GR930100426A - Παράγωγα βενζ(-e)ινδενίου. - Google Patents
Παράγωγα βενζ(-e)ινδενίου.Info
- Publication number
- GR930100426A GR930100426A GR930100426A GR930100426A GR930100426A GR 930100426 A GR930100426 A GR 930100426A GR 930100426 A GR930100426 A GR 930100426A GR 930100426 A GR930100426 A GR 930100426A GR 930100426 A GR930100426 A GR 930100426A
- Authority
- GR
- Greece
- Prior art keywords
- derivatives
- group
- alkyl
- benzene
- nitrogen atom
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/32—Oximes
- C07C251/50—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals
- C07C251/58—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/60—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups having oxygen atoms of carbamate groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
Abstract
Η εφεύρεση αφορά νέα, φαρμακευτικώς δραστικά βενζ(ε)ινδενοπαράγωγα μία μέ?οδο δια την παρασκευή αυτών, φαρμακευτικές συν?έσεις που περιεχουν αυτά, περαιτέρω την χρησιμοποίηση των αναφερ?έντων παραγώγων βενζ(ε)ινδενίου εις την αγωγή ορισμένων ασ?ενειών και κατά την παρασκευή φαρμακευτικών συν?έσεων καταλλήλων δια την αγωγή των αναφερ?έντων ασ?ενειών.Τα νέα παράγωγα βενζ(ε)ινδενίου συμφωνως προς την εφεύρεση αντιστοιχούν εις τον γενικό τύπο. Χ Η Μ Ι Κ Ο Σ Τ Υ Π Ο Σ εις τον οποίο το Α παριστά μια ομάδα του τύπου Alk-NR1R2, όπου το alk παριστά μια C2-7 αλκυλενομάδα ενδεχομένως φέρουσα έναν υδροξυ υποκαταστάτη, τα R1 και R2 είναι ανεξαρτήτως υδρογόνου, C1-7-αλκυλ, C2-7-αλκυνυλ, C2-7-αλκυνυλ ή C3-7-κυκλοαλκυλ ή τα R1 και R2 μαζί με το άτομο αζώτου εις το οποίο είναι συνδεδεμένα σχηματίζουν εναν 4 έως 7 μελή δακτυλιο, ενδεχομένως περιέχοντα ένα άτομο οξυγόνου ή ένα περαιτέρω άτομο αζώτου, το οποίο τελευταίο μπορεί να φέρει ένα φαινυλ, βενζυλ, πυριδυλ, πυριμιδινυλ ή C 1-3 αλκυλυπόλοκαταστάτη, οι οποίοι υποκατάστάτες δύνανται πάλιν να φέρουν μια υδροξυ ή με?οξυομάδα ή ένα άτομο αλογόνου ήR1 και R2 μαζί με το άτομο αζώτου εις το οποίο αυτά είναι συνδεδεμένα σχηματίζουν μια φ?αλιμιδοομάδα ή το Α παριστά πυριμιδινο, 2,3-εποξυπροπυλ ή μια ομάδα του τύπου -C(O)NHR,όπου το R3 παριστά C1-7 αλκυλ, C2-7 αλκενυλ ή C3-8 κυκλοαλκυλ και το R σημαίνει υδρογόνο ή C1-7 αλκυλ,στερεοισομερή και οπτικώς δραστικά ισομερή και τα πι?ανά μίγματα αυτών, περαιτέρω άλατα δια προσ?ήκης οξέος και τεταρτοταγή παραγωγα αμμωνίου των ενώσεων αυτών.ω
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU9203406A HU212262B (en) | 1992-10-30 | 1992-10-30 | Process to prepare benz /e/ indene derivs. and the pharmaceutical compns. contg. them |
Publications (1)
Publication Number | Publication Date |
---|---|
GR930100426A true GR930100426A (el) | 1994-06-30 |
Family
ID=10982489
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR930100426A GR930100426A (el) | 1992-10-30 | 1993-10-29 | Παράγωγα βενζ(-e)ινδενίου. |
Country Status (17)
Country | Link |
---|---|
US (1) | US5439940A (el) |
EP (1) | EP0595364B1 (el) |
JP (1) | JPH0770033A (el) |
CN (1) | CN1089939A (el) |
AT (1) | AT403580B (el) |
CA (1) | CA2102042A1 (el) |
CZ (1) | CZ230893A3 (el) |
DE (1) | DE69303798T2 (el) |
DK (1) | DK0595364T3 (el) |
ES (1) | ES2099658B1 (el) |
FI (1) | FI934823A (el) |
FR (1) | FR2697520B1 (el) |
GR (1) | GR930100426A (el) |
HU (2) | HU212262B (el) |
IT (1) | IT1272762B (el) |
YU (1) | YU68693A (el) |
ZA (1) | ZA938087B (el) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5312743B2 (ja) * | 2006-02-01 | 2013-10-09 | 富士フイルム株式会社 | オキシム化合物及びそれを含む感光性組成物 |
KR20090104877A (ko) * | 2007-01-23 | 2009-10-06 | 후지필름 가부시키가이샤 | 옥심 화합물, 감광성 조성물, 컬러 필터, 그 제조방법 및 액정표시소자 |
JP2008249857A (ja) * | 2007-03-29 | 2008-10-16 | Fujifilm Corp | 感光性樹脂組成物、カラーフィルタ及びその製造方法、並びに液晶表示素子 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL6503019A (el) * | 1965-03-10 | 1966-09-12 | ||
SE371193B (el) * | 1972-03-24 | 1974-11-11 | Kabi Ab | |
GB1474316A (en) * | 1975-02-12 | 1977-05-25 | Seperic | O-aminoalkyl oximes |
HU178518B (en) * | 1978-12-19 | 1982-05-28 | Egyt Gyogyszervegyeszeti Gyar | Process for preparing cyclododekanone oxime ethers |
AU532700B2 (en) * | 1979-04-02 | 1983-10-13 | Sumitomo Chemical Company, Limited | Diphenylalkanoether |
HU212415B (en) * | 1989-08-25 | 1996-06-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing new cyclic oxym derivatives and pharmaceutical compositions containing them as active components |
-
1992
- 1992-10-30 HU HU9203406A patent/HU212262B/hu not_active IP Right Cessation
-
1993
- 1993-10-26 ES ES09302234A patent/ES2099658B1/es not_active Expired - Fee Related
- 1993-10-28 US US08/141,954 patent/US5439940A/en not_active Expired - Fee Related
- 1993-10-29 CZ CZ932308A patent/CZ230893A3/cs unknown
- 1993-10-29 CA CA002102042A patent/CA2102042A1/en not_active Abandoned
- 1993-10-29 GR GR930100426A patent/GR930100426A/el unknown
- 1993-10-29 FI FI934823A patent/FI934823A/fi not_active Application Discontinuation
- 1993-10-29 FR FR9312928A patent/FR2697520B1/fr not_active Expired - Fee Related
- 1993-10-29 CN CN93119801A patent/CN1089939A/zh active Pending
- 1993-10-29 ZA ZA938087A patent/ZA938087B/xx unknown
- 1993-10-29 YU YU68693A patent/YU68693A/sh unknown
- 1993-10-29 AT AT0218893A patent/AT403580B/de not_active IP Right Cessation
- 1993-10-29 IT ITMI932303A patent/IT1272762B/it active IP Right Grant
- 1993-11-01 JP JP5273903A patent/JPH0770033A/ja active Pending
- 1993-11-02 DE DE69303798T patent/DE69303798T2/de not_active Expired - Fee Related
- 1993-11-02 DK DK93117721.6T patent/DK0595364T3/da active
- 1993-11-02 EP EP93117721A patent/EP0595364B1/en not_active Expired - Lifetime
-
1995
- 1995-06-20 HU HU95P/P00263P patent/HU211494A9/hu unknown
Also Published As
Publication number | Publication date |
---|---|
EP0595364A1 (en) | 1994-05-04 |
FR2697520B1 (fr) | 1995-03-24 |
ATA218893A (de) | 1997-08-15 |
DE69303798T2 (de) | 1996-11-28 |
CZ230893A3 (en) | 1994-06-15 |
FI934823A (fi) | 1994-05-01 |
AT403580B (de) | 1998-03-25 |
ES2099658A1 (es) | 1997-05-16 |
HU212262B (en) | 1996-04-29 |
ES2099658B1 (es) | 1998-02-01 |
ITMI932303A1 (it) | 1995-04-29 |
ITMI932303A0 (it) | 1993-10-29 |
FI934823A0 (fi) | 1993-10-29 |
EP0595364B1 (en) | 1996-07-24 |
US5439940A (en) | 1995-08-08 |
HU211494A9 (en) | 1995-11-28 |
HU9203406D0 (en) | 1993-01-28 |
DK0595364T3 (da) | 1996-08-26 |
IT1272762B (it) | 1997-06-26 |
DE69303798D1 (de) | 1996-08-29 |
JPH0770033A (ja) | 1995-03-14 |
CN1089939A (zh) | 1994-07-27 |
HUT68238A (en) | 1995-06-28 |
FR2697520A1 (fr) | 1994-05-06 |
ZA938087B (en) | 1994-06-07 |
CA2102042A1 (en) | 1994-05-01 |
YU68693A (sh) | 1997-07-31 |
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