GR3021952T3 - Triterpene derivatives and endothelin-receptor antagonists containing the same. - Google Patents
Triterpene derivatives and endothelin-receptor antagonists containing the same.Info
- Publication number
- GR3021952T3 GR3021952T3 GR960403369T GR960403369T GR3021952T3 GR 3021952 T3 GR3021952 T3 GR 3021952T3 GR 960403369 T GR960403369 T GR 960403369T GR 960403369 T GR960403369 T GR 960403369T GR 3021952 T3 GR3021952 T3 GR 3021952T3
- Authority
- GR
- Greece
- Prior art keywords
- endothelin
- same
- receptor antagonists
- triterpene derivatives
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/30—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
- C07C233/33—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/18—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by doubly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14041693 | 1993-06-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
GR3021952T3 true GR3021952T3 (en) | 1997-03-31 |
Family
ID=15268217
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR960403369T GR3021952T3 (en) | 1993-06-11 | 1996-12-10 | Triterpene derivatives and endothelin-receptor antagonists containing the same. |
Country Status (11)
Country | Link |
---|---|
US (2) | US5463107A (el) |
EP (2) | EP0628569B1 (el) |
JP (1) | JP2724114B2 (el) |
KR (1) | KR100201015B1 (el) |
CN (2) | CN1041938C (el) |
AT (2) | ATE142640T1 (el) |
DE (2) | DE69410081T2 (el) |
DK (1) | DK0628569T3 (el) |
ES (2) | ES2116663T3 (el) |
GR (1) | GR3021952T3 (el) |
TW (1) | TW272974B (el) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0628569B1 (en) | 1993-06-11 | 1996-09-11 | Shionogi & Co., Ltd. | Triterpene derivatives and endothelin-receptor antagonists containing the same |
EP0838223B1 (en) * | 1995-06-02 | 2003-07-23 | Shionogi & Co., Ltd. | Brain edema inhibitor |
AU1319697A (en) * | 1996-01-23 | 1997-08-20 | Shionogi & Co., Ltd. | Process for producing oleanolic acid analogs by culturing hairy root |
JP2007217438A (ja) * | 2001-07-17 | 2007-08-30 | Shionogi & Co Ltd | 注射用医薬製剤 |
TWI232102B (en) | 2001-07-17 | 2005-05-11 | Shionogi & Co | A pharmaceutical formulation for injection |
AU2003221074A1 (en) | 2002-03-22 | 2003-10-08 | Shionogi And Co., Ltd. | Process for producing triterpene derivative |
EP1629853A1 (en) * | 2003-06-04 | 2006-03-01 | SHIONOGI & CO., LTD. | Method for preparing powder exhibiting low susceptibility to electrification |
TWI335335B (en) * | 2004-03-24 | 2011-01-01 | Shionogi & Co | A novel crystal of a triterpene derivative |
JP4827189B2 (ja) | 2004-05-14 | 2011-11-30 | 塩野義製薬株式会社 | 過酸化水素およびタングステン触媒を用いたアルコールの酸化反応 |
WO2006077801A1 (ja) * | 2005-01-18 | 2006-07-27 | Shionogi & Co., Ltd. | ミリセロン誘導体の製造方法 |
EP1964556A4 (en) * | 2005-12-21 | 2010-03-24 | Shionogi & Co | THERAPEUTIC AGENT OR THERAPEUTIC PROCEDURE AGAINST ISCHEMIC STROKE |
WO2007103727A2 (en) * | 2006-03-03 | 2007-09-13 | Savipu Pharmaceuticals | Triterpene derivatives for the treatment of cancer and inflammatory disease by inhibition of nf-kb |
US20070207989A1 (en) * | 2006-03-03 | 2007-09-06 | Savipu Pharmaceuticals | Diterpene derivatives for the treatment of cardiovascular, cancer and inflammatory diseases |
US7323476B2 (en) * | 2006-03-03 | 2008-01-29 | Savipu Pharmaceuticals | Myriceric acid derivatives for the treatment of cancer, cardiovascular and inflammatory diseases |
US20070243273A1 (en) * | 2006-04-12 | 2007-10-18 | Savipu Pharmaceuticals | Reduction of the Deleterious Effects of Tobacco Smoking |
US20080017207A1 (en) * | 2006-07-18 | 2008-01-24 | Savipu Pharmaceuticals | Reduction of the Deleterious Effects of Tobacco Smoking by the Induction of Phase 2 Enzymes by Nerf2 |
US20080187608A1 (en) * | 2007-02-05 | 2008-08-07 | Savipu Pharmaceuticals | Enriched fractions from clary sage for the treatment of cancer, cardiovascular and inflammatory diseases |
US20090022821A1 (en) * | 2007-07-17 | 2009-01-22 | Inderjit Kumar Dev | Compositions from wax myrtle for the treatment of cancer, cardiovascular and inflammatory diseases |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2950616B2 (ja) | 1991-01-29 | 1999-09-20 | 塩野義製薬株式会社 | トリテルペン誘導体 |
EP0628569B1 (en) | 1993-06-11 | 1996-09-11 | Shionogi & Co., Ltd. | Triterpene derivatives and endothelin-receptor antagonists containing the same |
-
1994
- 1994-06-09 EP EP94304165A patent/EP0628569B1/en not_active Expired - Lifetime
- 1994-06-09 AT AT94304165T patent/ATE142640T1/de not_active IP Right Cessation
- 1994-06-09 TW TW083105247A patent/TW272974B/zh not_active IP Right Cessation
- 1994-06-09 DE DE69410081T patent/DE69410081T2/de not_active Expired - Lifetime
- 1994-06-09 ES ES95112524T patent/ES2116663T3/es not_active Expired - Lifetime
- 1994-06-09 DK DK94304165.7T patent/DK0628569T3/da active
- 1994-06-09 JP JP6127420A patent/JP2724114B2/ja not_active Expired - Fee Related
- 1994-06-09 DE DE69400506T patent/DE69400506T2/de not_active Expired - Lifetime
- 1994-06-09 ES ES94304165T patent/ES2094622T3/es not_active Expired - Lifetime
- 1994-06-09 AT AT95112524T patent/ATE165811T1/de not_active IP Right Cessation
- 1994-06-09 EP EP95112524A patent/EP0682009B1/en not_active Expired - Lifetime
- 1994-06-10 US US08/258,392 patent/US5463107A/en not_active Expired - Lifetime
- 1994-06-10 KR KR1019940013068A patent/KR100201015B1/ko not_active IP Right Cessation
- 1994-06-10 CN CN94102805A patent/CN1041938C/zh not_active Expired - Fee Related
-
1995
- 1995-07-26 US US08/507,211 patent/US5587505A/en not_active Expired - Lifetime
-
1996
- 1996-12-10 GR GR960403369T patent/GR3021952T3/el unknown
-
1998
- 1998-05-20 CN CN98109227A patent/CN1070183C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DK0628569T3 (da) | 1996-09-30 |
EP0682009A3 (en) | 1997-02-05 |
DE69400506T2 (de) | 1997-02-13 |
CN1041938C (zh) | 1999-02-03 |
CN1106368A (zh) | 1995-08-09 |
JPH0753484A (ja) | 1995-02-28 |
ATE142640T1 (de) | 1996-09-15 |
ATE165811T1 (de) | 1998-05-15 |
EP0682009A2 (en) | 1995-11-15 |
DE69400506D1 (de) | 1996-10-17 |
ES2116663T3 (es) | 1998-07-16 |
EP0682009B1 (en) | 1998-05-06 |
US5463107A (en) | 1995-10-31 |
JP2724114B2 (ja) | 1998-03-09 |
TW272974B (el) | 1996-03-21 |
KR100201015B1 (ko) | 1999-06-15 |
DE69410081T2 (de) | 1998-10-08 |
EP0628569B1 (en) | 1996-09-11 |
CN1070183C (zh) | 2001-08-29 |
DE69410081D1 (de) | 1998-06-10 |
CN1215725A (zh) | 1999-05-05 |
EP0628569A1 (en) | 1994-12-14 |
ES2094622T3 (es) | 1997-01-16 |
US5587505A (en) | 1996-12-24 |
KR950000663A (ko) | 1995-01-03 |
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