xx unknown
- 2007-06-25 RS RSP-2009/0036A patent/RS20090036A/sr unknown
- 2007-06-25 EP EP07734950A patent/EP2046774A1/en not_active Withdrawn
- 2007-06-25 AU AU2007270814A patent/AU2007270814B2/en not_active Ceased
- 2007-06-25 EA EA200900135A patent/EA200900135A1/ru unknown
- 2007-06-28 US US11/770,698 patent/US7919488B2/en not_active Expired - Fee Related
- 2007-07-03 AR ARP070102977A patent/AR062154A1/es not_active Application Discontinuation
- 2007-07-04 TW TW096124262A patent/TWI334867B/zh not_active IP Right Cessation
- 2007-07-04 UY UY30460A patent/UY30460A1/es unknown
- 2007-07-04 GT GT200700053A patent/GT200700053A/es unknown
- 2007-07-04 PE PE2007000860A patent/PE20080998A1/es not_active Application Discontinuation
-
2009
- 2009-01-13 IL IL196490A patent/IL196490A0/en unknown
- 2009-01-20 CR CR10573A patent/CR10573A/es unknown
- 2009-01-21 ZA ZA200900478A patent/ZA200900478B/xx unknown
- 2009-01-22 NO NO20090346A patent/NO20090346L/no not_active Application Discontinuation
- 2009-01-30 TN TN2009000033A patent/TN2009000033A1/fr unknown
- 2009-02-04 CO CO09010549A patent/CO6150178A2/es unknown
- 2009-02-05 MA MA31618A patent/MA30629B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
US7919488B2 (en) | 2011-04-05 |
UY30460A1 (es) | 2008-02-29 |
AU2007270814A1 (en) | 2008-01-10 |
AR062154A1 (es) | 2008-10-22 |
TW200811159A (en) | 2008-03-01 |
WO2008004096A1 (en) | 2008-01-10 |
CO6150178A2 (es) | 2010-04-20 |
CN101511812A (zh) | 2009-08-19 |
AP2009004763A0 (en) | 2009-02-28 |
NZ574207A (en) | 2010-10-29 |
NO20090346L (no) | 2009-02-19 |
EP2046774A1 (en) | 2009-04-15 |
RS20090036A (en) | 2010-06-30 |
TN2009000033A1 (fr) | 2010-08-19 |
MA30629B1 (fr) | 2009-08-03 |
CA2660031A1 (en) | 2008-01-10 |
ZA200900478B (en) | 2010-04-28 |
MX2009000482A (es) | 2009-01-27 |
TWI334867B (en) | 2010-12-21 |
IL196490A0 (en) | 2011-07-31 |
PE20080998A1 (es) | 2008-08-15 |
AU2007270814B2 (en) | 2011-07-14 |
CR10573A (es) | 2009-02-12 |
KR20090034958A (ko) | 2009-04-08 |
US20080021011A1 (en) | 2008-01-24 |
EA200900135A1 (ru) | 2009-06-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GT200700053A (es) | Compuestos terapeuticos | |
ECSP11010804A (es) | Compuestos orgánicos | |
CO2018002060A2 (es) | Compuestos farmacéuticos | |
PE20091756A1 (es) | Derivados de pirazolopirimidinona como moduladores de la pde9a | |
CL2013002299A1 (es) | Compuestos derivados de heterociclos, inhibidores de la replicacion del virus de la hepatitis c; composicion farmaceutica que los comprende; util en el tratamiento de una infeccion por vhc. (divisional solicitud 689-2011). | |
CR10250A (es) | Derivados de amida y su aplicación para el tratamiento de enfermedades relacionadas con proteína-g | |
NI201200012A (es) | Profármacos que comprenden un conjugado de insulina - conector | |
CO6361937A2 (es) | Derivados de heteroaril amidas y sus usos como activadores de glucoquinasa | |
NI201200089A (es) | INHIBIDORES DE N1 - PIRAZOLOESPIROCETONA ACETIL - CoA CARBOXILASA. | |
ECSP11011470A (es) | Nuevos derivados de pirimidina y sus usos en el tratamiento del cáncer y otras enfermedades | |
CL2016002348A1 (es) | Agonistas del receptor muscarínico | |
ECSP13013048A (es) | Spiro-[1,3]-oxacinas y spiro-[1,4]-oxacepinas como inhibidores | |
CR9463A (es) | Pirrolinas sustituidas, composiciones que las contienen, proceso de fabricacion y utilizacion | |
GT200900175A (es) | Derivados de ester y amida de indazolilo para el tratamiento de enfermedades mediadas por un receptor de glucocorticoides | |
PA8733401A1 (es) | Compuestos de pirro[1,2-b]piridazinona | |
CO6270324A2 (es) | Derivados de pirimidina para el tratamiento del asma epoc rinitis conjutivitis alergica dermatitis atopica cancer hepatitis b hepatitis c vih vph infecciones bacterianas y dermatosis | |
CO6470866A2 (es) | Enantiómeros de compuestos de espirooxindol y sus usos como agentes terapéuticos. | |
DOP2011000135A (es) | Moduladores de aril metil benzoquinazolinona alostericos positivos del receptor m1 | |
CU24117B1 (es) | Derivados de la piridina de tieno (2,3-b) como inhibidores virales de la réplica | |
CR10948A (es) | Compuestos triciclicos, composiciones y procedimientos | |
BR112012008518A2 (pt) | derivado heterocíclico, e, composição farmacêutica | |
CR10614A (es) | Derivados heterociclicos fusionados y metodos de uso | |
UY29827A1 (es) | 2-amina-pirimidina-4-(2-metil-1-(tetrahidro-2h-piran-4-il)-1-imidazol-5-y1) sustituidas y sus derivados, composiciones farmacéuticas que las contienen, procesos para su preparación y aplicaciones | |
CO6501188A2 (es) | Moduladores de piranil aril metil benzoquinazolina alostéricos positivos del receptos m1 | |
PE20161379A1 (es) | Nuevos compuestos macrociclicos |