GR3026594T3 - Particle mediated transformation of animal skin tissue cells - Google Patents
Particle mediated transformation of animal skin tissue cellsInfo
- Publication number
- GR3026594T3 GR3026594T3 GR980400787T GR980400787T GR3026594T3 GR 3026594 T3 GR3026594 T3 GR 3026594T3 GR 980400787 T GR980400787 T GR 980400787T GR 980400787 T GR980400787 T GR 980400787T GR 3026594 T3 GR3026594 T3 GR 3026594T3
- Authority
- GR
- Greece
- Prior art keywords
- cells
- microprojectiles
- tissue cells
- skin tissue
- mediated transformation
- Prior art date
Links
- 241001465754 Metazoa Species 0.000 title abstract 3
- 230000001404 mediated effect Effects 0.000 title 1
- 239000002245 particle Substances 0.000 title 1
- 230000009466 transformation Effects 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 230000001105 regulatory effect Effects 0.000 abstract 2
- 241000251539 Vertebrata <Metazoa> Species 0.000 abstract 1
- 210000004207 dermis Anatomy 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 230000006461 physiological response Effects 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000022532 regulation of transcription, DNA-dependent Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
- C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/89—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microinjection
- C12N15/895—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microinjection using biolistic methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Mechanical Engineering (AREA)
- Cell Biology (AREA)
- Sustainable Development (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43784889A | 1989-11-16 | 1989-11-16 | |
PCT/US1990/006597 WO1991007487A1 (en) | 1989-11-16 | 1990-11-13 | Particle-mediated transformation of animal tissue cells |
Publications (1)
Publication Number | Publication Date |
---|---|
GR3026594T3 true GR3026594T3 (en) | 1998-07-31 |
Family
ID=23738164
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR980400787T GR3026594T3 (en) | 1989-11-16 | 1998-04-10 | Particle mediated transformation of animal skin tissue cells |
Country Status (11)
Country | Link |
---|---|
US (6) | US6194389B1 (el) |
EP (1) | EP0500799B1 (el) |
JP (2) | JPH05503841A (el) |
AT (1) | ATE162219T1 (el) |
AU (1) | AU6964191A (el) |
CA (1) | CA2068863C (el) |
DE (1) | DE69031951T2 (el) |
DK (1) | DK0500799T3 (el) |
ES (1) | ES2113371T3 (el) |
GR (1) | GR3026594T3 (el) |
WO (1) | WO1991007487A1 (el) |
Families Citing this family (98)
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EP0500799B1 (en) | 1989-11-16 | 1998-01-14 | Duke University | Particle mediated transformation of animal skin tissue cells |
US6706694B1 (en) | 1990-03-21 | 2004-03-16 | Vical Incorporated | Expression of exogenous polynucleotide sequences in a vertebrate |
US6228844B1 (en) | 1991-11-12 | 2001-05-08 | Vical Incorporated | Stimulating vascular growth by administration of DNA sequences encoding VEGF |
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US4945050A (en) | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
US5100792A (en) | 1984-11-13 | 1992-03-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues |
US4806463A (en) | 1986-05-23 | 1989-02-21 | Worcester Foundation For Experimental Biology | Inhibition of HTLV-III by exogenous oligonucleotides |
US4704692A (en) | 1986-09-02 | 1987-11-03 | Ladner Robert C | Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides |
US5015580A (en) | 1987-07-29 | 1991-05-14 | Agracetus | Particle-mediated transformation of soybean plants and lines |
IL84459A (en) | 1986-12-05 | 1993-07-08 | Agracetus | Apparatus and method for the injection of carrier particles carrying genetic material into living cells |
US4944942A (en) | 1987-08-27 | 1990-07-31 | Mobay Corporation | Intranasal vaccination of horses with inactivated microorganisms or antigenic material |
US4945000A (en) * | 1989-01-18 | 1990-07-31 | Btl Specialty Resins Corp. | Particulate thermosetting adhesive compositions |
US5703055A (en) * | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
EP1026253B2 (en) | 1989-03-21 | 2012-12-19 | Vical Incorporated | Expression of exogenous polynucleotide sequences in a vertebrate |
JP3573454B2 (ja) * | 1989-06-26 | 2004-10-06 | パウダージェクト ヴァクシンズ,インコーポレイテッド | 動物の体細胞の粒子媒介形質転換 |
EP0500799B1 (en) | 1989-11-16 | 1998-01-14 | Duke University | Particle mediated transformation of animal skin tissue cells |
US5204253A (en) * | 1990-05-29 | 1993-04-20 | E. I. Du Pont De Nemours And Company | Method and apparatus for introducing biological substances into living cells |
AU705889B2 (en) * | 1993-08-26 | 1999-06-03 | Regents Of The University Of California, The | Method, compositions and devices for administration of naked polynucleotides which encode antigens and immunostimulatory peptides |
US5703057A (en) * | 1995-04-07 | 1997-12-30 | Board Of Regents The University Of Texas System | Expression library immunization |
JP4430135B2 (ja) | 1995-11-30 | 2010-03-10 | バイカル インコーポレイテッド | カチオン脂質複合体 |
US5994317A (en) | 1996-04-09 | 1999-11-30 | Vical Incorporated | Quaternary cytofectins |
-
1990
- 1990-11-13 EP EP91901057A patent/EP0500799B1/en not_active Expired - Lifetime
- 1990-11-13 AT AT91901057T patent/ATE162219T1/de not_active IP Right Cessation
- 1990-11-13 AU AU69641/91A patent/AU6964191A/en not_active Abandoned
- 1990-11-13 DE DE69031951T patent/DE69031951T2/de not_active Expired - Lifetime
- 1990-11-13 WO PCT/US1990/006597 patent/WO1991007487A1/en active IP Right Grant
- 1990-11-13 ES ES91901057T patent/ES2113371T3/es not_active Expired - Lifetime
- 1990-11-13 JP JP3501470A patent/JPH05503841A/ja active Pending
- 1990-11-13 DK DK91901057T patent/DK0500799T3/da active
- 1990-11-13 CA CA002068863A patent/CA2068863C/en not_active Expired - Lifetime
-
1997
- 1997-04-11 US US08/840,224 patent/US6194389B1/en not_active Expired - Fee Related
-
1998
- 1998-04-10 GR GR980400787T patent/GR3026594T3/el unknown
-
2000
- 2000-08-21 JP JP2000250310A patent/JP2001103968A/ja not_active Withdrawn
-
2001
- 2001-01-08 US US09/755,199 patent/US20020006637A1/en not_active Abandoned
-
2003
- 2003-07-02 US US10/610,651 patent/US7449449B2/en not_active Expired - Fee Related
- 2003-07-02 US US10/610,601 patent/US7358234B2/en not_active Expired - Fee Related
-
2004
- 2004-03-05 US US10/792,934 patent/US20040170616A1/en not_active Abandoned
-
2007
- 2007-11-19 US US11/984,545 patent/US20080138325A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP0500799A4 (en) | 1993-05-05 |
WO1991007487A1 (en) | 1991-05-30 |
DE69031951T2 (de) | 1998-08-13 |
US7449449B2 (en) | 2008-11-11 |
DK0500799T3 (da) | 1998-09-14 |
ES2113371T3 (es) | 1998-05-01 |
US20040097458A1 (en) | 2004-05-20 |
EP0500799A1 (en) | 1992-09-02 |
US20080138325A1 (en) | 2008-06-12 |
EP0500799B1 (en) | 1998-01-14 |
AU6964191A (en) | 1991-06-13 |
US20040170616A1 (en) | 2004-09-02 |
US20040092019A1 (en) | 2004-05-13 |
JP2001103968A (ja) | 2001-04-17 |
US20020006637A1 (en) | 2002-01-17 |
ATE162219T1 (de) | 1998-01-15 |
US7358234B2 (en) | 2008-04-15 |
CA2068863A1 (en) | 1991-05-17 |
DE69031951D1 (de) | 1998-02-19 |
CA2068863C (en) | 2009-06-02 |
US6194389B1 (en) | 2001-02-27 |
JPH05503841A (ja) | 1993-06-24 |
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