ATA218893A - Neue benz(e)inden-derivate, verfahren zu ihrer herstellung und die diese verbindungen enthaltenden arzneimittelpräparate - Google Patents

Neue benz(e)inden-derivate, verfahren zu ihrer herstellung und die diese verbindungen enthaltenden arzneimittelpräparate

Info

Publication number
ATA218893A
ATA218893A AT0218893A AT218893A ATA218893A AT A218893 A ATA218893 A AT A218893A AT 0218893 A AT0218893 A AT 0218893A AT 218893 A AT218893 A AT 218893A AT A218893 A ATA218893 A AT A218893A
Authority
AT
Austria
Prior art keywords
compounds
production
products containing
medicinal products
indene derivatives
Prior art date
Application number
AT0218893A
Other languages
English (en)
Other versions
AT403580B (de
Inventor
Klara Reiter
Zoltan Dr Budai
Tibor Dr Mezei
Gabor Dr Blasko
Gyula Dr Simig
Istvan Dr Gyertyan
Lujza Dr Petoecz
Marton Dr Fekete
Katalin Dr Szemeredi
Istvan Gacsalyi
Gabor Gigler
Ludmilla Rohacs
Maria Szecsey
Enikoe Szirt
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of ATA218893A publication Critical patent/ATA218893A/de
Application granted granted Critical
Publication of AT403580B publication Critical patent/AT403580B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/50—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals
    • C07C251/58—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/60—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups having oxygen atoms of carbamate groups bound to nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Indole Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT0218893A 1992-10-30 1993-10-29 Neue benz(e)inden-derivate, verfahren zu ihrer herstellung und die diese verbindungen enthaltenden arzneimittelpräparate AT403580B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9203406A HU212262B (en) 1992-10-30 1992-10-30 Process to prepare benz /e/ indene derivs. and the pharmaceutical compns. contg. them

Publications (2)

Publication Number Publication Date
ATA218893A true ATA218893A (de) 1997-08-15
AT403580B AT403580B (de) 1998-03-25

Family

ID=10982489

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0218893A AT403580B (de) 1992-10-30 1993-10-29 Neue benz(e)inden-derivate, verfahren zu ihrer herstellung und die diese verbindungen enthaltenden arzneimittelpräparate

Country Status (17)

Country Link
US (1) US5439940A (de)
EP (1) EP0595364B1 (de)
JP (1) JPH0770033A (de)
CN (1) CN1089939A (de)
AT (1) AT403580B (de)
CA (1) CA2102042A1 (de)
CZ (1) CZ230893A3 (de)
DE (1) DE69303798T2 (de)
DK (1) DK0595364T3 (de)
ES (1) ES2099658B1 (de)
FI (1) FI934823A7 (de)
FR (1) FR2697520B1 (de)
GR (1) GR930100426A (de)
HU (2) HU212262B (de)
IT (1) IT1272762B (de)
YU (1) YU68693A (de)
ZA (1) ZA938087B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5312743B2 (ja) * 2006-02-01 2013-10-09 富士フイルム株式会社 オキシム化合物及びそれを含む感光性組成物
KR20090104877A (ko) * 2007-01-23 2009-10-06 후지필름 가부시키가이샤 옥심 화합물, 감광성 조성물, 컬러 필터, 그 제조방법 및 액정표시소자
JP2008249857A (ja) * 2007-03-29 2008-10-16 Fujifilm Corp 感光性樹脂組成物、カラーフィルタ及びその製造方法、並びに液晶表示素子

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6503019A (de) * 1965-03-10 1966-09-12
SE371193B (de) * 1972-03-24 1974-11-11 Kabi Ab
GB1474316A (en) * 1975-02-12 1977-05-25 Seperic O-aminoalkyl oximes
HU178518B (en) * 1978-12-19 1982-05-28 Egyt Gyogyszervegyeszeti Gyar Process for preparing cyclododekanone oxime ethers
AU532700B2 (en) * 1979-04-02 1983-10-13 Sumitomo Chemical Company, Limited Diphenylalkanoether
HU212415B (en) * 1989-08-25 1996-06-28 Egyt Gyogyszervegyeszeti Gyar Process for producing new cyclic oxym derivatives and pharmaceutical compositions containing them as active components

Also Published As

Publication number Publication date
HU9203406D0 (en) 1993-01-28
HU211494A9 (en) 1995-11-28
FI934823A7 (fi) 1994-05-01
CA2102042A1 (en) 1994-05-01
HU212262B (en) 1996-04-29
FR2697520B1 (fr) 1995-03-24
FR2697520A1 (fr) 1994-05-06
ES2099658A1 (es) 1997-05-16
JPH0770033A (ja) 1995-03-14
DE69303798T2 (de) 1996-11-28
EP0595364A1 (de) 1994-05-04
IT1272762B (it) 1997-06-26
CN1089939A (zh) 1994-07-27
DE69303798D1 (de) 1996-08-29
FI934823A0 (fi) 1993-10-29
HUT68238A (en) 1995-06-28
YU68693A (sh) 1997-07-31
ITMI932303A1 (it) 1995-04-29
US5439940A (en) 1995-08-08
ITMI932303A0 (it) 1993-10-29
AT403580B (de) 1998-03-25
ZA938087B (en) 1994-06-07
EP0595364B1 (de) 1996-07-24
ES2099658B1 (es) 1998-02-01
DK0595364T3 (da) 1996-08-26
CZ230893A3 (en) 1994-06-15
GR930100426A (el) 1994-06-30

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties