GR880100650A - Μεθοδος παρασκευης νεων συμπυκνωμενων παραγωγων κινολινιου & ισοκινολινιου - Google Patents
Μεθοδος παρασκευης νεων συμπυκνωμενων παραγωγων κινολινιου & ισοκινολινιουInfo
- Publication number
- GR880100650A GR880100650A GR880100650A GR880100650A GR880100650A GR 880100650 A GR880100650 A GR 880100650A GR 880100650 A GR880100650 A GR 880100650A GR 880100650 A GR880100650 A GR 880100650A GR 880100650 A GR880100650 A GR 880100650A
- Authority
- GR
- Greece
- Prior art keywords
- alkyl
- hydrogen
- present
- phenyl
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/08—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Αι νέαι ενώσεις του γενικου τύπου Ι, εις τον οποίον το R1 παριστά C1-4 αλκυλ ή αραλκυλ ή υδρογόνου και το R2 παριστά υδροξυ ή τα R1 και R2 μαζί σχηματίζουν έναν δεσμόν σθένους το R3 είναι υδρογόνον, C1-4 αλκυλ, C1-4 αλκοξυ, φαινυλ, αμινο, αλκυλοθειο ή μία ομάς του τύπου -NR7R8 εις τον οποίον τα R7 και R8 ημπορεί να είναι όμοια ή διαφορετικά και παριστούν υδρογόνον, C1-4 αλκυλ, φαινυλ-C, αλκυλ, υδροξυ-C αλκυλ ή δι-(C1-4 αλκυλ)-αμινο-C1-4 αλκυλ λη μαζί με τον άτομον αζώτου επί του οποίου είναι συνδεδεμένα σχηματίζουν έναν εμαμελή ετεροκυκλικόν δακτύλιον ο οποίος ημπορεί ενδεχομένως να περιέχη ένα επιπλέον άτομο αζώτου, οξυγόνου ή θείου ή τα R2 και R3 μαζί σχηματίζουν μίαν οξο (=0) ή θειοξο(=S) ομάδαν το R4 παριστά υδρογόνον C1-4 αλκυλ ή φαινυλ το οποίον ημπορεί ενδεχομένως να φέρη έναν ή δύο υποκαταστάτην (-ας) αλογόνου ή νιτρο, το Ζ είναι μια ομάς του τύπου (α) ή (β) και το Α- παριστά έναν ανιόν), και ισομερή αυτών έχουν χρησίμους τοπικές και αναισθητικές,αντικαταθληπτικές, ηρεμιστικο-κατευναστικές και χαλαρωτικες του λείου μυός ιδιότητες αι οποίαι συνοδεύονται από ένα ασθενέστερον αναλγητικόν αποτέλεσμα και είναι χρήσιμαι εις την θεραπευτικήν.ω
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU874436A HU203099B (en) | 1987-10-02 | 1987-10-02 | Process for producing condensed quinolinium- and isoquinolinium derivatives and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR880100650A true GR880100650A (el) | 1989-09-29 |
Family
ID=10967954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR880100650A GR880100650A (el) | 1987-10-02 | 1988-09-30 | Μεθοδος παρασκευης νεων συμπυκνωμενων παραγωγων κινολινιου & ισοκινολινιου |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4994448A (el) |
| JP (1) | JPH01163178A (el) |
| KR (1) | KR890006601A (el) |
| AU (1) | AU608066B2 (el) |
| BE (1) | BE1002518A4 (el) |
| CH (1) | CH676847A5 (el) |
| DD (1) | DD273632A5 (el) |
| DE (1) | DE3833615A1 (el) |
| DK (1) | DK549588A (el) |
| ES (1) | ES2012567A6 (el) |
| FI (1) | FI884535A (el) |
| FR (1) | FR2621314B1 (el) |
| GB (1) | GB2210369B (el) |
| GR (1) | GR880100650A (el) |
| HU (1) | HU203099B (el) |
| IL (1) | IL87875A0 (el) |
| IT (1) | IT8822146A0 (el) |
| NL (1) | NL8802405A (el) |
| PL (1) | PL274989A1 (el) |
| SE (1) | SE8803484L (el) |
| YU (3) | YU182288A (el) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4753499B2 (ja) * | 2001-07-31 | 2011-08-24 | ホリゾン・インターナショナル株式会社 | コイル綴じ製本用表紙及びその表紙付コイル綴じ冊子 |
| CN109438439B (zh) * | 2018-10-08 | 2021-04-13 | 安徽大学 | 四氢异喹啉并1,2,4-三唑类衍生物及其制备方法 |
| EP4247324A1 (en) * | 2020-11-23 | 2023-09-27 | Health Research, Inc. | Compounds and methods to target glucose-stimulated phosphohistidine signaling and esophageal cancer growth |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2552086A1 (fr) * | 1983-09-20 | 1985-03-22 | Egyt Gyogyszervegyeszeti Gyar | Procede pour la preparation de derives condenses d'as-triazine, produits resultants et compositions pharmaceutiques les contenant |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR255086A (el) * | ||||
| HU187305B (en) * | 1980-07-18 | 1985-12-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing condensed as-triazine derivatives |
| HU190504B (en) * | 1983-09-20 | 1986-09-29 | Egis Gyogyszergyar,Hu | Process for preparing condensed as-triazinium-derivatives |
| HU190505B (en) * | 1983-09-20 | 1986-09-29 | Egis Gyogyszergyar,Hu | Process for preparing condensed as-triazine-derivatives of twin ion type |
-
1987
- 1987-10-02 HU HU874436A patent/HU203099B/hu not_active IP Right Cessation
-
1988
- 1988-09-29 IL IL87875A patent/IL87875A0/xx unknown
- 1988-09-29 YU YU01822/88A patent/YU182288A/xx unknown
- 1988-09-29 CH CH3626/88A patent/CH676847A5/de not_active IP Right Cessation
- 1988-09-30 DD DD88320333A patent/DD273632A5/de not_active IP Right Cessation
- 1988-09-30 ES ES8803448A patent/ES2012567A6/es not_active Expired - Lifetime
- 1988-09-30 SE SE8803484A patent/SE8803484L/xx not_active Application Discontinuation
- 1988-09-30 PL PL27498988A patent/PL274989A1/xx unknown
- 1988-09-30 DK DK549588A patent/DK549588A/da not_active Application Discontinuation
- 1988-09-30 GB GB8823011A patent/GB2210369B/en not_active Expired - Lifetime
- 1988-09-30 KR KR1019880012757A patent/KR890006601A/ko not_active Application Discontinuation
- 1988-09-30 IT IT8822146A patent/IT8822146A0/it unknown
- 1988-09-30 FR FR888812801A patent/FR2621314B1/fr not_active Expired - Lifetime
- 1988-09-30 AU AU23345/88A patent/AU608066B2/en not_active Ceased
- 1988-09-30 BE BE8801118A patent/BE1002518A4/fr not_active IP Right Cessation
- 1988-09-30 GR GR880100650A patent/GR880100650A/el unknown
- 1988-09-30 JP JP63244722A patent/JPH01163178A/ja active Pending
- 1988-09-30 FI FI884535A patent/FI884535A/fi not_active Application Discontinuation
- 1988-09-30 NL NL8802405A patent/NL8802405A/nl not_active Application Discontinuation
- 1988-09-30 US US07/251,445 patent/US4994448A/en not_active Expired - Fee Related
- 1988-10-03 DE DE3833615A patent/DE3833615A1/de not_active Withdrawn
-
1989
- 1989-11-13 YU YU02155/89A patent/YU215589A/xx unknown
- 1989-11-13 YU YU02156/89A patent/YU215689A/xx unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2552086A1 (fr) * | 1983-09-20 | 1985-03-22 | Egyt Gyogyszervegyeszeti Gyar | Procede pour la preparation de derives condenses d'as-triazine, produits resultants et compositions pharmaceutiques les contenant |
Non-Patent Citations (1)
| Title |
|---|
| CLAIMS SEARCHED: ALL * |
Also Published As
| Publication number | Publication date |
|---|---|
| IL87875A0 (en) | 1989-03-31 |
| FR2621314A1 (fr) | 1989-04-07 |
| SE8803484L (sv) | 1989-04-03 |
| CH676847A5 (el) | 1991-03-15 |
| IT8822146A0 (it) | 1988-09-30 |
| NL8802405A (nl) | 1989-05-01 |
| YU215589A (en) | 1990-12-31 |
| BE1002518A4 (fr) | 1991-03-12 |
| FR2621314B1 (fr) | 1990-10-26 |
| ES2012567A6 (es) | 1990-04-01 |
| YU215689A (en) | 1991-02-28 |
| HU203099B (en) | 1991-05-28 |
| US4994448A (en) | 1991-02-19 |
| SE8803484D0 (sv) | 1988-09-30 |
| FI884535A0 (fi) | 1988-09-30 |
| GB8823011D0 (en) | 1988-11-09 |
| PL274989A1 (en) | 1989-05-02 |
| DK549588A (da) | 1989-04-03 |
| YU182288A (en) | 1990-04-30 |
| KR890006601A (ko) | 1989-06-14 |
| AU608066B2 (en) | 1991-03-21 |
| GB2210369B (en) | 1991-03-20 |
| DE3833615A1 (de) | 1989-04-13 |
| JPH01163178A (ja) | 1989-06-27 |
| AU2334588A (en) | 1989-04-06 |
| DK549588D0 (da) | 1988-09-30 |
| DD273632A5 (de) | 1989-11-22 |
| GB2210369A (en) | 1989-06-07 |
| HUT48626A (en) | 1989-06-28 |
| FI884535A (fi) | 1989-04-03 |
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