MX362495B - Un metodo para la seleccion de agentes que afectan los trastornos de motilidad intestinal y el dolor. - Google Patents
Un metodo para la seleccion de agentes que afectan los trastornos de motilidad intestinal y el dolor.Info
- Publication number
- MX362495B MX362495B MX2015002792A MX2015002792A MX362495B MX 362495 B MX362495 B MX 362495B MX 2015002792 A MX2015002792 A MX 2015002792A MX 2015002792 A MX2015002792 A MX 2015002792A MX 362495 B MX362495 B MX 362495B
- Authority
- MX
- Mexico
- Prior art keywords
- intestinal motility
- selection
- motility disorders
- treatment
- agent
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 230000008991 intestinal motility Effects 0.000 title abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 208000035475 disorder Diseases 0.000 title 1
- 210000005036 nerve Anatomy 0.000 abstract 3
- 238000004458 analytical method Methods 0.000 abstract 2
- 230000001580 bacterial effect Effects 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 230000002496 gastric effect Effects 0.000 abstract 2
- 210000004556 brain Anatomy 0.000 abstract 1
- 238000010304 firing Methods 0.000 abstract 1
- 230000005176 gastrointestinal motility Effects 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 238000013507 mapping Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/0002—Inspection of images, e.g. flaw detection
- G06T7/0012—Biomedical image inspection
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/10—Segmentation; Edge detection
- G06T7/13—Edge detection
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/225—Lactobacillus
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30092—Stomach; Gastric
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- General Physics & Mathematics (AREA)
- Theoretical Computer Science (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Rheumatology (AREA)
- Pathology (AREA)
- Medical Informatics (AREA)
- Urology & Nephrology (AREA)
- Nutrition Science (AREA)
- Toxicology (AREA)
- Radiology & Medical Imaging (AREA)
- Quality & Reliability (AREA)
Abstract
Se proporciona un método para evaluar los agentes para el tratamiento de diferentes trastornos de motilidad intestinal, usando distintas partes metodológicas relacionadas con la musculatura y los nervios del tracto GI que se comunican con el cerebro. Particularmente, la presente invención proporciona un método para la selección de un agente efectivo para el tratamiento de un trastorno de motilidad intestinal, donde el método comprende: a) una etapa de mapeo espaciotemporal (ST, por sus siglas en inglés) realizado en un segmento gastrointestinal para analizar el efecto de dicho agente en la motilidad gastrointestinal; y b) una etapa de grabación del haz nervioso ex vivo realizada en un segmento gastrointestinal para analizar el efecto de dicho agente en la descarga del nervio aferente mesentérico. También se proporcionan las cepas bacterianas seleccionadas por los métodos de la invención y el uso de las cepas bacterianas en el tratamiento de los trastornos de motilidad intestinal motilidad.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261696277P | 2012-09-03 | 2012-09-03 | |
| PCT/EP2013/068202 WO2014033330A1 (en) | 2012-09-03 | 2013-09-03 | A method for selection of agents influencing intestinal motility disorders and pain |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015002792A MX2015002792A (es) | 2015-05-07 |
| MX362495B true MX362495B (es) | 2019-01-21 |
Family
ID=49115523
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015002792A MX362495B (es) | 2012-09-03 | 2013-09-03 | Un metodo para la seleccion de agentes que afectan los trastornos de motilidad intestinal y el dolor. |
| MX2018013097A MX2018013097A (es) | 2012-09-03 | 2015-03-03 | Un metodo para la seleccion de agentes que afectan los trastornos de motilidad intestinal y el dolor. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018013097A MX2018013097A (es) | 2012-09-03 | 2015-03-03 | Un metodo para la seleccion de agentes que afectan los trastornos de motilidad intestinal y el dolor. |
Country Status (27)
| Country | Link |
|---|---|
| US (5) | US9555065B2 (es) |
| EP (2) | EP2893045B1 (es) |
| JP (3) | JP6259458B2 (es) |
| KR (1) | KR102293438B1 (es) |
| CN (4) | CN109966511A (es) |
| AU (1) | AU2013308299B2 (es) |
| CA (1) | CA2883440A1 (es) |
| CL (2) | CL2015000490A1 (es) |
| CO (1) | CO7350654A2 (es) |
| DK (1) | DK2893045T3 (es) |
| ES (1) | ES2681974T3 (es) |
| GE (1) | GEP201706775B (es) |
| HK (3) | HK1211848A1 (es) |
| HR (1) | HRP20181033T1 (es) |
| IL (2) | IL237397B (es) |
| IN (1) | IN2015DN01572A (es) |
| LT (1) | LT2893045T (es) |
| MX (2) | MX362495B (es) |
| MY (2) | MY182358A (es) |
| NZ (1) | NZ705358A (es) |
| PH (1) | PH12015500452A1 (es) |
| RU (1) | RU2701348C2 (es) |
| SG (3) | SG10201608055XA (es) |
| SI (1) | SI2893045T1 (es) |
| UA (2) | UA118339C2 (es) |
| WO (1) | WO2014033330A1 (es) |
| ZA (1) | ZA201501472B (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ618935A (en) | 2010-08-04 | 2014-03-28 | Karma Medical Prod Co Ltd | Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them |
| CN108094541A (zh) * | 2018-01-11 | 2018-06-01 | 黑龙江完达山林海液奶有限公司 | 一种具有保健益生功能的风味发酵乳及其制备方法 |
| BR112020023868A2 (pt) | 2018-07-24 | 2021-04-06 | Biogaia Ab | Cepa bacteriana de ácido láctico, métodos para a seleção de uma cepa bacteriana de ácido láctico e para produzir melatonina em um indivíduo, produto de combinação, e, uso de uma cepa bacteriana de ácido láctico. |
| CN113966284B (zh) * | 2019-06-05 | 2024-09-10 | Avl移动技术公司 | 车辆轴组件 |
| CN110186922B (zh) * | 2019-06-25 | 2021-07-23 | 西安交通大学医学院第一附属医院 | 一种监测结肠移行性复合运动的实验装置及方法 |
| US11843097B2 (en) | 2019-09-10 | 2023-12-12 | Avl Powertrain Engineering, Inc. | Power supply control systems and methods |
| CN112710823B (zh) * | 2020-12-17 | 2024-03-29 | 中国科学院深圳先进技术研究院 | 一种肠移行性复合运动的离体检测系统及其应用 |
| CN114342878B (zh) * | 2022-01-10 | 2022-09-30 | 南京鼓楼医院 | 一种慢传输型便秘动物模型的建立方法 |
| CN117384804A (zh) * | 2023-12-12 | 2024-01-12 | 北京三元食品股份有限公司 | 格氏乳杆菌b1-26及其应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5438989A (en) * | 1990-08-10 | 1995-08-08 | Hochman; Darryl | Solid tumor, cortical function, and nerve tissue imaging methods and device |
| ES2257869T3 (es) * | 1998-08-21 | 2006-08-01 | Novartis Ag | Nueva formulacion oral para agonistas o antagonistas de 5-ht4. |
| IL147312A0 (en) * | 1999-07-06 | 2002-08-14 | Enpharma L P | Methods for compositions for regulating gut motility and food intake |
| NZ537706A (en) * | 2002-06-28 | 2008-03-28 | Puleva Biotech Sa | Probiotic microbial strains, comprising non-pathogenic strains which are capable of surviving in and being transferred to breast milk and/or amniotic fluid after oral intake in healthy individuals without colonizing other internal organs except mucousas |
| EP1384483A1 (en) * | 2002-07-23 | 2004-01-28 | Nestec S.A. | Probiotics for treatment of irritable bowel disease (IBS) through improvement of gut neuromuscular function |
| TWI241912B (en) * | 2002-10-30 | 2005-10-21 | Food Industry Res & Dev Inst | Novel Acid-and bile salt-resistant Lactobacillus isolates having the ability to lower and assimilate cholesterol |
| CN1663573B (zh) * | 2004-03-04 | 2010-04-28 | 青岛东海药业有限公司 | 一种稳定安全的微生态制剂及其制备方法和用途 |
| US20090233888A1 (en) * | 2005-03-23 | 2009-09-17 | Usc Stevens, University Of Southern California | Treatment of disease conditions through modulation of hydrogen sulfide produced by small intestinal bacterial overgrowth |
| JP5036020B2 (ja) * | 2005-11-30 | 2012-09-26 | 雪印メグミルク株式会社 | 腎周囲脂肪蓄積抑制剤 |
| US7374924B2 (en) * | 2006-06-05 | 2008-05-20 | Biogaia Ab | Use of selected lactic acid bacteria for reducing infantile colic |
| JP5019563B2 (ja) * | 2006-06-16 | 2012-09-05 | 旭化成ケミカルズ株式会社 | 腸内細菌賦活剤 |
| EP2200443B2 (en) * | 2007-09-17 | 2021-06-30 | Cornell University | Branched chain fatty acids for prevention or treatment of gastrointestinal disorders |
| CN102481323A (zh) * | 2009-07-31 | 2012-05-30 | 雀巢产品技术援助有限公司 | 含有益生菌和所选营养物的用于母乳喂养的婴幼儿或宠物的营养组合物 |
| US20110110905A1 (en) * | 2009-11-06 | 2011-05-12 | Ritchie Jennifer A | Infant Colic Supplement |
| WO2011148219A1 (en) * | 2010-05-28 | 2011-12-01 | Compagnie Gervais Danone | Probiotic strains for use in improving the enteric nervous system |
| US20120034198A1 (en) * | 2010-08-04 | 2012-02-09 | Microbios, Inc. | Carriers for storage and delivery of biologics |
| CN102304489B (zh) * | 2011-09-23 | 2013-06-12 | 北京龙科方舟生物工程技术有限公司 | 一株罗伊氏乳杆菌及其应用 |
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2013
- 2013-03-09 UA UAA201503061A patent/UA118339C2/uk unknown
- 2013-09-03 IN IN1572DEN2015 patent/IN2015DN01572A/en unknown
- 2013-09-03 AU AU2013308299A patent/AU2013308299B2/en active Active
- 2013-09-03 CN CN201910121265.XA patent/CN109966511A/zh active Pending
- 2013-09-03 NZ NZ705358A patent/NZ705358A/en unknown
- 2013-09-03 CN CN201380049249.5A patent/CN104918640B/zh not_active Expired - Fee Related
- 2013-09-03 CA CA2883440A patent/CA2883440A1/en active Pending
- 2013-09-03 GE GEAP201313744A patent/GEP201706775B/en unknown
- 2013-09-03 WO PCT/EP2013/068202 patent/WO2014033330A1/en active Application Filing
- 2013-09-03 MY MYPI2015700601A patent/MY182358A/en unknown
- 2013-09-03 SG SG10201608055XA patent/SG10201608055XA/en unknown
- 2013-09-03 MY MYPI2019004045A patent/MY195532A/en unknown
- 2013-09-03 EP EP13756897.8A patent/EP2893045B1/en active Active
- 2013-09-03 LT LTEP13756897.8T patent/LT2893045T/lt unknown
- 2013-09-03 EP EP18167810.3A patent/EP3369808A1/en active Pending
- 2013-09-03 KR KR1020157007682A patent/KR102293438B1/ko active IP Right Grant
- 2013-09-03 SI SI201331106T patent/SI2893045T1/en unknown
- 2013-09-03 CN CN201810593302.2A patent/CN108904545A/zh active Pending
- 2013-09-03 UA UAA201808043A patent/UA126374C2/uk unknown
- 2013-09-03 SG SG11201501297TA patent/SG11201501297TA/en unknown
- 2013-09-03 RU RU2015112102A patent/RU2701348C2/ru active
- 2013-09-03 CN CN201810593303.7A patent/CN108753645B/zh active Active
- 2013-09-03 DK DK13756897.8T patent/DK2893045T3/en active
- 2013-09-03 JP JP2015529067A patent/JP6259458B2/ja active Active
- 2013-09-03 ES ES13756897.8T patent/ES2681974T3/es active Active
- 2013-09-03 SG SG10202101556WA patent/SG10202101556WA/en unknown
- 2013-09-03 US US14/425,470 patent/US9555065B2/en active Active
- 2013-09-03 MX MX2015002792A patent/MX362495B/es active IP Right Grant
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2015
- 2015-02-24 IL IL237397A patent/IL237397B/en active IP Right Grant
- 2015-02-27 CL CL2015000490A patent/CL2015000490A1/es unknown
- 2015-03-02 PH PH12015500452A patent/PH12015500452A1/en unknown
- 2015-03-03 MX MX2018013097A patent/MX2018013097A/es unknown
- 2015-03-04 ZA ZA2015/01472A patent/ZA201501472B/en unknown
- 2015-03-25 CO CO15068564A patent/CO7350654A2/es unknown
- 2015-12-28 HK HK15112741.0A patent/HK1211848A1/xx not_active IP Right Cessation
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2016
- 2016-12-23 US US15/389,577 patent/US9816150B2/en active Active
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2017
- 2017-08-18 JP JP2017158075A patent/JP6322326B2/ja active Active
- 2017-09-15 US US15/705,922 patent/US10174388B2/en active Active
- 2017-11-08 CL CL2017002826A patent/CL2017002826A1/es unknown
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2018
- 2018-02-22 JP JP2018029505A patent/JP6476328B2/ja active Active
- 2018-05-28 IL IL259652A patent/IL259652B/en active IP Right Grant
- 2018-07-04 HR HRP20181033TT patent/HRP20181033T1/hr unknown
- 2018-12-12 US US16/217,507 patent/US20190112676A1/en not_active Abandoned
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2019
- 2019-01-23 HK HK19101138.0A patent/HK1258778A1/zh unknown
- 2019-01-23 HK HK19101134.4A patent/HK1258774A1/zh unknown
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2022
- 2022-06-15 US US17/840,923 patent/US20220306984A1/en not_active Abandoned
Also Published As
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