GR3006406T3 - - Google Patents

Info

Publication number
GR3006406T3
GR3006406T3 GR920402770T GR920402770T GR3006406T3 GR 3006406 T3 GR3006406 T3 GR 3006406T3 GR 920402770 T GR920402770 T GR 920402770T GR 920402770 T GR920402770 T GR 920402770T GR 3006406 T3 GR3006406 T3 GR 3006406T3
Authority
GR
Greece
Prior art keywords
group
carbon atom
general formula
atom
single bond
Prior art date
Application number
GR920402770T
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GR3006406T3 publication Critical patent/GR3006406T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
GR920402770T 1987-02-23 1992-12-02 GR3006406T3 (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3784487 1987-02-23

Publications (1)

Publication Number Publication Date
GR3006406T3 true GR3006406T3 (el) 1993-06-21

Family

ID=12508841

Family Applications (1)

Application Number Title Priority Date Filing Date
GR920402770T GR3006406T3 (el) 1987-02-23 1992-12-02

Country Status (7)

Country Link
US (1) US4857537A (el)
EP (2) EP0461677B1 (el)
KR (1) KR960001205B1 (el)
AT (1) ATE151760T1 (el)
DE (2) DE3855875T2 (el)
ES (2) ES2103287T3 (el)
GR (1) GR3006406T3 (el)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01250370A (ja) * 1987-12-23 1989-10-05 Zeria Pharmaceut Co Ltd 新規アミノ酸イミド誘導体、製法ならびに用途
JP2515568B2 (ja) * 1987-12-25 1996-07-10 株式会社ヤクルト本社 新規なチアゾリジン誘導体
US5212191A (en) * 1988-04-08 1993-05-18 Ono Pharmaceutical Co., Ltd. Heterocyclic compounds
US5053414A (en) * 1988-04-08 1991-10-01 Ono Pharmaceutical Co., Ltd. Heterocyclic compounds
CA2004028C (en) * 1988-12-08 1998-09-22 Motoki Torizuka Condensed benzene derivative
WO1990012005A1 (en) * 1989-04-13 1990-10-18 Japan Tobacco Inc. New amino acid derivatives having prolylendopeptidase inhibitor activity
US5073549A (en) * 1990-03-22 1991-12-17 Bristol-Myers Squibb Company BU-4164E - A and B, prolyl endopeptidase inhibitors and their methods of use
US4999349A (en) * 1990-03-22 1991-03-12 Bristol-Myers Squibb Co. BU-4164E - A and B, prolyl endopeptidase inhibitors
CA2084412C (en) * 1990-06-04 2000-05-09 W. Stephen Faraci Pyrrolidine and thiazolidine amides
US5506256A (en) * 1990-07-27 1996-04-09 Yoshitomi Pharmaceutical Industries, Ltd. Proline derivatives possessing prolyl endopeptidase-inhibitory activity
IT1283782B1 (it) * 1996-08-09 1998-04-30 Ct Lab Farm Srl Uso di ammidi dell'acido gamma-idrossibutirrico nel trattamento di tossicodipendenze,ed in particolare sell'alcolismo
US6419857B1 (en) * 1999-12-06 2002-07-16 Baker Hughes Incorporated Thiazolidines and use thereof for corrosion inhibition
US7371871B2 (en) 2003-05-05 2008-05-13 Probiodrug Ag Inhibitors of glutaminyl cyclase
EP2338490A3 (en) 2003-11-03 2012-06-06 Probiodrug AG Combinations useful for the treatment of neuronal disorders
BRPI0507485A (pt) 2004-02-05 2007-07-10 Probiodrug Ag inibidores novos de glutaminil ciclase
EP1760076A1 (en) 2005-09-02 2007-03-07 Ferring B.V. FAP Inhibitors
US8278345B2 (en) 2006-11-09 2012-10-02 Probiodrug Ag Inhibitors of glutaminyl cyclase
JP5523107B2 (ja) 2006-11-30 2014-06-18 プロビオドルグ エージー グルタミニルシクラーゼの新規阻害剤
NZ579310A (en) 2007-03-01 2012-03-30 Probiodrug Ag Use of glutaminyl cyclase inhibitors for the treatment of mild cognitive impairment and diagnostic purposes thereof
EP2142514B1 (en) 2007-04-18 2014-12-24 Probiodrug AG Thiourea derivatives as glutaminyl cyclase inhibitors
CA2772488C (en) 2009-09-11 2018-04-17 Probiodrug Ag Heterocyclic derivatives as inhibitors of glutaminyl cyclase
US9181233B2 (en) 2010-03-03 2015-11-10 Probiodrug Ag Inhibitors of glutaminyl cyclase
US8269019B2 (en) 2010-03-10 2012-09-18 Probiodrug Ag Inhibitors
EP2560953B1 (en) 2010-04-21 2016-01-06 Probiodrug AG Inhibitors of glutaminyl cyclase
JP6050264B2 (ja) 2011-03-16 2016-12-21 プロビオドルグ エージー グルタミニルシクラーゼの阻害剤としてのベンゾイミダゾール誘導体
PL3461819T3 (pl) 2017-09-29 2020-11-30 Probiodrug Ag Inhibitory cyklazy glutaminylowej

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60188317A (ja) * 1984-03-09 1985-09-25 Yakult Honsha Co Ltd 抗健忘症剤
JPS6137764A (ja) * 1984-07-31 1986-02-22 Suntory Ltd 抗プロリルエンドペプチダ−ゼ活性を有する新規生理活性化合物
JPH0623190B2 (ja) * 1985-04-16 1994-03-30 サントリー株式会社 インヒビタ−活性を有するｎ−アシルピロリジン誘導体及びその製法並びに用途
CA1298033C (en) * 1985-04-16 1992-03-24 Takaharu Tanaka Dipeptide derivative of fatty acid
US4873342A (en) * 1985-04-16 1989-10-10 Suntory Limited Dipeptide derivative and synthesis and use thereof

Also Published As

Publication number Publication date
EP0280956B1 (en) 1992-10-21
DE3855875T2 (de) 1997-08-28
DE3855875D1 (de) 1997-05-22
DE3875361T2 (de) 1993-03-25
ES2103287T3 (es) 1997-09-16
KR880009949A (ko) 1988-10-06
DE3875361D1 (de) 1992-11-26
EP0461677B1 (en) 1997-04-16
EP0461677A1 (en) 1991-12-18
US4857537A (en) 1989-08-15
ATE151760T1 (de) 1997-05-15
KR960001205B1 (ko) 1996-01-24
EP0280956A1 (en) 1988-09-07
ES2052619T3 (es) 1994-07-16

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