GR3007256T3 - - Google Patents

Info

Publication number
GR3007256T3
GR3007256T3 GR920403174T GR920403174T GR3007256T3 GR 3007256 T3 GR3007256 T3 GR 3007256T3 GR 920403174 T GR920403174 T GR 920403174T GR 920403174 T GR920403174 T GR 920403174T GR 3007256 T3 GR3007256 T3 GR 3007256T3
Authority
GR
Greece
Application number
GR920403174T
Other languages
Greek (el)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868628060A external-priority patent/GB8628060D0/en
Priority claimed from GB878715825A external-priority patent/GB8715825D0/en
Application filed filed Critical
Publication of GR3007256T3 publication Critical patent/GR3007256T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
GR920403174T 1986-11-24 1993-03-09 GR3007256T3 (forum.php)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868628060A GB8628060D0 (en) 1986-11-24 1986-11-24 Carboxylic acid compounds
GB878715825A GB8715825D0 (en) 1987-07-06 1987-07-06 3-pyrrolidinylthio-1-azabicyclo(3 2 0)hept-2-ene-2-carboxylic acid compounds

Publications (1)

Publication Number Publication Date
GR3007256T3 true GR3007256T3 (forum.php) 1993-07-30

Family

ID=26291578

Family Applications (1)

Application Number Title Priority Date Filing Date
GR920403174T GR3007256T3 (forum.php) 1986-11-24 1993-03-09

Country Status (6)

Country Link
US (3) US4921852A (forum.php)
EP (1) EP0272455B1 (forum.php)
JP (1) JP2555648B2 (forum.php)
DE (1) DE3784147T2 (forum.php)
ES (1) ES2053508T3 (forum.php)
GR (1) GR3007256T3 (forum.php)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4925838A (en) * 1988-03-18 1990-05-15 Fujisawa Pharmaceutical Company, Ltd. 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds
US4963544A (en) * 1988-05-23 1990-10-16 Fujisawa Pharmaceutical Company, Ltd. 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds
AU631671B2 (en) * 1989-08-04 1992-12-03 Banyu Pharmaceutical Co., Ltd. 2-(2-vinylpyrrolidinylthio)carbapenem derivatives
GB8923844D0 (en) * 1989-10-23 1989-12-13 Fujisawa Pharmaceutical Co Carbapenem compounds
US5112818A (en) * 1989-12-29 1992-05-12 Banyu Pharmaceutical Co., Ltd. 2-(2-cyclopropylpyrrolidin-4-ylthio)carbapenhem derivatives
JPH0764846B2 (ja) * 1990-03-27 1995-07-12 萬有製薬株式会社 2−(置換ピロリジニルチオ)カルバペネム誘導体
US5373002A (en) * 1990-03-27 1994-12-13 Banyu Pharmaceutical Co., Ltd. 2-(substituted pyrrolidinylthio) carbapenem derivatives
TW198034B (forum.php) * 1990-03-27 1993-01-11 Manyu Seiyaku Kk
US5374720A (en) * 1990-03-27 1994-12-20 Banyu Pharmaceutical Co., Ltd. 2-(substituted pyrrolidinylthio)carbapenem derivatives
WO1993006102A1 (fr) * 1991-09-27 1993-04-01 Banyu Pharmaceutical Co., Ltd. Derive de 2-(pyrrolidinylthio substitue) carbapenem
AU3904493A (en) * 1992-04-13 1993-11-18 Fujisawa Pharmaceutical Co., Ltd. Substituted 3-pyrrolidinylthio-carbapenems as antimicrobial agents
KR940007029A (ko) * 1992-09-02 1994-04-26 손정삼 새로운 카바페넴 유도체 및 그의 제조방법
AU4912393A (en) * 1993-06-15 1994-12-22 Dong Kook Pharmaceutical Co., Ltd. 1-beta-methyl-2-thiolic carbapenem derivatives
DE4321444A1 (de) * 1993-06-28 1995-01-05 Bernd Prof Dr Clement Pharmazeutische Zubereitung
ATE207922T1 (de) * 1994-02-25 2001-11-15 Banyu Pharma Co Ltd Carbapenem-derivate
GB9507203D0 (en) * 1995-04-07 1995-05-31 Smithkline Beecham Plc Novel compounds
CA2315056A1 (en) * 1997-12-16 1999-06-24 Terutaka Hashizume Carbapenem derivatives
KR20010079713A (ko) 1998-09-10 2001-08-22 마쓰자와 도로, 하야시 지로 카르바페넴 화합물
KR100325375B1 (ko) * 2000-01-31 2002-03-06 박호군 이미다졸린 고리가 치환된 카바페넴 유도체
CZ300137B6 (cs) * 2000-11-16 2009-02-18 Sankyo Company Limited Deriváty 1-methylkarbapenemu
EP2332527A3 (en) 2004-10-20 2011-11-16 Resverlogix Corp. Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases
CA2617213C (en) 2005-07-29 2014-01-28 Resverlogix Corp. Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
SI2118074T1 (sl) 2007-02-01 2014-05-30 Resverlogix Corp. Spojine za preprečevanje in zdravljenje kardiovaskularnih bolezni
CN101328179B (zh) * 2007-06-15 2011-01-12 山东轩竹医药科技有限公司 含有氧代氮杂环的巯基吡咯烷培南衍生物
DK2346837T3 (en) 2008-06-26 2015-04-20 Resverlogix Corp Methods for preparing quinazolinone derivatives
ES2542835T3 (es) 2009-01-08 2015-08-12 Resverlogix Corporation Compuestos para la prevención y el tratamiento de enfermedades cardiovasculares
EP2408454B1 (en) 2009-03-18 2024-07-24 Resverlogix Corp. Novel anti-inflammatory agents
CN102458405B (zh) 2009-04-22 2017-06-23 雷斯韦洛吉克斯公司 新抗炎剂
MX352760B (es) 2011-09-09 2017-12-07 Merck Sharp & Dohme Corp Star Metodos para tratar infecciones intrapulmonares.
LT2773354T (lt) 2011-11-01 2019-08-12 Resverlogix Corp. Geriamosios greitai atsipalaiduojančios pakeistų chinozolinų vaisto formos
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
WO2014080291A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Biaryl derivatives as bromodomain inhibitors
AU2013365926B9 (en) 2012-12-21 2019-01-17 Zenith Epigenetics Ltd. Novel heterocyclic compounds as bromodomain inhibitors
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US9320740B2 (en) 2013-03-15 2016-04-26 Merck Sharp & Dohme Corp. Ceftolozane-tazobactam pharmaceutical compositions
CN110279698B (zh) 2013-03-15 2022-10-28 默沙东有限责任公司 头孢特咯瓒抗生素组合物
ES2800603T3 (es) 2013-09-09 2021-01-04 Merck Sharp & Dohme Tratamiento de infecciones con ceftolozano/tazobactam en sujetos con insuficiencia renal
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane
CN107530356A (zh) 2015-03-13 2018-01-02 雷斯韦洛吉克斯公司 用于治疗补体相关疾病之组合物及治疗方法
WO2021165927A1 (en) * 2020-02-21 2021-08-26 Wockhardt Bio Ag 2-cyanopyrroldines, -piperidines or -dazepines as hyperglycemic agents

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3766196A (en) * 1971-07-26 1973-10-16 Robins Co Inc A H 3-(2-pyridyl) pyrrolidines and pyrrolines
US4552873A (en) * 1981-08-19 1985-11-12 Sankyo Company Limited Carbapenem compounds, and compositions containing them
US4640915A (en) * 1982-03-29 1987-02-03 Fujisawa Pharmaceutical Co., Ltd. 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives
JPS5916892A (ja) * 1982-07-19 1984-01-28 Sankyo Co Ltd カルバペネム−3−カルボン酸誘導体およびその製法
KR900006449B1 (ko) * 1982-08-24 1990-08-31 상꾜 가부시끼가이샤 아제티디논 화합물의 제조방법
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
JPS60202886A (ja) * 1984-03-27 1985-10-14 Sankyo Co Ltd 1―置換カルバペネム―3―カルボン酸誘導体
DE3579888D1 (de) * 1984-11-08 1990-10-31 Sumitomo Pharma Carbapenemverbindungen und deren herstellung.
DE3821464A1 (de) * 1988-06-25 1989-12-28 Degussa Verfahren zur herstellung substituierter organyloxysilylfunktioneller, cyclischer thioharnstoffe und diese verbindungen

Also Published As

Publication number Publication date
US5138064A (en) 1992-08-11
JP2555648B2 (ja) 1996-11-20
EP0272455B1 (en) 1993-02-10
JPS63170379A (ja) 1988-07-14
DE3784147T2 (de) 1993-06-03
ES2053508T3 (es) 1994-08-01
DE3784147D1 (en) 1993-03-25
EP0272455A1 (en) 1988-06-29
US4921852A (en) 1990-05-01
US5420122A (en) 1995-05-30

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