GR970300027T1 - Process for the preparation of a dicarboxylic acid dichloride - Google Patents
Process for the preparation of a dicarboxylic acid dichlorideInfo
- Publication number
- GR970300027T1 GR970300027T1 GR970300027T GR970300027T GR970300027T1 GR 970300027 T1 GR970300027 T1 GR 970300027T1 GR 970300027 T GR970300027 T GR 970300027T GR 970300027 T GR970300027 T GR 970300027T GR 970300027 T1 GR970300027 T1 GR 970300027T1
- Authority
- GR
- Greece
- Prior art keywords
- preparation
- acid dichloride
- dicarboxylic acid
- triiodo
- amino
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 title 1
- DKPFZGUDAPQIHT-UHFFFAOYSA-N butyl acetate Chemical compound CCCCOC(C)=O DKPFZGUDAPQIHT-UHFFFAOYSA-N 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- UOCLXMDMGBRAIB-UHFFFAOYSA-N 1,1,1-trichloroethane Chemical compound CC(Cl)(Cl)Cl UOCLXMDMGBRAIB-UHFFFAOYSA-N 0.000 abstract 1
- FBJVWRITWDYUAC-UHFFFAOYSA-N 5-amino-2,4,6-triiodobenzene-1,3-dicarbonyl chloride Chemical compound NC1=C(I)C(C(Cl)=O)=C(I)C(C(Cl)=O)=C1I FBJVWRITWDYUAC-UHFFFAOYSA-N 0.000 abstract 1
- JEZJSNULLBSYHV-UHFFFAOYSA-N 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid Chemical compound NC1=C(I)C(C(O)=O)=C(I)C(C(O)=O)=C1I JEZJSNULLBSYHV-UHFFFAOYSA-N 0.000 abstract 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- SBZXBUIDTXKZTM-UHFFFAOYSA-N diglyme Chemical compound COCCOCCOC SBZXBUIDTXKZTM-UHFFFAOYSA-N 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002430 hydrocarbons Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 150000003512 tertiary amines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
- C07C381/10—Compounds containing sulfur atoms doubly-bound to nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI951044A IT1274546B (it) | 1995-05-23 | 1995-05-23 | Processo per la preparazione del dicloruro dell'acido 5-ammino-2,4,- 6-triiodoisoftalico |
| ITRM950550 IT1281320B1 (it) | 1995-08-04 | 1995-08-04 | Procedimento di preparazione di dicloruro dell'acido 5-ammino-2,4,6- triiodo-1,3-benzendicarbossilico per reazione dell'acido |
| PCT/EP1996/002103 WO1996037459A1 (en) | 1995-05-23 | 1996-05-17 | Process for the preparation of a dicarboxylic acid dichloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR970300027T1 true GR970300027T1 (en) | 1997-09-30 |
Family
ID=26331277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR970300027T GR970300027T1 (en) | 1995-05-23 | 1997-09-30 | Process for the preparation of a dicarboxylic acid dichloride |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5616795A (ja) |
| EP (1) | EP0773924B1 (ja) |
| JP (1) | JP4012566B2 (ja) |
| KR (1) | KR100255914B1 (ja) |
| CN (1) | CN1157367C (ja) |
| AT (1) | ATE176663T1 (ja) |
| AU (1) | AU702895B2 (ja) |
| BR (1) | BR9606488A (ja) |
| CA (1) | CA2195636C (ja) |
| CZ (1) | CZ290345B6 (ja) |
| DE (2) | DE69601525T2 (ja) |
| DK (1) | DK0773924T3 (ja) |
| ES (1) | ES2103252T3 (ja) |
| GR (1) | GR970300027T1 (ja) |
| HU (1) | HU216548B (ja) |
| IL (1) | IL118359A (ja) |
| MX (1) | MX9700548A (ja) |
| NO (1) | NO313696B1 (ja) |
| PL (1) | PL182447B1 (ja) |
| SI (1) | SI9620012A (ja) |
| SK (1) | SK8797A3 (ja) |
| WO (1) | WO1996037459A1 (ja) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1271107B (it) * | 1994-11-29 | 1997-05-26 | Zambon Spa | Processo per la preparazione di un intermedio utile nella sintesi di composti organici |
| IT1292037B1 (it) * | 1997-05-30 | 1999-01-25 | Bracco Spa | Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen- |
| WO2007073202A1 (en) | 2005-12-19 | 2007-06-28 | Ge Healthcare As | Purification process of iodixanol |
| GB0717189D0 (en) * | 2007-09-04 | 2007-10-17 | Syngenta Participations Ag | Novel processes and compounds |
| JP2011509943A (ja) | 2008-01-14 | 2011-03-31 | マリンクロッド・インコーポレイテッド | イオシメノールを調製するためのプロセス |
| EP2230227A1 (en) | 2009-03-20 | 2010-09-22 | Bracco Imaging S.p.A | Process for the preparation of triiodinated carboxylic aromatic derivatives |
| EP2243767A1 (en) * | 2009-04-21 | 2010-10-27 | Bracco Imaging S.p.A | Process for the iodination of aromatic compounds |
| US7999134B2 (en) | 2009-07-21 | 2011-08-16 | Ge Healthcare As | Crystallization of iodixanol using milling |
| US7999135B2 (en) | 2009-07-21 | 2011-08-16 | Ge Healthcare As | Crystallization of iodixanol using ultrasound |
| EP2504298B1 (en) | 2009-11-26 | 2016-09-21 | iMAX Diagnostic Imaging Holding Limited | Preparation and purification of iodixanol |
| EP2394984A1 (en) | 2010-06-10 | 2011-12-14 | Bracco Imaging S.p.A | Process for the iodination of phenolic derivatives |
| ES2699246T3 (es) | 2012-12-11 | 2019-02-08 | Bracco Imaging Spa | Proceso continuo para la preparación de ácido (S)-2-acetiloxipropionico |
| CA2927706C (en) | 2013-11-05 | 2018-05-29 | Bracco Imaging Spa | Process for the preparation of iopamidol |
| CA2949433C (en) | 2014-06-10 | 2022-05-03 | Bracco Imaging Spa | Method for the preparation of (s)-2-acetyloxypropionic acid and derivatives thereof |
| CN104230731B (zh) * | 2014-09-24 | 2016-01-20 | 武汉理工大学 | 造影剂中间体三碘异酞酰氯的制备方法 |
| WO2018104228A1 (en) | 2016-12-05 | 2018-06-14 | Bracco Imaging Spa | Mechanochemical synthesis of radiographic agents intermediates |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH608189A5 (ja) * | 1974-12-13 | 1978-12-29 | Savac Ag | |
| IT1193211B (it) * | 1979-08-09 | 1988-06-15 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono |
| IT1207226B (it) * | 1979-08-09 | 1989-05-17 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono. |
| US4396598A (en) * | 1982-01-11 | 1983-08-02 | Mallinckrodt, Inc. | Triiodoisophthalamide X-ray contrast agent |
| FR2541676A1 (fr) * | 1983-02-25 | 1984-08-31 | Guerbet Sa | Composes non-ioniques a structures benzenique iodee ou bromee et produits opacifiants en contenant |
| US5075502A (en) * | 1989-12-13 | 1991-12-24 | Mallinckrodt, Inc. | Nonionic x-ray contrast agents, compositions and methods |
| US5191120A (en) * | 1989-12-13 | 1993-03-02 | Mallinckrodt Medical, Inc. | Process for preparing nonionic X-ray contrast agents |
| IT1271107B (it) * | 1994-11-29 | 1997-05-26 | Zambon Spa | Processo per la preparazione di un intermedio utile nella sintesi di composti organici |
-
1996
- 1996-05-17 ES ES96916098T patent/ES2103252T3/es not_active Expired - Lifetime
- 1996-05-17 CN CNB961905271A patent/CN1157367C/zh not_active Expired - Lifetime
- 1996-05-17 DK DK96916098T patent/DK0773924T3/da active
- 1996-05-17 KR KR1019970700402A patent/KR100255914B1/ko not_active IP Right Cessation
- 1996-05-17 PL PL96318311A patent/PL182447B1/pl unknown
- 1996-05-17 BR BR9606488A patent/BR9606488A/pt not_active Application Discontinuation
- 1996-05-17 SK SK87-97A patent/SK8797A3/sk unknown
- 1996-05-17 AT AT96916098T patent/ATE176663T1/de active
- 1996-05-17 US US08/650,094 patent/US5616795A/en not_active Expired - Lifetime
- 1996-05-17 EP EP96916098A patent/EP0773924B1/en not_active Expired - Lifetime
- 1996-05-17 DE DE69601525T patent/DE69601525T2/de not_active Expired - Lifetime
- 1996-05-17 MX MX9700548A patent/MX9700548A/es unknown
- 1996-05-17 CA CA002195636A patent/CA2195636C/en not_active Expired - Lifetime
- 1996-05-17 SI SI9620012A patent/SI9620012A/sl unknown
- 1996-05-17 AU AU58978/96A patent/AU702895B2/en not_active Expired
- 1996-05-17 CZ CZ1997187A patent/CZ290345B6/cs not_active IP Right Cessation
- 1996-05-17 DE DE0773924T patent/DE773924T1/de active Pending
- 1996-05-17 WO PCT/EP1996/002103 patent/WO1996037459A1/en active IP Right Grant
- 1996-05-17 HU HU9700188A patent/HU216548B/hu unknown
- 1996-05-17 JP JP53534596A patent/JP4012566B2/ja not_active Expired - Lifetime
- 1996-05-22 IL IL11835996A patent/IL118359A/xx not_active IP Right Cessation
-
1997
- 1997-01-21 NO NO19970261A patent/NO313696B1/no not_active IP Right Cessation
- 1997-09-30 GR GR970300027T patent/GR970300027T1/el unknown
Also Published As
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