GEP201706775B - Method for selection of agents influencing intestinal motility disorders and pain - Google Patents

Method for selection of agents influencing intestinal motility disorders and pain

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Publication number
GEP201706775B
GEP201706775B GEAP201313744A GEAP2013013744A GEP201706775B GE P201706775 B GEP201706775 B GE P201706775B GE AP201313744 A GEAP201313744 A GE AP201313744A GE AP2013013744 A GEAP2013013744 A GE AP2013013744A GE P201706775 B GEP201706775 B GE P201706775B
Authority
GE
Georgia
Prior art keywords
agents
pain
selection
intestinal motility
motility disorders
Prior art date
Application number
GEAP201313744A
Other languages
English (en)
Inventor
Eamonn Connolly
Wolfgang Kunze
John Bienenstock
Original Assignee
Biogaia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49115523&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GEP201706775(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogaia Ab filed Critical Biogaia Ab
Publication of GEP201706775B publication Critical patent/GEP201706775B/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/13Edge detection
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11Medicinal preparations comprising living procariotic cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225Lactobacillus
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30092Stomach; Gastric

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Rheumatology (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)
  • Quality & Reliability (AREA)
  • Toxicology (AREA)
  • Radiology & Medical Imaging (AREA)
GEAP201313744A 2012-09-03 2013-09-03 Method for selection of agents influencing intestinal motility disorders and pain GEP201706775B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261696277P 2012-09-03 2012-09-03

Publications (1)

Publication Number Publication Date
GEP201706775B true GEP201706775B (en) 2017-11-27

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
GEAP201313744A GEP201706775B (en) 2012-09-03 2013-09-03 Method for selection of agents influencing intestinal motility disorders and pain

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US (5) US9555065B2 (enExample)
EP (2) EP3369808A1 (enExample)
JP (3) JP6259458B2 (enExample)
KR (1) KR102293438B1 (enExample)
CN (4) CN108904545A (enExample)
AU (1) AU2013308299B2 (enExample)
CA (2) CA3268968A1 (enExample)
CL (2) CL2015000490A1 (enExample)
CO (1) CO7350654A2 (enExample)
DK (1) DK2893045T3 (enExample)
ES (1) ES2681974T3 (enExample)
GE (1) GEP201706775B (enExample)
HK (1) HK1258778A1 (enExample)
HR (1) HRP20181033T1 (enExample)
IL (2) IL237397B (enExample)
IN (1) IN2015DN01572A (enExample)
LT (1) LT2893045T (enExample)
MX (2) MX362495B (enExample)
MY (2) MY195532A (enExample)
NZ (1) NZ705358A (enExample)
PH (1) PH12015500452B1 (enExample)
RU (1) RU2701348C2 (enExample)
SG (3) SG10201608055XA (enExample)
SI (1) SI2893045T1 (enExample)
UA (2) UA118339C2 (enExample)
WO (1) WO2014033330A1 (enExample)
ZA (1) ZA201501472B (enExample)

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BR112013002667B1 (pt) 2010-08-04 2020-02-04 Thomas Julius Borody composições para transplante da flora intestinal e métodos para fazê-las e usá-las e dispositivos para administrá-las
CN108094541A (zh) * 2018-01-11 2018-06-01 黑龙江完达山林海液奶有限公司 一种具有保健益生功能的风味发酵乳及其制备方法
CN117487686A (zh) * 2018-07-24 2024-02-02 生命大地女神有限公司 选择和使用褪黑素支持细菌以减少婴儿绞痛
WO2020247568A1 (en) * 2019-06-05 2020-12-10 Avl Powertrain Engineering, Inc. Vehicle axle assembly
EP3980285A1 (en) 2019-06-05 2022-04-13 AVL Powertrain Engineering, Inc. Vehicle frame assembly and power supply tray
US12263752B2 (en) 2019-06-05 2025-04-01 Avl Mobility Technologies, Inc. Vehicle frame and power supply assembly and related systems and methods
CN110186922B (zh) * 2019-06-25 2021-07-23 西安交通大学医学院第一附属医院 一种监测结肠移行性复合运动的实验装置及方法
US11843097B2 (en) 2019-09-10 2023-12-12 Avl Powertrain Engineering, Inc. Power supply control systems and methods
CN112710823B (zh) * 2020-12-17 2024-03-29 中国科学院深圳先进技术研究院 一种肠移行性复合运动的离体检测系统及其应用
CN114342878B (zh) * 2022-01-10 2022-09-30 南京鼓楼医院 一种慢传输型便秘动物模型的建立方法
CN117384804A (zh) * 2023-12-12 2024-01-12 北京三元食品股份有限公司 格氏乳杆菌b1-26及其应用

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US5438989A (en) * 1990-08-10 1995-08-08 Hochman; Darryl Solid tumor, cortical function, and nerve tissue imaging methods and device
TR200100361T2 (tr) * 1998-08-21 2001-06-21 Novartis Ag Yeni oral formülasyon
CZ200213A3 (cs) * 1999-07-06 2002-08-14 Enpharma L. P. Prostředky k regulaci motility zaľívací soustavy a přijímání potravy
DK1565547T4 (da) * 2002-06-28 2013-01-14 Biosearch S A Probiotiske stammer, en fremgangsmåde til selektion deraf, præparater deraf samt anvendelse deraf
EP1384483A1 (en) * 2002-07-23 2004-01-28 Nestec S.A. Probiotics for treatment of irritable bowel disease (IBS) through improvement of gut neuromuscular function
TWI241912B (en) * 2002-10-30 2005-10-21 Food Industry Res & Dev Inst Novel Acid-and bile salt-resistant Lactobacillus isolates having the ability to lower and assimilate cholesterol
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US20090233888A1 (en) * 2005-03-23 2009-09-17 Usc Stevens, University Of Southern California Treatment of disease conditions through modulation of hydrogen sulfide produced by small intestinal bacterial overgrowth
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JP5019563B2 (ja) * 2006-06-16 2012-09-05 旭化成ケミカルズ株式会社 腸内細菌賦活剤
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Publication number Publication date
AU2013308299A1 (en) 2015-03-26
EP3369808A1 (en) 2018-09-05
JP6259458B2 (ja) 2018-01-10
CN108904545A (zh) 2018-11-30
SG11201501297TA (en) 2015-03-30
PH12015500452A1 (en) 2015-04-20
SG10201608055XA (en) 2016-11-29
RU2015112102A (ru) 2016-10-20
MY195532A (en) 2023-01-31
US20170114422A1 (en) 2017-04-27
HK1258774A1 (zh) 2019-11-22
CN108753645A (zh) 2018-11-06
US20220306984A1 (en) 2022-09-29
MX362495B (es) 2019-01-21
AU2013308299B2 (en) 2019-04-18
IN2015DN01572A (enExample) 2015-07-03
CO7350654A2 (es) 2015-08-10
HK1211848A1 (en) 2016-06-03
RU2701348C2 (ru) 2019-09-26
JP2018090616A (ja) 2018-06-14
NZ705358A (en) 2018-09-28
JP2018029588A (ja) 2018-03-01
HRP20181033T1 (hr) 2018-08-24
US20190112676A1 (en) 2019-04-18
MY182358A (en) 2021-01-20
CA3268968A1 (en) 2025-11-29
PH12015500452B1 (en) 2023-01-20
KR20150048201A (ko) 2015-05-06
HK1258778A1 (zh) 2019-11-22
IL259652B (en) 2020-03-31
UA126374C2 (uk) 2022-09-28
CA2883440A1 (en) 2014-03-06
CN108753645B (zh) 2019-10-22
CN104918640A (zh) 2015-09-16
JP2015529329A (ja) 2015-10-05
ES2681974T3 (es) 2018-09-17
KR102293438B1 (ko) 2021-08-25
CL2015000490A1 (es) 2015-05-29
US9555065B2 (en) 2017-01-31
CN104918640B (zh) 2019-03-19
DK2893045T3 (en) 2018-07-30
LT2893045T (lt) 2018-07-25
ZA201501472B (en) 2016-06-29
US9816150B2 (en) 2017-11-14
IL259652A (en) 2018-07-31
SG10202101556WA (en) 2021-03-30
IL237397B (en) 2018-10-31
US20180023150A1 (en) 2018-01-25
MX2015002792A (es) 2015-05-07
JP6476328B2 (ja) 2019-02-27
US20150231186A1 (en) 2015-08-20
CL2017002826A1 (es) 2018-04-06
MX2018013097A (es) 2020-09-02
EP2893045B1 (en) 2018-05-16
UA118339C2 (uk) 2019-01-10
CN109966511A (zh) 2019-07-05
JP6322326B2 (ja) 2018-05-09
EP2893045A1 (en) 2015-07-15
US10174388B2 (en) 2019-01-08
IL237397A0 (en) 2015-04-30
SI2893045T1 (en) 2018-08-31
WO2014033330A1 (en) 2014-03-06

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