GR3023379T3 - Novel N-sustituted azaheterocyclic carboxylic acids - Google Patents

Novel N-sustituted azaheterocyclic carboxylic acids

Info

Publication number
GR3023379T3
GR3023379T3 GR970401032T GR970401032T GR3023379T3 GR 3023379 T3 GR3023379 T3 GR 3023379T3 GR 970401032 T GR970401032 T GR 970401032T GR 970401032 T GR970401032 T GR 970401032T GR 3023379 T3 GR3023379 T3 GR 3023379T3
Authority
GR
Greece
Prior art keywords
novel
carboxylic acids
sustituted
azaheterocyclic carboxylic
pyrrolyl
Prior art date
Application number
GR970401032T
Other languages
English (en)
Inventor
Lars Jacob Stray Knutsen
Anker Steen Jorgensen
Knud Erik Andersen
Ursula Sonnewald
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of GR3023379T3 publication Critical patent/GR3023379T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Bipolar Transistors (AREA)
GR970401032T 1988-12-19 1997-05-09 Novel N-sustituted azaheterocyclic carboxylic acids GR3023379T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK704488A DK704488D0 (da) 1988-12-19 1988-12-19 Nye n-substituerede azaheterocykliske carboxylsyrer

Publications (1)

Publication Number Publication Date
GR3023379T3 true GR3023379T3 (en) 1997-08-29

Family

ID=8149197

Family Applications (1)

Application Number Title Priority Date Filing Date
GR970401032T GR3023379T3 (en) 1988-12-19 1997-05-09 Novel N-sustituted azaheterocyclic carboxylic acids

Country Status (16)

Country Link
US (1) US5071859A (el)
EP (1) EP0374801B1 (el)
JP (1) JP2848534B2 (el)
AT (1) ATE150455T1 (el)
AU (1) AU634992B2 (el)
CA (1) CA2005919C (el)
DE (1) DE68927875T2 (el)
DK (1) DK704488D0 (el)
ES (1) ES2099067T3 (el)
FI (1) FI93951C (el)
GR (1) GR3023379T3 (el)
IL (1) IL92652A0 (el)
NO (1) NO177672C (el)
NZ (1) NZ231836A (el)
PT (1) PT92628B (el)
ZA (1) ZA899736B (el)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4910312A (en) * 1985-11-08 1990-03-20 Warner-Lambert Company Various N-substituted 3-piperidine carboxylic acids or N-substituted 3-pyridinecarboxylic acids and derivatives thereof
DE3609699A1 (de) * 1986-03-20 1987-09-24 Schering Ag 5- oder 6-substituierte-(beta)-carbolin-3-carbonsaeureester
US5214054A (en) * 1988-05-18 1993-05-25 Novo Nordisk A/S Azacyclic carboxylic acid derivatives and their preparation and use
FR2653123B1 (fr) * 1989-10-17 1992-01-17 Roussel Uclaf Nouveaux derives de la pyridone, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
DK588189D0 (da) * 1989-11-22 1989-11-22 Novo Nordisk As Nye heterocykliske carboxylsyrer
DE4017211A1 (de) * 1990-05-29 1991-12-05 Merck Patent Gmbh Oxazolidinone
DK181190D0 (da) * 1990-07-30 1990-07-30 Lundbeck & Co As H 3-aryl-indol- eller 3-aryl-indazolderivater
DE4117904A1 (de) * 1991-05-31 1992-12-03 Basf Ag Substituierte n-phenylpiperidine
DK93791D0 (da) * 1991-05-17 1991-05-17 Novo Nordisk As Nye heterocykliske carboxylsyrer
EP0535496A1 (en) * 1991-09-25 1993-04-07 Hoechst-Roussel Pharmaceuticals Incorporated (1-Indanon-2yl)methylpiperidines, intermediates and a process for their preparation and their use as medicaments
EP0543780A3 (en) * 1991-11-21 1993-09-01 Ciba-Geigy Ag Novel aminoalkanephosphinic acids and their salts
US5633250A (en) * 1991-12-18 1997-05-27 Schering Corporation Imidazoylalkyl substituted with a six or seven membered heterocyclic ring containing two nitrogen atoms
MY110108A (en) * 1991-12-18 1998-01-27 Schering Corp Imidazolyl or imidazolylalkyl substituted with a four or five membered nitrigen containing heterocyclic ring
US5932596A (en) * 1991-12-18 1999-08-03 Schering Corporation Imidazoylalkyl substituted with a six membered nitrogen containing nitrogen containing heterocyclic ring
US5807872A (en) * 1992-12-16 1998-09-15 Schering Corporation Imidazoylalkyl substituted with a six membered nitrogen containing heterocyclic ring
GB9127306D0 (en) * 1991-12-23 1992-02-19 Boots Co Plc Therapeutic agents
US5284957A (en) * 1992-09-03 1994-02-08 Eli Lilly And Company Excitatory amino acid receptor antagonists
US5286733A (en) * 1992-11-20 1994-02-15 Sterling Winthrop Inc. Substituted 3-piperidinealkanoates and alkanones and compositions and method of use thereof
US5580877A (en) * 1994-04-25 1996-12-03 Merck Sharp & Dohme Ltd. Pyrazolo-quinoline derivatives for treating cerebral ischemia
US5962449A (en) 1995-04-07 1999-10-05 Novo Nordisk A/S Tricyclic compounds in treating hyperalgesic conditions and NIDDM
FR2735476B1 (fr) * 1995-06-14 1997-07-18 Rhone Poulenc Rorer Sa Nouvelle application de derives du pyrrole
US5747523A (en) * 1996-01-24 1998-05-05 Guilford Pharmaceuticals Inc. Substituted ethyl α,α-diarylmethyl ether derivatives
AU1506499A (en) * 1997-12-12 1999-07-05 Toyama Chemical Co. Ltd. Alkyl ether derivatives or salts thereof and calcium antagonists containing the same
DE19840611A1 (de) * 1998-09-05 2000-03-09 Klaus Wanner GABA-uptake-Inhibitoren mit Pyrrolidinstruktur
US7026335B2 (en) * 2002-04-30 2006-04-11 The Procter & Gamble Co. Melanocortin receptor ligands
US20040010010A1 (en) * 2002-04-30 2004-01-15 Ebetino Frank Hallock Melanocortin receptor ligands
KR20230048003A (ko) * 2020-07-02 2023-04-10 씨 파마슈티컬즈 엘엘씨 6-(2-(2h-테트라졸-5-일)에틸)-6-플루오로데카하이드로이소퀴놀린-3-카복실산 및 그의 에스테르 유도체의 약학 조성물

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU552050B2 (en) * 1981-05-26 1986-05-22 Smithkline Beckman Corporation N-substituted azeheterocyclic carboxylic acids and their esters
US4383999A (en) * 1981-05-26 1983-05-17 Smithkline Beckman Corporation Inhibition of GABA uptake by N-substituted azaheterocyclic carboxylic acids and their esters
US4514414A (en) * 1982-10-25 1985-04-30 Smithkline Beckman Corporation N-Substituted pyrrolidineacetic acids and their esters
FI83957C (fi) * 1984-09-28 1991-09-25 Byk Gulden Lomberg Chem Fab Foerfarande foer framstaellning av nya, terapeutiskt anvaendbara diarylfoereningar.
DK288385D0 (da) * 1985-06-26 1985-06-26 Novo Industri As Aminosyrederivater
FI864246A (fi) * 1985-11-08 1987-05-09 Warner Lambert Co N-substituerade 3-piperidin- eller 3-pyridinkarboxylsyror samt deras derivat.
US4910312A (en) * 1985-11-08 1990-03-20 Warner-Lambert Company Various N-substituted 3-piperidine carboxylic acids or N-substituted 3-pyridinecarboxylic acids and derivatives thereof
DK165692C (da) * 1986-01-07 1993-11-08 Novo Nordisk As Phenylbutenderivater, fremgangsmaade til fremstilling heraf, farmaceutisk praeparat indeholdende disse, samt anvendelse af disse til fremstilling af et medikament nyttigt til inhibering af gaba-optagelse i mennesker
DK270488D0 (da) * 1988-05-18 1988-05-18 Novo Industri As Hidtil ukendte o-substituerede ketoximer

Also Published As

Publication number Publication date
ATE150455T1 (de) 1997-04-15
ES2099067T3 (es) 1997-05-16
JP2848534B2 (ja) 1999-01-20
EP0374801A3 (en) 1991-08-07
NO177672C (no) 1995-11-01
CA2005919C (en) 1997-01-07
FI93951C (fi) 1995-06-26
AU4688989A (en) 1990-06-21
JPH02223551A (ja) 1990-09-05
EP0374801A2 (en) 1990-06-27
PT92628A (pt) 1990-06-29
NO177672B (no) 1995-07-24
FI93951B (fi) 1995-03-15
AU634992B2 (en) 1993-03-11
NO895093L (no) 1990-06-20
CA2005919A1 (en) 1990-06-19
PT92628B (pt) 1995-09-12
DE68927875D1 (de) 1997-04-24
NZ231836A (en) 1992-11-25
US5071859A (en) 1991-12-10
DE68927875T2 (de) 1997-06-26
EP0374801B1 (en) 1997-03-19
DK704488D0 (da) 1988-12-19
FI896084A0 (fi) 1989-12-19
ZA899736B (en) 1990-09-26
NO895093D0 (no) 1989-12-18
IL92652A0 (en) 1990-08-31

Similar Documents

Publication Publication Date Title
ZA899736B (en) N-substituted azaheterocyclic carboxylic acids
ZA848714B (en) Antimicrobial compositions
AU631070B2 (en) Novel platelet-aggregation inhibitor
ES8307853A1 (es) "un metodo de preparar un disiloxano".
HK1011689A1 (en) Bis(3,4-dialkylbenzylidene) sorbitol acetals and compositions containing same
ES2153364T3 (es) Antimicoticos de tetrahidrofurano tri-sustituido.
ES2145003T3 (es) Composicion que contiene un derivado de dioxabiciclo(3.3.0)octano.
TW347389B (en) Taxoids, their preparation and pharmaceutical compositions containing them
EP0652211A4 (en) PROSTAGLANDIN DERIVATIVE.
KR900006380A (ko) 그래프트 공중합체의 제조방법
GR3036570T3 (en) 6-Azaindole thromboxane synthase inhibitors.
CO5011097A1 (es) Derivados de 8-azabiciclo [3.2.1]octan-3-metanamina .
DE68900990D1 (en) Thioformamid-derivate.
SG81900A1 (en) A method for making a, b-unsaturated-b-trifluoromethyl-carboxylates and related compounds
ES8307779A1 (es) "un derivado de la piperazina".