GB991654A - Adrenochrome monoaminoguanidine - Google Patents

Adrenochrome monoaminoguanidine

Info

Publication number
GB991654A
GB991654A GB19449/63A GB1944963A GB991654A GB 991654 A GB991654 A GB 991654A GB 19449/63 A GB19449/63 A GB 19449/63A GB 1944963 A GB1944963 A GB 1944963A GB 991654 A GB991654 A GB 991654A
Authority
GB
United Kingdom
Prior art keywords
adrenochrome
salts
compound
monoaminoguanidine
caustic soda
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB19449/63A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shiraimatsu Shinyaku KK
Original Assignee
Shiraimatsu Shinyaku KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shiraimatsu Shinyaku KK filed Critical Shiraimatsu Shinyaku KK
Publication of GB991654A publication Critical patent/GB991654A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/36—Oxygen atoms in position 3, e.g. adrenochrome

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises adrenochrome monoaminoguanidine and salts thereof with hydrohalic acids, monocarboxylic and sulphonic acids. The compound is prepared by mixing an aqueous solution of adrenochrome with a salt of aminoguanidine, e.g. the nitrate, together with a sufficient amount of a mineral acid to catalyse the reaction, and rendering the solution alkaline with ammonia or caustic soda to precipitate an orange-coloured product. The compound may be refined by dissolving in aqueous acetic acid and precipitating with caustic soda. Adrenochrome monoaminoguanidine and its salts have homostatic and capillary-stabilizing actions and are used in aqueous solutions as injections.
GB19449/63A 1962-05-25 1963-05-16 Adrenochrome monoaminoguanidine Expired GB991654A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2175562 1962-05-25

Publications (1)

Publication Number Publication Date
GB991654A true GB991654A (en) 1965-05-12

Family

ID=12063860

Family Applications (1)

Application Number Title Priority Date Filing Date
GB19449/63A Expired GB991654A (en) 1962-05-25 1963-05-16 Adrenochrome monoaminoguanidine

Country Status (4)

Country Link
CH (1) CH409962A (en)
DE (1) DE1470240A1 (en)
FR (1) FR2689M (en)
GB (1) GB991654A (en)

Also Published As

Publication number Publication date
DE1470240A1 (en) 1969-10-23
FR2689M (en) 1964-07-27
CH409962A (en) 1966-03-31

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