NO895093L - Fremgangsmaate for fremstilling av n-substituerte azaheterockliske carboxylsyrer. - Google Patents

Fremgangsmaate for fremstilling av n-substituerte azaheterockliske carboxylsyrer.

Info

Publication number
NO895093L
NO895093L NO89895093A NO895093A NO895093L NO 895093 L NO895093 L NO 895093L NO 89895093 A NO89895093 A NO 89895093A NO 895093 A NO895093 A NO 895093A NO 895093 L NO895093 L NO 895093L
Authority
NO
Norway
Prior art keywords
substituted
azaheterocklic
procedure
preparation
pyrrolyl
Prior art date
Application number
NO89895093A
Other languages
English (en)
Other versions
NO177672B (no
NO895093D0 (no
NO177672C (no
Inventor
Lars Jacob Stray Knutsen
Anker Steen Joergensen
Knud Erik Andersen
Ursula Sonnewald
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO895093D0 publication Critical patent/NO895093D0/no
Publication of NO895093L publication Critical patent/NO895093L/no
Publication of NO177672B publication Critical patent/NO177672B/no
Publication of NO177672C publication Critical patent/NO177672C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Bipolar Transistors (AREA)
NO895093A 1988-12-19 1989-12-18 Analogifremgangsmåte for fremstilling av terapeutisk aktive, N-substituerte azaheterocykliske karboksylsyrer og estere derav NO177672C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK704488A DK704488D0 (da) 1988-12-19 1988-12-19 Nye n-substituerede azaheterocykliske carboxylsyrer

Publications (4)

Publication Number Publication Date
NO895093D0 NO895093D0 (no) 1989-12-18
NO895093L true NO895093L (no) 1990-06-20
NO177672B NO177672B (no) 1995-07-24
NO177672C NO177672C (no) 1995-11-01

Family

ID=8149197

Family Applications (1)

Application Number Title Priority Date Filing Date
NO895093A NO177672C (no) 1988-12-19 1989-12-18 Analogifremgangsmåte for fremstilling av terapeutisk aktive, N-substituerte azaheterocykliske karboksylsyrer og estere derav

Country Status (16)

Country Link
US (1) US5071859A (no)
EP (1) EP0374801B1 (no)
JP (1) JP2848534B2 (no)
AT (1) ATE150455T1 (no)
AU (1) AU634992B2 (no)
CA (1) CA2005919C (no)
DE (1) DE68927875T2 (no)
DK (1) DK704488D0 (no)
ES (1) ES2099067T3 (no)
FI (1) FI93951C (no)
GR (1) GR3023379T3 (no)
IL (1) IL92652A0 (no)
NO (1) NO177672C (no)
NZ (1) NZ231836A (no)
PT (1) PT92628B (no)
ZA (1) ZA899736B (no)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4910312A (en) * 1985-11-08 1990-03-20 Warner-Lambert Company Various N-substituted 3-piperidine carboxylic acids or N-substituted 3-pyridinecarboxylic acids and derivatives thereof
DE3609699A1 (de) * 1986-03-20 1987-09-24 Schering Ag 5- oder 6-substituierte-(beta)-carbolin-3-carbonsaeureester
US5214054A (en) * 1988-05-18 1993-05-25 Novo Nordisk A/S Azacyclic carboxylic acid derivatives and their preparation and use
FR2653123B1 (fr) * 1989-10-17 1992-01-17 Roussel Uclaf Nouveaux derives de la pyridone, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
DK588189D0 (da) * 1989-11-22 1989-11-22 Novo Nordisk As Nye heterocykliske carboxylsyrer
DE4017211A1 (de) * 1990-05-29 1991-12-05 Merck Patent Gmbh Oxazolidinone
DK181190D0 (da) * 1990-07-30 1990-07-30 Lundbeck & Co As H 3-aryl-indol- eller 3-aryl-indazolderivater
DE4117904A1 (de) * 1991-05-31 1992-12-03 Basf Ag Substituierte n-phenylpiperidine
DK93791D0 (da) * 1991-05-17 1991-05-17 Novo Nordisk As Nye heterocykliske carboxylsyrer
EP0535496A1 (en) * 1991-09-25 1993-04-07 Hoechst-Roussel Pharmaceuticals Incorporated (1-Indanon-2yl)methylpiperidines, intermediates and a process for their preparation and their use as medicaments
EP0767174A1 (de) * 1991-11-21 1997-04-09 Ciba-Geigy Ag Neue Aminoalkanphosphinsäuren und ihre Salze
US5633250A (en) * 1991-12-18 1997-05-27 Schering Corporation Imidazoylalkyl substituted with a six or seven membered heterocyclic ring containing two nitrogen atoms
US5807872A (en) * 1992-12-16 1998-09-15 Schering Corporation Imidazoylalkyl substituted with a six membered nitrogen containing heterocyclic ring
US5932596A (en) * 1991-12-18 1999-08-03 Schering Corporation Imidazoylalkyl substituted with a six membered nitrogen containing nitrogen containing heterocyclic ring
WO1993012108A1 (en) * 1991-12-18 1993-06-24 Schering Corporation Imidazolyl or imidazoylalkyl substituted with a four or five membered nitrogen containing heterocyclic ring
GB9127306D0 (en) * 1991-12-23 1992-02-19 Boots Co Plc Therapeutic agents
US5284957A (en) * 1992-09-03 1994-02-08 Eli Lilly And Company Excitatory amino acid receptor antagonists
US5286733A (en) * 1992-11-20 1994-02-15 Sterling Winthrop Inc. Substituted 3-piperidinealkanoates and alkanones and compositions and method of use thereof
US5580877A (en) * 1994-04-25 1996-12-03 Merck Sharp & Dohme Ltd. Pyrazolo-quinoline derivatives for treating cerebral ischemia
US5962449A (en) 1995-04-07 1999-10-05 Novo Nordisk A/S Tricyclic compounds in treating hyperalgesic conditions and NIDDM
FR2735476B1 (fr) * 1995-06-14 1997-07-18 Rhone Poulenc Rorer Sa Nouvelle application de derives du pyrrole
US5747523A (en) * 1996-01-24 1998-05-05 Guilford Pharmaceuticals Inc. Substituted ethyl α,α-diarylmethyl ether derivatives
WO1999031056A1 (fr) * 1997-12-12 1999-06-24 Toyama Chemical Co., Ltd. Derives d'ether alcoylique ou leurs sels, et antagonistes du calcium les contenant
DE19840611A1 (de) * 1998-09-05 2000-03-09 Klaus Wanner GABA-uptake-Inhibitoren mit Pyrrolidinstruktur
US7026335B2 (en) * 2002-04-30 2006-04-11 The Procter & Gamble Co. Melanocortin receptor ligands
US20040010010A1 (en) * 2002-04-30 2004-01-15 Ebetino Frank Hallock Melanocortin receptor ligands
MX2022016223A (es) * 2020-07-02 2023-02-23 Sea Pharmaceuticals Llc Composiciones farmaceuticas de acido 6-(2-(2h-tetrazol-5-il)etil)- 6-fluorodecahidroisoquinolina-3-carboxilico y derivados de ester del mismo.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU552050B2 (en) * 1981-05-26 1986-05-22 Smithkline Beckman Corporation N-substituted azeheterocyclic carboxylic acids and their esters
US4383999A (en) * 1981-05-26 1983-05-17 Smithkline Beckman Corporation Inhibition of GABA uptake by N-substituted azaheterocyclic carboxylic acids and their esters
US4514414A (en) * 1982-10-25 1985-04-30 Smithkline Beckman Corporation N-Substituted pyrrolidineacetic acids and their esters
FI83957C (fi) * 1984-09-28 1991-09-25 Byk Gulden Lomberg Chem Fab Foerfarande foer framstaellning av nya, terapeutiskt anvaendbara diarylfoereningar.
DK288385D0 (da) * 1985-06-26 1985-06-26 Novo Industri As Aminosyrederivater
FI864246A (fi) * 1985-11-08 1987-05-09 Warner Lambert Co N-substituerade 3-piperidin- eller 3-pyridinkarboxylsyror samt deras derivat.
US4910312A (en) * 1985-11-08 1990-03-20 Warner-Lambert Company Various N-substituted 3-piperidine carboxylic acids or N-substituted 3-pyridinecarboxylic acids and derivatives thereof
IL81179A (en) * 1986-01-07 1992-02-16 Novo Nordisk As N-phenylbutenyl substituted azaheterocyclic carboxylic acids,their preparation and pharmaceutical compositions comprising them
DK270488D0 (da) * 1988-05-18 1988-05-18 Novo Industri As Hidtil ukendte o-substituerede ketoximer

Also Published As

Publication number Publication date
US5071859A (en) 1991-12-10
NO177672B (no) 1995-07-24
NZ231836A (en) 1992-11-25
AU4688989A (en) 1990-06-21
DE68927875T2 (de) 1997-06-26
FI93951C (fi) 1995-06-26
NO895093D0 (no) 1989-12-18
PT92628A (pt) 1990-06-29
JPH02223551A (ja) 1990-09-05
ATE150455T1 (de) 1997-04-15
FI93951B (fi) 1995-03-15
GR3023379T3 (en) 1997-08-29
NO177672C (no) 1995-11-01
FI896084A0 (fi) 1989-12-19
DK704488D0 (da) 1988-12-19
ES2099067T3 (es) 1997-05-16
CA2005919A1 (en) 1990-06-19
EP0374801B1 (en) 1997-03-19
JP2848534B2 (ja) 1999-01-20
IL92652A0 (en) 1990-08-31
ZA899736B (en) 1990-09-26
PT92628B (pt) 1995-09-12
EP0374801A2 (en) 1990-06-27
CA2005919C (en) 1997-01-07
EP0374801A3 (en) 1991-08-07
DE68927875D1 (de) 1997-04-24
AU634992B2 (en) 1993-03-11

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