GR1000421B - Νεα υποκατεστημενα παραγωγα αλκυλαμιδης της τεικοπλανινης. - Google Patents

Νεα υποκατεστημενα παραγωγα αλκυλαμιδης της τεικοπλανινης.

Info

Publication number
GR1000421B
GR1000421B GR900100195A GR900100195A GR1000421B GR 1000421 B GR1000421 B GR 1000421B GR 900100195 A GR900100195 A GR 900100195A GR 900100195 A GR900100195 A GR 900100195A GR 1000421 B GR1000421 B GR 1000421B
Authority
GR
Greece
Prior art keywords
teicoplanine
alkylamide
substituted derivatives
new substituted
derivatives
Prior art date
Application number
GR900100195A
Other languages
English (en)
Other versions
GR900100195A (en
Inventor
Romeo Ciabatti
Kurt Jurgen Kettenring
Adriano Malabarba
Pierfausto Seneci
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of GR900100195A publication Critical patent/GR900100195A/el
Publication of GR1000421B publication Critical patent/GR1000421B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Η παρούσα εφεύρεση αναφέρεται σε νέα C63 αμιδικά παράγωγα τεϊκοπλανίνης όπου η αμιδική ρίζα παράγεται απο μια δι-ή πολυ-αλκυλαμίνη και σε μέθοδο παρασκευής τους. Τα παράγωγα παρασκευάζονται δι'αντιδράσεως ενός προϊόντος παρομοίου προς την τεϊκοπλανίνη με αντιδραστήριο που σχηματίζει δραστικόν εστέρα όπως το χλωροακετονιτρίλιο και ακολούθως δι'επαφής του εν λόγω δραστικού εστέρα με την κατάλληλη δι-ή πολυ-αλκυλαμίνη. Τα αμιδικά παράγωγα της εφεύρεσης είναι δραστικά εναντίον θετικών και αρνητικών κατά gram βακτηριδίων. ω
GR900100195A 1989-03-29 1990-03-15 Νεα υποκατεστημενα παραγωγα αλκυλαμιδης της τεικοπλανινης. GR1000421B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP89105525 1989-03-29

Publications (2)

Publication Number Publication Date
GR900100195A GR900100195A (en) 1990-07-31
GR1000421B true GR1000421B (el) 1992-06-30

Family

ID=8201144

Family Applications (1)

Application Number Title Priority Date Filing Date
GR900100195A GR1000421B (el) 1989-03-29 1990-03-15 Νεα υποκατεστημενα παραγωγα αλκυλαμιδης της τεικοπλανινης.

Country Status (21)

Country Link
EP (1) EP0465481B1 (el)
JP (1) JP2833716B2 (el)
KR (1) KR0137958B1 (el)
CN (1) CN1045976A (el)
AU (1) AU638977B2 (el)
CA (1) CA2046880C (el)
DE (1) DE69004685T2 (el)
DK (1) DK0465481T3 (el)
ES (1) ES2060149T3 (el)
FI (1) FI914513A0 (el)
GR (1) GR1000421B (el)
HU (1) HU217074B (el)
IE (1) IE64155B1 (el)
IL (1) IL93716A (el)
NO (1) NO300068B1 (el)
NZ (1) NZ233135A (el)
PH (1) PH27258A (el)
PT (1) PT93445B (el)
RU (1) RU2078768C1 (el)
WO (1) WO1990011300A1 (el)
ZA (1) ZA901881B (el)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2224173T3 (es) * 1995-07-05 2005-03-01 Aventis Bulk S.P.A. Purificacion de antibioticos dalbaheptidos por enfoque isoelectrico.
AR021964A1 (es) * 1998-12-23 2002-09-04 Theravance Inc Un compuesto glicopeptidico, composiciones farmaceuticas que los contienen y uso de dichos compuestos glicopeptidicos para la manufactura de un medicamento antibacteriano.
AU768204B2 (en) 1998-12-23 2003-12-04 Cumberland Pharmaceuticals Inc. Glycopeptide derivatives and pharmaceutical compositions containing the same
ES2158770B1 (es) * 1999-02-03 2002-04-16 Smithkline Beecham Sa Nuevos glicopeptidos.
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US20060074014A1 (en) 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
US7119061B2 (en) 2002-11-18 2006-10-10 Vicuron Pharmaceuticals, Inc. Dalbavancin compositions for treatment of bacterial infections
AU2003294262B2 (en) 2002-11-18 2007-08-23 Vicuron Pharmaceuticals Inc. Methods of administering dalbavancin for treatment of bacterial infections
EP1516626B1 (en) * 2003-09-17 2006-12-27 Alpharma APS A Teicoplanin composition with improved antibiotic activity
RU2570425C1 (ru) * 2014-12-22 2015-12-10 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт по изысканию новых антибиотиков имени Г.Ф. Гаузе" Химерные антибиотики на основе гликопептидов и 11,12-циклического карбоната азитромицина и способ их получения
JP2019063191A (ja) * 2017-09-29 2019-04-25 国立研究開発法人国立長寿医療研究センター 非細胞性根管充填材及び非細胞性歯組織再生促進キット

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8522574D0 (en) * 1985-09-12 1985-10-16 Lepetit Spa Amides of teicoplanin compounds
GB8704847D0 (en) * 1987-03-02 1987-04-08 Lepetit Spa Substituted alkylamides of teicoplanin compounds
GB8827202D0 (en) * 1988-11-22 1988-12-29 Lepetit Spa Process for preparing 63-carboxyamides of teicoplanin antibiotics

Also Published As

Publication number Publication date
FI914513A0 (fi) 1991-09-25
HU902355D0 (en) 1991-12-30
JP2833716B2 (ja) 1998-12-09
IE64155B1 (en) 1995-07-12
NO913764D0 (no) 1991-09-25
EP0465481B1 (en) 1993-11-18
IL93716A0 (en) 1990-12-23
PT93445A (pt) 1990-11-07
DE69004685D1 (de) 1993-12-23
PH27258A (en) 1993-05-04
AU5188390A (en) 1990-10-22
WO1990011300A1 (en) 1990-10-04
ZA901881B (en) 1990-12-28
NO913764L (no) 1991-09-25
IL93716A (en) 1994-10-21
AU638977B2 (en) 1993-07-15
JPH04504251A (ja) 1992-07-30
DK0465481T3 (da) 1994-02-21
ES2060149T3 (es) 1994-11-16
NO300068B1 (no) 1997-04-01
KR920701251A (ko) 1992-08-11
DE69004685T2 (de) 1994-05-26
KR0137958B1 (ko) 1998-04-30
IE900808L (en) 1990-09-29
PT93445B (pt) 1996-08-30
GR900100195A (en) 1990-07-31
HU217074B (hu) 1999-11-29
CA2046880C (en) 2001-12-04
HUT58350A (en) 1992-02-28
CN1045976A (zh) 1990-10-10
CA2046880A1 (en) 1990-09-30
EP0465481A1 (en) 1992-01-15
NZ233135A (en) 1992-09-25
RU2078768C1 (ru) 1997-05-10

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