GT200100243A - Activadores heteroaromaticos fusionados de la glucoquinasa - Google Patents

Activadores heteroaromaticos fusionados de la glucoquinasa

Info

Publication number
GT200100243A
GT200100243A GT200100243A GT200100243A GT200100243A GT 200100243 A GT200100243 A GT 200100243A GT 200100243 A GT200100243 A GT 200100243A GT 200100243 A GT200100243 A GT 200100243A GT 200100243 A GT200100243 A GT 200100243A
Authority
GT
Guatemala
Prior art keywords
glucoquinasa
fusioned
heteroaromatic
activators
compounds
Prior art date
Application number
GT200100243A
Other languages
English (en)
Inventor
Wendy Lea Corbett
Joseph Samuel Grimsby
Nancy-Ellen Haynes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT200100243A publication Critical patent/GT200100243A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Quinoline Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

LA SIGUIENTE INVENCION SE REFIERE A LOS COMPUESTOS ACTIVADORES DE LA GLUCOQUINASA DE FORMULA(I) EN DONDE R1, R2, R3, R4, R5, R6, M, Q, W,Y,Z , SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. LOS COMPUESTOS DE LA PRESENTE INVENCION SIRVEN PARA TRATAMIENTO O PREVENCION DE LA DIABETES TIPO II.
GT200100243A 2000-12-06 2001-12-05 Activadores heteroaromaticos fusionados de la glucoquinasa GT200100243A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25163700P 2000-12-06 2000-12-06

Publications (1)

Publication Number Publication Date
GT200100243A true GT200100243A (es) 2002-06-04

Family

ID=22952803

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200100243A GT200100243A (es) 2000-12-06 2001-12-05 Activadores heteroaromaticos fusionados de la glucoquinasa

Country Status (21)

Country Link
US (3) US6448399B1 (es)
EP (1) EP1341774B1 (es)
JP (1) JP4109111B2 (es)
KR (1) KR100545431B1 (es)
CN (1) CN1226294C (es)
AR (1) AR031627A1 (es)
AT (1) ATE316965T1 (es)
AU (2) AU2002221902B2 (es)
BR (1) BR0115999A (es)
CA (1) CA2429642C (es)
DE (1) DE60117059T2 (es)
DK (1) DK1341774T3 (es)
ES (1) ES2256340T3 (es)
GT (1) GT200100243A (es)
MX (1) MXPA03005119A (es)
PA (1) PA8534301A1 (es)
PE (1) PE20020753A1 (es)
PT (1) PT1341774E (es)
UY (1) UY27055A1 (es)
WO (1) WO2002046173A1 (es)
ZA (1) ZA200303748B (es)

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Also Published As

Publication number Publication date
CN1476438A (zh) 2004-02-18
JP2004517087A (ja) 2004-06-10
JP4109111B2 (ja) 2008-07-02
AR031627A1 (es) 2003-09-24
KR100545431B1 (ko) 2006-01-24
AU2002221902B2 (en) 2006-11-23
CN1226294C (zh) 2005-11-09
US6448399B1 (en) 2002-09-10
US6545155B2 (en) 2003-04-08
US20020107396A1 (en) 2002-08-08
CA2429642A1 (en) 2002-06-13
US6441184B1 (en) 2002-08-27
PE20020753A1 (es) 2002-08-27
US20020103241A1 (en) 2002-08-01
AU2190202A (en) 2002-06-18
US20020103199A1 (en) 2002-08-01
EP1341774B1 (en) 2006-02-01
PT1341774E (pt) 2006-05-31
UY27055A1 (es) 2002-07-31
PA8534301A1 (es) 2002-08-26
MXPA03005119A (es) 2004-10-15
KR20030068555A (ko) 2003-08-21
ATE316965T1 (de) 2006-02-15
DK1341774T3 (da) 2006-06-12
WO2002046173A1 (en) 2002-06-13
DE60117059T2 (de) 2006-10-26
DE60117059D1 (de) 2006-04-13
ES2256340T3 (es) 2006-07-16
EP1341774A1 (en) 2003-09-10
ZA200303748B (en) 2004-08-16
CA2429642C (en) 2007-11-20
BR0115999A (pt) 2003-09-30

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