ZA200900478B - Pyrazole derivatives as cytochrome P450 inhibitors - Google Patents
Pyrazole derivatives as cytochrome P450 inhibitorsInfo
- Publication number
- ZA200900478B ZA200900478B ZA200900478A ZA200900478A ZA200900478B ZA 200900478 B ZA200900478 B ZA 200900478B ZA 200900478 A ZA200900478 A ZA 200900478A ZA 200900478 A ZA200900478 A ZA 200900478A ZA 200900478 B ZA200900478 B ZA 200900478B
- Authority
- ZA
- South Africa
- Prior art keywords
- cytochrome
- inhibitors
- pyrazole derivatives
- pyrazole
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80659606P | 2006-07-05 | 2006-07-05 | |
| US91098807P | 2007-04-10 | 2007-04-10 | |
| US94180807P | 2007-06-04 | 2007-06-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200900478B true ZA200900478B (en) | 2010-04-28 |
Family
ID=38515807
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200900478A ZA200900478B (en) | 2006-07-05 | 2009-01-21 | Pyrazole derivatives as cytochrome P450 inhibitors |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US7919488B2 (es) |
| EP (1) | EP2046774A1 (es) |
| KR (1) | KR20090034958A (es) |
| CN (1) | CN101511812A (es) |
| AP (1) | AP2009004763A0 (es) |
| AR (1) | AR062154A1 (es) |
| AU (1) | AU2007270814B2 (es) |
| CA (1) | CA2660031A1 (es) |
| CO (1) | CO6150178A2 (es) |
| CR (1) | CR10573A (es) |
| EA (1) | EA200900135A1 (es) |
| GT (1) | GT200700053A (es) |
| IL (1) | IL196490A0 (es) |
| MA (1) | MA30629B1 (es) |
| MX (1) | MX2009000482A (es) |
| NO (1) | NO20090346L (es) |
| NZ (1) | NZ574207A (es) |
| PE (1) | PE20080998A1 (es) |
| RS (1) | RS20090036A (es) |
| TN (1) | TN2009000033A1 (es) |
| TW (1) | TWI334867B (es) |
| UY (1) | UY30460A1 (es) |
| WO (1) | WO2008004096A1 (es) |
| ZA (1) | ZA200900478B (es) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8754107B2 (en) * | 2006-11-17 | 2014-06-17 | Abbvie Inc. | Aminopyrrolidines as chemokine receptor antagonists |
| AU2007349176A1 (en) * | 2007-03-13 | 2008-09-18 | Arete Therapeutics, Inc. | 4-piperidinylurea compounds as soluble epoxide hydrolase inhibitors |
| JP2011512359A (ja) | 2008-02-14 | 2011-04-21 | アミラ ファーマシューティカルズ，インク． | プロスタグランジンｄ２受容体のアンタゴニストとしての環式ジアリールエーテル化合物 |
| US8426449B2 (en) | 2008-04-02 | 2013-04-23 | Panmira Pharmaceuticals, Llc | Aminoalkylphenyl antagonists of prostaglandin D2 receptors |
| DE102008057344A1 (de) | 2008-11-14 | 2010-05-20 | Bayer Schering Pharma Aktiengesellschaft | Aminoalkyl-substituierte Aryl-Verbindungen und ihre Verwendung |
| DE102008057364A1 (de) | 2008-11-14 | 2010-05-20 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Aryl-Verbindungen und ihre Verwendung |
| DE102008057343A1 (de) | 2008-11-14 | 2010-05-20 | Bayer Schering Pharma Aktiengesellschaft | Heterocyclisch substituierte Aryl-Verbindungen und ihre Verwendung |
| DE102009041241A1 (de) | 2009-09-11 | 2011-08-04 | Bayer Schering Pharma Aktiengesellschaft, 13353 | Substituierte Aryl-Verbindungen und ihre Verwendung |
| DE102009041242A1 (de) | 2009-09-11 | 2011-12-15 | Bayer Schering Pharma Aktiengesellschaft | Heterocyclisch substituierte Aryl-Verbindungen und ihre Verwendung |
| US8383654B2 (en) | 2008-11-17 | 2013-02-26 | Panmira Pharmaceuticals, Llc | Heterocyclic antagonists of prostaglandin D2 receptors |
| WO2012003405A1 (en) | 2010-06-30 | 2012-01-05 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| NZ609955A (en) | 2010-11-09 | 2015-05-29 | Ironwood Pharmaceuticals Inc | Sgc stimulators |
| EP2797915B1 (en) | 2011-12-27 | 2016-07-13 | Ironwood Pharmaceuticals, Inc. | 2-benzyl-3-(oxazole/thiazole)-5-(pyrimidin-2-yl)-1(H)-pyrazole derivatives as stimulators of the soluble guanylate cyclase (sGC) for the treatment of e.g. hypertension or heart failure |
| WO2014000178A1 (en) | 2012-06-27 | 2014-01-03 | Merck Sharp & Dohme Corp. | Sulfonamide derivatives and methods of use thereof for improving the pharmacokinetics of a drug |
| CN104540813A (zh) * | 2012-06-27 | 2015-04-22 | 默沙东公司 | 磺酰胺衍生物以及使用它们用于改善药物的药物动力学的方法 |
| WO2014194519A1 (en) | 2013-06-07 | 2014-12-11 | Merck Sharp & Dohme Corp. | Imidazole derivatives and methods of use thereof for improving pharmacokinetics of drug |
| WO2015070367A1 (en) | 2013-11-12 | 2015-05-21 | Merck Sharp & Dohme Corp. | Piperidine or piperazine linked imidazole and triazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug |
| WO2015070366A1 (en) * | 2013-11-12 | 2015-05-21 | Merck Sharp & Dohme Corp. | Aryl linked imidazole and triazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug |
| US20220144797A1 (en) * | 2019-02-08 | 2022-05-12 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | 20-hete formation inhibitors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0024795D0 (en) | 2000-10-10 | 2000-11-22 | Hoffmann La Roche | Pyrazole derivatives for the treatment of viral diseases |
| EP1373263B1 (en) * | 2001-04-05 | 2004-10-27 | Torrent Pharmaceuticals Ltd | Heterocyclic compounds for aging-related and diabetic vascular complications |
| US7008953B2 (en) * | 2003-07-30 | 2006-03-07 | Agouron Pharmaceuticals, Inc. | 3, 5 Disubstituted indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation |
| US7662844B2 (en) * | 2004-07-12 | 2010-02-16 | Osi Pharmaceuticals, Inc. | Naphthylene derivatives as cytochrome P450 inhibitors |
| EA014329B1 (ru) | 2005-09-23 | 2010-10-29 | Пфайзер Продактс Инк. | Пиридинаминосульфонилзамещенные бензамиды в качестве ингибиторов цитохрома р450 3а4 (cyp3a4) |
-
2007
- 2007-06-25 NZ NZ574207A patent/NZ574207A/en not_active IP Right Cessation
- 2007-06-25 WO PCT/IB2007/001878 patent/WO2008004096A1/en active Application Filing
- 2007-06-25 RS RSP-2009/0036A patent/RS20090036A/sr unknown
- 2007-06-25 AU AU2007270814A patent/AU2007270814B2/en not_active Ceased
- 2007-06-25 MX MX2009000482A patent/MX2009000482A/es not_active Application Discontinuation
- 2007-06-25 CA CA002660031A patent/CA2660031A1/en not_active Abandoned
- 2007-06-25 CN CNA200780032889XA patent/CN101511812A/zh active Pending
- 2007-06-25 AP AP2009004763A patent/AP2009004763A0/xx unknown
- 2007-06-25 EA EA200900135A patent/EA200900135A1/ru unknown
- 2007-06-25 KR KR1020097002315A patent/KR20090034958A/ko not_active Application Discontinuation
- 2007-06-25 EP EP07734950A patent/EP2046774A1/en not_active Withdrawn
- 2007-06-28 US US11/770,698 patent/US7919488B2/en not_active Expired - Fee Related
- 2007-07-03 AR ARP070102977A patent/AR062154A1/es not_active Application Discontinuation
- 2007-07-04 TW TW096124262A patent/TWI334867B/zh not_active IP Right Cessation
- 2007-07-04 UY UY30460A patent/UY30460A1/es unknown
- 2007-07-04 GT GT200700053A patent/GT200700053A/es unknown
- 2007-07-04 PE PE2007000860A patent/PE20080998A1/es not_active Application Discontinuation
-
2009
- 2009-01-13 IL IL196490A patent/IL196490A0/en unknown
- 2009-01-20 CR CR10573A patent/CR10573A/es unknown
- 2009-01-21 ZA ZA200900478A patent/ZA200900478B/xx unknown
- 2009-01-22 NO NO20090346A patent/NO20090346L/no not_active Application Discontinuation
- 2009-01-30 TN TN2009000033A patent/TN2009000033A1/fr unknown
- 2009-02-04 CO CO09010549A patent/CO6150178A2/es unknown
- 2009-02-05 MA MA31618A patent/MA30629B1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CO6150178A2 (es) | 2010-04-20 |
| NO20090346L (no) | 2009-02-19 |
| TW200811159A (en) | 2008-03-01 |
| CN101511812A (zh) | 2009-08-19 |
| UY30460A1 (es) | 2008-02-29 |
| US20080021011A1 (en) | 2008-01-24 |
| MA30629B1 (fr) | 2009-08-03 |
| EA200900135A1 (ru) | 2009-06-30 |
| CR10573A (es) | 2009-02-12 |
| US7919488B2 (en) | 2011-04-05 |
| RS20090036A (en) | 2010-06-30 |
| NZ574207A (en) | 2010-10-29 |
| KR20090034958A (ko) | 2009-04-08 |
| PE20080998A1 (es) | 2008-08-15 |
| AR062154A1 (es) | 2008-10-22 |
| TN2009000033A1 (fr) | 2010-08-19 |
| AU2007270814A1 (en) | 2008-01-10 |
| GT200700053A (es) | 2009-08-03 |
| TWI334867B (en) | 2010-12-21 |
| MX2009000482A (es) | 2009-01-27 |
| AP2009004763A0 (en) | 2009-02-28 |
| AU2007270814B2 (en) | 2011-07-14 |
| IL196490A0 (en) | 2011-07-31 |
| EP2046774A1 (en) | 2009-04-15 |
| CA2660031A1 (en) | 2008-01-10 |
| WO2008004096A1 (en) | 2008-01-10 |
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